Nosocomial outbreak of septicaemia in neonatal intensive care unit due to extended spectrum β-lactamase producing Klebsiella pneumoniae showing multiple mechanisms of drug resistance

Indian Journal of Medical Microbiology

Volumn 28, Issue 4, 2010, Pages 380-384

  Rastogi, V ^a   Nirwan, P S ^a   Jain, S ^a   Kapil, A ^b  

^a JLN MC and Asso Hospitals   (India)

^b ALL INDIA INSTITUTE OF MEDICAL SCIENCES   (India)

Author keywords

Extended spectrum lactamase; Klebsiella pneumoniae; neonatal septicaemia; outbreak

Indexed keywords

CEFOTAXIME; CEFTAZIDIME; EXTENDED SPECTRUM BETA LACTAMASE;

ANTIBIOTIC RESISTANCE; ARTICLE; BACTERIAL STRAIN; BACTERIUM ISOLATE; BLOOD; CONTROLLED STUDY; EPIDEMIC; HOSPITAL ADMISSION; HOSPITAL INFECTION; KLEBSIELLA PNEUMONIAE; NEWBORN INTENSIVE CARE; NONHUMAN; PHENOTYPE; POLYMERASE CHAIN REACTION; SCREENING; SEPTICEMIA;

EID: 78149430196     PISSN: 02550857     EISSN: 19983646     Source Type: Journal    
DOI: 10.4103/0255-0857.71834     Document Type: Article

References (15)

1. Kuruvilla KA, Pillai S, Jesudasan M, Jana AK. Bacterial Profile of sepsis in a neonatal unit in south India. Indian Pediatr 1998;35:851-8. (Pubitemid 28452552)
2. Ben-Hancouda T, Foulon T, Ben-Mahrez K. Involvement of SHV - 12 and SHV - 2a encloding plasmids in outbreaks of ESBL Producing K. pneumoniae in a Tunisian neonatal ward. Microb Drug Resist 2004;10:132-8.
3. th ed. CLSI document M2-A9. Wayne, PA: 2006.
4. Silva J, Gatica R, Aguilar C, Becerra Z, Garza-Ramos U, Velázquez M, et al. Outbreak of infection with ESBL producing, K. pneumoniae in a Mexican hospital. J Clin Microbiol 2001;39:3193-6.
5. Peña C, Pujol M, Ardanuy C, Ricart A, Pallares R, Liñares J, et al. Epidemiology and successful control of a large outbreak due to K. pneumoniae producing ESBL. Antimicrob Agents Chemother 1998;42:53-8.
6. Anatha Krishnan AN, Kanungo R, Kumar A, Badrinath S. Extended spectrum beta lactamase producers among surgical wound infections and burns patients in JIPMER. Indian J Med Microbiol 2000;18:160-5.
7. Podschun R, Ullmann U. Klebsiella species as nosocomial pathogens: Epidemiology, taxonomy, typing methods and pathogenicity factors. Clin Microbiol Rev 1998;11:589-603.
8. Banerjee M, Sahu K, Bhattacharya S, Adhya S, Bhowmick P, Chakraborty P. Outbreak of neonatal septicaemia with multidrug resistant K. pneumoniae. Indian J Pediatr 1993;60:25-7. (Pubitemid 23064660)
9. Siu LK, Lu PL, Hsuch PR, Lin FM, Chang SC, Luh KT, et al. Bacteremia due to extended spectrum beta. Lactamase producing Escherichia coli and Klebsiella pneumoniae in a pediatric oncology ward: Clinical features and identification of different plasmids carrying both SHV - 5 and TEM - 1 genes. J Clin Microbiol 1999;37:4020-7.
10. Shanmuganathan C, Ananthakrishnan A, Jayakeerthi SR, Kanungo R, Kumar A, Bhattacharya S, et al. Learning from an outbreak: ESBL - The essential points. Indian J Med Microbiol 2004;22:255-7. (Pubitemid 39409714)
11. Zhang R, Yang L, Cai JC, Zhou HW, Chen GX. High level carbapenem resistance in Citrobacter freundii clinical isolate is due to a combination of KPC-2 production and decreased porin expression. J Med Microbiol 2008;57:332-7. (Pubitemid 351358536)
12. National committee for clinical laboratory standards. Performace standards for antimicrobial disk susceptibility tests; Approved standard M2-A7. NCCLS, Wayne, PA; 2000.
13. Rodrigues C, Joshi P, Jani SH, Alphonse M, Radhakrishnan R, Mehta A. Detection of β-lactamases in nosocomial gram negative clinical isolates. Indian J Med Microbiol 2004;22:247-50. (Pubitemid 39409712)
14. Kumar MS, Lakshmi V, Rajagopalan R. Occurrence of extended spectrum β-lactamases among enterobacteriacae species isolated at a tertiary care institute. Indian J Med Microbiol 2006;24:208-11. (Pubitemid 44315655)
15. De Champs C, Sirot D, Chanal C, Bonnet R, Sirot J. A 1998 survey of ESBL in enterobacteriacae in France. Antimicrob Agents Chemother 1998;44:3177-9.