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Volumn 6, Issue 24, 2010, Pages 309-314

Use of in vitro assays to assess the potential antiproliferative and cytotoxic effects of saffron (Crocus sativus L.) in human lung cancer cell line

Author keywords

Cytotoxicity; L929; lung cancer; MTT; saffron

Indexed keywords

ALCOHOL; CROCUS SATIVUS EXTRACT; TETRAZOLIUM;

EID: 78149457185     PISSN: 09731296     EISSN: None     Source Type: Journal    
DOI: 10.4103/0973-1296.71799     Document Type: Article
Times cited : (107)

References (31)
  • 1
    • 77950507423 scopus 로고    scopus 로고
    • Body composition in patients with non-small cell lung cancer: A contemporary view of cancer cachexia with the use of computed tomography image analysis
    • Baracos VE, Reiman T, Mourtzakis M, Gioulbasanis I, Antoun S. Body composition in patients with non-small cell lung cancer: A contemporary view of cancer cachexia with the use of computed tomography image analysis. Am J Clin Nutr 2010;4:1133-7.
    • (2010) Am J Clin Nutr , vol.4 , pp. 1133-1137
    • Baracos, V.E.1    Reiman, T.2    Mourtzakis, M.3    Gioulbasanis, I.4    Antoun, S.5
  • 2
    • 77951879707 scopus 로고    scopus 로고
    • Maintenance therapy in advanced nonsmall cell lung cancer
    • Coate LE, Shepherd FA. Maintenance therapy in advanced nonsmall cell lung cancer. J Thorac Oncol 2010;5:723-34.
    • (2010) J Thorac Oncol , vol.5 , pp. 723-34
    • Coate, L.E.1    Shepherd, F.A.2
  • 3
    • 0034695162 scopus 로고    scopus 로고
    • Inhibition of epstein-barr virus early antigen activation promoted by 12-O tetradecanoylphorbol-13-acetate by the non-steroidal anti-inflammatory drugs
    • Kapadia GJ, Azuine MA, Takayasu J, Konoshima T, Takasaki M, Nishino H, et al. Inhibition of epstein-barr virus early antigen activation promoted by 12-O tetradecanoylphorbol-13-acetate by the non-steroidal anti-inflammatory drugs. Cancer Lett 2000;161:221-9.
    • (2000) Cancer Lett , vol.161 , pp. 221-229
    • Kapadia, G.J.1    Azuine, M.A.2    Takayasu, J.3    Konoshima, T.4    Takasaki, M.5    Nishino, H.6
  • 4
    • 0032704372 scopus 로고    scopus 로고
    • Perspectives on cancer chemoprevention research and drug development
    • Kelloff GJ. Perspectives on cancer chemoprevention research and drug development. Adv Cancer Res 2000;78:199-334.
    • (2000) Adv Cancer Res , vol.78 , pp. 199-334
    • Kelloff, G.J.1
  • 5
    • 0027184894 scopus 로고
    • Biological effects of saffron
    • Abdullaev FI. Biological effects of saffron. Biofactors 1993;4:83-6.
    • (1993) Biofactors , vol.4 , pp. 83-86
    • Abdullaev, F.I.1
  • 6
    • 0036377909 scopus 로고    scopus 로고
    • Cancer chemopreventive and tumoricidal properties of saffron (crocus sativus L.)
    • Abdullaev FI. Cancer chemopreventive and tumoricidal properties of saffron (Crocus sativus L.). Exp Biol Med 2002;227:20-5.
    • (2002) Exp Biol Med , vol.227 , pp. 20-25
    • Abdullaev, F.I.1
  • 7
    • 9644268896 scopus 로고    scopus 로고
    • Biomedical properties of saffron and its potential use in cancer therapy and chemoprevention trials
    • Abdullaev FI, Espinosa J, Aguirre J. Biomedical properties of saffron and its potential use in cancer therapy and chemoprevention trials. Cancer Detect Prev 2004;28:426-32.
    • (2004) Cancer Detect Prev , vol.28 , pp. 426-432
    • Abdullaev, F.I.1    Espinosa, J.2    Aguirre, J.3
  • 8
    • 77951140139 scopus 로고    scopus 로고
    • The effect of saffron consumption on biochemical and histopathological heart indices of rats with myocardial infarction
    • Joukar S, Najafipour H, Khaksari M, Sepehri G, Shahrokhi N, Dabiri S, et al. The effect of saffron consumption on biochemical and histopathological heart indices of rats with myocardial infarction. Cardiovasc Toxicol 2010;10:66-71.
    • (2010) Cardiovasc Toxicol , vol.10 , pp. 66-71
    • Joukar, S.1    Najafipour, H.2    Khaksari, M.3    Sepehri, G.4    Shahrokhi, N.5    Dabiri, S.6
  • 9
    • 33748188583 scopus 로고    scopus 로고
