Bone marrow transplantation for adults with acute leukaemia and 11q23 chromosomal abnormalities

British Journal of Haematology

Volumn 103, Issue 3, 1998, Pages 630-638

  Forrest, D L ^a   Nevill, T J ^a,b   Horsman, D E ^a   Brockington, D A ^a   Fung, H C ^a   Toze, C L ^a   Conneally, E A ^a   Hogge, D E ^a   Sutherland, H J ^a   Nantel, S H ^a   Shepherd, J D ^a   Barnett, M J ^a  

^a UNIVERSITY OF BRITISH COLUMBIA   (Canada)

^b VANCOUVER HOSPITAL AND HEALTH SCIENCES CENTRE   (Canada)

Author keywords

Acute leukaemia; Bone marrow transplantation; Chromosome 11q23; Conventional chemotherapy

Indexed keywords

ACICLOVIR; AMPHOTERICIN B; ANTIBIOTIC AGENT; ANTINEOPLASTIC AGENT; CYCLOPHOSPHAMIDE; CYCLOSPORIN; CYTARABINE; DAUNORUBICIN; ETOPOSIDE; FLUCONAZOLE; GRANULOCYTE COLONY STIMULATING FACTOR; METHOTREXATE; MITOX; MITOXANTRONE; PREDNISONE; UNCLASSIFIED DRUG; VINCRISTINE;

ACUTE LEUKEMIA; ADOLESCENT; ADULT; AGED; ALLOGENIC BONE MARROW TRANSPLANTATION; ARTICLE; AUTOLOGOUS BONE MARROW TRANSPLANTATION; BONE MARROW TRANSPLANTATION; CANCER CHEMOTHERAPY; CANCER MORTALITY; CANCER RADIOTHERAPY; CANCER SURVIVAL; CHROMOSOME 11Q; CHROMOSOME ABERRATION; CLINICAL ARTICLE; DRUG MEGADOSE; FEMALE; HUMAN; INTRAVENOUS DRUG ADMINISTRATION; MALE; PRIORITY JOURNAL; RETROSPECTIVE STUDY;

ACUTE DISEASE; ADOLESCENT; ADULT; AGED; ANTINEOPLASTIC COMBINED CHEMOTHERAPY PROTOCOLS; BONE MARROW TRANSPLANTATION; CHROMOSOME ABERRATIONS; CHROMOSOMES, HUMAN, PAIR 11; COMBINED MODALITY THERAPY; DISEASE-FREE SURVIVAL; FEMALE; HUMANS; LEUKEMIA; MALE; MIDDLE AGED; RETROSPECTIVE STUDIES; TRANSPLANTATION, HOMOLOGOUS; TREATMENT OUTCOME;

EID: 7844245779     PISSN: 00071048     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2141.1998.01030.x     Document Type: Article

References (50)

