Assessment of Carotid Plaque Vulnerability Using Structural and Geometrical Determinants

Circulation Journal

Volumn 72, Issue 7, 2008, Pages 1092-1099

  Li, Zhi Yong ^a,b,c   Tang, Tjun ^a   U King Im, Jean ^a   Graves, Martin ^a   Sutcliffe, Michael ^b   Gillard, Jonathan H ^a  

^a ADDENBROOKE S HOSPITAL   (United Kingdom)

^b UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^c CAMBRIDGE UNIVERSITY HOSPITALS NHS FOUNDATION TRUST   (United Kingdom)

Author keywords

Atherosclerosis; Carotid artery; MRI; Plaque vulnerability; Structural analysis

Indexed keywords

LIPID;

ADULT; AGED; ARTERY DIAMETER; ARTERY WALL; ARTICLE; ATHEROMA; ATHEROSCLEROTIC PLAQUE; CAROTID ARTERY; CLINICAL ARTICLE; CONTROLLED STUDY; CORRELATION COEFFICIENT; FEMALE; GEOMETRY; HUMAN; MALE; NUCLEAR MAGNETIC RESONANCE IMAGING; STATISTICAL SIGNIFICANCE; STRUCTURE ANALYSIS; THROMBOSIS;

AGED; AGED, 80 AND OVER; CAROTID ARTERIES; CAROTID STENOSIS; CORONARY ARTERY DISEASE; ELASTICITY; FEMALE; FINITE ELEMENT ANALYSIS; HUMANS; MAGNETIC RESONANCE IMAGING; MALE; MIDDLE AGED; MODELS, CARDIOVASCULAR; MYOCARDIAL ISCHEMIA; STRESS, MECHANICAL;

EID: 46849096078     PISSN: 13469843     EISSN: 13474820     Source Type: Journal    
DOI: 10.1253/circj.72.1092     Document Type: Article

References (35)

