Improvement in β-cell function in patients with normal and hyperglycemia following Roux-en-Y gastric bypass surgery

American Journal of Physiology - Endocrinology and Metabolism

Volumn 299, Issue 5, 2010, Pages

  Lin, Edward ^a   Liang, Zhe ^a   Frediani, Jennifer ^a   Davis Jr , Scott S ^a   Sweeney, John F ^a   Ziegler, Thomas R ^b   Phillips, Lawrence S ^b   Gletsu Miller, Nana ^a  

^a EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b Atlanta Clinical and Translational Science Institute   (United States)

Author keywords

Adipose tissue mass; Disposition index; Weight loss

Indexed keywords

GLUCOSE; INSULIN;

ADIPOSE TISSUE; ADULT; ANTHROPOMETRIC PARAMETERS; ARTICLE; CLINICAL ARTICLE; ENDOCRINE FUNCTION TEST; FEMALE; GLUCOSE BLOOD LEVEL; GLYCEMIC CONTROL; HOMEOSTATIC MODEL ASSESSMENT; HUMAN; HYPERGLYCEMIA; INSULIN RESISTANCE; INSULIN RESPONSE; INSULIN SENSITIVITY; INTRAVENOUS GLUCOSE TOLERANCE TEST; OBESITY; PANCREAS ISLET BETA CELL; PANCREAS ISLET CELL FUNCTION; PREOPERATIVE PERIOD; PRIORITY JOURNAL; ROUX Y ANASTOMOSIS; WEIGHT REDUCTION; ANTHROPOMETRY; BODY PLETHYSMOGRAPHY; CHI SQUARE DISTRIBUTION; GLUCOSE TOLERANCE TEST; LONGITUDINAL STUDY; MORBID OBESITY; PATHOLOGY; PATHOPHYSIOLOGY; PHYSIOLOGY; SECRETION; STOMACH BYPASS;

ADIPOSE TISSUE; ADULT; ANTHROPOMETRY; CHI-SQUARE DISTRIBUTION; FEMALE; GASTRIC BYPASS; GLUCOSE TOLERANCE TEST; HUMANS; HYPERGLYCEMIA; INSULIN RESISTANCE; INSULIN-SECRETING CELLS; LONGITUDINAL STUDIES; OBESITY, MORBID; PLETHYSMOGRAPHY, WHOLE BODY;

EID: 78349235082     PISSN: 01931849     EISSN: 15221555     Source Type: Journal    
DOI: 10.1152/ajpendo.00405.2010     Document Type: Article

References (48)