1. Allouche, M., Georgoulias, V., Bourinbaiar, A., Dupuy, I., Clemenceau, C., Gaget, H., Mathe, G. & Jasmin, C. (1989) Bone marrow transplantation following busulphan, cyclophosphamide and high-dose cytarabine-arabinoside as treatment for infants with translocation (4:11) acute leukaemia. British Journal of Haematology 65, 411-418.
2. Arthur, D.C., Berger, R. & Golomb, H.M. (1989) The clinical significance of karyotype in acute myelogenons leukemia. Cancer Genetics and Cytogenetics, 40, 203-216.
3. Attal, M., Huguet, F., Rubie, H., Huynh, A., Charlet, J.P., Payen, J.L., Voigt, J.J., Brousset, P., Selves, J., Muller, C., Pris, J. & Laurent, G. (1992) Prevention of hepatic veno-occlusive disease after bone marrow transplantation by continuous infusion of low-dose heparin: a prospective, randomized trial. Blood, 79, 2834-2840.
4. Bloomfield, C.D., Goldman, A.I., Alimena, G., Berger, R., Borgstrom, G.H., Brandt, L., Catovsky, D., de la Chapelle, A., Dewald, G.W., Garson, O.M., Garwicz, S., Golomb, H.M., Hossfeld, D.K., Lawler, D.S., Mitelman, F., Nilsson, P., Pierre, R.V., Philip, P., Prigogina, E., Rowley, H.D., Sakurai, M., Sandberg, A.A., Secker Walker, L.M., Tricot, G., Van Den Berghe, H., Van Orshoven, A., Vuopio, P. & Whang-Peng, J. (1986) Chromosomal abnormalities identify high-risk and low-risk patients with acute lymphoblastic leukemia. Blood, 67, 415-420.
5. Bredeson, C.N., Barnett, M.J., Horsman, D.E., Dalal, B.I., Ragaz, J. & Phillips, G.L. (1993) Therapy-related acute myelogenous leukemia associated with 11q23 chromosomal abnormalities and topoisomerase II inhibitors: report of four additional cases and brief commentary. Leukemia and Lymphoma, 11, 141-145.
6. Buchner, T. & Heinecke, A. (1996) The role of prognostic factors in acute myeloid leukemia. Leukemia, 10, s28-s29.
7. Chen, C.-S., Sorensen, P.H.B., Domer, P.H., Reaman, G.H., Korsmeyer, S.J., Heerema, N.A., Hammond, G.D. & Kersey, J.H. (1993) Molecular rearrangements on chromosome 11q23 predominate in infant acute lymphoblastic leukemia and are associated with specific biologic variables and poor outcome. Blood, 81, 2386-2393.
8. Cimino, G., Rapanotti, M.C., Rivolta, A., LoCoco, F., D'Arcangelo, E., Rondelli, R., Basso, G., Barisone, E., Rosanda, C., Santostasi, T., Canaani, E., Masera, G., Mandelli, F. & Biondi, A. (1995) Prognostic relevance of ALL-1 gene rearrangement in infant acute leukemias. Leukemia, 9, 391-395.
9. Copelan, E.A., Kapoor, N., Murcek, M., Theil, K. & Tutschka, P.J. (1987) Marrow transplantation following busulphan and cyclophosphamide as treatment for translocation (4:11) acute leukaemia. British Journal of Haematology, 70, 127-128.
10. Cox, D.R. (1972) Regression models and life tables. Journal of the Royal Statistical Society (B), 34, 187-220.
11. Emminger, W., Emminger-Schmidmeier, W., Ambros, P., Haas, O.A., Hocker, P., Koller, U. & Gadner, H. (1991) Unusually long survival after autografting in second partial remission of translocation t(4:11) acute infant leukemia. Bone Marrow Transplantation, 8, 311-313.
12. Fenaux, P., Preudhomme, C., Lai, J.L., Morel, P., Beuscart, R. & Bauters, F. (1989) Cytogenetics and their prognostic value in de novo acute myeloid leukaemia: a report on 283 cases. British Journal of Haematology, 73, 61-67.
13. Ferrant, A., Labopin, M., Frassoni, F., Prentice, H.G., Cahn, J.Y., Blaise, D., Reiffers, J., Visani, G., Sanz, M.A., Boogaerts, M.A., Lowenberg, B. & Gorin, N.C. (1997) Karyotype in acute myeloblastic leukemia: prognostic significance for bone marrow transplantation in first remission. A European Group for Blood and Marrow Transplantation study. Blood, 90, 2931-2938.
