Synthesis of conformationally locked l-deoxythreosyl phosphonate nucleosides built on a bicyclo[3.1.0]hexane template

Journal of Organic Chemistry

Volumn 75, Issue 22, 2010, Pages 7659-7669

  Saneyoshi, Hisao ^a,c   Deschamps, Jeffrey R ^b   Marquez, Victor E ^a  

^a NATIONAL CANCER INSTITUTE   (United States)

^b NAVAL RESEARCH LABORATORY   (United States)

^c RIKEN   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CARBOCYCLIC NUCLEOSIDES; CONVENTIONAL APPROACH; CYCLOPROPANATION; DEOXYTHREOSYL PHOSPHONATE NUCLEOSIDES; DIPHOSPHATES; HIV REVERSE TRANSCRIPTASE; INTRAMOLECULAR CYCLOPROPANATIONS; LINEAR APPROACH; MICROWAVE REACTORS; PHOSPHONATES; PURINE RING; TRIPHOSPHATE;

AMIDES; HEXANE; LITHIUM COMPOUNDS; NUCLEIC ACID SEQUENCES; ORGANIC POLYMERS; SYNTHESIS (CHEMICAL);

BIOMOLECULES;

1 (6 AMINO 9H PURIN 9 YL)BICYCLO[3.1.0]HEXAN 3 OL CARBOCYCLIC NUCLEOSIDE; 1 AMINOBICYCLO[3.1.0.]HEXAN 3 YL BENZOATE; 4 (6 AMINO 9H PURIN 9 YL)BICYCLO[3.1.0]HEXAN 2 OL CARBOCYCLIC NUCLEOSIDE; 4 HYDROXY 2 CYCLOPENT 2 ENYL 1 YL ACETATE; [1 (6 AMINO 9H PURIN 9 YL)BICYCLO[3.1.0]HEXAN 3 YLOXY]METHYLPHOSPHONIC ACID; [4 (6 AMINO 9H PURIN 9 YL)BICYCLO[3.1.0]HEXAN 2 YLOXY]METHYLPHOSPHONIC ACID; ACETIC ACID; ADENOSINE TRIPHOSPHATE; BENZOIC ACID; BISPHOSPHONIC ACID DERIVATIVE; NUCLEOSIDE; NUCLEOSIDE TRIPHOSPHATE; PHOSPHONIC ACID DERIVATIVE; PURINE; RNA DIRECTED DNA POLYMERASE; UNCLASSIFIED DRUG;

ARTICLE; ENANTIOMER; MICROWAVE RADIATION; MITSUNOBU REACTION; SIMMONS SMITH REACTION; SYNTHESIS;

BICYCLO COMPOUNDS; MOLECULAR CONFORMATION; MOLECULAR STRUCTURE; NUCLEOSIDES; STEREOISOMERISM; SUGAR PHOSPHATES;

EID: 78449247453     PISSN: 00223263     EISSN: 15206904     Source Type: Journal    
DOI: 10.1021/jo101475p     Document Type: Article

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