메뉴 건너뛰기




Volumn 51, Issue 10, 2010, Pages 1126-1136

Gadolinium released from MR contrast agents is deposited in brain tumors: In situ demonstration using scanning electron microscopy with energy dispersive X-ray spectroscopy

Author keywords

Complications; MR imaging; Pathology; Tissue characterization

Indexed keywords

ABNORMAL TISSUES; BEFORE AND AFTER; BLOOD-BRAIN BARRIER; BRAIN TUMORS; COMPLICATIONS; CONTRAST-ENHANCED MR; ELECTRONIC RECORDS; ENERGY DISPERSIVE X RAY SPECTROSCOPY; EXACT TESTS; IN-SITU; MR CONTRAST AGENTS; MR IMAGING; MRI CONTRAST AGENTS; RENAL DISEASE; RENAL FAILURE; SCANNING ELECTRONS; SEM/EDS; STATISTICAL SIGNIFICANCE; TISSUE CHARACTERIZATION;

EID: 78349291543     PISSN: 02841851     EISSN: 16000455     Source Type: Journal    
DOI: 10.3109/02841851.2010.515614     Document Type: Article
Times cited : (63)

References (32)
  • 3
    • 0029823540 scopus 로고    scopus 로고
    • Free gadolinium and gadodiamide, a gadolinium chelate used in magnetic resonance imaging: Evaluation of their in vitro effects on human neutrophil viability
    • Behra-Miellet J, Gressier B, Brunet C, Dine T, Luyckx M, Cazin M, et al. Free gadolinium and gadodiamide, a gadolinium chelate used in magnetic resonance imaging: evaluation of their in vitro effects on human neutrophil viability. Methods Find Exp Clin Pharmacol 1996;18:437-42.
    • (1996) Methods Find Exp. Clin. Pharmacol. , vol.18 , pp. 437-442
    • Behra-Miellet, J.1    Gressier, B.2    Brunet, C.3    Dine, T.4    Luyckx, M.5    Cazin, M.6
  • 4
    • 33645289942 scopus 로고    scopus 로고
    • Gadolinium - A specific trigger for the development of nephrogenic fibrosing dermopathy and nephrogenic systemic fibrosis?
    • Grobner T. Gadolinium - a specific trigger for the development of nephrogenic fibrosing dermopathy and nephrogenic systemic fibrosis? Nephrol Dial Transplant 2006;21:1104-8.
    • (2006) Nephrol. Dial Transplant , vol.21 , pp. 1104-1108
    • Grobner, T.1
  • 5
    • 49049083457 scopus 로고    scopus 로고
    • Is NSF only the tip of the "gadolinium toxicity" iceberg?
    • Thomsen HS. Is NSF only the tip of the "gadolinium toxicity" iceberg? J Magn Reson Imaging 2008;28:284-6.
    • (2008) J. Magn. Reson. Imaging , vol.28 , pp. 284-286
    • Thomsen, H.S.1
  • 6
    • 33748049106 scopus 로고    scopus 로고
    • Nephrogenic systemic fibrosis: Suspected causative role of gadodiamide used for contrast-enhanced magnetic resonance imaging
    • Marckmann P, Skov L, Rossen K, Dupont A, Damholt MB, Heaf JG, et al. Nephrogenic systemic fibrosis: suspected causative role of gadodiamide used for contrast-enhanced magnetic resonance imaging. J Am Soc Nephrol 2006;17:2359-62.
    • (2006) J. Am. Soc. Nephrol. , vol.17 , pp. 2359-2362
    • Marckmann, P.1    Skov, L.2    Rossen, K.3    Dupont, A.4    Damholt, M.B.5    Heaf, J.G.6
  • 7
    • 34250165744 scopus 로고    scopus 로고
    • Nephrogenic systemic fibrosis following the administration of extracellular gadolinium based contrast agents: Is the stability of the contrast agent molecule an important factor in the pathogenesis of this condition?
    • Morcos SK. Nephrogenic systemic fibrosis following the administration of extracellular gadolinium based contrast agents: is the stability of the contrast agent molecule an important factor in the pathogenesis of this condition? Br J Radiol 2007;80:73-6.
    • (2007) Br. J. Radiol. , vol.80 , pp. 73-76
    • Morcos, S.K.1
