Patients with gastro-oesophageal reflux disease and cough have impaired laryngopharyngeal mechanosensitivity

Thorax

Volumn 60, Issue 6, 2005, Pages 488-491

  Phua, S Y ^b   McGarvey, L P A ^a   Ngu, M C ^c   Ing, A J ^b  

^a QUEEN'S UNIVERSITY BELFAST   (United Kingdom)

^b Respiratory Investigation Unit   (Australia)

^c Department of Microbiology and Infectious Diseases   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

HYDROCHLORIC ACID; SODIUM CHLORIDE;

ADULT; AGED; ANESTHESIA; ARTICLE; ASPIRATION PNEUMONIA; ATMOSPHERIC PRESSURE; CHEMOSENSITIVITY; CLINICAL ARTICLE; CONTROLLED STUDY; COUGHING; FEMALE; FIBERSCOPE ENDOSCOPY; GASTROESOPHAGEAL REFLUX; HIGH RISK PATIENT; HUMAN; INFUSION; LARYNGEAL ADDUCTOR REFLEX; LARYNGOPHARYNGEAL MECHANOSENSITIVITY; MALE; PARAMETER; PRIORITY JOURNAL; REFLEX; RISK ASSESSMENT; SCREENING TEST; SENSORY DYSFUNCTION; STROKE; TECHNIQUE;

ADULT; AGED; CASE-CONTROL STUDIES; CHRONIC DISEASE; COUGH; DEGLUTITION; ENDOSCOPY; FEMALE; FIBER OPTICS; GASTROESOPHAGEAL REFLUX; HUMANS; HYDROCHLORIC ACID; LARYNGEAL DISEASES; MALE; MIDDLE AGED; PHARYNGEAL DISEASES; SENSORY THRESHOLDS; SODIUM CHLORIDE;

EID: 20444443998     PISSN: 00406376     EISSN: None     Source Type: Journal    
DOI: 10.1136/thx.2004.033894     Document Type: Article

References (24)

1. Aviv JE, Martin JH, Sacco RL, et al. Supraglottic and pharyngeal sensory abnormalities in stroke patients with dysphagia. Ann Otol Rhinol Laryngol 1996;105:92-7.
2. Shaker R, Milbrath M, Ren J, et al. Esophagopharyngeal distribution of refluxed gastric acid in patients with reflux laryngitis. Gastroenterology 1995;109:1575-82.
3. Aviv JE, Sacco RL, Thomson J, et al. Silent laryngopharyngeal sensory deficits after stroke. Ann Otol Rhinol Laryngol 1997;106:87-93.
4. Aviv JE, Liu H, Parides M, et al. Laryngopharyngeal sensory deficits in patients with laryngopharyngeal reflux and dysphagia. Ann Otol Rhinol Laryngol 2000;109:1000-6.
5. Harding SM, Richter JE. The role of gastroesophageal reflux in chronic cough and asthma. Chest 1997;111:1389-402.
6. Ing AJ. Interstitial lung disease and gastroesophageal reflux. Am J Med 2001;111(Suppl 8A):41-4S.
7. Ulualp SO, Toohill RJ, Kern M, et al. Pharyngo-UES contractile reflex in patients with posterior laryngitis. Laryngoscope 1998;108:1354-7.
8. Shaker R, Hogan WJ. Reflex-mediated enhancement of airway protective mechanisms. Am J Med 2000;108(Suppl 4a):8-14S.
9. Kidd D, Lawson J, Nesbitt R, et al. Aspiration in acute stroke: a clinical study with videofluoroscopy. Q J Med 1993;86:825-9.
10. Aviv JE, Martin JH, Keen MS, et al. Air pulse quantification of supraglottic and pharyngeal sensation: a new technique. Ann Otol Rhinol Laryngol 1993;102:777-80.
11. Aviv JE, Martin JH, Kim T, et al. Laryngopharyngeal sensory discrimination testing and the laryngeal adductor reflex. Ann Otol Rhinol Laryngol 1999;108:725-30.
12. Aviv JE, Martin JH, Jones ME, et al. Age-related changes in pharyngeal and supraglottic sensation. Ann Otol Rhinol Laryngol 1994;103:749-52.
13. Johnson LF, DeMeester TR. Development of the 24-hour intraesophageal pH monitoring composite scoring system. J Clin Gastroenterol 1986;8(Suppl 1):52-8.
14. Savary M, Miller G. The oesophagus. Handbook and atlas of endoscopy. Solothrun, Switzerland: Verlag Gassmann, 1978.
15. Bland M. Clinical measurement. In: Bland M, eds. An introduction to medical statistics.3rd ed. Oxford: University Press, 2000:269-72.
16. Link DT, Willging JP, Miller CK, et al. Pediatric laryngopharyngeal sensory testing during flexible endoscopic evaluation of swallowing: feasible and correlative. Ann Otol Rhinol Laryngol 2000;109:899-905.
17. Fass R, Naliboff B, Higa L, et al. Differential effect of long-term esophageal acid exposure on mechanosensitivity and chemosensitivity in humans. Gastroenterology 1998;115:1363-73.
18. Page AJ, Blackshaw LA. An in vitro study of the properties of vagal afferent fibres innervating the ferret oesophagus and stomach. J Physiol 1998;512:907-16.
19. Mendell DA, Logemann JA. A retrospective analysis of the pharyngeal swallow in patients with a clinical diagnosis of GERD compared with normal controls: a pilot study. Dysphagia 2002;17:220-6.
20. Kastelik JA, Redington AE, Aziz I, et al. Abnormal oesophageal motility in patients with chronic cough. Thorax 2003;58:699-702.
21. Aviv JE. Sensory discrimination in the larynx and hypopharynx. Otolaryngol Head Neck Surg 1997;116:331-4.
22. Bhabu P, Poletto C, Mann E, et al. Thyroarytenoid muscle responses to air pressure stimulation of the laryngeal mucosa in humans. Ann Otol Rhinol Laryngol 2003;112:834-40.
23. Yoshida Y, Tanaka Y, Hirano M, et al. Sensory innervation of the pharynx and larynx. Am J Med 2000;108(Suppl 4a):51-61S.
24. Bradley RM. Sensory receptors of the larynx. Am J Med 2000;108(Suppl 4a):47-50S.