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Volumn 32, Issue 10, 2010, Pages 1211-1221

Meta-analysis: Insulin sensitizers for the treatment of non-alcoholic steatohepatitis

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA TOCOPHEROL; INSULIN SENSITIZING AGENT; METFORMIN; PIOGLITAZONE; ROSIGLITAZONE;

EID: 78249262957     PISSN: 02692813     EISSN: 13652036     Source Type: Journal    
DOI: 10.1111/j.1365-2036.2010.04467.x     Document Type: Article
Times cited : (144)

References (44)
  • 1
    • 0033982172 scopus 로고    scopus 로고
    • Prevalence of and risk factors for hepatic steatosis in northern Italy
    • Bellentani S, Saccoccio G, Masutti F, et al. Prevalence of and risk factors for hepatic steatosis in northern Italy. Ann Intern Med 2000; 132: 112-7.
    • (2000) Ann Intern Med , vol.132 , pp. 112-117
    • Bellentani, S.1    Saccoccio, G.2    Masutti, F.3
  • 2
    • 77954424925 scopus 로고    scopus 로고
    • Nonalcoholic fatty liver disease increases risk of death among patients with diabetes: A community-based cohort study
    • Adams LA, Harmsen S, St Sauver JL, et al. Nonalcoholic fatty liver disease increases risk of death among patients with diabetes: a community-based cohort study. Am J Gastroenterol 2010; 105: 1567-73.
    • (2010) Am J Gastroenterol , vol.105 , pp. 1567-1573
    • Adams, L.A.1    Harmsen, S.2    St Sauver, J.L.3
  • 4
    • 4344629376 scopus 로고    scopus 로고
    • Nonalcoholic fatty liver disease in individuals with severe obesity
    • Haynes P, Liangpunsakul S, Chalasani N,. Nonalcoholic fatty liver disease in individuals with severe obesity. Clin Liver Dis 2004; 8: 535-47.
    • (2004) Clin Liver Dis , vol.8 , pp. 535-547
    • Haynes, P.1    Liangpunsakul, S.2    Chalasani, N.3
  • 5
    • 33750606061 scopus 로고    scopus 로고
    • Long-term follow-up of patients with NAFLD and elevated liver enzymes
    • Ekstedt M, Franzãn LE, Mathiesen UL, et al. Long-term follow-up of patients with NAFLD and elevated liver enzymes. Hepatology 2006; 44: 865-73.
    • (2006) Hepatology , vol.44 , pp. 865-873
    • Ekstedt, M.1    Franzãn, L.E.2    Mathiesen, U.L.3
  • 6
    • 50549084740 scopus 로고    scopus 로고
    • Increased overall mortality and liver-related mortality in non-alcoholic fatty liver disease
    • Ong JP, Pitts A, Younossi ZM,. Increased overall mortality and liver-related mortality in non-alcoholic fatty liver disease. J Hepatol 2008; 49: 608-12.
    • (2008) J Hepatol , vol.49 , pp. 608-612
    • Ong, J.P.1    Pitts, A.2    Younossi, Z.M.3
  • 7
    • 67651173053 scopus 로고    scopus 로고
    • Non-alcoholic fatty liver disease is associated with cardiovascular disease risk markers
    • Edens MA, Kuipers F, Stolk RP,. Non-alcoholic fatty liver disease is associated with cardiovascular disease risk markers. Obesity reviews 2009; 10: 412-9.
    • (2009) Obesity Reviews , vol.10 , pp. 412-419
    • Edens, M.A.1    Kuipers, F.2    Stolk, R.P.3
  • 8
    • 58149378359 scopus 로고    scopus 로고
    • Association between non-alcoholic fatty lvier disease and cardiovascular disease: A first message should pass
    • Picardi A, Vespasiani-Gentilucci U,. Association between non-alcoholic fatty lvier disease and cardiovascular disease: a first message should pass. Am J Gastroenterol 2008; 103: 3036-8.
    • (2008) Am J Gastroenterol , vol.103 , pp. 3036-3038
    • Picardi, A.1    Vespasiani-Gentilucci, U.2
  • 9
    • 66749106254 scopus 로고    scopus 로고
    • Epidemiology and natural history of non-alcoholic fatty liver disease (NAFLD)
    • Bellentani S, Marino M,. Epidemiology and natural history of non-alcoholic fatty liver disease (NAFLD). Ann Hepatol 2009; 8 (Suppl 1): S4-8.
