Effect of endothelial nitric oxide synthase on epidermal permeability barrier recovery after disruption

British Journal of Dermatology

Volumn 163, Issue 5, 2010, Pages 915-919

  Ikeyama, K ^a   Denda, M ^a  

^a SHISEIDO RESEARCH CENTER   (Japan)

Author keywords

Barrier disruption; Epidermis; Nitric oxide; Nitric oxide synthase

Indexed keywords

ACETONE; ENDOTHELIAL NITRIC OXIDE SYNTHASE; INDUCIBLE NITRIC OXIDE SYNTHASE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; CONVALESCENCE; ELECTRON MICROSCOPY; EPIDERMIS; HOMEOSTASIS; IMMUNOHISTOCHEMISTRY; IMMUNOREACTIVITY; KNOCKOUT MOUSE; LAMELLAR BODY; MALE; MOUSE; NONHUMAN; OBSERVATION; PERMEABILITY BARRIER; PRIORITY JOURNAL; WILD TYPE;

ACETONE; ANIMALS; EPIDERMIS; IMMUNOHISTOCHEMISTRY; MICE; MICE, KNOCKOUT; MICROSCOPY, ELECTRON; NITRIC OXIDE SYNTHASE TYPE II; NITRIC OXIDE SYNTHASE TYPE III; PERMEABILITY; WATER LOSS, INSENSIBLE;

EID: 78249287550     PISSN: 00070963     EISSN: 13652133     Source Type: Journal    
DOI: 10.1111/j.1365-2133.2010.09945.x     Document Type: Article

References (18)

1. Bruch-Gerharz D, Ruzicka T, Kolb-Bachofen V,. Nitric oxide in human skin: current status and future prospects. J Invest Dermatol 1998; 110: 1 -7.
2. Cals-Grierson MM, Ormerod AD,. Nitric oxide function in the skin. Nitric Oxide 2004; 10: 179 -93.
3. Weller R,. Nitric oxide: a key mediator in cutaneous physiology. Clin Exp Dermatol 2003; 28: 511 -14.
4. Ikeyama K, Fuziwara S, Denda M,. Topical application of neuronal nitric oxide synthase inhibitor accelerates cutaneous barrier recovery and prevents epidermal hyperplasia induced by barrier disruption. J Invest Dermatol 2007; 127: 1713 -19.
5. Ikeyama K, Denda S, Tsutsumi M, Denda M,. Neuronal nitric oxide synthase in epidermis is involved in cutaneous circulatory response to mechanical stimulation. J Invest Dermatol 2010; 130: 1158 -66.
6. Denda M, Sato J, Masuda Y, et al. Exposure to a dry environment enhances epidermal permeability barrier function. J Invest Dermatol 1998; 111: 858 -63.
7. Denda M, Tsuchiya T,. Barrier recovery rate varies time-dependently in human skin. Br J Dermatol 2000; 142: 881 -4.
8. Wood LC, Jackson SM, Elias PM, et al. Cutaneous barrier perturbation stimulates cytokine production in the epidermis of mice. J Clin Invest 1992; 90: 482 -7.
9. Arany I, Brysk MM, Brysk H, Tyring SK,. Regulation of inducible nitric oxide synthase mRNA levels by differentiation and cytokines in human keratinocytes. Biochem Biophys Res Commun 1996; 220: 618 -22.
10. Sirsjo A, Karlsson M, Gidlof A, et al. Increased expression of inducible nitric oxide synthase in psoriatic skin and cytokine-stimulated cultured keratinocytes. Br J Dermatol 1996; 134: 643 -8.
11. Ormerod AD, Weller R, Copeland P, et al. Detection of nitric oxide and nitric oxide synthases in psoriasis. Arch Dermatol Res 1998; 290: 3 -8.
12. Denda M, Fuziwara S, Inoue K,. Influx of calcium and chloride ions into epidermal keratinocytes regulates exocytosis of epidermal lamellar bodies and skin permeability barrier homeostasis. J Invest Dermatol 2003; 121: 362 -7.
13. Denda M, Fuziwara S, Hibino T,. Expression of voltage-gated calcium channel subunit aC1 in epidermal keratinocytes and effects of agonist and antagonists of the channel on skin barrier homeostasis. Exp Dermatol 2006; 15: 455 -60.
14. Morishita T, Tsutsui M, Shimokawa H, et al. Vasculoprotective roles of neuronal nitric oxide synthase. FASEB J 2002; 16: 1994 -6.
15. Meng W, Ma J, Ayata C, et al. ACh dilates pial arterioles in endothelial and neuronal NOS knockout mice by NO-dependent mechanisms. Am J Physiol 1996; 271: H1145 -50.
16. Huang A, Sun D, Shesely EG, et al. Neuronal NOS-dependent dilation to flow in coronary arteries of male eNOS-KO mice. Am J Physiol Heart Circ Physiol 2002; 282: H429 -36.
17. Meng W, Ayata C, Waeber C, et al. Neuronal NOS-cGMP-dependent ACh-induced relaxation in pial arterioles of endothelial NOS knockout mice. Am J Physiol 1998; 274: H411 -15.
18. Denda M, Nakatani M, Ikeyama K, et al. Epidermal keratinocytes as the forefront of the sensory system. Exp Dermatol 2007; 16: 157 -61.