-
1
-
-
10744221383
-
Osteocyte control of bone formation via sclerostin, a novel BMP antagonist
-
Winkler D.G., Sutherland M.K., Geoghegan J.C., Yu C., Hayes T., Skonier J.E., Shpektor D., Jonas M., Kovacevich B.R., Staehling-Hampton K., Appleby M., Brunkow M.E., Latham J.A. Osteocyte control of bone formation via sclerostin, a novel BMP antagonist. EMBO J. 2003, 22:6267-6276.
-
(2003)
EMBO J.
, vol.22
, pp. 6267-6276
-
-
Winkler, D.G.1
Sutherland, M.K.2
Geoghegan, J.C.3
Yu, C.4
Hayes, T.5
Skonier, J.E.6
Shpektor, D.7
Jonas, M.8
Kovacevich, B.R.9
Staehling-Hampton, K.10
Appleby, M.11
Brunkow, M.E.12
Latham, J.A.13
-
3
-
-
18444400214
-
A 52-kb deletion in the SOST-MEOX1 intergenic region on 17q12-q21 is associated with van Buchem disease in the Dutch population
-
Staehling-Hampton K., Proll S., Paeper B.W., Zhao L., Charmley P., Brown A., Gardner J.C., Galas D., Schatzman R.C., Beighton P., Papapoulos S., Hamersma H., Brunkow M.E. A 52-kb deletion in the SOST-MEOX1 intergenic region on 17q12-q21 is associated with van Buchem disease in the Dutch population. Am. J. Med. Genet. 2002, 110:144-152.
-
(2002)
Am. J. Med. Genet.
, vol.110
, pp. 144-152
-
-
Staehling-Hampton, K.1
Proll, S.2
Paeper, B.W.3
Zhao, L.4
Charmley, P.5
Brown, A.6
Gardner, J.C.7
Galas, D.8
Schatzman, R.C.9
Beighton, P.10
Papapoulos, S.11
Hamersma, H.12
Brunkow, M.E.13
-
4
-
-
0035089781
-
Bone dysplasia sclerosteosis results from loss of the SOST gene product, a novel cystine knot-containing protein
-
Brunkow M.E., Gardner J.C., Van Ness J., Paeper B.W., Kovacevich B.R., Proll S., Skonier J.E., Zhao L., Sabo P.J., Fu Y., Alisch R.S., Gillett L., Colbert T., Tacconi P., Galas D., Hamersma H., Beighton P., Mulligan J. Bone dysplasia sclerosteosis results from loss of the SOST gene product, a novel cystine knot-containing protein. Am. J. Hum. Genet. 2001, 68:577-589.
-
(2001)
Am. J. Hum. Genet.
, vol.68
, pp. 577-589
-
-
Brunkow, M.E.1
Gardner, J.C.2
Van Ness, J.3
Paeper, B.W.4
Kovacevich, B.R.5
Proll, S.6
Skonier, J.E.7
Zhao, L.8
Sabo, P.J.9
Fu, Y.10
Alisch, R.S.11
Gillett, L.12
Colbert, T.13
Tacconi, P.14
Galas, D.15
Hamersma, H.16
Beighton, P.17
Mulligan, J.18
-
6
-
-
0017330858
-
Sclerosteosis - an autosomal recessive disorder
-
Beighton P., Davidson J., Durr L., Hamersma H. Sclerosteosis - an autosomal recessive disorder. Clin. Genet. 1977, 11:1-7.
-
(1977)
Clin. Genet.
, vol.11
, pp. 1-7
-
-
Beighton, P.1
Davidson, J.2
Durr, L.3
Hamersma, H.4
-
7
-
-
0017258367
-
The clinical features of sclerosteosis, a review of the manifestations in 25 affected individuals
-
Beighton P., Durr L., Hamersma H. The clinical features of sclerosteosis, a review of the manifestations in 25 affected individuals. Ann. Intern. Med. 1976, 84:393-397.
-
(1976)
Ann. Intern. Med.
, vol.84
, pp. 393-397
-
-
Beighton, P.1
Durr, L.2
Hamersma, H.3
-
8
-
-
0038267120
-
Sclerostin is a novel secreted osteoclast-derived bone morphogenetic protein antagonist with unique ligand specificity
-
Kusu N., Laurikkala J., Imanishi M., Usui H., Konishi M., Miyake A., Thesleff I., Itoh N. Sclerostin is a novel secreted osteoclast-derived bone morphogenetic protein antagonist with unique ligand specificity. J. Biol. Chem. 2003, 278:24113-24117.