    • (2009) Ann Hepatol , vol.8 , Issue.SUPPL. 1 , pp. 4-8
    • Bellentani, S.1    Marino, M.2
  • 10
    • 70349758229 scopus 로고    scopus 로고
    • Pharmacologic therapy of non-alcoholic steatohepatitis
    • Ratziu V, Zelber-Sagi S,. Pharmacologic therapy of non-alcoholic steatohepatitis. Clin Liver Dis 2009; 13: 667-88.
    • (2009) Clin Liver Dis , vol.13 , pp. 667-688
    • Ratziu, V.1    Zelber-Sagi, S.2
  • 11
    • 73449116035 scopus 로고    scopus 로고
    • Randomized controlled trial testing the effects of weight loss on nonalcoholic steatohepatitis (NASH)
    • Promrat K, Kleiner DE, Niemeier HM, et al. Randomized controlled trial testing the effects of weight loss on nonalcoholic steatohepatitis (NASH). Hepatology 2010; 51: 121-9.
    • (2010) Hepatology , vol.51 , pp. 121-129
    • Promrat, K.1    Kleiner, D.E.2    Niemeier, H.M.3
  • 12
    • 19144372447 scopus 로고    scopus 로고
    • One-year intense nutritional counseling results in histological improvement in patients with non-alcoholic steatohepatitis: A pilot study
    • Huang MA, Greenson JK, Chao C, et al. One-year intense nutritional counseling results in histological improvement in patients with non-alcoholic steatohepatitis: a pilot study. Am J Gastroenterol 2005; 100: 1072-81.
    • (2005) Am J Gastroenterol , vol.100 , pp. 1072-1081
    • Huang, M.A.1    Greenson, J.K.2    Chao, C.3
  • 13
    • 70349764468 scopus 로고    scopus 로고
    • Role of insulin resistance and lipotoxicity in non-alcoholic steatohepatitis
    • Cusi K,. Role of insulin resistance and lipotoxicity in non-alcoholic steatohepatitis. Clin Liver Dis 2009; 13: 545-63.
    • (2009) Clin Liver Dis , vol.13 , pp. 545-663
    • Cusi, K.1
  • 14
    • 48649110854 scopus 로고    scopus 로고
    • The role of fatty acids in the development and progression of nonalcoholic fatty liver disease
    • Gentile CL, Pagliassotti MJ,. The role of fatty acids in the development and progression of nonalcoholic fatty liver disease. J Nutr Biochem 2008; 19: 567-76.
    • (2008) J Nutr Biochem , vol.19 , pp. 567-576
    • Gentile, C.L.1    Pagliassotti, M.J.2
  • 15
    • 48449103834 scopus 로고    scopus 로고
    • Review article: Diagnosis and treatment of non-alcoholic fatty liver disease
    • Oh MK, Winn J, Poordad F,. Review article: diagnosis and treatment of non-alcoholic fatty liver disease. Aliment Pharmacol Ther 2008; 28: 503-22.
    • (2008) Aliment Pharmacol Ther , vol.28 , pp. 503-522
    • Oh, M.K.1    Winn, J.2    Poordad, F.3
  • 16
    • 77649337140 scopus 로고    scopus 로고
    • Nonalcoholic fatty liver disease: Pathology and pathogenesis
    • Tiniakos DG, Vos MB, Brunt EM,. Nonalcoholic fatty liver disease: pathology and pathogenesis. Annu Rev Pathol 2010; 5: 145-71.
    • (2010) Annu Rev Pathol , vol.5 , pp. 145-171
    • Tiniakos, D.G.1    Vos, M.B.2    Brunt, E.M.3
  • 17
    • 0033927667 scopus 로고    scopus 로고
    • Cellular mechanisms of insulin resistance
    • Shulman GI,. Cellular mechanisms of insulin resistance. J Clin Invest 2000; 106: 171-6.
    • (2000) J Clin Invest , vol.106 , pp. 171-176
    • Shulman, G.I.1
  • 18
    • 68849113147 scopus 로고    scopus 로고
    • Medications for obesity: Mechanisms and applications
    • Bray GA,. Medications for obesity: mechanisms and applications. Clin Chest Med 2009; 30: 525-38.
    • (2009) Clin Chest Med , vol.30 , pp. 525-538
    • Bray, G.A.1
  • 20
    • 0026776749 scopus 로고
    • Variance imputation for overviews of clinical trials with continuous response
    • Follmann D, Elliott P, Suh I, Cutler J,. Variance imputation for overviews of clinical trials with continuous response. J Clin Epidemiol 1992; 45: 769-73.