14. Forman, S.J., Chao, N., Niland, J.C., Levitt, L., Champlin, R., Gajewski, J., Lee, J., Schiller, G., Nantel, S., Barnett, M., Levine, A., Saez, R., Phillips, G. & Blume, K.G. (1995) Intensive chemotherapy or bone marrow transplantation for adult ALL in first complete remission: a phase III trial. Blood, 86, Abstract 2453.
15. Gale, R.P., Horowitz, M.M., Biggs, J.C., Herzig, R.H., Kersey, J.H., Marmont, A.M., Masaoka, T., Rimm, A.A., Speck, B., Weiner, R.S., Zwaan, F.E. Bortin M.M. (1989) Transplant or chemotherapy in acute myelogenous leukaemia. Lancet, i, 1119-1122.
16. Gale, R.P., Horowitz, M.M., Weiner, R.S., Ash, R.C., Atkinson, K., Babu, R., Dicke, K.A., Klein, J.P., Lowenberg, B., Reiffers, J., Rimm, A.A., Rowlings, P.A., Sandberg, A.A., Sobocinski, K.A., Veum-Stone, J. & Bortin, M.M. (1995) Impact of cytogenetic abnormalities on outcome of bone marrow transplants in acute myelogenous leukemia in first remission. Bone Marrow Transplantation, 16, 203-208.
17. Gilmore, M.J.M.L., Hamon, M.D., Prentice, H.G., Katz., F. Slaper-Cortenbach, I.C.M., Hunter, A.E., Gandhi, L., Brenner, M.K., Hoffbrand, A.V., Mehta, A.B., Secker-Walker, L.M., Skeggs, D. & Collis, C.H. (1991) Failure of purged autologous bone marrow transplantation in high risk acute lymphoblastic leukemia in first complete remission. Bone Marrow Transplantation, 8, 19-26.
18. Harbott, J., Mancini, M., Verellen-Dumoulin, C.H., Moorman, A.V. & Secker-Walker, L.M. (1998) Hematological malignancies with a deletion of 11q23: cytogenetic and clinical aspects. Leukemia, 12, 823-827.
19. Heerema, N.A., Arthur, D.C., Sather, H., Albo, V., Feusner, J., Lange, B.J., Steinherz, P.G., Zeltzer, P., Hammond, D. & Reaman, G.H. (1994) Cytogenetic features of infants less than 12 months of age at diagnosis of acute lymphoblastic leukemia: impact of the 11q23 breakpoint on outcome. A report of the Childrens Cancer Group. Blood, 83, 2274-2284.
20. Heim, S. & Mitelman, F. (1992) Cytogenetic analysis in the diagnosis of acute leukemia. Cancer, 70, 1701-1709.
21. ISCN (1991) Guidelines for Cancer Cytogenetics: Supplement to An International System for Human Cytogenetic Nomenclature (ed. by F. Mitelman), S. Karger, Basel.
22. Johansson, B., Moorman, A.V., Haas, O.A., Watmore, A.E., Cheung, K.L., Swanton, S. & Seeker-Walker, L.M. (1998) Hematologic, malignancies with t(4;11)(q21;q23): a cytogenetic, morphologic, immunophenotypic and clinical study of 183 cases. Leukemia, 12, 779-787.
23. Kaplan, E.L. & Meier, P. (1958) Nonparametric estimation from incomplete observations. Journal of the American Statistical Association, 53, 457-481.
24. Kersey, J.H., Weisdorf, D., Nesbit, M.E., LeBien, T.W., Woods, W.G., McGlave, P.B., Kim, T., Vallera, D.A., Goldman, A.I., Bostrom, B., Hurd, D. & Ramsay, N.K.C. (1987) Comparison of autologous and allogeneic bone marrow transplantation for treatment of high-risk refractory acute lymphoblastic leukemia. New England Journal of Medicine, 317, 461-467.
25. Klingemann, H.-G., Eaves, C.J., Barnett, M.J., Eaves, A.C., Hogge, D.E., Nantel, S.H., Reece, D.E., Shepherd, J.D., Sutherland, H.J. & Phillips, G.L. (1994) Transplantation of patients with high risk acute myeloid leukemia in first remission with autologous marrow cultured in interleukin-2 followed by interleukin-2 administration. Bone Marrow Transplantation, 14, 389-396.
26. Marosi, C., Koller, U., Koller-Weber, E., Schwarzinger, I., Schneider, B., Jager, U., Vahls, P. Nowotny, H., Pirc-Danoewinata, H., Steger, G., Kreiner, G., Wagner, B., Lechner, K., Lutz, D., Bettelheim, P. & Haas, O.A. (1992) Prognostic impact of karyotype and immunologic phenotype in 125 adult patients with de novo AML. Cancer Genetics and Cytogenetics, 61, 14-25.
