The differential effect of gastroesophageal reflux disease on mechanostimulation and chemostimulation of the laryngopharynx

Chest

Volumn 138, Issue 5, 2010, Pages 1180-1185

  Phua, Sin Yong ^a   McGarvey, Lorcan ^b   Ngu, Meng ^a   Ing, Alvin ^a  

^a ANZAC Research Institute   (Australia)

^b QUEEN'S UNIVERSITY BELFAST   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

HYDROCHLORIC ACID; SODIUM CHLORIDE;

ADULT; AGED; ARTICLE; ATMOSPHERIC PRESSURE; CLINICAL ARTICLE; COMPARATIVE STUDY; CONTROLLED STUDY; CORRELATION ANALYSIS; DIFFERENTIAL THRESHOLD; FEMALE; GASTROESOPHAGEAL REFLUX; HUMAN; HYPOPHARYNX; MALE; MECHANICAL STIMULATION; PRIORITY JOURNAL; STIMULATION;

EID: 78349261934     PISSN: 00123692     EISSN: 19313543     Source Type: Journal    
DOI: 10.1378/chest.09-2387     Document Type: Article

References (24)

1. Aviv JE, Martin JH, Sacco RL, et al. Supraglottic and pharyngeal sensory abnormalities in stroke patients with dysphagia. Ann Otol Rhinol Laryngol. 1996;105(2):92-97.
2. Shaker R, Milbrath M, Ren J, et al. Esophagopharyngeal distribution of refluxed gastric acid in patients with reflux laryngitis. Gastroenterology. 1995;109(5):1575-1582.
3. Aviv JE, Liu H, Parides M, Kaplan ST, Close LG. Laryngopharyngeal sensory deficits in patients with laryngopharyngeal reflux and dysphagia. Ann Otol Rhinol Laryngol. 2000; 109(11):1000-1006.
4. Tobin RW, Pope CE II, Pellegrini CA, Emond MJ, Sillery J, Raghu G. Increased prevalence of gastroesophageal reflux in patients with idiopathic pulmonary fibrosis. Am J Respir Crit Care Med. 1998;158(6):1804-1808.
5. Harding SM, Richter JE. The role of gastroesophageal reflux in chronic cough and asthma. Chest. 1997;111(5):1389-1402.
6. Ing AJ. Interstitial lung disease and gastroesophageal reflux. Am J Med. 2001;111(Suppl 8A):41S-44S.
7. Phua SY, McGarvey LP, Ngu MC, Ing AJ. Patients with gastrooesophageal reflux disease and cough have impaired laryngopharyngeal mechanosensitivity. Thorax. 2005;60(6):488-491.
8. Widdicombe J. Airway receptors. Respir Physiol. 2001;125 (1-2):3-15.
9. Sant'Ambrogio G, Widdicombe J. Reflexes from airway rapidly adapting receptors. Respir Physiol. 2001;125(1-2):33-45.
10. Kajii Y, Shingai T, Kitagawa J, et al. Sour taste stimulation facilitates reflex swallowing from the pharynx and larynx in the rat. Physiol Behav. 2002;77(2-3):321-325.
11. Kovar I, Selstam U, Catterton WZ, Stahlman MT, Sundell HW. Laryngeal chemoreflex in newborn lambs: respiratory and swallowing response to salts, acids, and sugars. Pediatr Res. 1979;13(10):1144-1149.
12. Johnson LF, DeMeester TR. Development of the 24-hour intraesophageal pH monitoring composite scoring system. J Clin Gastroenterol. 1986;8(Suppl 1):52-58.
13. Savary M, Miller G. The Oesophagus. Handbook and Atlas of Endoscopy. Solothrun, Switzerland: Verlag Gassman;1978.
14. Hanamori T, Kunitake T, Kato K, Kannan H. Neurons in the posterior insular cortex are responsive to gustatory stimulation of the pharyngolarynx, baroreceptor and chemoreceptor stimulation, and tail pinch in rats. Brain Res. 1998;785(1):97-106.
15. Yoshida Y, Tanaka Y, Hirano M, Nakashima T. Sensory innervation of the pharynx and larynx. Am J Med. 2000;108(Suppl 4a): 51S-61S.
16. Bradley RM. Sensory receptors of the larynx. Am J Med. 2000;108(Suppl 4a):47S-50S.
17. Sant'Ambrogio G, Brambilla-Sant'Ambrogio F, Mathew OP. Effect of cold air on laryngeal mechanoreceptors in the dog. Respir Physiol. 1986;64(1):45-56.
18. Shephard KL, Rahmoune H. Evaporation-induced changes in airway surface liquid on an isolated guinea pig trachea. J Appl Physiol. 1994;76(3):1156-1165.
19. Helm JF, Dodds WJ, Hogan WJ. Salivary response to esophageal acid in normal subjects and patients with reflux esophagitis. Gastroenterology. 1987;93(6):1393-1397.
20. Siddiqui MA, Johnston BT, Leite LP, Katzka DA, Castell DO. Sensitization of esophageal mucosa by prior acid infusion: effect of decreasing intervals between infusions. Am J Gastroenterol. 1996;91(9):1745-1748.
21. Partosoedarso ER, Blackshaw LA. Vagal efferent fibre responses to gastric and oesophageal mechanical and chemical stimuli in the ferret. J Auton Nerv Syst. 1997;66(3):169-178.
22. Fass R, Naliboff B, Higa L, et al. Differential effect of longterm esophageal acid exposure on mechanosensitivity and chemosensitivity in humans. Gastroenterology. 1998;115(6): 1363-1373.
23. Davis PJ, Nail BS. The sensitivity of laryngeal epithelial receptors to static and dynamic forms of mechanical stimulation. In: Fujimura O, ed. Vocal Physiology: Vocal Production, Mechanisms and Functions. New York, NY: Raven Press;1988: 1-23.
24. Suwanprathes P, Ngu M, Ing A, Hunt G, Seow F. c-Fos immunoreactivity in the brain after esophageal acid stimulation. Am J Med. 2003;115(Suppl 3A):31S-38S.