    • (1992) J Clin Epidemiol , vol.45 , pp. 769-773
    • Follmann, D.1    Elliott, P.2    Suh, I.3    Cutler, J.4
  • 21
    • 41049093347 scopus 로고
    • The combination of estimated from different experiments
    • Cochran W,. The combination of estimated from different experiments. Biometrics 1954; 10: 101-29.
    • (1954) Biometrics , vol.10 , pp. 101-129
    • Cochran, W.1
  • 22
    • 0037098199 scopus 로고    scopus 로고
    • Quantifying heterogeneity in a meta-analysis
    • Higgins JPT, Thompson SG,. Quantifying heterogeneity in a meta-analysis. Statist Med 2002; 21: 1539-58.
    • (2002) Statist Med , vol.21 , pp. 1539-1558
    • Higgins, J.P.T.1    Thompson, S.G.2
  • 23
    • 0000976601 scopus 로고    scopus 로고
    • Meta-analysis, funnel plots and sensitivity analysis
    • Copas J, Shi JQ,. Meta-analysis, funnel plots and sensitivity analysis. Biostatistics 2000; 1: 247-62.
    • (2000) Biostatistics , vol.1 , pp. 247-262
    • Copas, J.1    Shi, J.Q.2
  • 24
    • 0030922816 scopus 로고    scopus 로고
    • Bias in meta-analysis detected by a simple graphical test
    • Egger M, Davey Smith G, Schneider M, Minder C,. Bias in meta-analysis detected by a simple graphical test. BMJ 1996; 315: 629-34.
    • (1996) BMJ , vol.315 , pp. 629-634
    • Egger, M.1    Davey Smith, G.2    Schneider, M.3    Minder, C.4
  • 25
    • 77951874018 scopus 로고    scopus 로고
    • Pioglitazone, vitamin E, or placebo for nonalcoholic steatohepatitis
    • Sanyal AJ, Chalasani N, Kowdley KV, et al. Pioglitazone, vitamin E, or placebo for nonalcoholic steatohepatitis. New Engl J Med 2010; 362: 1675-85.
    • (2010) New Engl J Med , vol.362 , pp. 1675-1685
    • Sanyal, A.J.1    Chalasani, N.2    Kowdley, K.V.3
  • 26
    • 14944359845 scopus 로고    scopus 로고
    • A pilot study of vitamin e versus vitamin e and pioglitazone for the treatment of nonalcoholic steatohepatitis
    • Sanyal AJ, Mofrad PS, Contos MJ, et al. A pilot study of vitamin E versus vitamin E and pioglitazone for the treatment of nonalcoholic steatohepatitis. Clin Gastroenterol Hepatol 2004; 2: 1107-15.
    • (2004) Clin Gastroenterol Hepatol , vol.2 , pp. 1107-1115
    • Sanyal, A.J.1    Mofrad, P.S.2    Contos, M.J.3
  • 27
    • 53049101877 scopus 로고    scopus 로고
    • Randomized, placebo-controlled trial of pioglitazone in nondiabetic subjects with nonalcoholic steatohepatitis
    • Aithal GP, Thomas JA, Kaye PV, et al. Randomized, placebo-controlled trial of pioglitazone in nondiabetic subjects with nonalcoholic steatohepatitis. Gastroenterology 2008; 135: 1176-84.
    • (2008) Gastroenterology , vol.135 , pp. 1176-1184
    • Aithal, G.P.1    Thomas, J.A.2    Kaye, P.V.3
  • 28
    • 33751545838 scopus 로고    scopus 로고
    • A placebo-controlled trial of pioglitazone in subjects with nonalcoholic steatohepatitis
    • Belfort R, Harrison SA, Brown K, et al. A placebo-controlled trial of pioglitazone in subjects with nonalcoholic steatohepatitis. N Engl J Med 2006; 355: 2297-307.
    • (2006) N Engl J Med , vol.355 , pp. 2297-2307
    • Belfort, R.1    Harrison, S.A.2    Brown, K.3
  • 29
    • 46349088361 scopus 로고    scopus 로고
    • Rosiglitazone for nonalcoholic steatohepatitis: One-year results of the randomized placebo-controlled Fatty Liver Improvement with Rosiglitazone Therapy (FLIRT) Trial
    • Ratziu V, Giral P, Jacqueminet S, et al. Rosiglitazone for nonalcoholic steatohepatitis: one-year results of the randomized placebo-controlled Fatty Liver Improvement with Rosiglitazone Therapy (FLIRT) Trial. Gastroenterology 2008; 135: 100-10.
