Immunosuppressive sesquiterpenes from Buddleja daviddi

Planta Medica

Volumn 76, Issue 16, 2010, Pages 1882-1887

  Zhang, Wen ^a,b   Yao, Zhi ^a   Zhang, Yan Wen ^a   Zhang, Xing Xiang ^b   Takaishi, Yoshihisa ^c   Duan, Hong Quan ^a  

^a TIANJIN MEDICAL UNIVERSITY   (China)

^b TIANJIN POLYTECHNIC UNIVERSITY   (China)

^c UNIVERSITY OF TOKUSHIMA   (Japan)

Author keywords

Buddleja daviddi; caryophyllane sesquiterpene; cytotoxic activity; humulane sesquiterpene; immunosuppressive activity; Loganiaceae

Indexed keywords

2,6(12),10 HUMULATRIEN 7BETA OL 1 ONE; 2ALPHA ACETOXY 4BETA,5ALPHA HYDROXY ENANTIO CARYOPHYLLA 8(15) EN 3 ONE; 2ALPHA ACETOXY 4BETA,5BETA HYDROXY ENANTIO CARYOPHYLLA 8(15) EN 3 ONE; 2ALPHA ACETOXY 5ALPHA HYDROXY ENANTIO CARYOPHYLLA 8(15) EN 3 ONE; 2ALPHA ACETOXY-5ALPHA METHOXY ENANTIO CARYOPHYLLA 8(15) EN 3 ONE; 2BETA ACETOXY 4 CARYOPHYLLEN 8BETA OL 3 ONE; SESQUITERPENE; UNCLASSIFIED DRUG;

ARTICLE; BUDDLEJA DAVIDDI; CARBON NUCLEAR MAGNETIC RESONANCE; DRUG CYTOTOXICITY; DRUG ISOLATION; DRUG STRUCTURE; FEMALE; HELA CELL; HUMAN; HUMAN CELL; IMMUNOSUPPRESSIVE TREATMENT; MEDICINAL PLANT; PROTON NUCLEAR MAGNETIC RESONANCE;

ANTINEOPLASTIC AGENTS, PHYTOGENIC; BUDDLEJA; CELL LINE, TUMOR; HELA CELLS; HUMANS; IMMUNOSUPPRESSIVE AGENTS; MOLECULAR STRUCTURE; NEOPLASMS; PHYTOTHERAPY; PLANT EXTRACTS; RHIZOME; SESQUITERPENES;

BUDDLEJA; LOGANIACEAE;

EID: 78349256702     PISSN: 00320943     EISSN: 14390221     Source Type: Journal    
DOI: 10.1055/s-0030-1249974     Document Type: Article

References (20)

1. Wan D R., Chen W J., Qian C, Lei Y S. The antirheumatic Tujia herbal-medicine in the western of Hubei. J Chin Med Mater 1993 18 581-584
2. Houghton P J. Lignans and neolignans from Buddleja davidii. Phytochemistry 1985 24 819-826
3. Houghton P J. Phenylpropanoid glycosides in Buddleja davidii. J Nat Prod 1985 48 1005-1006
4. Yoshida T, Uchida M, Okuda T. Buddledin A, B, C, piscicidal sesquiterpenes from Buddleja davidii Franch. Tetrahedron Lett 1976 17 3717-3720
5. Yamamoto A, Nitta S, Miyase T, Ueno A, Wu L J. Phenylethanoid and lignan-iridoid complex glycosides from roots of Buddleja davidii. Phytochemistry 1993 32 421-425
6. Lu J H., Tu G Z., Zhao Y Y., Lv Y, Liu L Y., Wu Y S. Structural determination of novel terpenes from Buddleia lindleyana. Magn Reson Chem 2004 42 893-897
7. Liao Y H., Houghton P J., Hoult J R. S. Novel and known constituents from Buddleja species and their activity against leukocyte eicosanoid generation. J Nat Prod 1999 62 1241-1245
8. Sahyrbekov D T., Atazhanova G A., Kulyyasov A T., Raldugin V A., Gatilov Y V., Shakirov M M., Edil'baeva T T., Turdybekov K M., Adekenov S M. Buddledin C from prostrate and selective synthesis of its epoxy derivative. Chem Nat Compounds 2006 42 41-45
9. Yoshida T, Nobuhara J, Uchida M, Okuda T. Studies on the constituents Buddleja species. I. Structures of Buddledin A and B. Two new toxic sesquiterpenes from Buddleja davidii Franch. Chem Pharm Bull 1978 26 2535-2542
10. Yoshida T, Nobuhara J, Fujii N, Okuda T. Studies on the constituents of Budddleja species. II. Buddledin C, D and E. New sesquiterpenes from Buddleja davidii Franch. Chem Pharm Bull 1978 26 2543-2549
11. Yarovaya O I., Korchagina D V., Rybalova T V., Gatilov Y V., Polovinka M P., Barkhash V A. Reactions of caryophyllene, isocaryophyllene, and their epoxy derivatives with acetonitrile under ritter reaction conditions. Russian J Org Chem 2004 40 1593-1598
12. Wang G H., Ahmed A F., Sheu Y C., Wang L T., Shen J H. Suberosols AD, four new sesquiterpenes with -caryophyllene skeletons from a Taiwanses gorgonian coral Subergorgia suberosa. J Nat Prod 2002 65 887-891
13. Banerji J, Das B, Chatterjee A, Shoolery J N. Gadain, a lignan from Jatropha gossypifolia. Phytochemistry 1984 23 2323-2327
14. Zhang G, Shimokawa S, Mochizuki M, Kumamoto T, Nakanishi W, Watanabe T, Ishikawa T, Matsumoto K, Tashima K, Horie S, Higuchi Y, Dominguez O P. Chemical constituents of Aristolochia constricta: antispasmodic effects of its constituents in guinea-pig ileum and isolation of a diterpeno-lignan hybrid. J Nat Prod 2008 71 1167-1172
15. Inara C P., Isabele R N., Lucia M X. L. Configurational analysis of cubebins and bicubebin from Aristolochia lagesiana and Aristolochia pubescens. Phytochemistry 2006 67 735-742
16. Marco J A., Cervera J F. S., Morante M D., Lliso V G., Xirau J V., Jakupovic J. Tricyclic sesquiterpenes from Artemisia chamaemelifolia. Phytochemistry 1996 41 837-844
17. Amaro L J. M., Fronczek F, Massanet G, Pando E, Rodríguez L F., Watkins S, Zubía E. Meridinol, a lignan from Zanthoxylum fagara. Phytochemistry 1988 27 3933-3935
18. Pieters L, Bruyne T, Claeys M, Vlietinck A. Isolation of a dihydrobenzofuran lignan from South American Dragon's blood (Croton SPP.) as an inhibitor of cell proliferation. J Nat Prod 1993 56 899-906
19. Waibel R, Benirschke G, Benirschke M, Achenbach H. Sesquineolignans and other constituents from the seeds of Joannesia princeps. Phytochemistry 2003 62 805-811
20. Shen G X. Experimental techniques of modern immunology. Hubei Hubei Scientific and Technical Press 1998 309-310