Exploration of genetic susceptibility factors for Parkinson's disease in a South American sample

Journal of Genetics

Volumn 89, Issue 2, 2010, Pages 229-232

  Benitez, Bruno A ^a   Forero, Diego A ^a,b   Arboleda, Gonzalo H ^a   Granados, Luis A ^a   Yunis, Juan J ^a   Fernandez, William ^a   Arboleda, Humberto ^a  

^a UNIVERSIDAD NACIONAL DE COLOMBIA   (Colombia)

^b CENTRO DE INVESTIGACIONES   (Colombia)

Author keywords

candidate genes; human genetics; Latin America; Parkinson's disease; polymorphisms

Indexed keywords

ACE PROTEIN, HUMAN; ALPHA 2 MACROGLOBULIN; BRAIN DERIVED NEUROTROPHIC FACTOR; CATECHOL METHYLTRANSFERASE; DIPEPTIDYL CARBOXYPEPTIDASE; DOPAMINE TRANSPORTER; MAPT PROTEIN, HUMAN; SEROTONIN TRANSPORTER; SLC6A3 PROTEIN, HUMAN; SLC6A4 PROTEIN, HUMAN; TAU PROTEIN; UBIQUITIN THIOLESTERASE; UCHL1 PROTEIN, HUMAN;

AGED; ALLELE; ARTICLE; COLOMBIA; FEMALE; GENETIC MARKER; GENETIC POLYMORPHISM; GENETICS; GENOTYPE; HUMAN; MALE; MIDDLE AGED; ONSET AGE; PARKINSON DISEASE;

AGE OF ONSET; AGED; ALLELES; ALPHA-MACROGLOBULINS; BRAIN-DERIVED NEUROTROPHIC FACTOR; CATECHOL O-METHYLTRANSFERASE; COLOMBIA; DOPAMINE PLASMA MEMBRANE TRANSPORT PROTEINS; FEMALE; GENETIC MARKERS; GENOTYPE; HUMANS; MALE; MIDDLE AGED; PARKINSON DISEASE; PEPTIDYL-DIPEPTIDASE A; POLYMORPHISM, GENETIC; SEROTONIN PLASMA MEMBRANE TRANSPORT PROTEINS; TAU PROTEINS; UBIQUITIN THIOLESTERASE;

EID: 78349294117     PISSN: 00221333     EISSN: 09737731     Source Type: Journal    
DOI: 10.1007/s12041-010-0030-1     Document Type: Article

References (20)

1. Arboleda G. H., Yunis J. J., Pardo R., Gómez C. M., Hedmont D., Arango G. et al. 2001 Apolipoprotein E genotyping in a sample of Colombian patients with Alzheimer's disease. Neurosci. Lett. 305, 135-138.
2. Bagade S., Allen N. C., Tanzi R., Bertram L., Kavvoura F., Schjeide B. et al. 2009 The PDGene Database. Alzheimer. Res. (http://www. pdgene. org).
3. Bertram L., McQueen M. B., Mullin K., Blacker D. and Tanzi R. 2007 Systematic meta-analyses of Alzheimer disease genetic association studies: the AlzGene database. Nat. Genet. 39, 17-23.
4. Bodmer W. and Bonilla C. 2008 Common and rare variants in multifactorial susceptibility to common diseases. Nat. Genet. 40, 695-701.
5. Cook E. H., Stein M. A., Krasowski M. D., Cox N. J., Olkon D. M., Kieffer J. E. et al. 1995 Association of attention-deficit disorder and the dopamine transporter gene. Am. J. Hum. Genet. 56, 993-998.
6. Dorsey E. R., Constantinescu R., Thompson J. P., Biglan K. M., Holloway R. G., Kieburtz K. et al. 2007 Projected number of people with Parkinson disease in the most populous nations, 2005 through 2030. Neurology68, 384-386.
7. Forero D. A., Benitez B., Arboleda G., Yunis J. J., Pardo R. and Arboleda H. 2006a Analysis of functional polymorphisms in three synaptic plasticity-related genes (BDNF, COMT AND UCHL1) in Alzheimer's disease in Colombia. Neurosci. Res. 55, 334-341.
8. Forero D. A, Pinzón J., Arboleda G. H., Yunis J. J., Alvarez C., Cataño N. et al. 2006b Analysis of common polymorphisms in angiotensin-converting enzyme and apolipoprotein E genes and human longevity in Colombia. Arch. Med. Res. 37, 890-894.
9. Forero D. A., Arboleda G., Yunis J. J., Pardo R. and Arboleda H. 2006c Association study of polymorphisms in LRP1, tau and 5-HTT genes and Alzheimer's disease in a sample of Colombian patients. J. Neural. Transm. 113, 1253-1262.
10. Forero D. A., Casadesus G., Perry G. and Arboleda H. 2006d Synaptic dysfunction and oxidative stress in Alzheimer's disease: emerging mechanisms. J. Cell Mol. Med. 10, 796-805.
11. Hahn L. W., Ritchie M. D. and Moore J. H. 2003 Multifactor dimensionality reduction software for detecting gene-gene and geneenvironment interactions. Bioinformatics19, 376-382.
12. Jenkins I. H., Fernandez W., Playford E. D., Lees A. J., Frackowiak R. S., Passingham R. E. et al. 1992 Impaired activation of the supplementary motor area in Parkinson's disease is reversed when akinesia is treated with apomorphine. Ann. Neurol. 32, 749-757.
13. Liao A., Nitsch R. M., Greenberg S. M., Finckh U., Blacker D., Albert M. et al. 1998 Genetic association of an alpha2-macroglobulin (Val1000lle) polymorphism and Alzheimer's disease. Hum. Mol. Genet. 7, 1953-1956.
14. López M., Guerrero J., Yescas P., Boll M. C., Familiar I., Ochoa A. et al. 2007 Apolipoprotein E epsilon4 allele is associated with Parkinson disease risk in a Mexican Mestizo population. Mov. Disorders22, 417-420.
15. Okubadejo N. U. 2008 An analysis of genetic studies of Parkinson's disease in Africa. Parkinsonism Rel. Disord. 14, 177-182.
16. Pradilla A. G., Vesga A. B. and Leon-Sarmiento F. E. 2003 National neuroepidemiological study in Colombia (EPINEURO). Rev. Panam. Salud Publica14, 104-111.
17. Purcell S., Cherny S. S. and Sham P. C. 2003 Genetic power calculator: design of linkage and association genetic mapping studies of complex traits. Bioinformatics19, 149-150.
18. Sole X., Guino E., Valls J., Iniesta R. and Moreno V. 2006 SNPStats: a web tool for the analysis of association studies. Bioinformatics22, 1928-1929.
19. Thomas B. and Beal M. F. 2007 Parkinson's disease. Hum. Mol. Genet. 16, R183-R194.
20. Yunis J. J., Garcia O., Cuervo A. G., Guio E., Pineda C. R. and Yunis E. J. 2005 Population data for PowerPlex 16 in thirteen departments and the capital city of Colombia. J. Forensic Sci. 50, 685-702.