Targeted deletion of the tachykinin 4 gene (TAC4-/-) influences the early stages of B lymphocyte development

Blood

Volumn 116, Issue 19, 2010, Pages 3792-3801

  Berger, Alexandra ^a   Benveniste, Patricia ^b   Corfe, Steven A ^a   Tran, Anne H ^a   Barbara, Mary ^b   Wakeham, Andrew ^a   Mak, Tak W ^a   Iscove, Norman N ^b   Paige, Christopher J ^a,b  

^a PRINCESS MARGARET HOSPITAL   (Canada)

^b UNIVERSITY HEALTH NETWORK   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

CD19 ANTIGEN; STEM CELL FACTOR RECEPTOR; TACHYKININ; TACHYKININ 4; UNCLASSIFIED DRUG;

ARTICLE; B LYMPHOCYTE; BONE MARROW; CELL CULTURE; CELL DIFFERENTIATION; CELL MATURATION; CELL PROLIFERATION; GENE DELETION; GENE TARGETING; HEMATOPOIESIS; MOUSE; NONHUMAN; PRIORITY JOURNAL;

EID: 78149433577     PISSN: 00064971     EISSN: 15280020     Source Type: Journal    
DOI: 10.1182/blood-2010-06-291062     Document Type: Article

References (35)

1. Bellucci F, Carini F, Catalani C, et al. Pharmacological profile of the novel mammalian tachykinin, hemokinin 1. Br J Pharmacol. 2002;135(1):266-274. (Pubitemid 34102121)
2. Berger A, Paige CJ. Hemokinin-1 has substance P-like function in U-251 MG astrocytoma cells: a pharmacological and functional study. J Neuroimmunol. 2005;164(1):48-56. (Pubitemid 40826762)
3. Camarda V, Rizzi A, Calo G, Guerrini R, Salvadori S, Regoli D. Pharmacological profile of hemokinin 1: a novel member of the tachykinin family. Life Sci. 2002;71(4):363-370. (Pubitemid 34607301)
4. Duffy RA, Hedrick JA, Randolph G, et al. Centrally administered hemokinin-1 (HK-1), a neurokinin NK1 receptor agonist, produces substance P-like behavioral effects in mice and gerbils. Neuropharmacology. 2003;45(2):242-250. (Pubitemid 36782537)
5. Morteau O, Lu B, Gerard C, Gerard NP. Hemokinin 1 is a full agonist at the substance P receptor. Nat Immunol. 2001;2(12):1088. (Pubitemid 33130136)
6. Page NM, Bell NJ, Gardiner SM, et al. Characterization of the endokinins: human tachykinins with cardiovascular activity. Proc Natl Acad Sci U S A. 2003;100(10):6245-6250.
7. Kurtz MM, Wang R, Clements MK, et al. Identification, localization and receptor characterization of novel mammalian substance P-like peptides. Gene. 2002;296(1):205-212. (Pubitemid 35287339)
8. Page NM. Characterization of the gene structures, precursor processing and pharmacology of the endokinin peptides. Vascul Pharmacol. 2006;45(4):200-208.
9. Zhang Y, Lu L, Furlonger C,Wu GE, Paige CJ. Hemokinin is a hematopoietic-specific tachykinin that regulates B lymphopoiesis. Nat Immunol. 2000;1(5):392-397.
10. Wang W, Li Q, Zhang J, et al. Hemokinin-1 activates the MAPK pathway and enhances B cell proliferation and antibody production. J Immunol. 2010;184(7):3590-3597.
11. Zhang Y, Paige CJ. T-cell developmental blockage by tachykinin antagonists and the role of hemokinin 1 in T lymphopoiesis. Blood. 2003;102(6):2165-2172. (Pubitemid 37122394)
12. Janelsins BM, Mathers AR, Tkacheva OA, et al. Proinflammatory tachykinins that signal through the neurokinin 1 receptor promote survival of dendritic cells and potent cellular immunity. Blood. 2009;113(13):3017-3026.
13. Zhao YL, Tao Y, Fu CY, Kong ZQ, Chen Q, Wang R. Human hemokinin-1 and human hemokinin- 1(4-11), mammalian tachykinin peptides, suppress proliferation and induce differentiation in HL-60 cells. Peptides. 2009;30(8):1514-1522.
14. Benveniste P, Frelin C, Janmohamed S, et al. Intermediate-term hematopoietic stem cells with extended but time-limited reconstitution potential. Cell Stem Cell. 2010;6(1):48-58.
