The effects of PRGF on bone regeneration and on titanium implant osseointegration in goats: A histologic and histomorphometric study

Journal of Biomedical Materials Research - Part A

Volumn 91, Issue 1, 2009, Pages 158-165

  Anitua, Eduardo ^a   Orive, Gorka ^a   Pla, Rafael ^b   Roman, Pedro ^b   Serrano, Victoriano ^c   Andía, Isabel ^a  

^a Biotechnology Institute I MAS D   (Spain)

^b University Complutense of Madrid ^*

^c UNIVERSIDAD COMPLUTENSE DE MADRID   (Spain)

Author keywords

Bone regeneration; Dental implant; Growth factors; Histomorphometry; Osseointegration; Platelet activation

Indexed keywords

COLLAGEN; DENTAL PROSTHESES; LIQUIDS; MUSCULOSKELETAL SYSTEM; TISSUE REGENERATION; TITANIUM;

BONE REGENERATION; GROWTH FACTOR; HISTOMORPHOMETRY; OSSEOINTEGRATION; PLATELET ACTIVATION;

METAL IMPLANTS;

FIBRIN; GROWTH FACTOR; PREPARATION RICH IN GROWTH FACTORS; TISSUE SCAFFOLD; TITANIUM; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ARTICLE; BONE DEFECT; BONE REGENERATION; GOAT; HISTOLOGY; IMPLANT; MORPHOMETRICS; NONHUMAN; OSSIFICATION; TIBIA; TRABECULAR BONE;

EID: 70349137187     PISSN: 15493296     EISSN: 15524965     Source Type: Journal    
DOI: 10.1002/jbm.a.32217     Document Type: Article

References (39)

