Distribution of cardiac iron measured by magnetic resonance imaging (MRI)-R*2

Journal of Magnetic Resonance Imaging

Volumn 32, Issue 5, 2010, Pages 1104-1109

  Yamamura, Jin ^a   Grosse, Regine ^a   Graessner, Joachim ^b   Janka, Gritta E ^a   Adam, Gerhard ^a   Fischer, Roland ^a,c  

^a UNIVERSITY MEDICAL CENTER HAMBURG EPPENDORF   (Germany)

^b SIEMENS AG   (Germany)

^c CHILDREN S HOSPITAL OAKLAND   (United States)

Author keywords

boundary effect; iron; myocardium; R2; relaxation rate

Indexed keywords

IRON;

ADOLESCENT; ADULT; AGED; ARTICLE; BLOOD; CHILD; CLINICAL ARTICLE; ELECTROCARDIOGRAM; EPICARDIUM; HEART; HUMAN; IRON METABOLISM; IRON OVERLOAD; LIVER; LUNG PARENCHYMA; NUCLEAR MAGNETIC RESONANCE IMAGING; PRIORITY JOURNAL; SCHOOL CHILD; THALASSEMIA MAJOR;

ADOLESCENT; ADULT; AGED; BETA-THALASSEMIA; CHILD; HUMANS; IRON; IRON OVERLOAD; MAGNETIC RESONANCE IMAGING; MYOCARDIUM; YOUNG ADULT;

EID: 78349285593     PISSN: 10531807     EISSN: 15222586     Source Type: Journal    
DOI: 10.1002/jmri.22364     Document Type: Article

References (30)