15. Iscove NN, Barbara M, Gu M, Gibson M, Modi C, Winegarden N. Representation is faithfully preserved in global cDNA amplified exponentially from sub-picogram quantities of mRNA. Nat Biotechnol. 2002;20(9):940-943. (Pubitemid 35001134)
16. Muro EM, Herrington R, Janmohamed S, Frelin C, Andrade-Navarro MA, Iscove NN. Identification of gene 3′ ends by automated EST cluster analysis. Proc Natl Acad Sci U S A. 2008;105(51):20286-20290.
17. Page NM. Hemokinins and endokinins. Cell Mol Life Sci. 2004;61(13):1652-1663.
18. Berger A, Tran AH, Paige CJ. Co-regulated decrease of Neurokinin-1 receptor and Hemokinin-1 gene expression in monocytes and macrophages after activation with pro-inflammatory cytokines. J Neuroimmunol. 2007;187(1):83-93. (Pubitemid 47008930)
19. Graham GJ, Stevens JM, Page NM, et al. Tachykinins regulate the function of platelets. Blood. 2004;104(4):1058-1065.
20. Jones S, Tucker KL, Sage T, et al. Peripheral tachykinins and the neurokinin receptor NK1 are required for platelet thrombus formation. Blood. 2008;111(2):605-612.
21. Klassert TE, Pinto F, Hernandez M, et al. Differential expression of neurokinin B and hemokinin-1 in human immune cells. J Neuroimmunol. 2008;196(1):27-34.
22. Nelson DA, Marriott I, Bost KL. Expression of hemokinin 1 mRNA by murine dendritic cells. J Neuroimmunol. 2004;155(1):94-102. (Pubitemid 39165781)
23. Nelson D, Bost K. Non-neuronal mammalian tachykinin expression. Front Biosci. 2004;9:2166-2176.
24. Metwali A, Blum AM, Elliott DE, Setiawan T, Weinstock JV. Cutting edge: hemokinin has substance P-like function and expression in inflammation. J Immunol. 2004;172(11):6528-6532. (Pubitemid 38669085)
25. Zhang Y, Berger A, Milne CD, Paige CJ. Tachykinins in the immune system. Curr Drug Targets. 2006;7(8):1011-1020.
26. Benveniste P, Cantin C, Hyam D, Iscove NN. Hematopoietic stem cells engraft in mice with absolute efficiency. Nat Immunol. 2003;4(7):708-713. (Pubitemid 36874449)
27. Rameshwar P, Gascon P. Induction of negative hematopoietic regulators by neurokinin-A in bone marrow stroma. Blood. 1996;88(1):98-106. (Pubitemid 26230676)
28. Rameshwar P, Poddar A, Zhu G, Gascon P. Receptor induction regulates the synergistic effects of substance P with IL-1 and platelet-derived growth factor on the proliferation of bone marrow fibroblasts. J Immunol. 1997;158(7):3417- 3424. (Pubitemid 127484062)
29. Gascon P, Qian J, Joshi DD, Teli T, Haider A, Rameshwar P. Effects of preprotachykinin-I peptides on hematopoietic homeostasis: a role for bone marrow endopeptidases. Ann N Y Acad Sci. 2000;917:416-423.
30. Patel N, Castillo M, Rameshwar P. An in vitro method to study the effects of hematopoietic regulators during immune and blood cell development. Biol Proced Online. 2007;9:56-64.
31. Chernova I, Lai JP, Li H, et al. Substance P (SP) enhances CCL5-induced chemotaxis and intracellular signaling in human monocytes, which express the truncated neurokinin-1 receptor (NK1R). J Leukoc Biol. 2009;85(1):154-164.
32. Lai JP, Ho WZ, Kilpatrick LE, et al. Full-length and truncated neurokinin-1 receptor expression and function during monocyte/macrophage differentiation. Proc Natl Acad Sci U S A. 2006;103(20):7771-7776. (Pubitemid 43752856)
33. Lai JP, Douglas SD, Wang YJ, Ho WZ. Real-time reverse transcription-PCR quantitation of substance P receptor (NK-1R) mRNA. Clin Diagn Lab Immunol. 2005;12(4):537-541.
34. Marriott I, Bost KL. Substance P receptor mediated macrophage responses. Adv Exp Med Biol. 2001;493:247-254. (Pubitemid 34020235)
35. Simeonidis S, Castagliuolo I, Pan A, et al. Regulation of the NK-1 receptor gene expression in human macrophage cells via an NF-kappa B site on its promoter. Proc Natl Acad Sci U S A. 2003;100(5):2957-2962. (Pubitemid 36297605)