Body composition in patients with non-small cell lung cancer: A contemporary view of cancer cachexia with the use of computed tomography image analysis

American Journal of Clinical Nutrition

Volumn 91, Issue 4, 2010, Pages

  Baracos, Vickie E ^a   Reiman, Tony ^b   Mourtzakis, Marina ^c   Gioulbasanis, Ioannis ^d   Antoun, Sami ^e  

^a UNIVERSITY OF ALBERTA   (Canada)

^b DALHOUSIE UNIVERSITY   (Canada)

^c UNIVERSITY OF WATERLOO   (Canada)

^d UNIVERSITY HOSPITAL OF LARISSA   (Greece)

^e INSTITUT GUSTAVE ROUSSY   (France)

Author keywords

[No Author keywords available]

Indexed keywords

2,4 THIAZOLIDINEDIONE DERIVATIVE; ACTIN; ADENOSINE TRIPHOSPHATE; ALKALI; ANGIOTENSIN II; CASPASE 3; HORMONE; INSULIN; INSULIN SENSITIZING AGENT; MUSCLE PROTEIN; NANDROLONE; PROTEASOME; SOMATOMEDIN; TESTOSTERONE; UBIQUITIN; ANTINEOPLASTIC AGENT;

ARTICLE; BONE METABOLISM; CATABOLISM; CHRONIC KIDNEY DISEASE; CLINICAL TRIAL; DIALYSIS; EXERCISE; FEEDING; HORMONAL THERAPY; HUMAN; INFORMATION; INSULIN RESISTANCE; METABOLIC ACIDOSIS; MORBIDITY; MORTALITY; MUSCLE ATROPHY; MUSCLE DISEASE; MUSCLE MASS; NONHUMAN; PROTEIN DEGRADATION; PROTEIN STRUCTURE; SIGNAL TRANSDUCTION; UREMIA; AGED; BODY COMPOSITION; BODY MASS; BODY WEIGHT; CACHEXIA; COMPUTER ASSISTED TOMOGRAPHY; FEMALE; LUNG NON SMALL CELL CANCER; LUNG TUMOR; MALE; METABOLISM; MIDDLE AGED; PROGNOSIS; PROSPECTIVE STUDY; RISK FACTOR; SEX DIFFERENCE; SKELETAL MUSCLE;

AGED; ANTINEOPLASTIC AGENTS; BODY COMPOSITION; BODY MASS INDEX; BODY WEIGHT; CACHEXIA; CARCINOMA, NON-SMALL-CELL LUNG; FEMALE; HUMANS; LUNG NEOPLASMS; MALE; MIDDLE AGED; MUSCLE, SKELETAL; MUSCULAR ATROPHY; PROGNOSIS; PROSPECTIVE STUDIES; RISK FACTORS; SEX FACTORS; TOMOGRAPHY, X-RAY COMPUTED;

EID: 77950507423     PISSN: 00029165     EISSN: None     Source Type: Journal    
DOI: 10.3945/ajcn.2010.28608C     Document Type: Article

References (36)