27. Moorman, A.V., Hagemeijer, A., Charrin, C., Rieder, H. & Secker-Walker, L.M. (1998) The translocations, t(11;19)(q23;p13.1) and t(11;19)(q23;p13.3): a cytogenetic and clinical profile of 53 patients. Leukemia, 12, 805-810.
28. Mrozek, K., Heinonen, K., Lawrence, D., Carroll, A.J., Koduru, P.R.K., Rao, K.W., Strout, M., Hutchison, R.E., Moore, J.O., Mayer, R.J., Schiffer, C.A. & Bloomfield, C.D. (1997) Adult patients with de novo acute myeloid leukemia and t(9:11)(p22;q23) have a superior outcome to patients with other translocations involving band 11q23: a Cancer and Leukemia Group B study. Blood, 90, 4532-4538.
29. Phillips, G.L., Nevill, T.J., Spinelli, J.J., Nantel, S.H., Klingemann, H.-G., Barnett, M.J., Shepherd, J.D., Chan, K., Meharchand, J.M., Sutherland, H.J., Reece, D.E. & Messner, H.A. (1995) Prophylaxis for acute graft-versus-host disease following unrelated-donor bone marrow transplantation. Bone Marrow Transplantation, 15, 213-219.
30. Schiffer, C.A., Lee, E.J. & Tomiyasu, T. (1989) Prognostic impact of cytogenetic abnormalities in patients with de novo acute nonlymphocytic leukemia. Blood, 73, 263-270.
31. Secker-Walker, L.M. (1998) General report on the European Union Concerted Action Workshop on 11q23. London, UK, May 1997. Leukemia, 12, 776-778.
32. Secker-Walker, L.M., Chessells, J.M., Stewart, E.L., Swansbury, G.J., Richards, S. & Lawler, S.D. (1989) Chromosomes and other prognostic factors in acute lymphoblastic leukaemia: a long-term follow-up. British Journal of Haematology, 72, 336-342.
33. Secker-Walker, L.M., Moorman, A.V., Bain, B.J. & Mehta, A.B. (1998) Secondary acute leukemia and myelodysplastic syndrome with 11q23 abnormalities. Leukemia, 12, 840-844.
34. Shepherd, J.D., Pringle, L.E., Barnett, M.J., Klingemann, H.-G., Reece, D.E. & Phillips, G.L. (1991) Mesna versus hyperhydration for the prevention of cyclophosphamide-induced hemorrhagic cystitis in bone marrow transplantation. Journal of Clinical Oncology, 9, 2016-2020.
35. Shepherd, J.D., Reece, D.E., Barnett, M.J., Klingemann, H.-G., Nantel, S.H., Sutherland, H.J. & Phillips, G.L. (1993) Induction therapy for acute myelogenous leukemia in patients over 60 years with intermediate-dose cytosine arabinoside, mitoxantrone and etoposide. Leukemia and Lymphoma, 9, 211-215.
36. Shepherd, J.D., Reece, D.E., Barnett, M.J., Nantel, S.H., Klingemann, H.-G., Sutherland, H.J., Spinelli, J.J. & Phillips, G.L. (1994) Induction chemotherapy with continuous infusion ara-C, mitoxantrone, and VP-16 for patients ≤65 with acute myeloid leukemia. Proceedings of the American Society of Clinical Oncology, 13, Abstract 1007.
37. Shepherd, J.D., Reece, D.E., Shore, T.B., Barnett, M.J., Bow, E.J., Nantel, S.H., Sutherland, H.J., Brockington, D.A., Fung, H.C., Spinelli, J.J., Klingemann, H.-G. & Phillips, G.I., (1995) High dose cytarabine, daunorubicin, and etoposide induction and consolidation therapy of acute myeloid leukemia in adults ≤ 60 years of age. Clinical and Investigative Medicine, 18, (Suppl. B), Abstract 611.
38. Shepherd, J.D., Shore, T.B., Reece, D.E., Barnett, M.J., Klingemann, H.-G., Buskard, N.A. & Phillips, G.L. (1988) Cyclosporine and methylprednisolone for prophylaxis of acute graft-versus-host disease. Bone Marrow Transplantation, 3, 553-558.
39. Sierra, J., Radich, J., Hansen, J.A., Martin, P.J., Petersdorf, E.W., Bjerke, J., Bryant, E., Nash, R.A., Sanders, J.E., Storb, R., Sullivan, K.M., Appelbaum, F.R. & Anasetti, C. (1997) Marrow transplants from unrelated donors for treatment of Philadelphia chromosome-positive acute lymphoblastic leukemia. Blood, 90, 1410-1414.