    • Evaluation of the antitussive effect of stigma and petals of saffron (Crocus sativus) and its components, safranal and crocin in guinea pigs
    • Hosseinzadeh H, Ghenaati J. Evaluation of the antitussive effect of stigma and petals of saffron (Crocus sativus) and its components, safranal and crocin in guinea pigs. Fitoterapia 2006;77:446-8.
    • (2006) Fitoterapia , vol.77 , pp. 446-448
    • Hosseinzadeh, H.1    Ghenaati, J.2
  • 10
    • 34548445132 scopus 로고    scopus 로고
    • Saffron in phytotherapy: Pharmacology and clinical uses
    • Schmidt M, Betti G, Hensel A. Saffron in phytotherapy: Pharmacology and clinical uses. Wien Med Wochenschr 2007;157:315-9.
    • (2007) Wien Med Wochenschr , vol.157 , pp. 315-319
    • Schmidt, M.1    Betti, G.2    Hensel, A.3
  • 11
    • 54449093368 scopus 로고    scopus 로고
    • Study of cytotoxic and apoptogenic properties of saffron extract in human cancer cell lines
    • Tavakkol-Afshari J, Brook A, Mousavi SH. Study of cytotoxic and apoptogenic properties of saffron extract in human cancer cell lines. Food Chem Toxicol 2008;46:3443-7.
    • (2008) Food Chem Toxicol , vol.46 , pp. 3443-3447
    • Tavakkol-Afshari, J.1    Brook, A.2    Mousavi, S.H.3
  • 12
    • 0021061819 scopus 로고
    • Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays
    • Mosmann T. Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays. J Immunol Methods 1983;65:55-9.
    • (1983) J Immunol Methods , vol.65 , pp. 55-59
    • Mosmann, T.1
  • 15
    • 0034105343 scopus 로고    scopus 로고
    • The cytotoxic effect of glucoconjugate extracted from corms of saffron plant (Crocus sativus) on human cell lines in culture
    • Escribano J, Diaz-Guerra MJ, Riese HH, Alvarez A, Proenza R, Fernández JA. The cytotoxic effect of glucoconjugate extracted from corms of saffron plant (Crocus sativus) on human cell lines in culture. Planta Med 2002;66:157-62.
    • (2002) Planta Med , vol.66 , pp. 157-162
    • Escribano, J.1    Diaz-Guerra, M.J.2    Riese, H.H.3    Alvarez, A.4    Proenza, R.5    Fernández, J.A.6
  • 16
    • 0028892819 scopus 로고
    • Crocetin protects against oxidative damage in rat primary hepatocytes
    • Tseng TH, Chu CY, Huang JM, Shiow SJ, Wang CJ. Crocetin protects against oxidative damage in rat primary hepatocytes. Cancer Lett 1995;97:61-7.
    • (1995) Cancer Lett , vol.97 , pp. 61-67
    • Tseng, T.H.1    Chu, C.Y.2    Huang, J.M.3    Shiow, S.J.4    Wang, C.J.5
  • 17
    • 2942615338 scopus 로고    scopus 로고
    • Crocetin from saffron: An active component of an ancient spice
    • Giaccio M. Crocetin from saffron: An active component of an ancient spice. Crit Rev Food Sci Nutr 2004;44:155-72.
    • (2004) Crit Rev Food Sci Nutr , vol.44 , pp. 155-172
    • Giaccio, M.1
  • 18
    • 0028177341 scopus 로고
    • Inhibitory effect of crocetin on intracellular nucleic acid and protein synthesis in malignant cells
    • Abdullaev FI. Inhibitory effect of crocetin on intracellular nucleic acid and protein synthesis in malignant cells. Toxicol Lett 1994;70:243-51.
    • (1994) Toxicol Lett , vol.70 , pp. 243-251
    • Abdullaev, F.I.1
  • 19
    • 0031474314 scopus 로고    scopus 로고
    • Carotenoids: Biology and treatment
    • Rock CL. Carotenoids: Biology and treatment. Pharmacol Ther 1997;75:185-97.
    • (1997) Pharmacol Ther , vol.75 , pp. 185-197
    • Rock, C.L.1
  • 20
    • 0034775553 scopus 로고    scopus 로고
    • Antioxidant and prooxidant properties of carotenoids
    • Young AJ, Lowe GM. Antioxidant and prooxidant properties of carotenoids. Arch Biochem Biophys 2001;385:20-7.
    • (2001) Arch Biochem Biophys , vol.385 , pp. 20-27
    • Young, A.J.1    Lowe, G.M.2
  • 21
    • 0032449901 scopus 로고    scopus 로고
    • Carotenoids and cancer: Prevention and potential therapy
    • Smith TA. Carotenoids and cancer: Prevention and potential therapy. Br J Biomed Sci 1998;55:268-75.
    • (1998) Br J Biomed Sci , vol.55 , pp. 268-275
    • Smith, T.A.1
  • 22
    • 0033802604 scopus 로고    scopus 로고
