메뉴 건너뛰기




Volumn 9, Issue 21, 2010, Pages 4266-4268

Cdc5 blocks in vivo rad53 activity, but not in situ activity (ISA)

Author keywords

Adaptation; CDC5; Checkpoint; DNA damage; ISA; RAD53

Indexed keywords

ATR PROTEIN; CDC 5 PROTEIN; CHECKPOINT KINASE 2; MEC1 PROTEIN; PROTEIN; UNCLASSIFIED DRUG;

EID: 78349254183     PISSN: 15384101     EISSN: 15514005     Source Type: Journal    
DOI: 10.4161/cc.9.21.13637     Document Type: Review
Times cited : (6)

References (25)
  • 1
    • 42949130159 scopus 로고    scopus 로고
    • Colocalization of sensors is sufficient to activate the DNA damage checkpoint in the absence of damage
    • Bonilla CY, Melo JA, Toczyski DP. Colocalization of sensors is sufficient to activate the DNA damage checkpoint in the absence of damage. Mol Cell 2008; 30:267-76.
    • (2008) Mol Cell , vol.30 , pp. 267-276
    • Bonilla, C.Y.1    Melo, J.A.2    Toczyski, D.P.3
  • 2
    • 0032962928 scopus 로고    scopus 로고
    • Role of a complex containing Rad17, Mec3 and Ddc1 in the yeast DNA damage checkpoint pathway
    • Kondo T, Matsumoto K, Sugimoto K. Role of a complex containing Rad17, Mec3 and Ddc1 in the yeast DNA damage checkpoint pathway. Mol Cell Biol 1999; 19:1136-43.
    • (1999) Mol Cell Biol , vol.19 , pp. 1136-1143
    • Kondo, T.1    Matsumoto, K.2    Sugimoto, K.3
  • 3
    • 33845607102 scopus 로고    scopus 로고
    • The Checkpoint Clamp Activates Mec1 Kinase during Initiation of the DNA Damage Checkpoint
    • DOI 10.1016/j.molcel.2006.11.027, PII S1097276506008239
    • Majka J, Niedziela-Majka A, Burgers PM. The checkpoint clamp activates Mec1 kinase during initiation of the DNA damage checkpoint. Mol Cell 2006; 24:891-901. (Pubitemid 44960097)
    • (2006) Molecular Cell , vol.24 , Issue.6 , pp. 891-901
    • Majka, J.1    Niedziela-Majka, A.2    Burgers, P.J.3
  • 4
    • 0035498938 scopus 로고    scopus 로고
    • Two checkpoint complexes are independently recruited to sites of DNA damage in vivo
    • Melo JA, Cohen J, Toczyski DP. Two checkpoint complexes are independently recruited to sites of DNA damage in vivo. Genes Dev 2001; 15:2809-21. (Pubitemid 33042052)
    • (2001) Genes and Development , vol.15 , Issue.21 , pp. 2809-2821
    • Melo, J.A.1    Cohen, J.2    Toczyski, D.P.3
  • 5
    • 71149093704 scopus 로고    scopus 로고
    • The unstructured C-terminal tail of the 9-1-1 clamp subunit Ddc1 activates Mec1/ATR via two distinct mechanisms
    • Navadgi-Patil VM, Burgers PM. The unstructured C-terminal tail of the 9-1-1 clamp subunit Ddc1 activates Mec1/ATR via two distinct mechanisms. Mol Cell 2009; 36:743-53.
    • (2009) Mol Cell , vol.36 , pp. 743-753
    • Navadgi-Patil, V.M.1    Burgers, P.M.2
  • 6
    • 33644757806 scopus 로고    scopus 로고
    • TopBP1 activates the ATR-ATRIP complex
    • Kumagai A, Lee J, Yoo HY, Dunphy WG. TopBP1 activates the ATR-ATRIP complex. Cell 2006; 124:943-55.
    • (2006) Cell , vol.124 , pp. 943-955
    • Kumagai, A.1    Lee, J.2    Yoo, H.Y.3    Dunphy, W.G.4
  • 7
    • 44849093460 scopus 로고    scopus 로고
    • TopBP1 activates ATR through ATRIP and a PIKK regulatory domain
    • Mordes DA, Glick GG, Zhao R, Cortez D. TopBP1 activates ATR through ATRIP and a PIKK regulatory domain. Genes Dev 2008; 22:1478-89.
    • (2008) Genes Dev , vol.22 , pp. 1478-1489
    • Mordes, D.A.1    Glick, G.G.2    Zhao, R.3    Cortez, D.4
  • 8
    • 0032133216 scopus 로고    scopus 로고