40. Simpson, D.R., Phillips, G.L., Thomas, T.E., Lansdorp, P.M., Barnett, M.J., Nantel, S.H., Shepherd, J.D., Shultz, K.R., Davis, J.H., Sutherland, H.J., Hogge, D.E., Toze, C.L. & Klingemann, H. (1996) Ex vivo depletion of T-lymphocytes by immuno-magnetic beads to decrease graft-versus-host disease after unrelated donor marrow transplantation. Blood, 88, Abstract 1667.
41. Sorensen, P.H.B., Chen, C.-S., Smith, F.O., Arthur, D.A., Domer, P.H., Bernstein, I.D., Korsmeyer, S.J., Hammond, G.D. & Kersey, J.H. (1994) Molecular rearrangements of the MLL gene are present in most cases of infant acute myeloid leukemia are strongly correlated with monocytic or myelomonocytic phenotypes. Journal of Clinical Investigation, 93, 429-437.
42. Stasi, R., Del-Poeta, G. & Masi, M. (1993) Incidence of chromosome abnormalities and clinical significance of karyotype in de novo acute myeloid leukemia. Cancer Genetics and Cytogenetics, 67, 28-34.
43. Storb, R., Deeg, H.J., Whitehead, J., Appelbaum, F., Beatty, P., Bensinger, W., Buckner, C.D., Clift, R., Doney, K., Farewell, V., Hansen, J., Hill, R., Lum, L., Martin, P., McGuffin, R., Sanders, J., Stewart, P., Sullivan, K., Witherspoon, R., Yee, G. & Thomas, E.D. (1986) Methotrexate and cyclosporine compared with cyclosporine alone for prophylaxis of acute graft versus host disease after marrow transplantation for leukemia. New England Journal of Medicine, 314, 729-735.
44. Storb, R., Pepe, M., Anasetti, C., Appelbaum, F.R., Beatty, P., Doney, K., Martin, P., Stewart, P., Sullivan, K.M., Witherspoon, R., Bensinger, W., Buckner, C.D., Clift, R., Hansen, J., Longton, G., Loughran, T., Petersen, F.B., Singer, J., Sanders, J. & Thomas, E.D. (1990) What role for prednisone in prevention of acute graft-versus-host disease in patients undergoing marrow transplants? Blood, 76, 1037-1045.
45. Swansbury, G.J., Slater, R., Bain, B.J., Moorman, A.V. & Secker-Walker, L.M. (1998) Hematological malignancies with t(9:11)(p21-22;q23): a laboratory and clinical study of 125 cases. Leukemia, 12, 792-800.
46. Taki, T., Ida, K., Bessho, F., Hanada, R., Kikuchi, A., Yamamoto, K., Sako, M., Tsuchida, M., Seto, M., Ueda, R. & Hayashi, Y. (1996) Frequency and clinical significance of the MLL gene rearrangements in infant acute leukemia. Leukemia, 10, 1303-1307.
47. Walters, R., Kantarjian, H.M., Keating, M.J., Estey, E.H., Trujillo, J., Cork, A., McCredic, K.B. & Reireich, E.J. (1990) The importance of cytogenetic studies in adult acute lymphocytic leukemia. American Journal of Medicine, 89, 579-587.
48. Yeager, A.M., Kaizer, H., Santos, G.W., Saral, R., Colvin, O.M., Stuart, R.K., Braine, H.G., Burke, P.J., Ambinder, R.F., Burns, W.H., Fuller, D.J., Davis, J.M., Karp, J.E., May, W.S., Rowley, S.D., Sensenbrenner, L.L., Vogelsang, G.B. & Wingard, J.R. (1986) Autologous bone marrow transplantation in patients with acute nonlymphocytic leukemia, using ex vivo marrow treatment with 4-hydroperoxycyclophosphamide. New England Journal of Medicine, 315, 141-147.
49. Zander, A.R., Keating, M., Dicke, K., Dixon, D., Pierce, S., Jagannath, S., Peters, L., Horwitz, L., Cockerill, K., Spitzer, G., Vellekoop, L., Kantarjian, H., Walters, R., McCredie, K. & Freireich, E.J. (1988) A comparison of marrow transplantation with chemotherapy for adults with acute leukemia of poor prognosis in first complete remission. Journal of Clinical Oncology, 6, 1548-1557.
50. Zhang, M.-J., Hoelzer, D., Horowitz, M.M., Gale, R.P., Messerer, D., Klein, J.P., Loffler, H., Sobocinski, K.A., Thiel, E. & Weisdorf, D.J. (1995) Long-term follow-up of adults with acute lymphoblastic leukemia in first remission treated with chemotherapy or hone marrow transplantation. Annals of Internal Medicine, 123, 428-431.