Preparation and characterization of hybrid pH-sensitive hydrogels of chitosan-co-acrylic acid for controlled release of verapamil

Journal of Materials Science: Materials in Medicine

Volumn 21, Issue 10, 2010, Pages 2805-2816

  Ranjha, Nazar M ^a   Ayub, Gohar ^b   Naseem, Shahzad ^c   Ansari, Muhammad Tayyab ^a  

^a BAHAUDDIN ZAKARIYA UNIVERSITY   (Pakistan)

^b Drugs Testing Laboratory   (Pakistan)

^c UNIVERSITY OF THE PUNJAB   (Pakistan)

Author keywords

[No Author keywords available]

Indexed keywords

ACIDIC PH; ACRYLIC ACIDS; AMINE GROUPS; ANIONIC GROUPS; AVERAGE MOLECULAR WEIGHT; BENZOYL PEROXIDE; BUFFER SOLUTIONS; CARBOXYLIC GROUP; CATIONIC GROUPS; CONTROLLED RELEASE; CROSS LINKING AGENTS; CROSS-LINKED HYDROGELS; CROSS-LINKING DENSITY; CROSSLINKING RATIO; CROSSLINKS; DEGREE OF CROSSLINKING; DIFFUSION COEFFICIENTS; DRUG RELEASE; EFFECT OF PH; ELECTROSTATIC INTERACTIONS; EQUILIBRIUM SWELLING; EXPERIMENTAL DATA; FEED COMPOSITIONS; FLORY-REHNER THEORY; FOURIER TRANSFORM INFRARED SPECTRA; FTIR; GEL FRACTION; HYDROGEL STRUCTURE; METHYLENEBISACRYLAMIDE; MODEL DRUGS; MODEL EQUATIONS; NETWORK PARAMETERS; NON-FICKIAN DIFFUSION; PH VALUE; PH-SENSITIVE HYDROGEL; PHOSPHATE BUFFER SOLUTIONS; POLYMER VOLUME FRACTION; RELEASE MECHANISM; REPEATING UNIT; SWELLING BEHAVIOR; SWELLING STUDIES; VERAPAMIL;

ACRYLICS; CARBOXYLIC ACIDS; CHITIN; CHITOSAN; CROSSLINKING; DRUG PRODUCTS; DYES; FOURIER TRANSFORMS; FREE RADICAL POLYMERIZATION; FREE RADICALS; GELS; IONIZATION; ORGANIC ACIDS; PARTICLE DETECTORS; PH EFFECTS; POLYMERS; POLYVINYL ALCOHOLS; POROSITY; SPECTROSCOPY; SWELLING;

HYDROGELS;

ACRYLIC ACID; AMINE; ANION; BENZOYL PEROXIDE; CARBOXYLIC ACID; CATION; CHITOSAN; N,N' METHYLENEBISACRYLAMIDE; VERAPAMIL;

ARTICLE; CHEMICAL STRUCTURE; CONTROLLED RELEASE FORMULATION; CROSS LINKING; DENSITY; DIFFUSION COEFFICIENT; DRUG RELEASE; GEL; HYDROGEL; INFRARED SPECTROSCOPY; IONIZATION; MOLECULAR WEIGHT; PH; POLYMERIZATION; POROSITY; PRIORITY JOURNAL; STATIC ELECTRICITY; THEORY;

ACRYLATES; BIOCOMPATIBLE MATERIALS; CHITOSAN; CROSS-LINKING REAGENTS; DELAYED-ACTION PREPARATIONS; DRUG CARRIERS; HYDROGELS; HYDROGEN-ION CONCENTRATION; MATERIALS TESTING; MICROSCOPY, ELECTRON, SCANNING; MOLECULAR WEIGHT; POROSITY; SPECTROSCOPY, FOURIER TRANSFORM INFRARED; STATIC ELECTRICITY; VERAPAMIL;

EID: 78349309102     PISSN: 09574530     EISSN: None     Source Type: Journal    
DOI: 10.1007/s10856-010-4134-1     Document Type: Article

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