Temporal trends, risk factors and outcomes in albicans and non-albicans candidaemia: an international epidemiological study in four multidisciplinary intensive care units

International Journal of Antimicrobial Agents

Volumn 33, Issue 6, 2009, Pages 554.e1-554.e7

  Holley, Anthony ^a,b   Dulhunty, Joel ^a,b   Blot, Stijn ^c,d,e   Lipman, Jeffrey ^a,b   Lobo, Suzana ^f   Dancer, Craig ^a   Rello, Jordi ^g   Dimopoulos, George ^h  

^a ROYAL BRISBANE AND WOMEN'S HOSPITAL   (Australia)

^b UNIVERSITY OF QUEENSLAND   (Australia)

^c GHENT UNIVERSITY HOSPITAL   (Belgium)

^d GHENT UNIVERSITY   (Belgium)

^e UNIVERSITY COLLEGE GHENT   (Belgium)

^f Instituto de Urologia e Nefrologia   (Brazil)

^g INSTITUTO DE SALUD CARLOS III   (Spain)

^h NATIONAL AND KAPODISTRIAN UNIVERSITY OF ATHENS   (Greece)

Author keywords

Candida; Epidemiology; Fungaemia; Intensive care; Mortality; Trends

Indexed keywords

AMPHOTERICIN; AMPHOTERICIN B; CASPOFUNGIN; CORTICOSTEROID; ECHINOCANDIN; FLUCONAZOLE; TERBINAFINE; VORICONAZOLE;

ADULT; AGED; ARTICLE; AUSTRALIA; BELGIUM; BLOOD CULTURE; BRAZIL; CANDIDA; CANDIDA ALBICANS; CANDIDA GLABRATA; CANDIDA KRUSEI; CANDIDA PARAPSILOSIS; CANDIDA TROPICALIS; CANDIDA ZEYLANOIDES; CANDIDEMIA; CENTRAL VENOUS CATHETER; CLINICAL EVALUATION; CLINICAL TRIAL; COHORT ANALYSIS; COMORBIDITY; CONTROLLED STUDY; DISEASE COURSE; DRUG SENSITIVITY; ECOLOGY; EPIDEMIOLOGICAL DATA; FEMALE; GEOGRAPHY; GREECE; HOSPITALIZATION; HUMAN; INTENSIVE CARE UNIT; MAJOR CLINICAL STUDY; MALE; MINIMUM INHIBITORY CONCENTRATION; MORTALITY; MULTICENTER STUDY; PARENTERAL NUTRITION; PRIORITY JOURNAL; RETROSPECTIVE STUDY; RISK FACTOR; TREATMENT OUTCOME;

EID: 64749108109     PISSN: 09248579     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijantimicag.2008.10.035     Document Type: Article

References (42)