1. Abate N, Garg A, Peshock RM, Stray-Gundersen J, Adams-Huet B, Grundy SM. Relationship of generalized and regional adiposity to insulin sensitivity in men with NIDDM. Diabetes 45: 1684-1693, 1996.
2. Abdul-Ghani MA, Jenkinson CP, Richardson DK, Tripathy D, De- Fronzo RA. Insulin secretion and action in subjects with impaired fasting glucose and impaired glucose tolerance. Results from the Veteran's Administration Genetic Epidemiology Study. Diabetes 55: 1430-1435, 2006. (Pubitemid 44195383)
3. American-Diabetes-Association. Diagnosis and classification of diabetes mellitus. Diabetes Care 30: S42-S47, 2007.
4. Ballantyne GH, Farkas D, Laker S, Wasilewski A. Short-term changes in insulin resistance following weight loss surgery for morbid obesity: laparoscopic adjustable gastric banding versus laparoscopic Roux-en-Y gastric bypass. Obes Surg 16: 1189-1197, 2006. (Pubitemid 44433156)
5. Bays HE, Chapman RH, Grandy S. The relationship of body mass index to diabetes mellitus, hypertension and dyslipidaemia: comparison of data from two national surveys. Int J Clin Pract 61: 737-747, 2007. (Pubitemid 46587875)
6. Bergman RN. Toward physiological understanding of glucose tolerance. Minimal-model approach. Diabetes 38: 1512-1527, 1989.
7. Bergman RN, Ader M, Huecking K, Van Critters G. Accurate assessment of beta-cell function. The hyperbolic correction. Diabetes 51: S212-S220, 2002. (Pubitemid 34761518)
8. Briatore L, Salani B, Andraghetti G, Danovaro C, Sferrazzo E, Scopinaro N, Adami GF, Maggi D, Cordera R. Restoration of acute insulin response in T2DM subjects 1 month after biliopancreatic diversion. Obesity 16: 77-81, 2008.
9. Buchwald H, Avidor Y, Braunwald E, Jensen MD, Pories WJ, Fahrbach K, Schoelles K. Bariatric surgery. A systemic reveiw and meta-analysis. JAMA 292: 1724-1737, 2004.
10. Bunck MC, Diamant M, Corner A, Eliasson B, Malloy JL, Shaginian RM, Deng W, Kendall DM, Taskinen MR, Smith U, Yki-Jarvinen H, Heine RJ. One-year treatment with exenatide improves β-cell function, compared with insulin glargine, in metformin-treated type 2 diabetic patients. Diabetes Care 32: 762-768, 2009.
11. Camastra S, Manco M, Mari A, Baldi S, Gastaldelli A, Greco AV, Mingrone G, Ferrannini E. B-cell function in morbidly obese subjects during free living. Long-term effects of weight loss. Diabetes 54: 2382-2389, 2005.
12. Camastra S, Manco M, Mari A, Greco AV, Frascerra S, Mingrone G, Ferrannini E. B-cell function in severely obese type 2 diabetic patients. Diabetes Care 30: 1002-1004, 2007.
13. Carr DB, Utzschneider KM, Boyko EJ, Asberry PJ, Hull RL, Kodama K, Callahan HS, Matthys CC, Leonetti DL, Schwartz RS, Kahn SE, Fujimoto WY. A reduced-fat diet and aerobic exercise in Japanese Americans with impaired glucose tolerance decreases intra-abdominal fat and improves insulin sensitivity but not b-cell function. Diabetes 54: 340-347, 2005.
14. Cnop M, Vidal J, Hull RL, Utzschneider KM, Carr DB, Schraw T, Scherer PE, Boyko EJ, Fujimoto WY, Kahn SE. Progressive loss of B-cell function leads to worsening glucose tolerance in first-degree relative of subjects with type 2 diabetes. Diabetes Care 30: 677-682, 2007.
15. Dixon JB, O'Brien PE, Playfair J, Chapman L, Schachter LM, Skinner S, Proietto J, Bailey M, Anderson M. Adjustable gastric banding and conventional therapy for type 2 diabetes: a randomized controlled trial. JAMA 299: 316-323, 2008.
16. Faerch K, Vaag A, Holst JJ, Hansen T, Jorgensen T, Borch-Johnsen K. Natural history of insulin sensitivity and insulin secretion in the progression from normal glucose tolerance to impaired fasting glycemia and impaired glucose tolerance-the Inter99 study. Diabetes Care 32: 439-444, 2009.
17. Ferrannini E, Mingrone G. Impact of different bariatric surgical procedures on insulin action and beta-cell function in type 2 diabetes. Diabetes Care 32: 514-520, 2009.
