Neopterin and atherosclerotic plaque instability in coronary and carotid arteries

Journal of Atherosclerosis and Thrombosis

Volumn 17, Issue 11, 2010, Pages 1115-1121

  Sugioka, Kenichi ^a   Naruko, Takahiko ^b   Matsumura, Yoshiki ^a   Shirai, Nobuyuki ^a   Hozumi, Takeshi ^a   Yoshiyama, Minoru ^a   Ueda, Makiko ^a  

^a OSAKA CITY UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^b OSAKA CITY GENERAL HOSPITAL   (Japan)

Author keywords

Carotid artery; Complex plaques; Coronary artery; Neopterin

Indexed keywords

NEOPTERIN;

ANGIOCARDIOGRAPHY; ATHERECTOMY; ATHEROSCLEROTIC PLAQUE; CAROTID ATHEROSCLEROSIS; CAROTID ENDARTERECTOMY; CORONARY ARTERY ATHEROSCLEROSIS; DISEASE ASSOCIATION; HUMAN; IMMUNOHISTOCHEMISTRY; INFLAMMATION; MACROPHAGE; PATHOGENESIS; PREVALENCE; PROGNOSIS; PROTEIN LOCALIZATION; PROTEIN SYNTHESIS; REVIEW; STABLE ANGINA PECTORIS; UNSTABLE ANGINA PECTORIS;

EID: 78349267306     PISSN: 13403478     EISSN: 18803873     Source Type: Journal    
DOI: 10.5551/jat.4606     Document Type: Review

References (40)