    • Colorful cancer prevention: Alpha-carotene, lycopene, and lung cancer
    • Heber D. Colorful cancer prevention: Alpha-carotene, lycopene, and lung cancer. Am J Clin Nutr 2000;72:901-7.
    • (2000) Am J Clin Nutr , vol.72 , pp. 901-907
    • Heber, D.1
  • 23
    • 2442604428 scopus 로고    scopus 로고
    • Crocin prevents the death of rat pheochromyctoma (PC-12) cells by its antioxidant effects stronger than those of a-tocopherol
    • Ochiaia T, Ohnoa S, Soedaa S, Tanakab H, Shoyamab Y, Shimenoa H. Crocin prevents the death of rat pheochromyctoma (PC-12) cells by its antioxidant effects stronger than those of a-tocopherol. Neurosci Lett 2004;362:61-4.
    • (2004) Neurosci Lett , vol.362 , pp. 61-64
    • Ochiaia, T.1    Ohnoa, S.2    Soedaa, S.3    Tanakab, H.4    Shoyamab, Y.5    Shimenoa, H.6
  • 24
    • 0026688491 scopus 로고
    • Beta-Carotene and alpha-tocopherol are synergistic antioxidants
    • Palozza P, Krinsky NI. Beta-Carotene and alpha-tocopherol are synergistic antioxidants. Arch Biochem Biophys 1992;297:184-7.
    • (1992) Arch Biochem Biophys , vol.297 , pp. 184-187
    • Palozza, P.1    Krinsky, N.I.2
  • 26
    • 0000536641 scopus 로고
    • Growth inhibition and induction of crythroid differentiation activity by crocin, dimethylcrocetine and b-carotene on K562 tumor cells
    • Morjani H, Tarantilis P, Polissiou M, Manfait M. Growth inhibition and induction of crythroid differentiation activity by crocin, dimethylcrocetine and b-carotene on K562 tumor cells. Anticancer Res 1990;10:1398-406.
    • (1990) Anticancer Res , vol.10 , pp. 1398-1406
    • Morjani, H.1    Tarantilis, P.2    Polissiou, M.3    Manfait, M.4
  • 27
    • 0030047682 scopus 로고    scopus 로고
    • Crocin, safranal and picrocrocin from saffron (Crocus sativus L.) inhibit the growth of human cancer cells in vitro
    • Escribano J, Alonso GL, Coca-Prados M, Fernández JA. Crocin, safranal and picrocrocin from saffron (Crocus sativus L.) inhibit the growth of human cancer cells in vitro. Cancer Lett 1996;100:23-30.
    • (1996) Cancer Lett , vol.100 , pp. 23-30
    • Escribano, J.1    Alonso, G.L.2    Coca-Prados, M.3    Fernández, J.A.4
  • 28
    • 0028834324 scopus 로고
    • Saffron chemoprevention in biology and medicine: A review
    • Nair SC, Kurumboor SK, Hasegawa JH. Saffron chemoprevention in biology and medicine: A review. Cancer Biother 1995;10: 257-64.
    • (1995) Cancer Biother , vol.10 , pp. 257-264
    • Nair, S.C.1    Kurumboor, S.K.2    Hasegawa, J.H.3
  • 29
    • 0028567256 scopus 로고
    • Inhibition of growth and induction of differentiation of promyelocytic leukemia (HL-60) by carotenoids from Crocus sativus L
    • Tarantilis PA, Morjani HM, Polissiou M, Manfait M. Inhibition of growth and induction of differentiation of promyelocytic leukemia (HL-60) by carotenoids from Crocus sativus L. Anticancer Res 1994;14:1913-8.
    • (1994) Anticancer Res , vol.14 , pp. 1913-1918
    • Tarantilis, P.A.1    Morjani, H.M.2    Polissiou, M.3    Manfait, M.4
  • 30
    • 77149166960 scopus 로고    scopus 로고
    • Roles of PKC isoforms in the induction of apoptosis elicited by aberrant Ras
    • Zhu T, Tsuji T, Chen C. Roles of PKC isoforms in the induction of apoptosis elicited by aberrant Ras. Oncogene 2010;29;1050-61.
    • (2010) Oncogene , vol.29 , pp. 1050-1061
    • Zhu, T.1    Tsuji, T.2    Chen, C.3
  • 31
    • 0343819945 scopus 로고    scopus 로고
    • Effects of long-term treatment of colon adenocarcinoma with crocin, a carotenoid from saffron (Crocus sativus L.): An experimental study in the rat
    • García-Olmo DC, Riese HH, Escribano J, Ontañón J, Fernández JA, Atienzar M, et al. Effects of long-term treatment of colon adenocarcinoma with crocin, a carotenoid from saffron (Crocus sativus L.): An experimental study in the rat. Nutr Cancer 1999;35:120-6.
    • (1999) Nutr Cancer , vol.35 , pp. 120-126
    • García-Olmo, D.C.1    Riese, H.H.2    Escribano, J.3    Ontañón, J.4    Fernández, J.A.5    Atienzar, M.6


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