18. Festa A, Williams K, D'Agostino R, Wagenknecht LE, Haffner SM. The natural course of b-cell function in nondiabetic and diabetes individuals. The Insulin Resistance Atherosclerosis Study. Diabetes 55: 1114-1120, 2006.
19. Garcia-Fuentes E, Garcia-Almeida JM, Garcia-Arnes J, Rivas-Marin R, Gallego-Perales JL, Gonzalez-Jimenez B, Cardona I, Garcia-Serrano S, Garriga MJ, Gonzalo M, Ruiz-de-Adana MS, Soriguer F. Morbidly obese individuals with impaired fasting glucose have a specific pattern of insulin secretion and sensitivity: effect of weight loss after bariatric surgery. Obes Surg 16: 1179-1188, 2006.
20. Gletsu-Miller N, Hansen JM, Jones DP, Go YM, Torres WE, Ziegler TR, Lin E. Loss of total and visceral adipose tissue mass predicts decreases in oxidative stress after weight loss surgery. Obesity 17: 439-446, 2009.
21. Guidone C, Manco M, Valera-Mora E, Iaconelli A, Gniuli D, Mari A, Nanni G, Castagneto M, Calvani M, Mingrone G. Mechanisms of recovery from type 2 diabetes after malabsorptive bariatric surgery. Diabetes 55: 2025-2031, 2006.
22. Guldstrand M, Ahren B, Adamson U. Improved β-cell function after standardized weight reduction in severely obese subjects. Am J Physiol Endocrinol Metab 284: E557-E565, 2003.
23. Haffner SM, Howard G, Mayer E, Bergman RN, Savage PJ, Rewers M, Mykkanen L, Karter AJ, Hamman R, Saad MF. Insulin sensitivity and acute insulin response in African Americans, Non-Hispanic Whites, and Hispanics with NIDDM: The Insulin Resistance Atherosclerosis Study. Diabetes 46: 63-69, 1997. (Pubitemid 27009951)
24. Kahn SE, Prigeon RL, McCulloch DK, Boyko EJ, Bergman RN, Schwartz MW, Neifing JL, Ward WK, Beard JC, Palmer JP, Porte D Jr. Quantification of the relationship between insulin sensitivity and beta-cell function in human subjects Evidence for a hyperbolic function. Diabetes 42: 1663-1672, 1993.
25. Laferrere B, Teixeira J, McGinty J, Tran H, Egger JR, Colarusso A, Kovack B, Bawa B, Koshy N, Lee H, Yapp K, Olivan B. Effect of weight loss by gastric bypass surgery versus hypocaloric diet on glucose and incretin levels in patients with type 2 diabetes. J Clin Endocrinol Metab 93: 2479-2485, 2008.
26. Letiexhe MR, Desaive C, Lefebvre PJ, Scheen AJ. Intact cross-talk between insulin secretion and insulin action after postgastroplasty recovery of ideal body weight in severely obese patients. Int J Obes 28: 821-823, 2004.
27. Lin E, Davis SS, Srinivasan J, Sweeney JF, Ziegler TR, Phillips LS, Gletsu-Miller N. Dual mechanism for type-2 diabetes resolution after Roux-en-Y gastric bypass. Am Surgeon 6: 498-503, 2009.
28. Lin E, Gletsu N, Fugate K, McClusky D, Ziegler TR, Gu LH, Papanicolaou DA, Ramshaw BJ, Smith CD. The effects of gastric division on systemic ghrelin concentrations in the morbidly obese. Arch Surg 139: 780-784, 2003.
29. Lin E, Phillips LS, Ziegler TR, Schmolzer B, Kongjun W, Gu LH, Khaitan L, Lynch SA, Torres WE, Smith CD, Gletsu-Miller N. Increases in adiponectin predict improved liver, but not peripheral, insulin sensitivity in severely obese women during weight loss. Diabetes 56: 735-742, 2007.
30. Mari A, Manco M, Guidone C, Nanni G, Castagneto M, Mingrone G, Ferrannini E. Restoration of normal glucose tolerance in severely obese patients after bilio-pancreatic diversion: role of insulin sensitivity and beta-cell function. Diabetologia 49: 2136-2143, 2006.
31. Mari A, Tura A, Pacini G, Kautzky-Willer A, Ferrannini E. Relationships between insulin secretion after intravenous and oral glucose administration in subjects with glucose tolerance ranging from normal to overt diabetes. Diabet Med 25: 671-677, 2008.
32. Matthews DR, Hosker JP, Rudenski AS, Naylor BA, Treacher DF, Turner RC. Homeostasis model assessment: insulin resistance and β-cell function from fasting plasma glucose and insulin concentrations in man. Diabetologia 28: 412-419, 1985.