  • 8
    • 70349678871 scopus 로고    scopus 로고
    • Free gadolinium is a likely trigger of nephrogenic systemic fibrosis
    • author reply W355
    • Abraham JL, Edward M. Free gadolinium is a likely trigger of nephrogenic systemic fibrosis. Am J Roentgenol 2009;193: W354; author reply W355.
    • (2009) Am. J. Roentgenol. , vol.193
    • Abraham, J.L.1    Edward, M.2
  • 9
    • 41649098148 scopus 로고    scopus 로고
    • Gadodiamide contrast agent 'activates' fibroblasts: A possible cause of nephrogenic systemic fibrosis
    • Edward M, Quinn JA, Mukherjee S, Jensen MB, Jardine AG, Mark PB, et al. Gadodiamide contrast agent 'activates' fibroblasts: a possible cause of nephrogenic systemic fibrosis. J Pathol 2008;214:584-93.
    • (2008) J. Pathol. , vol.214 , pp. 584-593
    • Edward, M.1    Quinn, J.A.2    Mukherjee, S.3    Jensen, M.B.4    Jardine, A.G.5    Mark, P.B.6
  • 11
    • 0031799353 scopus 로고    scopus 로고
    • Pharmacokinetics of gadodiamide injection in patients with severe renal insufficiency and patients undergoing hemodialysis or continuous ambulatory peritoneal dialysis
    • Joffe P, Thomsen HS, Meusel M. Pharmacokinetics of gadodiamide injection in patients with severe renal insufficiency and patients undergoing hemodialysis or continuous ambulatory peritoneal dialysis. Acad Radiol 1998;5:491-502.
    • (1998) Acad. Radiol. , vol.5 , pp. 491-502
    • Joffe, P.1    Thomsen, H.S.2    Meusel, M.3
  • 12
    • 38149086937 scopus 로고    scopus 로고
    • High prevalence of nephrogenic systemic fibrosis in chronic renal failure patients exposed to gadodiamide, a gadolinium-containing magnetic resonance contrast agent
    • Rydahl C, Thomsen HS, Marckmann P. High prevalence of nephrogenic systemic fibrosis in chronic renal failure patients exposed to gadodiamide, a gadolinium-containing magnetic resonance contrast agent. Invest Radiol 2008;43:141-4.
    • (2008) Invest. Radiol. , vol.43 , pp. 141-144
    • Rydahl, C.1    Thomsen, H.S.2    Marckmann, P.3
  • 13
    • 39049105128 scopus 로고    scopus 로고
    • Gadolinium-induced nephrogenic systemic fibrosis in a patient with an acute and transient kidney injury
    • Kalb RE, Helm TN, Sperry H, Thakral C, Abraham JL, Kanal E. Gadolinium-induced nephrogenic systemic fibrosis in a patient with an acute and transient kidney injury. Br J Dermatol 2008;158:607-10.
    • (2008) Br. J. Dermatol. , vol.158 , pp. 607-610
    • Kalb, R.E.1    Helm, T.N.2    Sperry, H.3    Thakral, C.4    Abraham, J.L.5    Kanal, E.6
  • 14
    • 38349103948 scopus 로고    scopus 로고
    • Dermal inorganic gadolinium concentrations: Evidence for in vivo transmetallation and long-term persistence in nephrogenic systemic fibrosis
    • Abraham JL, Thakral C, Skov L, Rossen K, Marckmann P. Dermal inorganic gadolinium concentrations: evidence for in vivo transmetallation and long-term persistence in nephrogenic systemic fibrosis. Br J Dermatol 2007;158:273-80.
    • (2007) Br. J. Dermatol. , vol.158 , pp. 273-280
    • Abraham, J.L.1    Thakral, C.2    Skov, L.3    Rossen, K.4    Marckmann, P.5
  • 15
    • 35148897393 scopus 로고    scopus 로고
    • Automated scanning electron microscopy and x-ray microanalysis for in situ quantification of Gadolinium deposits in skin
    • Thakral C, Abraham JL. Automated scanning electron microscopy and x-ray microanalysis for in situ quantification of Gadolinium deposits in skin. J Electron Microsc (Tokyo) 2007;56:181-7.
