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• Tubach F, Salmon D, Ravaud P, et al.: Risk of tuberculosis is higher with anti-tumor necrosis factor monoclonal antibody therapy than with soluble tumor necrosis factor receptor therapy: the three-year prospective French Research Axed on Tolerance of Biotherapies Registry. Arthritis Rheum 2009, 60:1884-1894. This observational study and that by Dixon et al. [37] suggest a higher risk of tuberculosis with use of monoclonal antibody anti-TNF agents than with the receptor antagonist etanercept.
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• Harrison MJ, Dixon WG, Watson KD, et al.: Rates of new-onset psoriasis in patients with rheumatoid arthritis receiving antitumour necrosis factor alpha therapy: results from the British Society for Rheumatology Biologics Register. Ann Rheum Dis 2009, 68:209-215. This was a large observational study on the incidence of psoriasis in RA patients treated with anti-TNF agents. The results suggest that the incidence of new-onset psoriasis is higher with use of adalimumab than with etanercept or infliximab.
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• Hetland ML, Christensen IJ, Tarp U, et al.: Direct comparison of treatment responses, remission rates, and drug adherence in patients with rheumatoid arthritis treated with adalimumab, etanercept, or infliximab: results from eight years of surveillance of clinical practice in the nationwide Danish DANBIO Registry. Arthritis Rheum 2010, 62:22-32. This was a population-based cohort study about the clinical effectiveness of anti-TNF agents in treatment of RA. The authors found that infliximab had the lowest rates of treatment response, disease remission, and drug adherence of the three agents; adalimumab had the highest rates of treatment response, and etanercept had the longest drug survival rates.
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