Prediction of malignant middle cerebral artery infarction by magnetic resonance imaging within 6 hours of symptom onset: A prospective multicenter observational study

Annals of Neurology

Volumn 68, Issue 4, 2010, Pages 435-445

  Thomalla, Götz ^a   Hartmann, Frank ^a   Juettler, Eric ^b,c   Singer, Oliver C ^d   Lehnhardt, Fritz Georg ^e   Köhrmann, Martin ^f   Kersten, Jan F ^a   Krützelmann, Anna ^a   Humpich, Marek C ^d   Sobesky, Jan ^c   Gerloff, Christian ^a   Villringer, Arno ^c,g   Fiehler, Jens ^a   Neumann Haefelin, Tobias ^d   Schellinger, Peter D ^f   Röther, Joachim ^h  

^a UNIVERSITY MEDICAL CENTER HAMBURG EPPENDORF   (Germany)

^b UNIVERSITY OF HEIDELBERG   (Germany)

^c CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

^d GOETHE UNIVERSITY   (Germany)

^e UNIVERSITY HOSPITAL OF COLOGNE   (Germany)

^f UNIVERSITY HOSPITAL ERLANGEN   (Germany)

^g UNIVERSITY OF LEIPZIG   (Germany)

^h KLINIKUM MINDEN   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; AGED; ARTICLE; BLOOD CLOT LYSIS; BRAIN ISCHEMIA; CEREBRAL ARTERY DISEASE; CLINICAL FEATURE; CLINICAL TRIAL; COHORT ANALYSIS; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DIFFUSION WEIGHTED IMAGING; DISEASE SEVERITY; FEMALE; HOSPITAL ADMISSION; HUMAN; HYPOTHESIS; INTERNAL CAROTID ARTERY OCCLUSION; MAGNETIC RESONANCE ANGIOGRAPHY; MAJOR CLINICAL STUDY; MALE; MULTICENTER STUDY; NATIONAL INSTITUTES OF HEALTH STROKE SCALE; NUCLEAR MAGNETIC RESONANCE IMAGING; OBSERVATIONAL STUDY; PREDICTION; PRIORITY JOURNAL; PROSPECTIVE STUDY; SCINTIGRAPHY; SENSITIVITY AND SPECIFICITY; AREA UNDER THE CURVE; CAROTID ARTERY DISEASE; FIBRINOLYTIC THERAPY; HOSPITALIZATION; METHODOLOGY; MIDDLE AGED; OBSERVATION; PATHOPHYSIOLOGY; PREDICTION AND FORECASTING; REGRESSION ANALYSIS; RETROSPECTIVE STUDY;

AGED; AREA UNDER CURVE; CAROTID ARTERY DISEASES; DIFFUSION MAGNETIC RESONANCE IMAGING; FEMALE; HUMANS; INFARCTION, MIDDLE CEREBRAL ARTERY; MAGNETIC RESONANCE ANGIOGRAPHY; MALE; MIDDLE AGED; OBSERVATION; PERFUSION IMAGING; PREDICTIVE VALUE OF TESTS; PROSPECTIVE STUDIES; REGRESSION ANALYSIS; RETROSPECTIVE STUDIES; SENSITIVITY AND SPECIFICITY; SEVERITY OF ILLNESS INDEX; THROMBOLYTIC THERAPY;

EID: 78149489835     PISSN: 03645134     EISSN: 15318249     Source Type: Journal    
DOI: 10.1002/ana.22125     Document Type: Article

References (37)