    • (2007) J. Electron. Microsc. (Tokyo) , vol.56 , pp. 181-187
    • Thakral, C.1    Abraham, J.L.2
  • 16
    • 35148816595 scopus 로고    scopus 로고
    • Long-term retention of gadolinium in tissues from nephrogenic systemic fibrosis patient after multiple gadolinium-enhanced MRI scans: Case report and implications
    • Thakral C, Alhariri J, Abraham JL. Long-term retention of gadolinium in tissues from nephrogenic systemic fibrosis patient after multiple gadolinium-enhanced MRI scans: case report and implications. Contrast Media Mol Imaging 2007;2:199-205.
    • (2007) Contrast Media Mol. Imaging , vol.2 , pp. 199-205
    • Thakral, C.1    Alhariri, J.2    Abraham, J.L.3
  • 17
    • 33845702376 scopus 로고    scopus 로고
    • Gadolinium deposition in nephrogenic fibrosing dermopathy
    • Boyd AS, Zic JA, Abraham JL. Gadolinium deposition in nephrogenic fibrosing dermopathy. J Am Acad Dermatol 2007;56:27-30.
    • (2007) J. Am. Acad. Dermatol. , vol.56 , pp. 27-30
    • Boyd, A.S.1    Zic, J.A.2    Abraham, J.L.3
  • 18
    • 78249234736 scopus 로고    scopus 로고
    • Synchrotron X-ray analyses demonstrate phosphate-bound gadolinium in skin in nephrogenic systemic fibrosis
    • Jun. 19 E-pub ahead of print
    • George SJ, Webb SM, Abraham JL, Cramer S P. Synchrotron X-ray analyses demonstrate phosphate-bound gadolinium in skin in nephrogenic systemic fibrosis. Br J Dermatol 2010 Jun. 19 [E-pub ahead of print].
    • (2010) Br. J. Dermatol.
    • George, S.J.1    Webb, S.M.2    Abraham, J.L.3    Cramer, S.P.4
  • 19
    • 33845991496 scopus 로고    scopus 로고
    • Contrast-enhanced magnetic resonance imaging of central nervous system tumors: Agents, mechanisms, and applications
    • Essig M, Weber MA, von Tengg-Kobligk H, Knopp M V, Yuh WT, Giesel FL. Contrast-enhanced magnetic resonance imaging of central nervous system tumors: agents, mechanisms, and applications. Top Magn Reson Imaging 2006;17:89-106.
    • (2006) Top Magn Reson Imaging , vol.17 , pp. 89-106
    • Essig, M.1    Weber, M.A.2    Von Tengg-Kobligk, H.3    Knopp, M.V.4    Yuh, W.T.5    Giesel, F.L.6
  • 20
    • 78349278323 scopus 로고
    • SAS Institute, Version 7
    • SAS Institute. JMP. 1989-2007; Version 7.
    • (1989) JMP
  • 21
    • 10744219916 scopus 로고    scopus 로고
    • Silencing of phosphonate-gadolinium magnetic resonance imaging contrast by hydroxyapatite binding
    • Alves FC, Donato P, Sherry AD, Zaheer A, Zhang S, Lubag AJ, et al. Silencing of phosphonate-gadolinium magnetic resonance imaging contrast by hydroxyapatite binding. Invest Radiol 2003;38:750-60.
    • (2003) Invest. Radiol. , vol.38 , pp. 750-760
    • Alves, F.C.1    Donato, P.2    Sherry, A.D.3    Zaheer, A.4    Zhang, S.5    Lubag, A.J.6
  • 22
    • 33751067666 scopus 로고    scopus 로고
    • Clinical and biological consequences of transmetallation induced by contrast agents for magnetic resonance imaging: A review
    • Idee JM, Port M, Raynal I, Schaefer M, Le Greneur S, Corot C. Clinical and biological consequences of transmetallation induced by contrast agents for magnetic resonance imaging: a review. Fundam Clin Pharmacol 2006;20:563-76.
    • (2006) Fundam Clin. Pharmacol. , vol.20 , pp. 563-576
    • Idee, J.M.1    Port, M.2    Raynal, I.3    Schaefer, M.4    Le Greneur, S.5    Corot, C.6
  • 23
    • 56449105818 scopus 로고    scopus 로고
