Differential regulation of proteoglycan-4 expression by IL-1α and TGF-β1 in rat condylar chondrocytes

Tohoku Journal of Experimental Medicine

Volumn 222, Issue 3, 2010, Pages 211-218

  Cheng, Jie ^a   Wang, Yanling ^a   Wang, Zilu ^a   Yang, Mifang ^a   Wu, Yunong ^a  

^a NANJING MEDICAL UNIVERSITY   (China)

Author keywords

Chondrocytes; IL 1 ; Mandibular condyle; Osteoarthritis; Proteoglycan 4; TGF 1

Indexed keywords

MESSENGER RNA; PROTEOGLYCAN; PROTEOGLYCAN 4; RECOMBINANT INTERLEUKIN 1ALPHA; RECOMBINANT TRANSFORMING GROWTH FACTOR BETA1; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CARTILAGE CELL; CELL CULTURE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG ANTAGONISM; DRUG EFFECT; DRUG MECHANISM; ENZYME LINKED IMMUNOSORBENT ASSAY; JOINT DESTRUCTION; MALE; MANDIBLE CONDYLE; NONHUMAN; OSTEOARTHRITIS; PROTEIN EXPRESSION; PROTEIN SYNTHESIS REGULATION; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TEMPOROMANDIBULAR JOINT; TIME; UPREGULATION;

ANALYSIS OF VARIANCE; ANIMALS; CHONDROCYTES; DNA PRIMERS; ENZYME-LINKED IMMUNOSORBENT ASSAY; GENE EXPRESSION REGULATION; HUMANS; INTERLEUKIN-1ALPHA; MALE; MANDIBULAR CONDYLE; PROTEOGLYCANS; RATS; RATS, SPRAGUE-DAWLEY; RECOMBINANT PROTEINS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; TRANSFORMING GROWTH FACTOR BETA1;

EID: 78249253599     PISSN: 00408727     EISSN: 13493329     Source Type: Journal    
DOI: 10.1620/tjem.222.211     Document Type: Article

References (30)

