CRTC1/MAML2 fusion transcript in central mucoepidermoid carcinoma of mandible-diagnostic and histogenetic implications

Annals of Diagnostic Pathology

Volumn 14, Issue 6, 2010, Pages 396-401

  Bell, Diana ^a   Holsinger, Christopher F ^a   El Naggar, Adel K ^a  

^a UNIVERSITY OF TEXAS   (United States)

Author keywords

Fusion gene; Histogenesis; Intraosseous mucoepidermoid carcinoma

Indexed keywords

HYBRID PROTEIN; PROTEIN CRTC1; PROTEIN MAML2; UNCLASSIFIED DRUG;

ADULT; ARTICLE; CANCER DIAGNOSIS; CASE REPORT; CHROMOSOME TRANSLOCATION 11; CHROMOSOME TRANSLOCATION 19; DNA SEQUENCE; GENE FUSION; HUMAN; HUMAN TISSUE; MALE; MANDIBLE CANCER; MUCOEPIDERMOID TUMOR; PRIORITY JOURNAL; PROTEIN ANALYSIS; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

ADOLESCENT; ADULT; CARCINOMA, MUCOEPIDERMOID; DNA, NEOPLASM; DNA-BINDING PROTEINS; GENE EXPRESSION REGULATION, NEOPLASTIC; GENE FUSION; HUMANS; MALE; MANDIBULAR NEOPLASMS; MIDDLE AGED; NUCLEAR PROTEINS; TOMOGRAPHY, X-RAY COMPUTED; TRANSCRIPTION FACTORS; YOUNG ADULT;

EID: 78349259281     PISSN: 10929134     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.anndiagpath.2010.05.009     Document Type: Article

References (31)