1. Werner S, Grose R. Regulation of wound healing by growth factors and cytokines. Physiol Rev 2003;83:835-870. (Pubitemid 36828927)
2. Lieberman JR, Daluiski A, Einhorn TA. The role of growth factors in the repair of the bone. Biology and clinical applications. J Bone Joint Surg Am 2002;84:1032-1044. (Pubitemid 34907256)
3. Luginbuehl V, Meinel L, Merkle HP, Gander B. Localized delivery of growth factors for bone repair. Eur J Pharm Biopharm 2004;58:197-208. (Pubitemid 39037229)
4. Anitua E, Andía I, Ardanza B, Nurden P, Nudern AT. Autologous platelets as a source of proteins for healing and tissue regeneration. Thromb Haemost 2004;91:4-15. (Pubitemid 38111215)
5. Anitua E. Plasma rich in growth factors: Preliminary results of the use in the preparation of future sites for implants. Int J Oral Maxillofac Implants 1999;14:529-535.
6. Marx RE, Carlson ER, Eichstaedt RN, Schimmele SR, Strauss JE, Georgeff KR. Platelet-rich plasma: Growth factor enhancement for bone grafts. Oral Surg Oral Med Oral Pathol Oral Radiol Endodon 1998;85:638-646.
7. Lucarelli E, Beccheroni A, Donati D, Sangiorgi L, Cenacchi A, Del Vento AM, Meottid C, Bertojaa AZ, Giardinoe R, Fornasaric PM, Mercurib M, Piccia P. Platelet-derived growth factors enhance proliferation of human stromal stem cells. Biomaterials 2003;24:3095-3100. (Pubitemid 36944940)
8. Leitner GC, Gruber R, Neunüller J, Wagner A, Kloimstein P, Höcker P, Körmöczi GF, Buchta C. Platelet content and growth factor release in platelet rich plasma: A comparison of four different systems. Vox Sanguinis 2006;91:135-139. (Pubitemid 44126609)
9. Cochran DL. The evidence for immediate loading of implants. J Evid Base Dent Pract 2006;6:155-163.
10. Anitua E, Sánchez M, Nurden AT, Nurden P, Orive G, Andía I. New insights into and novel applications for platelet-rich fibrin therapies. Trends Biotechnol 2006;5:227-234.
11. Aghaloo TL, Moy PK, Freymiller EG. Evaluation of platelet rich plasma in combination with anorganic bovine bone in the rabbit cranium: A pilot study. Int J Oral Maxillofac Implants 2004;19:59-65.
12. Plachakova AS, van der Dolder J, Stoelinga PJ, Jansen JA. The bone regenerative effects of platelet rich plasma in combination with an osteoconductive materials in rat cranial defects. Clin Oral Implant Res 2006;17:305-311.
13. Anitua E, Sanchez M, Nurden AT, Zalduendo M, de la Fuente M, Orive G, Azofra J, Andía I. Autologous fibrin matrices: A potential source of biological mediators that modulate tendon cell activities. J Biomed Mater Res A 2006;77:285-293. (Pubitemid 47233530)
14. Anitua E, Sánchez M, Orive G, Andía I. The potential impact of the preparation rich in growth factors (PRGF) in different medical fields. Biomaterials 2007;28:4551-4560. (Pubitemid 47271893)
15. Adell R, Lekholm U, Grøndahl K, Brånemarrk PI, Lindstrøm J, Jacobsen M. Reconstruction of severely resorbed edentulous maxillae using osseointegrated fixtures in immediate autogenous bone grafts. Int J Oral Maxilof Implants 1990;5:233-246.
16. Schropp L, Wenzel A, Kostopoulus L, Karring T. Bone healing and soft issue contour changes following single-tooth extraction: A clinical and radiographic 12-month prospective study. Int J Periodont Restor Dent 2003;23:313-323. (Pubitemid 37162313)
17. Landesberg R, Moses M, Karpatkin M. Risk of using platelet-rich plasma gel. J Oral Maxillofac Surg 1998;56:1116-1117. (Pubitemid 28406604)
18. Tsay RC, Vo J, Burke A, Eisig SB, Lu HH, Landesberg R. Differential growth factor retention by platelet rich plasma composites. J Oral Maxillofac Surg 2005;63:521-528. (Pubitemid 40409850)
19. Schnabel LV, Mohammed HO, Miller BJ, McDermott WG, Jacobson MS, Santangelo KS, Fortier LA. Platelet rich plasma (PRP) enhances anabolic gene expression patterns in flexor digitorum superficialis tendons. J Orthop Res 2007;25:230-240.
20. Anitua E, Andía I, Sánchez M, Azofra J, Zalduendo M, De la Fuente M, Nurden P, Nurden AT. Autologous preparations rich in growth factors promote proliferation and induce VEGF and HGF production by human tendon cells in culture. J Orthop Res 2005;23:281-286. (Pubitemid 40287850)
21. Anitua E, Sanchez M, Nurden AT, Zalduendo M, de la Fuente M, Azofra J, Andia I. Reciprocal actions of platelet-secreted TGF-b1 on the production of VEGF and HGF by human tendon cells. Plast Reconstruct Surg 2007;119:950-959. (Pubitemid 46302852)
22. Graves DT, Valentin-Opran A, Delgado R, Valente AJ, Mundy G, Piche J. The potential role of platelet derived growth factor as an autocrine or paracrine factor for human bone cells. Connect Tissue Res 1989;23:209-218.
23. Maeda S, Hayasi M, Komiya S, Imamura T, Miyazono K. Endogenous TGF-beta signalling suppresses maturation of osteoblastic mesenchymal cells. EMBO J 2004;23:552-563. (Pubitemid 38282387)
24. Ferrara N, Gerber HP, LeCouter J. The biology of VEGF and its receptors. Nat Med 2003;9:669-676.
25. Suba Z, Takacs D, Gyulai-Gaál S, Kovacs K. Facilitation of β-tricalcium phosphate induced alveolar bone regeneration by platelet rich plasma in beagle dogs: A histologic and histomorphometric study. Int J Oral Maxillofac Implants 2004;19:832-838. (Pubitemid 40081666)
26. Sanchéz M, Azofra J, Anitua E, Andía I, Padilla S, Santisteban J, Mujika I. Enhancement of osseointegration by generating a dynamic implant surface. Med Sci Sports Exer 2003;35:1648-1652.
27. Anitua E, Sanchez M, Nurden AT, Zalduendo M, de la Fuente M, Orive G, Azofra J, Andía I. Autologous fibrin matrices: A potencial source of biological mediators that modulate tendon cell activities. J Biomed Mater Res 2006;77:285-293. (Pubitemid 47233530)
28. Rompen E, Domken O, Degidi M, Pontes AEF, Piattelli A. The effect of material characteristics, of surface topography and of implant components and connections on sift tissue integration: A literature review. Clin Oral Implant Res 2006;17:55-67. (Pubitemid 44327698)
29. Thor A, Rasmusson L, Wennerberg A, Thomsen P, Hirsch J-M, Nilsson B, Hong J. The role of whole blood in thrombin generation in contact with various titanium surfaces. Biomaterials 2007;28:966-974. (Pubitemid 44809427)
30. Gruber R, Varga F, Fischer MB, Watzek G. Platelets stimulate proliferation of bone cells: Involvement of platelet-derived growth factor, microparticles and membranes. Clin Oral Implants Res 2002;13:529-535. (Pubitemid 41713080)
31. Weibrich G, Gnoth SH, Otto M, Reichert T, Wagner W. Stimulation of the proliferation rate of human osteoblast like cells by platelet concentrates in vitro. Mund Kiefer Gesichtschir 2002;6:168-174.
32. Doucet C, Ernou I, Zhang Y, Llense JR, Begot L, Holy X, Lataillade JJ. Platelet lysates promote mesenchymal stem cell expansion: A safety substitute for animal serum in cell-based therapy applications. J Cell Physiol 2005;9999:1-9. (Pubitemid 41428905)
33. Celotti F, Colciago A, Negri-Cesi P, Pravettoni A, Zaninetti R, Sacchi MC. Effect of platelet-rich plasma on migration and proliferation of SaOS-2 osteoblasts: Role of platelet-derived growth factor and transforming growth factor-β. Wound Rep Reg 2006;14:195-202.
34. Ye L, Peng L, Tan H, Zhou X. HGF enhanced proliferation and differentiation of dental pulp cells. J Endod 2006;32:736-741. (Pubitemid 44067215)
35. Dean JW, Culbertson KC, D'Angelo AM. Fibronectin and laminin enhance gingival cell attachment to dental implant surfaces in vitro. Int J Maxillofac Implants 1995;10:721-728.
36. Schneider G, Burridge K. Formation of focal adhesions by osteoblasts adhering to different substrata. Exp Cell Res 1994;214:264-269. (Pubitemid 24302401)
37. Scheideler L, Geis-Gerstorfer J, Kern D, Pfeiffer F, Rupp F, Weber H, Wolburg H. Investigation of cell reactions to microstructured implant surfaces. Mater Sci Eng C 2003;23:455-459. (Pubitemid 36211443)
38. Fuerst G, Gruber R, Tangl S, Sanroman F, Watzek G. Enhanced bone-to-implant contact by platelet-released growth factors in mandibular cortical bone: A histomorphometric study in minipigs. Int J Maxillofac Implants 2003;18:685-690. (Pubitemid 37281815)
39. Nikolidakis D, Van den Dolder J, Wolke JGC, Stoelinga PJW, Jansen JA. The seffect of plastelet-rich plasma on the bone healing around calcium phosphate-coated and non-coated oral implants in trabecular bone. Tissue Eng 2006;12:1-9. (Pubitemid 46141278)