1. Ross R: Atherosclerosis: an inflammatory disease. N Engl JMed, 1999; 340: 115-126
2. Libby P, Ridker PM, Maseri A: Inflammation and Atherosclerosis. Circulation, 2002; 105: 1135-1143
3. Gieseg SP, Crone EM, Flavall EA, Amit Z: Potential to inhibit growth of atherosclerotic plaque development through modulation of macrophage neopterin/7,8-dihy-droneopterin synthesis. Br J Pharmacol, 2008; 153: 627-635
4. Huber C, Batchelor JR, Fuchs D, Hausen A, Lang A, Niederwieser D, Reibnegger G, Swetly P, Troppmair J, Wachter H: Immune response-associated production of neopterin. Release from macrophages primarily under control of interferongamma. J Exp Med, 1984; 160: 310-316
5. Fuchs D, Weiss G, Wachter H: Neopterin, biochemistry and clinical use as a marker for cellular immune reactions. Int Arch Allergy Immunol, 1993; 101: 1-6
6. Gupta S, Fredericks S, Schwartzman RA, Holt DW, Kaski JC: Serum neopterin in acute coronary syndromes. Lancet, 1997; 349: 1252-1253
7. Schumacher M, Halwachs G, Tatzber F, Fruhwald FM, Zweiker R, Watzinger N, Eber B, Wilders-Truschnig M, Esterbauer H, Klein W Increased neopterin in patients with chronic and acute coronary syndromes. J Am Coll Cardiol, 1997; 30: 703-707
8. Garcia-Moll X, Coccolo F, Cole D, Kaski JC: Serum neopterin and complex stenosis morphology in patients with unstable angina. J Am Coll Cardiol, 2000; 35: 956-962
9. Avanzas P, Arroyo-Espliguero R, Cosin-Sales J, Aldama G, Pizzi C, Quiles J, Kaski JC: Markers of inflammation and multiple complex stenoses (pancoronary plaque vulnerability) in patients with non-ST segment elevation acute coronary syndromes. Heart, 2004; 90: 847-852
10. Zouridakis E, Avanzas P, Arroyo-Espliguero R, Fredericks S, Kaski JC: Markers of inflammation and rapid coronary artery disease progression in patients with stable angina pectoris. Circulation, 2004; 110: 1747-1753
11. Adachi T, Naruko T, Itoh A, Komatsu R, Abe Y, Shirai N, Yamashita H, Ehara S, Nakagawa M, Kitabayashi C, Ikura Y, Ohsawa M, Yoshiyama M, Haze K, Ueda M: Neopterin is associated with plaque inflammation and destabilisation in human coronary atherosclerotic lesions. Heart, 2007; 93: 1537-1541
12. Garcia-Moll X, Cole D, Zouridakis E, Kaski JC: Increased serum neopterin: a marker of coronary artery disease activity in women. Heart, 2000; 83: 346-350
13. Van Haelst PL, Liem A, Van Boven AD, Veeger NJ, Van Veldhuisen DJ, Tervaert JWC, Gans RO, Zijlstraet F: Usefulness of elevated neopterin and C-reactive protein levels in predicting cardiovascular events in patients with non-Q-wave myocardial infarction. Am J Cardiol, 2003; 92: 1201-1203
14. Avanzas P, Arroyo-Espliguero R, Quiles J, Roy D, Kaski JC: Elevated serum neopterin predicts future adverse cardiac events in patients with chronic stable angina pectoris. Eur Heart J, 2005; 26: 457-463
15. Ray KK, Morrow DA, Sabatine MS, Shui A, Rifai N, Cannon CP, Braunwald E: Long-term prognostic value of neopterin: a novel marker of monocyte activation in patients with acute coronary syndrome. Circulation, 2007; 115:3071-3078
16. Kaski JC, Consuegra-Sanchez L, Fernandez-Berges DJ, Cruz-Fernandez JM, Garcia-Moll X, Marrugat J, Mostaza J, Toro-Cebada R, Gonzalez-Juanatey JR, Guzman-Martinez G; SIESTA Investigators: Elevated serum neopterin levels and adverse cardiac events at 6 months follow-up in Mediterranean patients with non-ST-segment elevation acute coronary syndrome. Atherosclerosis, 2008; 201: 176-183
17. Vengen IT, Dale AC, Wiseth R, Midthjell K, Videm V: Neopterin predicts the risk for fatal ischemic heart disease in type 2 diabetes mellitus. Long-term follow-up of the HUNT 1 study. Atherosclerosis, 2009; 207: 239-244
18. Sugioka K, Naruko T, Hozumi T, Nakagawa M, Kitabayashi C, Ikura Y, Shirai N, Matsumura Y, Ehara S, Ujino K, Itoh A, Haze K, Becker AE, Yoshiyama M, Ueda M: Elevated levels of neopterin are associated with carotid plaques with complex morphology in patients with stable angina pectoris. Atherosclerosis, 2010; 208: 524-530
19. Maggi E, Parronchi P, Manetti R, Simonelli C, Piccinni MP, Rugiu FS, De Carli M, Ricci M, Romagnani S: Reciprocal regulatory role of IFN-y and IL-4 on the in vitro development of human Thl and Th2 clones. J Immunol, 1992; 148: 2142-2148
20. Widner B, Mayr C, Wirleitner B, Fuchs D: Oxidation of 7,8-dihydroneopterin by hypochlorous acid yields neopterin. Biochem Biophys Res Commun, 2000; 275: 307-311