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 24113-24117
-
-
Kusu, N.1
Laurikkala, J.2
Imanishi, M.3
Usui, H.4
Konishi, M.5
Miyake, A.6
Thesleff, I.7
Itoh, N.8
-
9
-
-
33846205505
-
Wnt signaling is involved in the inhibitory action of sclerostin on BMP-stimulated bone formation
-
Lowik C.W., van Bezooijen R.L. Wnt signaling is involved in the inhibitory action of sclerostin on BMP-stimulated bone formation. J. Musculoskelet. Neuronal Interact. 2006, 6:357.
-
(2006)
J. Musculoskelet. Neuronal Interact.
, vol.6
, pp. 357
-
-
Lowik, C.W.1
van Bezooijen, R.L.2
-
10
-
-
33845927993
-
Wnt but not BMP signaling is involved in the inhibitory action of sclerostin on BMP-stimulated bone formation
-
van Bezooijen R.L., Svensson J.P., Eefting D., Visser A., van der Horst G., Karperien M., Quax P.H., Vrieling H., Papapoulos S.E., ten Dijke P., Lowik C.W. Wnt but not BMP signaling is involved in the inhibitory action of sclerostin on BMP-stimulated bone formation. J. Bone Miner. Res. 2007, 22:19-28.
-
(2007)
J. Bone Miner. Res.
, vol.22
, pp. 19-28
-
-
van Bezooijen, R.L.1
Svensson, J.P.2
Eefting, D.3
Visser, A.4
van der Horst, G.5
Karperien, M.6
Quax, P.H.7
Vrieling, H.8
Papapoulos, S.E.9
ten Dijke, P.10
Lowik, C.W.11
-
11
-
-
33846449190
-
Bone density ligand, sclerostin, directly interacts with LRP5 but not LRP5G171V to modulate Wnt activity
-
Ellies D.L., Viviano B., McCarthy J., Rey J.P., Itasaki N., Saunders S., Krumlauf R. Bone density ligand, sclerostin, directly interacts with LRP5 but not LRP5G171V to modulate Wnt activity. J. Bone Miner. Res. 2006, 21:1738-1749.
-
(2006)
J. Bone Miner. Res.
, vol.21
, pp. 1738-1749
-
-
Ellies, D.L.1
Viviano, B.2
McCarthy, J.3
Rey, J.P.4
Itasaki, N.5
Saunders, S.6
Krumlauf, R.7
-
12
-
-
13244298422
-
Sclerostin inhibition of Wnt-3a-induced C3H10T1/2 cell differentiation is indirect and mediated by bone morphogenetic proteins
-
Winkler D.G., Sutherland M.S., Ojala E., Turcott E., Geoghegan J.C., Shpektor D., Skonier J.E., Yu C., Latham J.A. Sclerostin inhibition of Wnt-3a-induced C3H10T1/2 cell differentiation is indirect and mediated by bone morphogenetic proteins. J. Biol. Chem. 2005, 280:2498-2502.
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 2498-2502
-
-
Winkler, D.G.1
Sutherland, M.S.2
Ojala, E.3
Turcott, E.4
Geoghegan, J.C.5
Shpektor, D.6
Skonier, J.E.7
Yu, C.8
Latham, J.A.9
-
13
-
-
4344660363
-
Noggin and sclerostin bone morphogenetic protein antagonists form a mutually inhibitory complex
-
Winkler D.G., Yu C., Geoghegan J.C., Ojala E.W., Skonier J.E., Shpektor D., Sutherland M.K., Latham J.A. Noggin and sclerostin bone morphogenetic protein antagonists form a mutually inhibitory complex. J. Biol. Chem. 2004, 279:36293-36298.
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 36293-36298
-
-
Winkler, D.G.1
Yu, C.2
Geoghegan, J.C.3
Ojala, E.W.4
Skonier, J.E.5
Shpektor, D.6
Sutherland, M.K.7
Latham, J.A.8
-
14
-
-
12144286871
-
Sclerostin is an osteocyte-expressed negative regulator of bone formation, but not a classical BMP antagonist
-
van Bezooijen R.L., Roelen B.A., Visser A., van der Wee-Pals L., de Wilt E., Karperien M., Hamersma H., Papapoulos S.E., ten Dijke P., Lowik C.W. Sclerostin is an osteocyte-expressed negative regulator of bone formation, but not a classical BMP antagonist. J. Exp. Med. 2004, 199:805-814.
-
(2004)
J. Exp. Med.
, vol.199
, pp. 805-814
-
-
van Bezooijen, R.L.1
Roelen, B.A.2
Visser, A.3
van der Wee-Pals, L.4
de Wilt, E.5
Karperien, M.6
Hamersma, H.7
Papapoulos, S.E.8
ten Dijke, P.9
Lowik, C.W.10
-
15
-
-
74849118439
-
Sclerostin binds and regulates the activity of cysteine-rich protein 61
-
Craig T.A., Bhattacharya R., Mukhopadhyay D., Kumar R. Sclerostin binds and regulates the activity of cysteine-rich protein 61. Biochem. Biophys. Res. Commun. 2010, 392:36-40.