    • (2008) Gastroenterology , vol.135 , pp. 100-110
    • Ratziu, V.1    Giral, P.2    Jacqueminet, S.3
  • 30
    • 45549091794 scopus 로고    scopus 로고
    • Clinical trial: Insulin-sensitizing agents may reduce consequences of insulin resistance in individuals with non-alcoholic steatohepatitis
    • Idilman R, Mizrak D, Corapcioglu D, et al. Clinical trial: insulin-sensitizing agents may reduce consequences of insulin resistance in individuals with non-alcoholic steatohepatitis. Aliment Pharmacol Ther 2008; 28: 200-8.
    • (2008) Aliment Pharmacol Ther , vol.28 , pp. 200-208
    • Idilman, R.1    Mizrak, D.2    Corapcioglu, D.3
  • 31
    • 77953368192 scopus 로고    scopus 로고
    • The effect of metformin and standard therapy versus standard therapy alone in nondiabetic patients with insulin resistance and nonalcoholic steatohepatitis (NASH): A pilot study
    • Shields WW, Thompson KE, Grice GA, Harrison SA, Coyle WJ,. The effect of metformin and standard therapy versus standard therapy alone in nondiabetic patients with insulin resistance and nonalcoholic steatohepatitis (NASH): a pilot study. Therap Adv Gastroenterol 2009; 2: 157-63.
    • (2009) Therap Adv Gastroenterol , vol.2 , pp. 157-163
    • Shields, W.W.1    Thompson, K.E.2    Grice, G.A.3    Harrison, S.A.4    Coyle, W.J.5
  • 32
    • 1642296465 scopus 로고    scopus 로고
    • Metformin in the treatment of patients with non-alcoholic steatohepatitis
    • Uygun A, Kadayifci A, Isik AT, et al. Metformin in the treatment of patients with non-alcoholic steatohepatitis. Aliment Pharmacol Ther 2004; 19: 537-44.
    • (2004) Aliment Pharmacol Ther , vol.19 , pp. 537-544
    • Uygun, A.1    Kadayifci, A.2    Isik, A.T.3
  • 33
    • 70350662659 scopus 로고    scopus 로고
    • Metformin in patients with non-alcoholic fatty liver disease: A randomized, controlled trial
    • Haukeland JW, Konopski Z, Eggesbã HB, et al. Metformin in patients with non-alcoholic fatty liver disease: a randomized, controlled trial. Scand J Gastroenterol 2009; 44: 853-60.
    • (2009) Scand J Gastroenterol , vol.44 , pp. 853-860
    • Haukeland, J.W.1    Konopski, Z.2    Eggesbã, H.B.3
  • 35
    • 77951601655 scopus 로고    scopus 로고
    • Thiazolidinedione drugs and cardiovascular risks: A science advisory from the American Heart Association and American College of Cardiology Foundation
    • Kaul S, Bolger AF, Herrington D, Giugliano RP, Eckel RH,. Thiazolidinedione drugs and cardiovascular risks: a science advisory from the American Heart Association and American College of Cardiology Foundation. Circulation 2010; 121: 1868-77.
    • (2010) Circulation , vol.121 , pp. 1868-1877
    • Kaul, S.1    Bolger, A.F.2    Herrington, D.3    Giugliano, R.P.4    Eckel, R.H.5
  • 36
    • 34548306770 scopus 로고    scopus 로고
    • The effects of discontinuing pioglitazone in patients with nonalcoholic steatohepatitis
    • Lutchman G, Modi A, Kleiner DE, et al. The effects of discontinuing pioglitazone in patients with nonalcoholic steatohepatitis. Hepatology 2007; 46: 424-9.
    • (2007) Hepatology , vol.46 , pp. 424-429
    • Lutchman, G.1    Modi, A.2    Kleiner, D.E.3
  • 37
    • 75449116707 scopus 로고    scopus 로고
    • Long-term efficacy of rosiglitazone in nonalcoholic steatohepatitis: Results of the fatty liver improvement by rosiglitazone therapy (FLIRT 2) extension trial
    • Ratziu V, Charlotte F, Bernhardt C, et al. Long-term efficacy of rosiglitazone in nonalcoholic steatohepatitis: results of the fatty liver improvement by rosiglitazone therapy (FLIRT 2) extension trial. Hepatology 2010; 51: 445-53.