33. Minderico CS, Silva AM, Teixeira PJ, Sardinha LB, Hull HR, Fields DA. Validity of air-displacement plethysmography in the assessment of body composition changes in a 16-month weight loss program. Nutr Metab (Lond) 3: 32, 2006.
34. Morinigo R, Lacy A, Casamitjana R, Delgado S, Gomis R, Vidal J. GLP-1 and changes in glucose tolerance following gastric bypass surgery in morbidly obese subjects. Obes Surg 16: 1594-1601, 2006.
35. Muscelli E, Mingrove G, Camastra S, Manco M, Pereira JA, Pareja JC, Ferrrannini E. Differential effect of weight loss on insulin resistance in surgically treated obese patients. Am J Med 118: 51-57, 2005.
36. Perugini RA, Quarfordt SH, Baker S, Czerniach DR, Litwin DEM, Kelly JJ. Metabolic characterization of nondiabetic severely obese patients undergoing roux-en-y gastric bypass on insulin-glucose homeostasis. J Gastrointest Surg 11: 1083-1090, 2007.
37. Polyzogopoulou EV, Kalfarentzos F, Vagenakis AG, Alexandrides TK. Restoration of euglycemia and normal acute insulin response to glucose in obese subjects with type 2 diabetes following bariatric surgery. Diabetes 52: 1098-1103, 2003.
38. Pontiroli AE, Pizzocri P, Librenti MC, Vedani P, Marchi M, Cucchi E, Orena C, Paganelli M, Giacomelli M, Ferla G, Folli F. Laparoscopic adjustable gastric banding for the treatment of morbid (grade 3) obesity and its metabolic complications: a three-year study. J Clin Endocrinol Metab 87: 3555-3561, 2002.
39. Pories WJ. Bariatric surgery: risks and rewards. J Clin Endocrinol Metab 93: S89-S96, 2008.
40. Radikova Z, Koska J, Huckova M, Ksinantova L, Imrich R, Vigas M, Trnovec T, Langer P, Sebokova E, Klimes I. Insulin sensitivity indices: a proposal of cut-off points for simple indentification of insulin-resistant subjects. Exp Clin Endocrinol Diabetes 115: 249-256, 2006. (Pubitemid 44065178)
41. Salinari S, Bertuzzi A, Asnaghi S, Guidone C, Manco M, Mingrone G. First phase insulin secretion restoration and differential response to glucose load depending on the route of administration in type 2 diabetic subjects after bariatric surgery. Diabetes Care 32: 375-380, 2009.
42. Sjostrom L, Lindroos AK, Peltonen M, Torgerson J, Bouchard C, Carlsson B, Dahlgren S, Larsson B, Narbro K, Sjostrom CD, Sullivan M, Wedel H. Lifestyle, diabetes, and cardiovascular risk factors 10 years after bariatric surgery. New Engl J Med 351: 2683-2693, 2004. (Pubitemid 39665322)
43. Slentz CA, Tanner CJ, Bateman LA, Durheim MT, Huffman KM, Houmard JA, Kraus WE. Effects of exercise training intensity on pancreatic β-cell function. Diabetes Care 32: 1807-1811, 2009.
44. Utzschneider KM, Carr DB, Hull RL, Kodama K, Shofer JB, Retzlaff BM, Knopp RH, Khan SE. Impact of intraabdominal fat and age on insulin sensitivity and β-cell function. Diabetes 53: 2867-2872, 2004. (Pubitemid 39425912)
45. Utzschneider KM, Tong J, Montgomery B, Udayasankar J, Gerchman F, Marcovina SM, Watson AD, Ligueros-Saylan MA, Foley JE, Holst JJ, Deacon CF, Kahn SE. The dipeptidyl peptidase-4 inhibitor vildagliptin improves β-cell function and insulin sensitivity in subjects with impaired fasting glucose. Diabetes Care 31: 108-113, 2008.
46. Vidal J, Nicolau J, Romero F, Casamitjana R, Mombian D, Conget I, Morinigo R, Lacy AM. Long-term effects of roux-en-y gastric bypass surgery on plasma glucagon-like peptide-1 and islet function in morbidly obese subjects. J Clin Endocrinol Metab 94: 884-891, 2009.
47. Weyer C, Bogardus C, Mott DM, Pratley RE. The natural history of insulin secretory dysfunction and insulin resistance in the pathogenesis of type 2 diabetes mellitus. J Clin Invest 104: 787-794, 1999. (Pubitemid 29536364)
48. Xiang AH, Wang C, Peters RK, Trigo E, Kjos SL, Buchanan TA. Coordinate changes in plasma glucose and pancreatic b-cell function in Latino women at high risk for type 2 diabetes. Diabetes 55: 1074-1079, 2006. (Pubitemid 44100184)