1. Choy PC, Siow YL, Mymin D, O K. Lipids and atherosclerosis. Biochem Cell Biol 2004; 82: 212-224.
2. European Carotid Surgery Trialists' Collaborative Group. MRC European Carotid Surgery Trial: Interim results for symptomatic patients with severe (70-99%) or with mild (0-29%) carotid stenosis. Lancet 1991; 337: 1235-1243.
3. North American Symptomatic Carotid Endarterectomy Trial Collaborators. Beneficial effect of carotid endarterectomy in symptomatic patients with high-grade carotid stenosis. N Engl J Med 1991; 325: 445-453.
4. Halliday A, Mansfield A, Marro J, Peto C, Peto R, Potter J, et al. Prevention of disabling and fatal strokes by successful carotid endarterectomy in patients without recent neurological symptoms: Randomised controlled trial. Lancet 2004; 363: 1491-1502.
5. Hatsukami TS, Ross R, Polissar NL, Yuan C. Visualization of fibrous cap thickness and rupture in human atherosclerotic carotid plaque in vivo with high-resolution magnetic resonance imaging. Circulation 2000; 102:959-964.
6. Lindstedt KA, Kovanen PT. Proteolysis of pericellular matrix: A process linking inflammation to plaque destabilization and rupture. Arterioscler Thromb Vasc Biol 2004; 24: 2205-2206.
7. Redgrave JN, Lovett JK, Gallagher PJ, Rothwell PM. Histological assessment of 526 symptomatic carotid plaques in relation to the nature and timing of ischemic symptoms: The Oxford plaque study. Circulation 2006; 113: 2320-2328.
8. Spagnoli LG, Mauriello A, Sangiorgi G, Fratoni S, Bonanno E, Schwartz RS, et al. Extracranial thrombotically active carotid plaque as a risk factor for ischemic stroke. JAMA 2004; 292: 1845-1852.
9. Takaya N, Yuan C, Chu B, Saam T, Underbill H, Cai J, et al. Association between carotid plaque characteristics and subsequent ischemic cerebrovascular events: A prospective assessment with MRI: Initial results. Stroke 2006; 37: 818-823.
10. Ouhlous M, Flach HZ, de Weert TT, Hendriks JM, van Sambeek MR, Dippel DW, et al. Carotid plaque composition and cerebral infarction: MR imaging study. Am J Neuroradiol 2005; 26: 1044-1049.
11. Kato M, Dote K, Sasaki S, Ueda K, Matsuda O, Nakano Y, et al. Coronary plaque vulnerability in metabolic syndrome: Assessment of carotid artery morphology in acute coronary syndrome. Circ J 2007; 71:1229-1233.
12. Seo Y, Watanabe S, Ishizu T, Moriyama N, Takeyasu N, Maeda H, et al. Echolucent carotid plaques as a feature in patients with acute coronary syndrome. Circ J 2006; 70: 1629-1634.
13. Richardson PD. Biomechanics of plaque rupture: Progress, problems, and new frontiers. Ann Biomed Eng 2002; 30: 524-536.
14. Naghavi M, Libby P, Falk E, Casscells SW, Litovsky S, Rumberger J, et al. From vulnerable plaque to vulnerable patient: A call for new definitions and risk assessment strategies: Part II. Circulation 2003; 108: 1772-1778.
15. Naghavi M, Libby P, Falk E, Casscells SW, Litovsky S, Rumberger J, et al. From vulnerable plaque to vulnerable patient: A call for new definitions and risk assessment strategies: Part I. Circulation 2003; 108: 1664-1672.
16. Rohde LE, Lee RT. Pathophysiology of atherosclerotic plaque development and rupture: An overview. Semin Vasc Med 2003; 3: 347-354.
17. Cheng GC, Loree HM, Kamm RD, Fishbein MC, Lee RT. Distribution of circumferential stress in raptured and stable atherosclerotic lesions: A structural analysis with histopathological correlation. Circulation 1993; 87: 1179-1187.
18. Lee RT. Atherosclerotic lesion mechanics versus biology. Z Kardiol 2000; 89(Suppl 2): 80-84.
19. Loree HM, Kamm RD, Stringfellow RG, Lee RT. Effects of fibrous cap thickness on peak circumferential stress in model atherosclerotic vessels. Circ Res 1992; 71: 850-858.
20. Lee RT, Loree HM, Cheng GC, Lieberman EH, Jaramillo N, Schoen FJ. Computational structural analysis based on intravascular ultrasound imaging before in vitro angioplasty: Prediction of plaque fracture locations. J Am Coll Cardiol 1993; 21: 777-782.
21. Huang H, Virmani R, Younis H, Burke AP, Kamm RD, Lee RT. The impact of calcification on the biomechanical stability of atherosclerotic plaques. Circulation 2001; 103: 1051-1056.
22. Tang D, Yang C, Zheng J, Woodard PK, Sicard GA, Saffitz JE, et al. 3D MRI-based multicomponent FSI models for atherosclerotic plaques. Ann Biomed Eng 2004; 32: 947-960.
23. Imoto K, Hiro T, Fujii T, Murashige A, Fukumoto Y, Hashimoto G, et al. Longitudinal structural determinants of atherosclerotic plaque vulnerability: A computational analysis of stress distribution using vessel models and three-dimensional intravascular ultrasound imaging. J Am Coll Cardiol 2005; 46: 1507-1515.
24. Li ZY, Howarth SP, Tang T, Gillard JH. How critical is fibrous cap thickness to carotid plaque stability?: A flow - plaque interaction model. Stroke 2006; 37: 1195-1199.
25. Cai J, Hatsukami TS, Ferguson MS, Kerwin WS, Saam T, Chu B, et al. In vivo quantitative measurement of intact fibrous cap and lipid-rich necrotic core size in atherosclerotic carotid plaque: Comparison of high-resolution, contrast-enhanced magnetic resonance imaging and histology. Circulation 2005; 112: 3437-3444.
26. Trivedi RA, U-King-Im J, Graves MJ, Horsley J, Goddard M, Kirkpatrick PJ, et al. Multi-sequence in vivo MRI can quantify fibrous cap and lipid core components in human carotid atherosclerotic plaques. Eur J Vasc Endovasc Surg 2004; 28: 207-213.
27. Li ZY, Howarth S, Trivedi RA, U-King-Im JM, Graves MJ, Brown A, et al. Stress analysis of carotid plaque rapture based on in vivo high resolution MRI. J Biomech 2006; 39: 2611-2622.
28. Ogden RW. Large deformation isotropic elasticity: On the correlation of theory and experiment for incompressible rubberlike solids. Proc R Soc Lond A 1972; 326: 565-584.
29. Li ZY, Howarth SP, Tang T, Graves MJ, U-King-Im J, Trivedi RA, et al. Structural analysis and magnetic resonance imaging predict plaque vulnerability: A study comparing symptomatic and asymptomatic individuals. J Vasc Surg 2007; 45: 768-775.
30. Pasterkamp G, Smits PC. Imaging of atherosclerosis: Remodelling of coronary arteries. J Cardiovasc Risk 2002; 9: 229-235.
31. Yuan C, Kerwin WS, Ferguson MS, Polissar N, Zhang S, Cai J, et al. Contrast-enhanced high resolution MRI for atherosclerotic carotid artery tissue characterization. J Magn Reson Imaging 2002; 15: 62-67.
32. Morrisett J, Vick W, Sharma R, Lawrie G, Reardon M, Ezell E, et al. Discrimination of components in atherosclerotic plaques from human carotid endarterectomy specimens by magnetic resonance imaging ex vivo. Magn Reson Imaging 2003; 21: 465-474.
33. Rohde L, Lee RT. Mechanical stress and strain and the vulnerable atherosclerotic lesion. In: Fuster V (editor). The vulnerable atherosclerotic plaque: Understanding, identification and modification. New York: Futura Publishing Company; 1999; 305-316.
34. Loree HM, Tobias BJ, Gibson LJ, Kamm RD, Small DM, Lee RT. Mechanical properties of model atherosclerotic lesion lipid pools. Arterioscler Thromb 1994; 14: 230-234.
35. Li ZY, Howarth S, Tang T, Graves M, U-King-Im J, Gillard JH. Does calcium deposition play a role in the stability of atheroma?: Location may be the key. Cerebrovasc Dis 2007; 24: 452-459.