Studies of anti-HIV transcription inhibitor quinolones: Identification of potent N1-vinyl derivatives

ChemMedChem

Volumn 5, Issue 11, 2010, Pages 1880-1892

  Tabarrini, Oriana ^a   Massari, Serena ^a   Daelemans, Dirk ^b   Meschini, Francesco ^a   Manfroni, Giuseppe ^a   Bottega, Laura ^c   Gatto, Barbara ^c   Palumbo, Manlio ^c   Pannecouque, Christophe ^b   Cecchetti, Violetta ^a  

^a UNIVERSITY OF PERUGIA   (Italy)

^b REGA INSTITUTE FOR MEDICAL RESEARCH   (Belgium)

^c UNIVERSITY OF PADOVA   (Italy)

Author keywords

1 vinylquinolones; anti HIV quinolones; antiviral agents; medicinal chemistry; transcription inhibitors

Indexed keywords

6 DESFLUOROQUINOLONE DERIVATIVE; ANTI HUMAN IMMUNODEFICIENCY VIRUS AGENT; QUINOLONE DERIVATIVE; TRANSACTIVATOR PROTEIN; UNCLASSIFIED DRUG; VINYL DERIVATIVE;

ANTIVIRAL ACTIVITY; ARTICLE; DRUG DESIGN; DRUG IDENTIFICATION; DRUG STRUCTURE; DRUG SYNTHESIS; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN IMMUNODEFICIENCY VIRUS 1 INFECTION; HUMAN IMMUNODEFICIENCY VIRUS 2; HUMAN IMMUNODEFICIENCY VIRUS 2 INFECTION; PHARMACOPHORE; PRIORITY JOURNAL; VIRUS TRANSCRIPTION;

ANTI-HIV AGENTS; CELL LINE; HIV INFECTIONS; HUMANS; QUINOLONES; STRUCTURE-ACTIVITY RELATIONSHIP; TRANSCRIPTION, GENETIC; VINYL COMPOUNDS; VIRUS REPLICATION;

EID: 78349237787     PISSN: 18607179     EISSN: 18607187     Source Type: Journal    
DOI: 10.1002/cmdc.201000267     Document Type: Article

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