1. Lawson DH, Richmond A, Nixon DW, Rudman D. Metabolic approaches to cancer cachexia. Annu Rev Nutr 1982;2:277-301.
2. Dewys WD, Begg C, Lavin PT, et al. Prognostic effect of weight loss prior to chemotherapy in cancer patients. Eastern Cooperative Oncology Group. Am J Med 1980;69:491-497
3. Vigano A, Bruera E, Jhangri GS, Newman SC, Fields AL, Suarez-Almazor ME. Clinical survival predictors in patients with advanced cancer. Arch Intern Med 2000;160:861-868 (Pubitemid 30165248)
4. Palomares MR, Sayre JW, Shekar KC, Lillington LM, Chlebowski RT. Gender influence on weight-loss pattern and survival of nonsmall cell lung carcinoma patients. Cancer 1996;78:2119-2126
5. Jatoi A, Daly BD, Hughes VA, Dallal GE, Kehayias J, Roubenoff R. Do patients with nonmetastatic non-small cell lung cancer demonstrate altered resting energy expenditure? Ann Thorac Surg 2001;72:348-351
6. Mcmillan DC, Watson WS, Preston T, Mcardle CS. Lean body mass changes in cancer patients with weight loss. Clin Nutr 2000;19:403-406
7. Moley JF, Aamodt R, RumbleW, KayeW, Norton JA. Body cell mass in cancer-bearing and anorexic patients. J Parenter Enteral Nutr 1987;11: 219-222 (Pubitemid 17078035)
8. Pichard C, Kyle UG. Body composition measurements during wasting diseases. Curr Opin Clin Nutr Metab Care 1998;1:357-361 (Pubitemid 128539475)
9. Plank LD. Dual-energy X-ray absorptiometry and body composition. Curr Opin Clin Nutr Metab Care 2005;8:305-309 (Pubitemid 40586190)
10. Heymsfield SB, Wang Z, Baumgartner RN, Ross R. Human body composition: advances in models and methods. Annu Rev Nutr 1997;17: 527-558 (Pubitemid 27328812)
11. Mitsiopoulos N, Baumgartner RN, Heymsfield SB, Lyons W, Gallagher D, Ross R. Cadaver validation of skeletal muscle measurement by magnetic resonance imaging and computerized tomography. J Appl Physiol 1998;85:115-122 (Pubitemid 28334913)
12. Janssen I, Heymsfield SB, Wang ZM, Ross R. Skeletal muscle mass and distribution in 468 men and women aged 18-88 yr. J Appl Physiol 2000; 89:81-88 (Pubitemid 30482566)
13. Janssen I, Ross R. Effects of sex on the change in visceral, subcutaneous adipose tissue and skeletal muscle in response to weight loss. Int J Obes Relat Metab Disord 1999;23:1035-1046 (Pubitemid 29476206)
14. Shen W, Punyanitya M, Wang Z, et al. Total body skeletal muscle and adipose tissue volumes: estimation from a single abdominal cross-sectional image. J Appl Physiol 2004;97:2333-2338 (Pubitemid 39552474)
15. Miller KD, Jones E, Yanovski JA, Shankar R, Feuerstein I, Falloon J. Visceral abdominal-fat accumulation associated with use of indinavir. Lancet 1998;351:871-875 (Pubitemid 28121176)
16. Baumgartner RN, Koehler KM, Gallagher D, et al. Epidemiology of sarcopenia among the elderly in New Mexico. Am J Epidemiol 1998; 147:755-763 (Pubitemid 28183275)
17. Janssen I, Heymsfield SB, Ross R. Low relative skeletal muscle mass (sarcopenia) in older persons is associated with functional impairment and physical disability. J Am Geriatr Soc 2002;50:889-896 (Pubitemid 34496687)
18. Pichard C, Kyle UG, Morabia A, et al. Nutritional assessment: lean body mass depletion at hospital admission is associated with an increased length of stay. Am J Clin Nutr 2004;79:613-618 (Pubitemid 41103905)
19. Cosqueric G, Sebag A, Ducolombier C, et al. Sarcopenia is predictive of nosocomial infection in care of the elderly. Br J Nutr 2006;96:895-901. (Pubitemid 46454567)
20. Metter EJ, Talbot LA, Schrager M, Conwit R. Skeletal muscle strength as a predictor of all-cause mortality in healthy men. J Gerontol A Biol Sci Med Sci 2002;57:B359-65.
21. Baumgartner RN. Body composition in healthy aging. Ann N Y Acad Sci 2000;904:437-448
22. Zamboni M, Mazzali G, Fantin F, et al. Sarcopenic obesity: a new category of obesity in the elderly. Nutr Metab Cardiovasc Dis 2008;18: 388-395
23. Roubenoff R. Sarcopenic obesity: does muscle loss cause fat gain? Lessons from rheumatoid arthritis and osteoarthritis. Ann N YAcad Sci 2000;904:553-557 (Pubitemid 30389251)
24. Bouchard DR, Dionne IJ, Brochu M. Sarcopenic/Obesity and Physical Capacity in Older Men and Women: Data From the Nutrition as a Determinant of Successful Aging (NuAge)-the Quebec Longitudinal Study. Obesity (Silver Spring) 2009;17:2082-2088
25. Rolland Y, Lauwers-Cances V, Cristini C, et al. Difficulties with physical function associated with obesity, sarcopenia, and sarcopenic-obesity in community-dwelling elderly women: the EPIDOS (EPIDemiologie de l'OSteoporose) Study. Am J Clin Nutr 2009;89:1895-1900
26. Mourtzakis M, Prado CMM, Lieffers JR, et al. A practical and precise approach to quantification of body composition in cancer patients using computed tomography images acquired during routine care. Appl Physiol Nutr Metab 2008;33:997-1006.
27. Lieffers JR, Mourtzakis M, Hall KD, et al. A viscerally driven cachexia syndrome in patients with advanced colorectal cancer: contributions of organ and tumor mass to whole-body energy demands. Am J Clin Nutr 2009;89:1173-1179
28. Prado CM, Lieffers JR, McCargar LJ, et al. Prevalence and clinical implications of sarcopenic obesity in patients with solid tumours of the respiratory and gastrointestinal tracts: a population-based study. Lancet Oncol 2008;9:629-635
29. Prado CM, Baracos VE, McCargar LJ, et al. Body composition as an independent determinant of 5-fluorouracil-based chemotherapy toxicity. Clin Cancer Res 2007;13:3264-3268
30. Prado CM, Baracos VE, McCargar LJ, et al. Sarcopenia as a determinant of chemotherapy toxicity and time to tumor progression in metastatic breast cancer patients receiving capecitabine treatment. Clin Cancer Res 2009;15:2920-2926
31. Bauer J, Capra S, Ferguson M. Use of the scored Patient-Generated Subjective Global Assessment (PG-SGA) as a nutrition assessment tool in patients with cancer. Eur J Clin Nutr 2002;56:779-785
32. Perry GS, Byers TE, Mokdad AH, Serdula MK, Williamson DF. The validity of self-reports of past body weights by U.S. adults. Epidemiology 1995;6:61-66
33. Mosteller RD. Simplified calculation of body-surface area. N Engl J Med 1987;317:1098.
34. Evans WJ, Morley JE, Argiles J, et al. Cachexia: a new definition. Clin Nutr 2008;27:793-799
35. Shetty P. Malnutrition and undernutrition. Medicine 2003;31:18-22.
36. Simons JP, Schols AM, Buurman WA, Wouters EF. Weight loss and low body cell mass in males with lung cancer: relationship with systemic inflammation, acute-phase response, resting energy expenditure, and catabolic and anabolic hormones. Clin Sci (Lond) 1999;97:215-223