    • MEC1-dependent phosphorylation of Rad9p in response to DNA damage
    • Emili A. MEC1-dependent phosphorylation of Rad9p in response to DNA damage. Mol Cell 1998; 2:183-9.
    • (1998) Mol Cell , vol.2 , pp. 183-189
    • Emili, A.1
  • 9
    • 0032504069 scopus 로고    scopus 로고
    • Rad53 FHA domain associated with phosphorylated Rad9 in the DNA damage checkpoint
    • Sun Z, Hsiao J, Fay DS, Stern DF. Rad53 FHA domain associated with phosphorylated Rad9 in the DNA damage checkpoint. Science 1998; 281:272-4.
    • (1998) Science , vol.281 , pp. 272-274
    • Sun, Z.1    Hsiao, J.2    Fay, D.S.3    Stern, D.F.4
  • 10
    • 0032189952 scopus 로고    scopus 로고
    • The budding yeast Rad9 checkpoint protein is subjected to Mec1/Tel1-dependent hyperphosphorylation and interacts with Rad53 after DNA damage
    • Vialard JE, Gilbert CS, Green CM, Lowndes NF. The budding yeast Rad9 checkpoint protein is subjected to Mec1/Tel1-dependent hyperphosphorylation and interacts with Rad53 after DNA damage. EMBO J 1998; 17:5679-88.
    • (1998) EMBO J , vol.17 , pp. 5679-5688
    • Vialard, J.E.1    Gilbert, C.S.2    Green, C.M.3    Lowndes, N.F.4
  • 11
    • 0034881760 scopus 로고    scopus 로고
    • Budding yeast Rad9 is an ATP-dependent Rad53 activating machine
    • Gilbert CS, Green CM, Lowndes NF. Budding yeast Rad9 is an ATP-dependent Rad53 activating machine. Mol Cell 2001; 8:129-36.
    • (2001) Mol Cell , vol.8 , pp. 129-136
    • Gilbert, C.S.1    Green, C.M.2    Lowndes, N.F.3
  • 13
    • 0027421043 scopus 로고
    • Loss of a yeast telomere: Arrest, recovery and chromosome loss
    • Sandell LL, Zakian VA. Loss of a yeast telomere: arrest, recovery and chromosome loss. Cell 1993; 75:729-39.
    • (1993) Cell , vol.75 , pp. 729-739
    • Sandell, L.L.1    Zakian, V.A.2
  • 14
    • 0030885666 scopus 로고    scopus 로고
    • CDC5 and CKII control adaptation to the yeast DNA damage checkpoint
    • Toczyski DP, Galgoczy DJ, Hartwell LH. CDC5 and CKII control adaptation to the yeast DNA damage checkpoint. Cell 1997; 90:1097-106.
    • (1997) Cell , vol.90 , pp. 1097-1106
    • Toczyski, D.P.1    Galgoczy, D.J.2    Hartwell, L.H.3
  • 15
    • 75749156256 scopus 로고    scopus 로고
    • CDC5 inhibits the hyperphosphorylation of the checkpoint kinase Rad53, leading to checkpoint adaptation
    • Vidanes GM, Sweeney FD, Galicia S, Cheung S, Doyle JP, Durocher D, et al. CDC5 inhibits the hyperphosphorylation of the checkpoint kinase Rad53, leading to checkpoint adaptation. PLoS Biol 2010; 8:1000286.
    • (2010) PLoS Biol , vol.8 , pp. 1000286
    • Vidanes, G.M.1    Sweeney, F.D.2    Galicia, S.3    Cheung, S.4    Doyle, J.P.5    Durocher, D.6
  • 16
    • 0035901555 scopus 로고    scopus 로고
    • Sld3, which interacts with Cdc45 (Sld4), functions for chromosomal DNA replication in Saccharomyces cerevisiae
    • Kamimura Y, Tak YS, Sugino A, Araki H. Sld3, which interacts with Cdc45 (Sld4), functions for chromosomal DNA replication in Saccharomyces cerevisiae. EMBO J 2001; 20:2097-107.
    • (2001) EMBO J , vol.20 , pp. 2097-2107
    • Kamimura, Y.1    Tak, Y.S.2    Sugino, A.3    Araki, H.4
  • 18
    • 77957149919 scopus 로고    scopus 로고
    • Checkpoint Dependent Inhibition of DNA Replication Initiation via Sld3 and Dbf4 Phosphorylation
    • In press
    • Zegerman P, Diffley JFX. Checkpoint Dependent Inhibition of DNA Replication Initiation via Sld3 and Dbf4 Phosphorylation. Nature 2010; In press.