    • (2010) Hepatology , vol.51 , pp. 445-453
    • Ratziu, V.1    Charlotte, F.2    Bernhardt, C.3
  • 38
    • 33748748206 scopus 로고    scopus 로고
    • Effect of rosiglitazone on the frequency of diabetes in patients with impaired glucose tolerance or impaired fasting glucose: A randomised controlled trial
    • DREAM (Diabetes REduction Assessment with ramipril and rosiglitazone Medication) Trial Investigators, et al.;:-105.
    • DREAM (Diabetes REduction Assessment with ramipril and rosiglitazone Medication) Trial Investigators, Gerstein HC, Yusuf S, et al. Effect of rosiglitazone on the frequency of diabetes in patients with impaired glucose tolerance or impaired fasting glucose: a randomised controlled trial. Lancet 2006; 368: 1096-105.
    • (2006) Lancet , vol.368 , pp. 1096
    • Gerstein, H.C.1    Yusuf, S.2
  • 39
    • 3042685448 scopus 로고    scopus 로고
    • Thiazolidinedione therapy in the preventin.delay of type 2 diabetes in patients with impaired glucose tolerance and insulin resistance
    • Durbin RJ,. Thiazolidinedione therapy in the preventin.delay of type 2 diabetes in patients with impaired glucose tolerance and insulin resistance. Diabetes Obes Metab 2004; 6: 280-5.
    • (2004) Diabetes Obes Metab , vol.6 , pp. 280-285
    • Durbin, R.J.1
  • 40
    • 0036724346 scopus 로고    scopus 로고
    • Preservation of pancreatic beta-cell function and prevention of type 2 diabetes by pharmacological treatment of insulin resistance in high-risk hispanic women
    • Buchanan TA, Xiang AH, Peters RK, et al. Preservation of pancreatic beta-cell function and prevention of type 2 diabetes by pharmacological treatment of insulin resistance in high-risk hispanic women. Diabetes 2002; 51: 2796-803.
    • (2002) Diabetes , vol.51 , pp. 2796-2803
    • Buchanan, T.A.1    Xiang, A.H.2    Peters, R.K.3
  • 41
    • 0033855572 scopus 로고    scopus 로고
    • Ligands of peroxisome proliferator-activated receptor gamma modulate profibrogenic and proinflammatory actions in hepatic stellate cells
    • Marra F, Efsen E, Romanelli RG, et al. Ligands of peroxisome proliferator-activated receptor gamma modulate profibrogenic and proinflammatory actions in hepatic stellate cells. Gastroenterology 2000; 119: 466-78.
    • (2000) Gastroenterology , vol.119 , pp. 466-478
    • Marra, F.1    Efsen, E.2    Romanelli, R.G.3
  • 42
    • 2942655390 scopus 로고    scopus 로고
    • Evidence for a potent anti-inflammatory effect of rosiglitazone
    • Mohanty P, Aljada A, Ghanim H, et al. Evidence for a potent anti-inflammatory effect of rosiglitazone. J Clin Endocrinol Metab 2004; 89: 2728-35.
    • (2004) J Clin Endocrinol Metab , vol.89 , pp. 2728-2735
    • Mohanty, P.1    Aljada, A.2    Ghanim, H.3
  • 43
    • 0038607495 scopus 로고    scopus 로고
    • Insulin resistance as a proinflammatory state: Mechanisms, mediators, and therapeutic interventions
    • Garg R, Tripathy D, Dandona P,. Insulin resistance as a proinflammatory state: mechanisms, mediators, and therapeutic interventions. Curr Drug Targets 2003; 4: 487-92.
    • (2003) Curr Drug Targets , vol.4 , pp. 487-492
    • Garg, R.1    Tripathy, D.2    Dandona, P.3
  • 44
    • 20044374023 scopus 로고    scopus 로고
    • Design and validation of a histological scoring system for nonalcoholic fatty liver disease
    • Kleiner DE, Brunt EM, Van Natta M, et al. Design and validation of a histological scoring system for nonalcoholic fatty liver disease. Hepatology 2005; 41: 1313-21.
    • (2005) Hepatology , vol.41 , pp. 1313-1321
    • Kleiner, D.E.1    Brunt, E.M.2    Van Natta, M.3


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