1. Cohen AR, Galanello R, Pennell DJ, Cunningham MJ, Vichinsky E., Thalassemia. Hematol Am Soc Hematol Educ Program 2004: 14-34.
2. Borgna-Pignatti C, Cappellini MD, De Stefano P, et al. Survival and complications in thalassemia. Ann N Y Acad Sci 2005; 1054: 40-47.
3. Borgna-Pignatti C, Cappellini MD, De Stefano P, et al. Cardiac morbidity and mortality in deferoxamine- or deferiprone-treated patients with thalassemia major. Blood 2006; 107: 3733-3737.
4. Borgna-Pignatti C, Rugolotto S, De Stefano P, et al. Survival and complications in patients with thalassemia major treated with transfusion and deferoxamine. Haematologica 2004; 89: 1187-1193.
5. Olivieri NF, Brittenham GM., Iron-chelating therapy and the treatment of thalassemia. Blood 1997; 89: 739-761.
6. Fischer R, Tiemann CD, Engelhardt R, et al. Assessment of iron stores in children with transfusion siderosis by biomagnetic liver susceptometry. Am J Hematol 1999; 60: 289-299.
7. Richardson ME, Matthews RN, Alison JF, et al. Prevention of heart disease by subcutaneous desferrioxamine in patients with thalassaemia major. Aust N Z J Med 1993; 23: 656-661.
8. Gotsis E, Farmaki K, Toulas P, Kalliou V, Deftereos S, Aessopos A,. Myocardium and liver iron overload in beta-thalassaemia patients by quantitative magnetic-resonance-imaging. In: Proc 8th Int Conf Thalassaemia Haemoglobinopathies 2001: 150.
9. Capra M, Di Gregorio F, Fischer R, Magnano C, Meo A, Nielsen P,. Liver iron stores and cardiac function in β-thalassemia. In: Proc 8th Int Conf Thalassaemia Haemoglobinopathies 2001: 162.
10. Anderson LJ, Holden S, Davis B, et al. Cardiovascular T2-star (T2*) magnetic resonance for the early diagnosis of myocardial iron overload. Eur Heart J 2001; 22: 2171-2179.
11. Anderson LJ, Wonke B, Prescott E, Holden S, Walker JM, Pennell DJ., Comparison of effects of oral deferiprone and subcutaneous desferrioxamine on myocardial iron concentrations and ventricular function in beta-thalassaemia. Lancet 2002; 360: 516-520.
12. Buja LM, Roberts WC., Iron in the heart. Etiology and clinical significance. Am J Med 1971; 51: 209-221.
13. Barosi G, Arbustini E, Gavazzi A, Grasso M, Pucci A., Myocardial iron grading by endomyocardial biopsy. A clinico-pathologic study on iron overloaded patients. Eur J Haematol 1989; 42: 382-388.
14. Lombardo T, Tamburino C, Bartoloni G, et al. Cardiac iron overload in thalassemic patients: an endomyocardial biopsy study. Ann Hematol 1995; 71: 135-141.
15. Wielopolski L, Zaino EC., Noninvasive in-vivo measurement of hepatic and cardiac iron. J Nucl Med 1992; 33: 1278-1282.
16. Zaino EC., Cardiac siderosis in thalassemia major. NY State J Med 1985; 85: 513-515.
17. Johnston DL, Rice L, Vick GW 3rd, Hedrick TD, Rokey R., Assessment of tissue iron overload by nuclear magnetic resonance imaging. Am J Med 1989; 87: 40-47. (Pubitemid 19179408)
18. Jensen PD, Jensen FT, Christensen T, Heickendorff L, Jensen LG, Ellegaard J., Indirect evidence for the potential ability of magnetic resonance imaging to evaluate the myocardial iron content in patients with transfusional iron overload. Magma 2001; 12: 153-166.
19. Hazirolan T, Akpinar B, Unal S, Gumruk F, Haliloglu M, Alibek S., Value of dual energy computed tomography for detection of myocardial iron deposition in thalassaemia patients: initial experience. Eur J Radiol 2008; 68: 442-445.
20. Pepe A, Positano V, Santarelli MF, et al. Multislice multiecho T2* cardiovascular magnetic resonance for detection of the heterogeneous distribution of myocardial iron overload. J Magn Reson Imaging 2006; 23: 662-668.
21. Ghugre NR, Enriquez CM, Coates TD, Nelson MD Jr, Wood JC., Improved R2* measurements in myocardial iron overload. J Magn Reson Imaging 2006; 23: 9-16.
22. Clark PR, St Pierre TG., Quantitative mapping of transverse relaxivity (1/T(2)) in hepatic iron overload: a single spin-echo imaging methodology. Magn Reson Imaging 2000; 18: 431-438.
23. Olson LJ, Edwards WD, McCall JT, Ilstrup DM, Gersh BJ., Cardiac iron deposition in idiopathic hemochromatosis: histologic and analytic assessment of 14 hearts from autopsy. J Am Coll Cardiol 1987; 10: 1239-1243.
24. Reeder SB, Faranesh AZ, Boxerman JL, McVeigh ER., In vivo measurement of T*2 and field inhomogeneity maps in the human heart at 1.5 T. Magn Reson Med 1998; 39: 988-998.
25. Positano V, Pepe A, Santarelli MF, et al. Standardized T2* map of normal human heart in vivo to correct T2* segmental artefacts. NMR Biomed 2007; 20: 578-590.
26. Positano V, Pepe A, Santarelli MF, et al. Multislice multiecho T2* cardiac magnetic resonance for the detection of heterogeneous myocardial iron distribution in thalassaemia patients. NMR Biomed 2009; 22: 707-715.
27. Wang ZJ, Fischer R, Chu Z, et al. Assessment of cardiac iron by MRI susceptometry and R2* in patients with thalassemia. Magn Reson Imaging 2010; 28: 363-371.
28. Wehrli FW, Ford JC, Attie M, Kressel HY, Kaplan FS., Trabecular structure: preliminary application of MR interferometry. Radiology 1991; 179: 615-621.
29. O'Regan DP, Callaghan MF, Fitzpatrick J, Naoumova RP, Hajnal JV, Schmitz SA., Cardiac T2* and lipid measurement at 3.0 T-initial experience. Eur Radiol 2008; 18: 800-805.
30. Ghugre NR, Enriquez CM, Gonzalez I, Nelson MD Jr, Coates TD, Wood JC., MRI detects myocardial iron in the human heart. Magn Reson Med 2006; 56: 681-686.