1. Heinsius T, Bogousslavsky J, Van Melle G., Large infarcts in the middle cerebral artery territory. Etiology and outcome patterns. Neurology 1998; 50: 341 350.
2. Ng LK, Nimmannitya J., Massive cerebral infarction with severe brain swelling: a clinicopathological study. Stroke 1970; 1: 158 163.
3. Pullicino PM, Alexandrov AV, Shelton JA, et al. Mass effect and death from severe acute stroke. Neurology 1997; 49: 1090 1095.
4. Silver FL, Norris JW, Lewis AJ, Hachinski VC., Early mortality following stroke: a prospective review. Stroke 1984; 15: 492 496.
5. Hacke W, Schwab S, Horn M, et al. 'Malignant' middle cerebral artery territory infarction: clinical course and prognostic signs. Arch Neurol 1996; 53: 309 315.
6. Ropper AH, Shafran B., Brain edema after stroke. Clinical syndrome and intracranial pressure. Arch Neurol 1984; 41: 26 29.
7. Berrouschot J, Sterker M, Bettin S, et al. Mortality of space-occupying ('malignant') middle cerebral artery infarction under conservative intensive care. Intensive Care Med 1998; 24: 620 623.
8. Vahedi K, Hofmeijer J, Juettler E, et al. Early decompressive surgery in malignant infarction of the middle cerebral artery: a pooled analysis of three randomised controlled trials. Lancet Neurol 2007; 6: 215 222.
9. Hofmeijer J, Kappelle LJ, Algra A, et al. Surgical decompression for space-occupying cerebral infarction (the Hemicraniectomy After Middle Cerebral Artery infarction with Life-threatening Edema Trial [HAMLET]): a multicentre, open, randomised trial. Lancet Neurol 2009; 8: 326 333.
10. Schwab S, Steiner T, Aschoff A, et al. Early hemicraniectomy in patients with complete middle cerebral artery infarction. Stroke 1998; 29: 1888 1893.
11. Cho DY, Chen TC, Lee HC., Ultra-early decompressive craniectomy for malignant middle cerebral artery infarction. Surg Neurol 2003; 60: 227 232.
12. Mori K, Nakao Y, Yamamoto T, Maeda M., Early external decompressive craniectomy with duroplasty improves functional recovery in patients with massive hemispheric embolic infarction: timing and indication of decompressive surgery for malignant cerebral infarction. Surg Neurol 2004; 62: 420 429.
13. Krieger DW, Demchuk AM, Kasner SE, et al. Early clinical and radiological predictors of fatal brain swelling in ischemic stroke. Stroke 1999; 30: 287 292.
14. Oppenheim C, Samson Y, Manai R, et al. Prediction of malignant middle cerebral artery infarction by diffusion-weighted imaging. Stroke 2000; 31: 2175 2181.
15. Kasner SE, Demchuk AM, Berrouschot J, et al. Predictors of fatal brain edema in massive hemispheric ischemic stroke. Stroke 2001; 32: 2117 2123.
16. Haring HP, Dilitz E, Pallua A, etal. Attenuated corticomedullary contrast: An early cerebral computed tomography sign indicating malignant middle cerebral artery infarction. A case-control study. Stroke 1999; 30: 1076 1082.
17. Kucinski T, Koch C, Grzyska U, et al. The predictive value of early CT and angiography for fatal hemispheric swelling in acute stroke. AJNR Am J Neuroradiol 1998; 19: 839 846.
18. von Kummer R, Meyding-Lamade U, Forsting M, et al. Sensitivity and prognostic value of early CT in occlusion of the middle cerebral artery trunk. AJNR Am J Neuroradiol 1994; 15: 9 15.
19. Hofmeijer J, Algra A, Kappelle LJ, van der, Worp HB., Predictors of life-threatening brain edema in middle cerebral artery infarction. Cerebrovasc Dis 2008; 25: 176 184.
20. Chalela JA, Kidwell CS, Nentwich LM, et al. Magnetic resonance imaging and computed tomography in emergency assessment of patients with suspected acute stroke: a prospective comparison. Lancet 2007; 369: 293 298.
21. Thomalla GJ, Kucinski T, Schoder V, et al. Prediction of malignant middle cerebral artery infarction by early perfusion- and diffusion-weighted magnetic resonance imaging. Stroke 2003; 34: 1892 1899.
22. Brott T, Adams HP Jr, Olinger CP, et al. Measurements of acute cerebral infarction: a clinical examination scale. Stroke 1989; 20: 864 870.
23. van Swieten JC, Koudstaal PJ, Visser MC, et al. Interobserver agreement for the assessment of handicap in stroke patients. Stroke 1988; 19: 604 607.
24. Adams HP Jr, Bendixen BH, Kappelle LJ, et al. Classification of subtype of acute ischemic stroke. Definitions for use in a multicenter clinical trial. TOAST. Trial of Org 10172 in Acute Stroke Treatment. Stroke 1993; 24: 35 41.
25. Fiebach JB, Schellinger PD, Gass A, et al. Stroke magnetic resonance imaging is accurate in hyperacute intracerebral hemorrhage: a multicenter study on the validity of stroke imaging. Stroke 2004; 35: 502 506.
26. Pencina MJ, D'Agostino RB Sr, D'Agostino RB Jr, Vasan RS., Evaluating the added predictive ability of a new marker: from area under the ROC curve to reclassification and beyond. Stat Med 2008; 27: 157 172. discussion 207-112.
27. Team RDC. R:, a language and environment for statistical computing. Vienna, Austria: R Foundation for Statistical Computing; 2009.
28. von Elm E, Altman DG, Egger M, et al. The Strengthening the Reporting of Observational Studies in Epidemiology (STROBE) statement: guidelines for reporting observational studies. Lancet 2007; 370: 1453 1457.
29. Neumann-Haefelin T, Sitzer M, du, Mesnil de Rochemont R, Lanfermann H., Prediction of malignant MCA infarction with DWI: pitfalls in hyperacute stroke. Stroke 2001; 32: 580 583.
30. Fiehler J, Knab R, Reichenbach JR, et al. Apparent diffusion coefficient decreases and magnetic resonance imaging perfusion parameters are associated in ischemic tissue of acute stroke patients. J Cereb Blood Flow Metab 2001; 21: 577 584.
31. Neumann-Haefelin T, Wittsack HJ, Wenserski F, et al. Diffusion- and perfusion-weighted MRI. The DWI/PWI mismatch region in acute stroke. Stroke 1999; 30: 1591 1597.
32. Schellinger PD, Fiebach JB, Jansen O, et al. Stroke magnetic resonance imaging within 6 hours after onset of hyperacute cerebral ischemia. Ann Neurol 2001; 49: 460 469.
33. Sobesky J, Zaro Weber O, Lehnhardt FG, et al. Which time-to-peak threshold best identifies penumbral flow? A comparison of perfusion-weighted magnetic resonance imaging and positron emission tomography in acute ischemic stroke. Stroke 2004; 35: 2843 2847.
34. Kakuda W, Lansberg MG, Thijs VN, et al. Optimal definition for PWI/DWI mismatch in acute ischemic stroke patients. J Cereb Blood Flow Metab 2008; 28: 887 891.
35. Olivot JM, Mlynash M, Thijs VN, et al. Optimal Tmax threshold for predicting penumbral tissue in acute stroke. Stroke 2009; 40: 469 475.
36. Linfante I, Llinas RH, Selim M, et al. Clinical and vascular outcome in internal carotid artery versus middle cerebral artery occlusions after intravenous tissue plasminogen activator. Stroke 2002; 33: 2066 2071.
37. Rubiera M, Ribo M, Delgado-Mederos R, et al. Tandem internal carotid artery/middle cerebral artery occlusion: an independent predictor of poor outcome after systemic thrombolysis. Stroke 2006; 37: 2301 2305.