A chiral-anion generator: Application to catalytic desilylative kinetic resolution of silyl-protected secondary alcohols

Angewandte Chemie - International Edition

Volumn 49, Issue 47, 2010, Pages 8915-8917

  Yan, Hailong ^a   Jang, Hyeong Bin ^a   Lee, Ji Woong ^b   Kim, Hong Ki ^a   Lee, Soon Won ^a,b   Yang, Jung Woon ^a   Song, Choong Eui ^a  

^a Sungkyunkwan University   (South Korea)

^b MAX PLANCK INSTITUT FÜR KOHLENFORSCHUNG   (Germany)

Author keywords

asymmetric catalysis; chirality; fluorides; kinetic resolution; polyethers

Indexed keywords

2-NAPHTHOLS; ASYMMETRIC CATALYSIS; ENANTIOSELECTIVE; FLUORIDES; KINETIC RESOLUTION; RACEMIC ALCOHOLS; SECONDARY ALCOHOLS; STRUCTURAL MOTIFS;

CATALYSIS; CHIRALITY; ENANTIOMERS; ETHERS; FLUORINE COMPOUNDS; PHENOLS; STEREOCHEMISTRY;

POLYETHERS;

EID: 78449238729     PISSN: 14337851     EISSN: 15213773     Source Type: Journal    
DOI: 10.1002/anie.201004777     Document Type: Article

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27. To understand the effect of halogen substituents on the catalytic activity and enantioselectivity in more detail and to explain the observed sense of stereoselectivity, computational studies are currently underway in our laboratory.