    • (2010) Nature
    • Zegerman, P.1    Diffley, J.F.X.2
  • 19
    • 0033570894 scopus 로고    scopus 로고
    • Activation of Rad53 kinase in response to DNA damage and its effect in modulating phosphorylation of the lagging strand DNA polymerase
    • Pellicioli A, Lucca C, Liberi G, Marini F, Lopes M, Plevani P, et al. Activation of Rad53 kinase in response to DNA damage and its effect in modulating phosphorylation of the lagging strand DNA polymerase. EMBO J 1999; 18:6561-72.
    • (1999) EMBO J , vol.18 , pp. 6561-6572
    • Pellicioli, A.1    Lucca, C.2    Liberi, G.3    Marini, F.4    Lopes, M.5    Plevani, P.6
  • 20
    • 33645212498 scopus 로고    scopus 로고
    • Activation of the checkpoint kinase Rad53 by the phosphatidyl inositol kinase-like kinase Mec1
    • Ma JL, Lee SJ, Duong JK, Stern DF. Activation of the checkpoint kinase Rad53 by the phosphatidyl inositol kinase-like kinase Mec1. J Biol Chem 2006; 281:3954-63.
    • (2006) J Biol Chem , vol.281 , pp. 3954-3963
    • Ma, J.L.1    Lee, S.J.2    Duong, J.K.3    Stern, D.F.4
  • 21
    • 0042470439 scopus 로고    scopus 로고
    • Rad53 phosphorylation site clusters are important for Rad53 regulation and signaling
    • Lee SJ, Schwartz MF, Duong JK, Stern DF. Rad53 phosphorylation site clusters are important for Rad53 regulation and signaling. Mol Cell Biol 2003; 23:6300-14.
    • (2003) Mol Cell Biol , vol.23 , pp. 6300-6314
    • Lee, S.J.1    Schwartz, M.F.2    Duong, J.K.3    Stern, D.F.4
  • 22
    • 23244444605 scopus 로고    scopus 로고
    • Saccharomyces cerevisiae Rad9 acts as a Mec1 adaptor to allow Rad53 activation
    • Sweeney FD, Yang F, Chi A, Shabanowitz J, Hunt DF, Durocher D. Saccharomyces cerevisiae Rad9 acts as a Mec1 adaptor to allow Rad53 activation. Curr Biol 2005; 15:1364-75.
    • (2005) Curr Biol , vol.15 , pp. 1364-1375
    • Sweeney, F.D.1    Yang, F.2    Chi, A.3    Shabanowitz, J.4    Hunt, D.F.5    Durocher, D.6
  • 23
    • 4444353636 scopus 로고    scopus 로고
    • Regulation of protein kinases: Controlling activity through activation segment conformation
    • DOI 10.1016/j.molcel.2004.08.024, PII S1097276504004800
    • Nolen B, Taylor S, Ghosh G. Regulation of protein kinases; controlling activity through activation segment conformation. Mol Cell 2004; 15:661-75. (Pubitemid 39194898)
    • (2004) Molecular Cell , vol.15 , Issue.5 , pp. 661-675
    • Nolen, B.1    Taylor, S.2    Ghosh, G.3
  • 24
    • 18344366048 scopus 로고    scopus 로고
    • Getting in and out of mitosis with Polo-like kinase-1
    • van Vugt MA, Medema RH. Getting in and out of mitosis with Polo-like kinase-1. Oncogene 2005; 24:2844-59.
    • (2005) Oncogene , vol.24 , pp. 2844-2859
    • Van Vugt, M.A.1    Medema, R.H.2
  • 25
    • 75749130721 scopus 로고    scopus 로고
    • A mitotic phosphorylation feedback network connects Cdk1, Plk1, 53BP1 and Chk2 to inactivate the G(2)/M DNA damage checkpoint
    • van Vugt MA, Gardino AK, Linding R, Ostheimer GJ, Reinhardt HC, Ong SE, et al. A mitotic phosphorylation feedback network connects Cdk1, Plk1, 53BP1 and Chk2 to inactivate the G(2)/M DNA damage checkpoint. PLoS Biol 2010; 8:1000287.
    • (2010) PLoS Biol , vol.8 , pp. 1000287
    • Van Vugt, M.A.1    Gardino, A.K.2    Linding, R.3    Ostheimer, G.J.4    Reinhardt, H.C.5    Ong, S.E.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.