1. Eversole L.R., Sabes W.R., and Rovin S. Aggressive growth and neoplastic potential of odontogenic cysts: with special reference to central epidermoid and mucoepidermoid carcinomas Cancer 35 1975 270 282
2. Ezsias A., Sugar A.W., and Milling M.A. Central mucoepidermoid carcinoma in a child J Oral Maxillofac Surg 52 1994 512 515
3. Gingell J.C., Beckerman T., and Levy B.A. Central mucoepidermoid carcinoma. Review of the literature and report of a case associated with an apical periodontal cyst Oral Surg Oral Med Oral Pathol 57 1984 436 440
4. Brookstone M.S., and Huvos A.G. Central salivary gland tumors of the maxilla and mandible: a clinicopathologic study of 11 cases with an analysis of the literature J Oral Maxillofac Surg 50 1992 229 236
5. Lebsack J.P., Marrogi A.J., and Martin S.A. Central mucoepidermoid carcinoma of the jaw with distant metastasis: a case report and review of the literature J Oral Maxillofac Surg 48 1990 518 522
6. Maremonti P., Califano L., and Mangone G.M. Intraosseous mucoepidermoid carcinoma. Report of a long-term evolution case Oral Oncol 37 2001 110 113
7. Pons Vicente O., Almendros Marques N., and Berini Aytes L. Minor salivary gland tumors: a clinicopathological study of 18 cases Med Oral Patol Oral Cir Bucal 13 2008 E582 E588
8. Tucci R., Matizonkas-Antonio L.F., and de Carvalhosa A.A. Central mucoepidermoid carcinoma: report of a case with 11 years' evolution and peculiar macroscopical and clinical characteristics Med Oral Patol Oral Cir Bucal 14 2009 E283 E286
9. Rhymes R. Jr., and Hardin J.C. Jr Mucoepidermoid carcinoma: report of case J Oral Surg Anesth Hosp Dent Serv 21 1963 239 242
10. Baj A., Bertolini F., and Ferrari S. Central mucoepidermoid carcinoma of the jaw in a teenager: a case report J Oral Maxillofac Surg 60 2002 207 211
11. Bhaskar S.N. Central mucoepidermoid tumors of the mandible. Report of 2 cases Cancer 16 1963 721 726
12. Browand B.C., and Waldron C.A. Central mucoepidermoid tumors of the jaws. Report of nine cases and review of the literature Oral Surg Oral Med Oral Pathol 40 1975 631 643
13. Browne R.M. Metaplasia and degeneration in odontogenic cysts in man J Oral Pathol 1 1972 145 158
14. Chaudhry A.P., Dedolph T.H. Jr., and Vickers R.A. Muco-epidermoid tumor arising from ectopic minor salivary glands in the maxilla: report of case J Oral Surg Anesth Hosp Dent Serv 19 1961 521 523
15. Dhawan I.K., Bhargava S., and Nayak N.C. Central salivary gland tumors of jaws Cancer 26 1970 211 217
16. Grubka J.M., Wesley R.K., and Monaco F. Primary intraosseous mucoepidermoid carcinoma of the anterior part of the mandible J Oral Maxillofac Surg 41 1983 389 394
17. Achcar Rde O., Nikiforova M.N., and Dacic S. Mammalian mastermind like 2 11q21 gene rearrangement in bronchopulmonary mucoepidermoid carcinoma Hum Pathol 40 2009 854 860
18. Bell D., Luna M.A., and Weber R.S. CRTC1/MAML2 fusion transcript in Warthin's tumor and mucoepidermoid carcinoma: evidence for a common genetic association Genes Chromosomes Cancer 47 2008 309 314
19. Lennerz J.K., Perry A., and Dehner L.P. CRTC1 rearrangements in the absence of t(11;19) in primary cutaneous mucoepidermoid carcinoma Br J Dermatol 161 2009 925 929
20. Lennerz J.K., Perry A., and Mills J.C. Mucoepidermoid carcinoma of the cervix: another tumor with the t(11;19)-associated CRTC1-MAML2 gene fusion Am J Surg Pathol 33 2009 835 843
21. O'Neill I.D. Gefitinib as targeted therapy for mucoepidermoid carcinoma of the lung: possible significance of CRTC1-MAML2 oncogene Lung Cancer 64 2009 129 130
22. Tirado Y., Williams M.D., and Hanna E.Y. CRTC1/MAML2 fusion transcript in high grade mucoepidermoid carcinomas of salivary and thyroid glands and Warthin's tumors: implications for histogenesis and biologic behavior Genes Chromosomes Cancer 46 2007 708 715
23. Holsinger F.C., Owens J.M., and Raymond A.K. Central mucoepidermoid carcinoma of the mandible: tumorigenesis within a keratocyst Arch Otolaryngol Head Neck Surg 128 2002 718 720
24. Melrose R.J., Abrams A.M., and Howell F.V. Mucoepidermoid tumors of the intraoral minor salivary glands: a clinicopathologic study of 54 cases JOral Pathol 2 1973 314 325
25. Pierri L.K., Schneider K.L., and Super S. Intraosseous high-grade mucopidermoid carcinoma with four potential microscopic diagnoses J Oral Med 41 1986 47 50
26. Stoch R.B., and Smith I. Mucoepidermoid carcinoma in the mandible: report of case J Oral Surg 38 1980 56 58
27. Looser K.G., and Kuehn P.G. Primary tumors of the mandible. A study of 49 cases Am J Surg 132 1976 608 614
28. Pincock J.L., and el-Mofty S.K. Recurrence of cystic central mucoepidermoid tumor of the mandible. Report of a case with 3 recurrences in 7 years Int J Oral Surg 14 1985 81 84
29. Stoll H.C., and Marchetta F.C. Tumors of salivary gland origin presenting as primary jaw tumors Oral Surg Oral Med Oral Pathol 10 1957 1262 1267
30. Thomas G., Pandey M., and Mathew A. Primary intraosseous carcinoma of the jaw: pooled analysis of world literature and report of two new cases Int J Oral Maxillofac Surg 30 2001 349 355
31. Behboudi A., Enlund F., and Winnes M. Molecular classification of mucoepidermoid carcinomas-prognostic significance of the MECT1-MAML2 fusion oncogene Genes Chromosomes Cancer 45 2006 470 481