1. Pappas P.G. Invasive candidiasis. Infect Dis Clin North Am 20 (2006) 485-506
2. Hobson R.P. The global epidemiology of invasive Candida infections-is the tide turning?. J Hosp Infect 55 (2003) 159-168
3. Coello R., Charlett A., Ward V., Wilson J., Pearson A., Sedgwick J., et al. Device-related sources of bacteraemia in English hospitals-opportunities for the prevention of hospital-acquired bacteraemia. J Hosp Infect 53 (2003) 46-57
4. Blumberg H.M., Jarvis W.R., Soucie J.M., Edwards J.E., Patterson J.E., Pfaller M.A., et al., National Epidemiology of Mycosis Survey (NEMIS) Study Group. Risk factors for candidal bloodstream infections in surgical intensive care unit patients: the NEMIS prospective multicenter study. National Epidemiology of Mycosis Survey. Clin Infect Dis 33 (2001) 177-186
5. Richards M.J., Edwards J.R., Culver D.H., and Gaynes R.P. Nosocomial infections in combined medical-surgical intensive care units in the United States. Infect Control Hosp Epidemiol 21 (2000) 510-515
6. Blot S.I., Vandewoude K.H., Hoste E.A., and Colardyn F.A. Effects of nosocomial candidemia on outcomes of critically ill patients. Am J Med 113 (2002) 480-485
7. Montravers P., Dupont H., Gauzit R., Veber B., Auboyer C., Blin P., et al. Candida as a risk factor for mortality in peritonitis. Crit Care Med 34 (2006) 646-652
8. Macphail G.L., Taylor G.D., Buchanan-Chell M., Ross C., Wilson S., and Kureishi A. Epidemiology, treatment and outcome of candidemia: a five-year review at three Canadian hospitals. Mycoses 45 (2002) 141-145
9. Cornwell III E.E., Belzberg H., Offne T.V., Dougherty W.R., Morales I.R., Asensio J., et al. The pattern of fungal infections in critically ill surgical patients. Am Surg 61 (1995) 847-850
10. Nolla-Salas J., Sitges-Serra A., León-Gil C., Martínez-González J., León-Regidor M.A., Ibáñez-Lucía P., et al., Study Group of Fungal Infection in the ICU. Candidemia in non-neutropenic critically ill patients: analysis of prognostic factors and assessment of systemic antifungal therapy. Intensive Care Med 23 (1997) 23-30
11. Eubanks P.J., de Virgilio C., Klein S., and Bongard F. Candida sepsis in surgical patients. Am J Surg 66 (1993) 617-619 [Discussion 619-20]
12. Voss A., le Noble J.L., Verduyn Lunel F.M., Foudraine N.A., and Meis J.F. Candidemia in intensive care unit patients: risk factors for mortality. Infection 25 (1997) 8-11
13. Ekenna O., Sherertz R.J., and Bingham H. Natural history of bloodstream infections in a burn patient population: the importance of candidemia. Am J Infect Control 21 (1993) 189-195
14. Blot S., Vandewoude K., Hoste E., Poelaert J., and Colardyn F. Outcome in critically ill patients with candidal fungaemia: Candida albicans vs. Candida glabrata. J Hosp Infect 47 (2001) 308-313
15. Pittet D., Tarara D., and Wenzel R.P. Nosocomial bloodstream infection in critically ill patients. Excess length of stay, extra costs, and attributable mortality. JAMA 271 (1994) 1598-1601
16. Morgan J., Meltzer M.I., Plikaytis B.D., Sofair A.N., Huie-White S., Wilcox S., et al. Excess mortality, hospital stay, and cost due to candidemia: a case-control study using data from population-based candidemia surveillance. Infect Control Hosp Epidemiol 26 (2005) 540-547 [Erratum in: Infect Control Hosp Epidemiol 2005;26:675]
17. Gudlaugsson O., Gillespie S., Lee K., Vande Berg J., Hu J., Messer S., et al. Attributable mortality of nosocomial candidemia, revisited. Clin Infect Dis 37 (2003) 1172-1177
18. Zaoutis T.E., Argon J., Chu J., Berlin J.A., Walsh T.J., and Feudtner C. The epidemiology and attributable outcomes of candidemia in adults and children hospitalized in the United States: a propensity analysis. Clin Infect Dis 41 (2005) 1232-1239
19. Leleu G., Aegerter P., and Guidet B. Systemic candidiasis in intensive care units: a multicenter, matched-cohort study. J Crit Care 17 (2002) 168-175
20. Parkins M.D., Sabuda D.M., Elsayed S., and Laupland K.B. Adequacy of empirical antifungal therapy and effect on outcome among patients with invasive Candida species infections. J Antimicrob Chemother 60 (2007) 613-618
21. Eggimann P., Garbino J., and Pittet D. Epidemiology of Candida species infections in critically ill non-immunosuppressed patients. Lancet Infect Dis 3 (2003) 685-702
22. Pfaller M.A., Pappas P.G., and Wingard J.R. Invasive fungal pathogens: current epidemiological trends. Clin Infect Dis 43 Suppl. 1 (2006) S3-S14
