Psoriasis patients have abnormal ceramide profile in stratum corneum

Nishinihon Journal of Dermatology

Volumn 72, Issue 5, 2010, Pages 494-499

  Koyano, Satomi ^a   Hatamochi, Atsushi ^a   Yamazaki, Soji ^a   Ishikawa, Junko ^b   Kitahara, Takashi ^b   Narita, Hirofumi ^b   Kondo, Naoki ^b   Masukawa, Yoshinori ^b  

^a DOKKYO MEDICAL UNIVERSITY   (Japan)

^b KAO CORPORATION   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CERAMIDE;

ARTICLE; CONTROLLED STUDY; HUMAN; PSORIASIS; STRATUM CORNEUM;

EID: 78349258172     PISSN: 03869784     EISSN: None     Source Type: Journal    
DOI: 10.2336/nishinihonhifu.72.494     Document Type: Article

References (11)

1. Imokawa G et al : Decreased level of ceramides in stratum corneum of atopic dermatitis : an etiologic factor in atopic dry skin? J Invest Dermatol 96 : 523-526, 1991.
2. Motta S et al : Ceramide composition of the psoriatic scale. Biochim Biophys Acta 1182 : 147-151, 1993.
3. Lew BL et al : Ceramides and cell signaling molecules in psoriatic epidermis : reduced levels of ceramides, PKC-alpha, and JNK. J Korean Med Sci 21 : 95-99, 2006.
4. Masukawa Y et al : Characterization of overall ceramide species in human stratum corneum. J Lipid Res 49 : 1466-1476, 2008.
5. Ishikawa J et al : The Changes in Ceramide Profile in Atopic Dermatitis Patients. J Invest Dermatol 130 : 2511-2514, 2010.
6. Masukawa Y et al : Comprehensive quantification of ceramide species in human stratum corneum. J Lipid Res 50 : 1708-1719, 2009.
7. Cho Y et al : An inverse relationship between ceramide synthesis and clinical severity in patients with psoriasis. J Korean Med Sci 19 : 859-863, 2004. (Pubitemid 40104880)
8. Kyung-Kook Hong et al : A study on altered expression of serine palmitoyltransferase and ceramidase in psoriatic skin lesion. J Korean Med Sci 22 : 862-867, 2007.
9. Pilgram GS et al : Aberrant lipid organization in stratum corneum of patients with atopic dermatitis and lamellar ichthyosis. J Invest Dermatol 117 : 710-717, 2001.
10. Gooris GS, Bouwstra JA : Infrared spectroscopic study of stratum corneum model membranes prepared from human ceramides, cholesterol, and fatty acids. Biophys J 92 : 2785-2795, 2007.
11. Farwanah H et al : Ceramide profiles of the uninvolved skin in atopic dermatitis and psoriasis are comparable to those of healthy skin. Arch Dermatol Res 296 : 514-521, 2005. (Pubitemid 40603269)