1. Chawla, K., Ham, H.O., Nguyen, T. & Messersmith, P.B. (2010) Molecular resurfacing of cartilage with proteoglycan 4. Acta Biomater., 6, 3388-3394.
2. DuRaine, G., Neu, C.P., Chan, S.M., Komvopoulos, K., June, R.K. & Reddi, A.H. (2009) Regulation of the friction coeficient of articular cartilage by TGF-beta1 and IL-1beta. J. Orthop. Res., 27, 249-256.
3. Elsaid, K.A., Jay, G.D. & Chichester, C.O. (2007) Reduced expression and proteolytic susceptibility of lubricin/supericial zone protein may explain early elevation in the coeficient of friction in the joints of rats with antigen-induced arthritis. Arthritis Rheum., 56, 108-116.
4. Flannery, C.R., Zollner, R., Corcoran, C., Jones, A.R., Root, A., Rivera-Bermúdez, M.A., Blanchet, T., Gleghorn, J.P., Bonassar, L.J., Bendele, A.M., Morris, E.A. & Glasson, S.S. (2009) Prevention of cartilage degeneration in a rat model of osteoarthritis by intraarticular treatment with recombinant lubricin. Arthritis Rheum., 60, 840-847.
5. Goldring, S.R. & Goldring, M.B. (2004) The role of cytokines in cartilage matrix degeneration in osteoarthritis. Clin. Orthop. Relat. Res., 427, 27-36.
6. Jay, G.D. (1992) Characterization of a bovine synovial luid lubricating factor. I. Chemical, surface activity and lubricating properties. Connect. Tissue Res., 28, 71-88.
7. Jones, A.R. & Flannery, C.R. (2007) Bioregulation of lubricin expression by growth factors and cytokines. Eur. Cell Mater., 13, 40-45.
8. Kamiya, T., Tanimoto, K., Tanne, Y., Lin, Y.Y., Kunimatsu, R., Yoshioka, M., Tanaka, N., Tanaka, E. & Tanne, K. (2010) Effects of mechanical stimuli on the synthesis of superficial zone protein in chondrocytes. J. Biomed. Mater. Res. A, 92, 801-805.
9. Kuroda, S., Tanimoto, K., Izawa, T., Fujihara, S., Koolstra, J.H. & Tanaka, E. (2009) Biomechanical and biochemical characteristics of the mandibular condylar cartilage. Osteoarthritis Cartilage, 17, 1408-1415.
10. Lai, Y.C., Shaftel, S.S., Miller, J.N., Tallents, R.H., Chang, Y., Pinkert, C.A., Olschowka, J.A., Dickerson, I.M., Puzas, J.E., O'Banion, M.K. & Kyrkanides, S. (2006) Intraarticular induction of interleukin-1beta expression in the adult mouse, with resultant temporomandibular joint pathologic changes, dysfunction, and pain. Arthritis Rheum., 54, 1184-1197.
11. Man, C., Zhu, S., Zhang, B. & Hu, J. (2009) Protection of articular cartilage from degeneration by injection of transforming growth factor-beta in temporomandibular joint osteoarthritis. Oral Surg. Oral Med. Oral Pathol. Oral Radiol. Endod., 108, 335-340.
12. Marcelino, J., Carpten, J.D., Suwairi, W.M., Gutierrez, O.M., Schwartz, S., Robbins, C., Sood, R., Makalowska, I., Baxevanis, A., Johnstone, B., Laxer, R.M., Zemel, L., Kim, C.A., Herd, J.K., Ihle, J., Williams, C., Johnson, M., Raman, V., Alonso, L.G., Brunoni, D., Gerstein, A., Papadopoulos, N., Bahabri, S.A., Trent, J.M. & Warman, M.L. (1999) CACP, encoding a secreted proteoglycan, is mutated in camptodactyly-arthropathy-coxa vara-pericarditis syndrome. Nat. Genet., 23, 319-322.
13. Martel-Pelletier, J., Alaaeddine, N. & Pelletier, J.P. (1999) Cytokines and their role in the pathophysiology of osteoarthritis. Front. Biosci., 4, 694-703.
14. Neu, C.P., Khalai, A., Komvopoulos, K., Schmid, T.M. & Reddi, A.H. (2007) Mechanotransduction of bovine articular carti-lage superficial zone protein by transforming growth factor beta signaling. Arthritis Rheum., 56, 3706-3714.
15. Niikura, T. & Reddi, A.H. (2007) Differential regulation of lubricin/superficial zone protein by transforming growth factor beta/bone morphogenetic protein superfamily members in articular chondrocytes and synoviocytes. Arthritis Rheum., 56, 2312-2321.
16. Nitzan, D.W. (2003) 'Friction and adhesive forces'-possible underlying causes for temporomandibular joint internal de-rangement. Cells Tissues Organs, 174, 6-16.
17. Ohno, S., Schmid, T., Tanne, Y., Kamiya, T., Honda, K., OhnoNakahara, M., Swentko, N., Desai, T.A., Tanne, K., Knudson, C.B. & Knudson, W. (2006) Expression of superficial zone protein in mandibular condyle cartilage. Osteoarthritis Cartilage, 14, 807-813.
18. Rhee, D.K., Marcelino, J., Baker, M., Gong, Y., Smits, P., Lefebvre, V., Jay, G.D., Stewart, M., Wang, H., Warman, M.L. & Carpten, J.D. (2005) The secreted glycoprotein lubricin protects cartilage surfaces and inhibits synovial cell overgrowth. J. Clin. Invest., 115, 622-631.
19. Scharstuhl, A., van Beuningen, H.M., Vitters, E.L., van der Kraan, P.M. & van den Berg, W.B. (2002) Loss of transforming growth factor counteraction on interleukin 1 mediated effects in cartilage of old mice. Ann. Rheum. Dis., 61, 1095-1098.
20. Schmidt, T.A., Gastelum, N.S., Han, E.H., Nugent-Derfus, G.E., Schumacher, B.L. & Sah, R.L. (2008) Differential regulation of proteoglycan 4 metabolism in cartilage by IL-1alpha, IGF-I, and TGF-beta1. Osteoarthritis Cartilage, 16, 90-97.
21. Schmidt, T.A., Gastelum, N.S., Nguyen, Q.T., Schumacher, B.L. & Sah, R.L. (2007) Boundary lubrication of articular cartilage: role of synovial luid constituents. Arthritis Rheum., 56, 882-891.
22. Swann, D.A. & Radin, E.L. (1972) The molecular basis of articular lubrication. I. Purification and properties of a lubricating fraction from bovine synovial luid. J. Biol. Chem., 247, 8069-8073.
23. Takahashi, N., Rieneck, K., van der Kraan, P.M., van Beuningen, H.M., Vitters, E.L., Bendtzen, K. & van den Berg, W.B. (2005) Elucidation of IL-1/TGF-beta interactions in mouse chondrocyte cell line by genome-wide gene expression. Osteoarthritis Cartilage, 13, 426-438.
24. Tanaka, E., Detamore, M.S. & Mercuri, L.G. (2008a) Degenerative disorders of the temporomandibular joint: etiology, diagnosis, and treatment. J. Dent. Res., 87, 296-307.
25. Tanaka, E., Detamore, M.S., Tanimoto, K. & Kawai, N. (2008b) Lubrication of the temporomandibular joint. Ann. Biomed. Eng., 36, 14-29.
26. Tanaka, E., Iwabe, T., Dalla-Bona, D.A., Kawai, N., van Eijden, T., Tanaka, M., Kitagawa, S., Takata, T. & Tanne, K. (2005) The effect of experimental cartilage damage and impairment and restoration of synovial lubrication on friction in the temporomandibular joint. J. Orofac. Pain, 19, 331-336.
27. Tanaka, E., Yamano, E., Dalla-Bona, D.A., Watanabe, M., Inubushi, T., Shirakura, M., Sano, R., Takahashi, K., van Eijden, T. & Tanne, K. (2006) Dynamic compressive properties of the mandibular condylar cartilage. J. Dent. Res., 85, 571-575.
28. Thirion, S. & Berenbaum, F. (2004) Culture and phenotyping of chondrocytes in primary culture. Methods Mol. Med., 100, 1-14.
29. Wei, L., Xiong, H., Li, B., Cheng, Y. & Long, X. (2010) Boundarylubricating ability and lubricin in synovial fluid of patients with temporomandibular joint disorders. J. Oral Maxillofac. Surg., 68, 2478-2483.
30. Young, A.A., McLennan, S., Smith, M.M., Smith S.M., Cake, M.A., Read, R.A., Melrose, J., Sonnabend, D.H., Flannery, C.R. & Little, C.B. (2006) Proteoglycan 4 downregulation in a sheep meniscectomy model of early osteoarthritis. Arthritis Res. Ther., 8, R41.