23. Blot S., and Vandewoude K. Management of invasive candidiasis in critically ill patients. Drugs 64 (2004) 2159-2175
24. Banerjee S.N., Emori T.G., Culver D.H., Gaynes R.P., Jarvis W.R., Horan T., et al. Secular trends in nosocomial primary bloodstream infections in the United States, 1980-1989. National Nosocomial Infections Surveillance System. Am J Med 91 (1991) 86S-89S
25. Trick W.E., Fridkin S.K., Edwards J.R., Hajjeh R.A., and Gaynes RP. National Nosocomial Infections Surveillance System Hospitals. Secular trend of hospital-acquired candidemia among intensive care unit patients in the United States during 1989-1999. Clin Infect Dis 35 (2002) 627-630
26. Bedini A., Venturelli C., Mussini C., Guaraldi G., Codeluppi M., Borghi V., et al. Epidemiology of candidaemia and antifungal susceptibility patterns in an Italian tertiary-care hospital. Clin Microbiol Infect 12 (2006) 75-80
27. Pfaller M.A., Diekema D.J., Jones R.N., Sader H.S., Fluit A.C., Hollis R.J., et al., SENTRY Participant Group. International surveillance of bloodstream infections due to Candida species: frequency of occurrence and in vitro susceptibilities to fluconazole, ravuconazole, and voriconazole of isolates collected from 1997 through 1999 in the SENTRY antimicrobial surveillance program. J Clin Microbiol 39 (2001) 3254-3259
28. Nucci M., Colombo A.L., Silveira F., Richtmann R., Salomão R., Branchini M.L., et al. Risk factors for death in patients with candidemia. Infect Control Hosp Epidemiol 19 (1998) 846-850
29. Eggimann P., Garbino J., and Pittet D. Management of Candida species infections in critically ill patients. Lancet Infect Dis 3 (2003) 772-785
30. Hope W., Morton A., and Eisen D.P. Increase in prevalence of nosocomial non-Candida albicans candidaemia and the association of Candida krusei with fluconazole use. J Hosp Infect 50 (2002) 56-65
31. Knaus W.A., Draper E.A., Wagner D.P., and Zimmerman J.E. APACHE II: a severity of disease classification system. Crit Care Med 13 (1985) 818-829
32. Messer S.A., Jones R.N., and Fritsche T.R. International surveillance of Candida spp. and Aspergillus spp.: report from the SENTRY Antimicrobial Surveillance Program (2003). J Clin Microbiol 44 (2006) 1782-1787
33. Diekema D.J., Messer S.A., Coffman S.A., Brueggemann A.B., Doern G.V., Herwaldt L.A., et al. The epidemiology of candidemia: Three year results from the Emerging Infections and the Epidemiology of Iowa Organisms study. J Clin Microbiol 40 (2002) 1298-1302
34. Blot S., Janssens R., Claeys G., Hoste E., Buyle F., De Waele J.J., et al. Effect of fluconazole consumption on long-term trends in candidal ecology. J Antimicrob Chemother 58 (2006) 474-477
35. Garbino J., Kolarova L., Rohner P., Lew D., Pichna P., and Pittet D. Secular trends of candidemia over 12 years in adult patients at a tertiary care hospital. Medicine (Baltimore) 81 (2002) 425-433
36. Charles P.E., Doise J.M., Quenot J.P., Aube H., Dalle F., Chavanet P., et al. Candidemia in critically ill patients: difference of outcome between medical and surgical patients. Intensive Care Med 29 (2003) 2162-2169
37. Shorr A.F., Lazarus D.R., Sherner J.H., Jackson W.L., Morrel M., Fraser V.J., et al. Do clinical features allow for accurate prediction of fungal pathogenesis in bloodstream infections? Potential implications of the increasing prevalence of non-albicans candidemia. Crit Care Med 35 (2007) 1077-1083
38. Dimopoulos G., Ntziora F., Rachiotis G., Armaganidis A., and Falagas M.E. Candida albicans versus non-albicans intensive care unit-acquired bloodstream infections: differences in risk factors and outcome. Anesth Analg 106 (2008) 523-529
39. Michalopoulos A.S., Geroulanos S., and Mentzelopoulos S.D. Determinants of candidemia and candidemia-related death in cardiothoracic ICU patients. Chest 124 (2003) 2244-2255
40. Pasqualotto A.C., Nedel W.L., Machado T.S., and Severo L.C. Risk factors and outcome for nosocomial breakthrough candidaemia. J Infect 52 (2006) 216-222
41. Chow J.K., Golan Y., Ruthazer R., Karchmer A.W., Carmeli Y., Lichtenberg D., et al. Factors associated with candidemia caused by non-albicans Candida species versus Candida albicans in the intensive care unit. Clin Infect Dis 46 (2008) 1206-1213
42. Slotman G.J., Shapiro E., and Moffa S.M. Fungal sepsis: multisite colonization versus fungemia. Am Surg 60 (1994) 107-113