-
(2010)
Biochem. Biophys. Res. Commun.
, vol.392
, pp. 36-40
-
-
Craig, T.A.1
Bhattacharya, R.2
Mukhopadhyay, D.3
Kumar, R.4
-
16
-
-
0004270170
-
-
John Wiley and Sons
-
Ausubel F.M., Brent R., Kingston R.E., Moore D.D., Seidman J.G., Smith J.A., Struhl K. Current Protocols in Molecular Biology 2007, John Wiley and Sons.
-
(2007)
Current Protocols in Molecular Biology
-
-
Ausubel, F.M.1
Brent, R.2
Kingston, R.E.3
Moore, D.D.4
Seidman, J.G.5
Smith, J.A.6
Struhl, K.7
-
17
-
-
0036138175
-
A mutation in the LDL receptor-related protein 5 gene results in the autosomal dominant high-bone-mass trait
-
Little R.D., Carulli J.P., Del Mastro R.G., Dupuis J., Osborne M., Folz C., Manning S.P., Swain P.M., Zhao S.C., Eustace B., Lappe M.M., Spitzer L., Zweier S., Braunschweiger K., Benchekroun Y., Hu X., Adair R., Chee L., FitzGerald M.G., Tulig C., Caruso A., Tzellas N., Bawa A., Franklin B., McGuire S., Nogues X., Gong G., Allen K.M., Anisowicz A., Morales A.J., Lomedico P.T., Recker S.M., Van Eerdewegh P., Recker R.R., Johnson M.L. A mutation in the LDL receptor-related protein 5 gene results in the autosomal dominant high-bone-mass trait. Am. J. Hum. Genet. 2002, 70:11-19.
-
(2002)
Am. J. Hum. Genet.
, vol.70
, pp. 11-19
-
-
Little, R.D.1
Carulli, J.P.2
Del Mastro, R.G.3
Dupuis, J.4
Osborne, M.5
Folz, C.6
Manning, S.P.7
Swain, P.M.8
Zhao, S.C.9
Eustace, B.10
Lappe, M.M.11
Spitzer, L.12
Zweier, S.13
Braunschweiger, K.14
Benchekroun, Y.15
Hu, X.16
Adair, R.17
Chee, L.18
FitzGerald, M.G.19
Tulig, C.20
Caruso, A.21
Tzellas, N.22
Bawa, A.23
Franklin, B.24
McGuire, S.25
Nogues, X.26
Gong, G.27
Allen, K.M.28
Anisowicz, A.29
Morales, A.J.30
Lomedico, P.T.31
Recker, S.M.32
Van Eerdewegh, P.33
Recker, R.R.34
Johnson, M.L.35
more..
-
18
-
-
0037136577
-
High bone density due to a mutation in LDL-receptor-related protein 5
-
Little R.D., Recker R.R., Johnson M.L. High bone density due to a mutation in LDL-receptor-related protein 5. N. Engl. J. Med. 2002, 347:943-944.
-
(2002)
N. Engl. J. Med.
, vol.347
, pp. 943-944
-
-
Little, R.D.1
Recker, R.R.2
Johnson, M.L.3
-
19
-
-
0037118285
-
High bone density due to a mutation in LDL-receptor-related protein 5
-
Boyden L.M., Mao J., Belsky J., Mitzner L., Farhi A., Mitnick M.A., Wu D., Insogna K., Lifton R.P. High bone density due to a mutation in LDL-receptor-related protein 5. N. Engl. J. Med. 2002, 346:1513-1521.
-
(2002)
N. Engl. J. Med.
, vol.346
, pp. 1513-1521
-
-
Boyden, L.M.1
Mao, J.2
Belsky, J.3
Mitzner, L.4
Farhi, A.5
Mitnick, M.A.6
Wu, D.7
Insogna, K.8
Lifton, R.P.9
-
20
-
-
0023281610
-
Isolation of EGF-dependent transforming growth factor (TGF beta-like) activity from culture medium conditioned by fetal rat calvariae
-
Centrella M., Canalis E. Isolation of EGF-dependent transforming growth factor (TGF beta-like) activity from culture medium conditioned by fetal rat calvariae. J. Bone Miner. Res. 1987, 2:29-36.
