The impact of plasma rich in growth factors on clinical and biological factors involved in healing processes after third molar extraction

Journal of Biomedical Materials Research - Part A

Volumn 95, Issue 3 A, 2010, Pages 741-746

  Mozzati, Marco ^a   Martinasso, Germana ^a   Pol, Renato ^a   Polastri, Carolina ^a   Cristiano, Antonio ^a   Muzio, Giuliana ^a   Canuto, Rosa ^a  

^a UNIVERSITY OF TURIN   (Italy)

Author keywords

BMP; Collagen; Cytokines; PRGF; Third molar

Indexed keywords

ANTI-INFLAMMATORIES; BIOLOGICAL FACTORS; BMP; CLINICAL EFFICACY; CONTROL SITES; CYTOKINES; GROWTH FACTOR; HEALING PROCESS; INTERLEUKIN1; KERATINOCYTES; PRGF; PROINFLAMMATORY CYTOKINES; SURGICAL PROCEDURES; THIRD MOLAR; TRANSFORMING GROWTH FACTORS; WOUND HEALING;

CELL CULTURE; COLLAGEN; ENZYME INHIBITION;

PEPTIDES;

AMOXICILLIN; ANTIINFLAMMATORY AGENT; GROWTH FACTOR; INTERLEUKIN 10; INTERLEUKIN 1BETA; INTERLEUKIN 6; NIMESULIDE; PLASMA RICH IN GROWTH FACTOR; TRANSFORMING GROWTH FACTOR BETA; UNCLASSIFIED DRUG;

ADULT; ARTICLE; CLINICAL ARTICLE; CLINICAL EVALUATION; CONTROLLED STUDY; DRUG EFFICACY; FACIAL SWELLING; FIBROBLAST; HUMAN; HUMAN TISSUE; KERATINOCYTE; MOLAR TOOTH; NUCLEOTIDE SEQUENCE; POSTOPERATIVE PAIN; SWELLING; TOOTH EXTRACTION; VISUAL ANALOG SCALE; WOUND HEALING;

ADOLESCENT; ADULT; ANIMALS; BIOLOGICAL FACTORS; HUMANS; INFLAMMATION; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; INTERLEUKIN-10; INTERLEUKIN-1BETA; INTERLEUKIN-6; MOLAR, THIRD; PAIN, POSTOPERATIVE; PLASMA; RANDOM ALLOCATION; TOOTH EXTRACTION; TRANSFORMING GROWTH FACTOR BETA; WOUND HEALING; YOUNG ADULT;

EID: 78249287798     PISSN: 15493296     EISSN: 15524965     Source Type: Journal    
DOI: 10.1002/jbm.a.32882     Document Type: Article

References (23)

1. Bui CH, Seldin EB, Dodson TB,. Types, frequencies, and risk factors for complications after third molar extraction. J Oral Maxillofac Surg 2003; 61: 1379 -1389.
2. Laureano Filho JR, Maurette PE, Allais M, Cotinho M, Fernandes C,. Clinical comparative study of the effectiveness of two dosages of dexamethasone to control postoperative swelling, trismus and pain after the surgical extraction of mandibular impacted third molars. Med Oral Patol Oral Cir Bucal 2008; 13: E129 -E132.
3. Beeman CS,. Third molar management: A case for routine removal in adolescent and young adult orthodontic patients. J Oral Maxillofac Surg 1999; 57: 824 -830.
4. Conrad SM, Blakey GH, Shugars DA, Marciani RD, Phillips C, White RP Jr,. Patients' perception of recovery after third molar surgery. J Oral Maxillofac Surg 1999; 57: 1288 -1294.
5. Kingsley CS,. Blood coagulation; evidence of an antagonist to factor VI in platelet-rich human plasma. Nature 1954; 173: 723 -724.
6. Tayapongsak P, O'Brien DA, Monteiro CB, Arcero-Dias LL,. Autologous fibrin adhesive in mandibular reconstruction with particulate cancellous bone and marrow. J Oral Maxillofac Surg 1994; 52: 161 -166.
7. Whitman DH, Berry RL, Green DM,. Platelet gel: An autologous alternative to fibrin glue with applications in oral and maxillofacial surgery. J Oral Maxillofac Surg 1997; 55: 1294 -1299.
8. Marx RE, Carlson ER, Eichstaedt RM, Schimmele SR, Strauss JE, Georgeff KR,. Platelet-rich plasma: Growth factor enhancement for bone grafts. Oral Surgery Oral Med Oral Pathol Oral Radiol Endod 1998; 85: 638 -646.
9. Sanchez AR, Eckert SE, Sheridan PJ, Weaver AL,. Influence of platelet-rich plasma added to xenogeneic bone grafts on bone mineral density associated with dental implants. Int J Oral Maxillofac Implants 2005; 20: 526 -532.
10. Anitua E,. Plasma rich in growth factors: Preliminary results of use in the preparation of future sites for implants. Int J Oral Maxillofac Implants 1999; 14: 529 -535.
11. Anitua E, Andia I, Ardanza B, Nurden P, Nurden AT,. Autologous platelets as a source of proteins for healing and tissue regeneration. Thromb Haemost 2004; 91: 4 -15.
12. Anitua E, Sanchez M, Nurden AT, Nurden P, Orive G, Andia I,. New insights into and novel applications for platelet-rich fibrin therapies. Trends Biotechnol 2006; 24: 227 -234.
13. Anitua E, Sanchez M, Orive G, Andia I,. The potential impact of the preparation rich in growth factors (PRGF) in different medical fields. Biomaterials 2007; 28: 4551 -4560.
14. Anitua E, Orive G, Pla R, Roman P, Serrano V, Andia I,. The effects of PRGF on bone regeneration and on titanium implant osseointegration in goats: A histologic and histomorphometric study. J Biomed Mater Res A 2009; 91: 158 -165.
15. Sanchez M, Anitua E, Azofra J, Aguirre JJ, Andia I,. Intra-articular injection of an autologous preparation rich in growth factors for the treatment of knee OA: A retrospective cohort study. Clin Exp Rheumatol 2008; 26: 910 -913.
16. Neupert EA III, Lee JW, Philput CB, Gordon JR,. Evaluation of dexamethasone for reduction of postsurgical sequelae of third molar removal. J Oral Maxillofac Surg 1992; 50: 1177 -1182.
17. Savin J, Ogden GR,. Third molar surgery-A preliminary report on aspects affecting quality of life in the early postoperative period. Br J Oral Maxillofac Surg 1997; 35: 246 -253.
18. Skjelbred P, Løkken P,. Post-operative pain and inflammatory reaction reduced by injection of a corticosteroid. A controlled trial in bilateral oral surgery. Eur J Clin Pharmacol 1982; 21: 391 -396.
19. Chang HC, Bistrian B,. The role of cytokines in the catabolic consequences of infection and injury. JPEN J Parenter Enteral Nutr 1998; 22: 156 -166.
20. Opal SM, DePalo VA,. Anti-inflammatory cytokines. Chest 2000; 117: 1162 -1172.
21. Werner S, Grose R,. Regulation of wound healing by growth factors and cytokines. Physiol Rev 2003; 83: 835 -870.
22. Price DD, McGrath PA, Rafii A, Buckingham B,. The validation of visual analogue scales as ratio scale measures for chronic and experimental pain. Pain 1983; 17: 45 -46.
23. Tavares MG, Machado AP, Motta BG, Borsatto MC, Rosa AL, Xavier SP,. Electro-acupuncture efficacy on pain control after mandibular third molar surgery. Braz Dent J 2007; 18: 158 -162.