    • SIMS imaging of gadolinium isotopes in tissue from nephrogenic systemic fibrosis patients: Release of free Gd from magnetic resonance imaging contrast agents
    • Abraham JL, Chandra S, Thakral C, Abraham JM. SIMS imaging of gadolinium isotopes in tissue from nephrogenic systemic fibrosis patients: release of free Gd from magnetic resonance imaging contrast agents. App Surf Sci 2008;255:1181-4.
    • (2008) App Surf Sci. , vol.255 , pp. 1181-1184
    • Abraham, J.L.1    Chandra, S.2    Thakral, C.3    Abraham, J.M.4
  • 24
    • 52049085751 scopus 로고    scopus 로고
    • Preclinical investigation to compare different gadolinium-based contrast agents regarding their propensity to release gadolinium in vivo and to trigger nephrogenic systemic fibrosis-like lesions
    • Sieber MA, Lengsfeld P, Frenzel T, Golfier S, Schmitt-Willich H, Siegmund F, et al. Preclinical investigation to compare different gadolinium-based contrast agents regarding their propensity to release gadolinium in vivo and to trigger nephrogenic systemic fibrosis-like lesions. Eur Radiol 2008;18:2164-73.
    • (2008) Eur. Radiol. , vol.18 , pp. 2164-2173
    • Sieber, M.A.1    Lengsfeld, P.2    Frenzel, T.3    Golfier, S.4    Schmitt-Willich, H.5    Siegmund, F.6
  • 25
    • 33745910870 scopus 로고    scopus 로고
    • Comparison of Gd (DTPA-BMA) (Omniscan) versus Gd (HP-DO3A) (Pro-hance) relative to gadolinium retention in human bone tissue by inductively coupled plasma mass spectroscopy
    • White G W, Gibby WA, Tweedle MF. Comparison of Gd (DTPA-BMA) (Omniscan) versus Gd (HP-DO3A) (Pro-Hance) relative to gadolinium retention in human bone tissue by inductively coupled plasma mass spectroscopy. Invest Radiol 2006;41:272-8.
    • (2006) Invest. Radiol. , vol.41 , pp. 272-278
    • White, G.W.1    Gibby, W.A.2    Tweedle, M.F.3
  • 27
    • 0032231923 scopus 로고    scopus 로고
    • Neurotoxic potential of gadodiamide after injection into the lateral cerebral ventricle of rats
    • Ray DE, Holton JL, Nolan CC, Cavanagh JB, Harpur ES. Neurotoxic potential of gadodiamide after injection into the lateral cerebral ventricle of rats. Am J Neuroradiol 1998;19:1455-62.
    • (1998) Am. J. Neuroradiol. , vol.19 , pp. 1455-1462
    • Ray, D.E.1    Holton, J.L.2    Nolan, C.C.3    Cavanagh, J.B.4    Harpur, E.S.5
  • 28
    • 0030042252 scopus 로고    scopus 로고
    • Neurotoxic effects of gadopentetate dimeglumine: Behavioral disturbance and morphology after intracerebroventricular injection in rats
    • Ray DE, Cavanagh JB, Nolan CC, Williams SC. Neurotoxic effects of gadopentetate dimeglumine: behavioral disturbance and morphology after intracerebroventricular injection in rats. Am J Neuroradiol 1996;17:365-73.
    • (1996) Am. J. Neuroradiol. , vol.17 , pp. 365-373
    • Ray, D.E.1    Cavanagh, J.B.2    Nolan, C.C.3    Williams, S.C.4
  • 30
    • 0026043660 scopus 로고
    • Effects of gadopentetate dimeglumine administration after osmotic blood-brain barrier disruption: Toxicity and MR imaging findings
    • Roman-Goldstein SM, Barnett PA, McCormick CI, Ball MJ, Ramsey F, Neuwelt EA. Effects of gadopentetate dimeglumine administration after osmotic blood-brain barrier disruption: toxicity and MR imaging findings. Am J Neuroradiol 1991;12:885-90.
    • (1991) Am. J. Neuroradiol. , vol.12 , pp. 885-890
    • Roman-Goldstein, S.M.1    Barnett, P.A.2    McCormick, C.I.3    Ball, M.J.4    Ramsey, F.5    Neuwelt, E.A.6
  • 32


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.