-
(1987)
J. Bone Miner. Res.
, vol.2
, pp. 29-36
-
-
Centrella, M.1
Canalis, E.2
-
21
-
-
0024456086
-
Chondrogenesis of mandibular mesenchyme from the embryonic chick is inhibited by mandibular epithelium and by epidermal growth factor
-
Coffin-Collins P.A., Hall B.K. Chondrogenesis of mandibular mesenchyme from the embryonic chick is inhibited by mandibular epithelium and by epidermal growth factor. Int. J. Dev. Biol. 1989, 33:297-311.
-
(1989)
Int. J. Dev. Biol.
, vol.33
, pp. 297-311
-
-
Coffin-Collins, P.A.1
Hall, B.K.2
-
22
-
-
0032189305
-
Roles of transforming growth factor-alpha and epidermal growth factor in chick limb development
-
Dealy C.N., Scranton V., Cheng H.C. Roles of transforming growth factor-alpha and epidermal growth factor in chick limb development. Dev. Biol. 1998, 202:43-55.
-
(1998)
Dev. Biol.
, vol.202
, pp. 43-55
-
-
Dealy, C.N.1
Scranton, V.2
Cheng, H.C.3
-
23
-
-
0035029842
-
Formation of the sphenomandibular ligament by Meckel's cartilage in the mouse: possible involvement of epidermal growth factor as revealed by studies in vivo and in vitro
-
Ishizeki K., Takahashi N., Nawa T. Formation of the sphenomandibular ligament by Meckel's cartilage in the mouse: possible involvement of epidermal growth factor as revealed by studies in vivo and in vitro. Cell Tissue Res. 2001, 304:67-80.
-
(2001)
Cell Tissue Res.
, vol.304
, pp. 67-80
-
-
Ishizeki, K.1
Takahashi, N.2
Nawa, T.3
-
24
-
-
0032930859
-
Epidermal growth factor receptor function is necessary for normal craniofacial development and palate closure
-
Miettinen P.J., Chin J.R., Shum L., Slavkin H.C., Shuler C.F., Derynck R., Werb Z. Epidermal growth factor receptor function is necessary for normal craniofacial development and palate closure. Nat. Genet. 1999, 22:69-73.
-
(1999)
Nat. Genet.
, vol.22
, pp. 69-73
-
-
Miettinen, P.J.1
Chin, J.R.2
Shum, L.3
Slavkin, H.C.4
Shuler, C.F.5
Derynck, R.6
Werb, Z.7
-
25
-
-
0033374802
-
Convergence of the BMP and EGF signaling pathways on Smad1 in the regulation of chondrogenesis
-
Nonaka K., Shum L., Takahashi I., Takahashi K., Ikura T., Dashner R., Nuckolls G.H., Slavkin H.C. Convergence of the BMP and EGF signaling pathways on Smad1 in the regulation of chondrogenesis. Int. J. Dev. Biol. 1999, 43:795-807.
-
(1999)
Int. J. Dev. Biol.
, vol.43
, pp. 795-807
-
-
Nonaka, K.1
Shum, L.2
Takahashi, I.3
Takahashi, K.4
Ikura, T.5
Dashner, R.6
Nuckolls, G.H.7
Slavkin, H.C.8
-
26
-
-
0037279923
-
Transgenic and knock-out mice for deciphering the roles of EGFR ligands
-
Wong R.W. Transgenic and knock-out mice for deciphering the roles of EGFR ligands. Cell. Mol. Life Sci. 2003, 60:113-118.
-
(2003)
Cell. Mol. Life Sci.
, vol.60
, pp. 113-118
-
-
Wong, R.W.1
-
27
-
-
0034697018
-
Epidermal growth factor negatively regulates chondrogenesis of mesenchymal cells by modulating the protein kinase C-alpha, Erk-1, and p38 MAPK signaling pathways
-
Yoon Y.M., Oh C.D., Kim D.Y., Lee Y.S., Park J.W., Huh T.L., Kang S.S., Chun J.S. Epidermal growth factor negatively regulates chondrogenesis of mesenchymal cells by modulating the protein kinase C-alpha, Erk-1, and p38 MAPK signaling pathways. J. Biol. Chem. 2000, 275:12353-12359.
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 12353-12359
-
-
Yoon, Y.M.1
Oh, C.D.2
Kim, D.Y.3
Lee, Y.S.4
Park, J.W.5
Huh, T.L.6
Kang, S.S.7
Chun, J.S.8
-
28
-
-
0034623957
-
Expression of epidermal growth factor in transgenic mice causes growth retardation
-
Chan S.Y., Wong R.W. Expression of epidermal growth factor in transgenic mice causes growth retardation. J. Biol. Chem. 2000, 275:38693-38698.
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 38693-38698
-
-
Chan, S.Y.1
Wong, R.W.2
|