21. Weiss G, Fuchs D, Hausen A, Reibnegger G, Werner ER, Werner-Felmayer G, Semenitz E, Dierich MP, Wachter H: Neopterin modulates toxicity mediated by reactive oxygen and chloride species. FEBS Lett, 1993; 321: 89-92
22. Murr C, Fuchs D, Gossler W, Hausen A, Reibnegger G, Werner ER, Werner-Felmayer G, Esterbauer H, Wachter H: Enhancement of hydrogen peroxide-induced luminol-dependent chemiluminescence by neopterin depends on the presence of iron chelator complexes. FEBS Lett, 1994; 338: 223-226
23. Fuchs D, Hausen A, Reibnegger G, Werner ER, Dierich MP, Wachter H: Neopterin as a marker for activated cell-mediated immunity: application in HIV infection. Immunol Today, 1988; 5: 150-155
24. Reibnegger G, Egg D, Fuchs D, Giinther R, Hausen A, Werner ER, Wachter H: Urinary neopterin reflects clinical activity in patients with rheumatoid arthritis. Arthritis Rheum, 1986; 29: 1063-1070
25. Murr C, Fuith LC, Widner B, Wirleitner B, Baier-Bit-terlich G, Fuchs D: Increased neopterin concentrations in patients with cancer: indicator of oxidative stress? Anti-cancer Res, 1999; 19: 1721-1728
26. Margreiter R, Fuchs D, Hausen A, Huber C, Reibnegger G, Spielberger M, Wachter H: Neopterin as a new bio-marker for the diagnosis of allograft rejection. Experience based upon evaluation of 100 consecutive cases. Transplant, 1983; 36: 650-653
27. Ehara S, Ueda M, Naruko T, Haze K, Itoh A, Otsuka M, Komatsu R, Matsuo T, Itabe H, Takano T, Tsukamoto Y, Yoshiyama M, Takeuchi K, Yoshikawa J, Becker AE: Elevated levels of oxidized low density lipoprotein show a positive relationship with the severity of acute coronary syndromes. Circulation, 2001; 103: 1955-1960
28. Naruko T, Ueda M, Haze K, van der Wal AC, van der Loos CM, Itoh A, Komatsu R, Ikura Y, Ogami M, Shi-mada Y, Ehara S, Yoshiyama M, Takeuchi K, Yoshikawa J, Becker AE: Neutrophil infiltration of culprit lesions in acute coronary syndromes. Circulation, 2002; 106: 2894-2900
29. Bamford J, Sandercock P, Dennis M, Burn J, Warlow C: Classification and natural history of clinically identifiable subtypes of cerebral infarction. Lancet, 1991; 337: 1521-1526
30. Sugioka K, Hozumi T, Iwata S, Oe H, Okuyama T, Shirai N, Yamashita H, Ehara S, Kataoka T, Yoshikawa J, Ueda M, Yoshiyama M: Morphological but not functional changes of the carotid artery are associated with the extent of coronary artery disease in patients with preserved left ventricular function. Stroke, 2008; 39: 1597-1599
31. Handa N, Matsumoto M, Maeda H, Hougaku H, Kamada T: Ischemic stroke events and carotid atherosclerosis. Results of the Osaka follow-up Study for ultraso-nographic Assessment of Carotid Atherosclerosis (the OSACA study). Stroke, 1995; 26: 1781-1786
32. Prabhakaran S, Rundek T, Ramas R, Elkind MS, Paik MC, Boden-Albala B, Sacco RL: Carotid plaque surface irregularity predicts ischemic stroke. The Northern Manhattan Study. Stroke, 2006; 37: 2696-2701
33. Rundek T: Beyond percent stenosis: carotid plaque surface irregularity and risk of stroke. Int J Stroke, 2007; 2: 169-171
34. Sugioka K, Hozumi T, Sciacca RR, Miyake Y, Titova I, Gaspard G, Sacco RL, Homma S, Di TuUio MR: Impact of aortic stiffness on ischemic stroke in elderly patients. Stroke, 2002; 33: 2077-2081
35. Di TuUio MR, Sacco RL, Savoia MT, Sciacca RR, Homma S: Aortic atheroma morphology and the risk of ischemic stroke in a multiethnic population. Am Heart J, 2000; 139: 329-336
36. Di TuUio MR, Russo C, Jin Z, Sacco RL, Mohr JP, Homma S: Aortic arch plaques and risk of recurrent stroke and death. Circulation, 2009; 119: 2376-2382
37. Corrado E, Rizzo M, Coppola G, Fattouch K, Novo G, Marturana I, Ferrara F, Novo S: An update on the role of markers of inflammation in atherosclerosis. J Atheroscler Thromb, 2010; 17: 1-11
38. Lombardo A, Biasucci LM, Lanza GA, Coli S, Silvestri P, Cianflone D, Liuzzo G, Burzotta F, Crea F, Maseri A: Inflammation as a possible link between coronary and carotid plaque instability. Circulation, 2004; 109: 3158-3163
39. Weiss G, Willeit J, Kiechl S, Fuchs D, Jarosch E, Ober-hollenzer F, Reibnegger G, Tilz GP, Gerstenbrand F, Wachter H: Increased concentrations of neopterin in carotid atherosclerosis. Atherosclerosis, 1994; 106: 263-271
40. Kaplan RC, McGinn AP, Baird AE, Hendrix SL, Kooper-berg C, Lynch J, Rosenbaum DM, Johnson KC, Strickler HD, Wassertheil-Smoller S: Inflammation and hemostasis biomarkers for predicting stroke in postmenopausal women: the Women's Health Initiative Observational Study. J Stroke Cerebrovasc Dis, 2008; 17: 344-355