Phase i clinical trial of hepatic arterial infusion of cisplatin in combination with intravenous liposomal doxorubicin in patients with advanced cancer and dominant liver involvement

Cancer Chemotherapy and Pharmacology

Volumn 66, Issue 6, 2010, Pages 1087-1093

  Tsimberidou, Apostolia M ^a   Moulder, Stacy ^a   Fu, Siqing ^a   Wen, Sijin ^a   Naing, Aung ^a   Bedikian, Agop Y ^a   Daring, Shawn ^a   Uehara, Cynthia ^a   Ng, Chaan ^a   Wallace, Michael ^a   Camacho, Luis ^b   Kurzrock, Razelle ^a  

^a UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

^b Oncology Consultants   (United States)

Author keywords

Cisplatin; Doxil; Hepatic arterial infusion; Phase I trial

Indexed keywords

CISPLATIN; DOXORUBICIN; HEPARIN; NAVELBINE; TRASTUZUMAB;

ABDOMINAL PAIN; ADOLESCENT; ADULT; ADVANCED CANCER; AGED; ANEMIA; ANOREXIA; ARTICLE; BONE PAIN; BREAST CANCER; CLINICAL ARTICLE; CLINICAL TRIAL; COLORECTAL CANCER; CONSTIPATION; DIARRHEA; DIZZINESS; DRUG DOSE ESCALATION; DRUG DOSE INCREASE; DRUG ERUPTION; DRUG FEVER; DRUG INDUCED HEADACHE; DRUG RESPONSE; DRUG WITHDRAWAL; EDEMA; FATIGUE; FEMALE; HEAD AND NECK CANCER; HEARING LOSS; HEPATIC ARTERY; HUMAN; HYPERKALEMIA; HYPERTENSION; HYPOCALCEMIA; HYPOKALEMIA; HYPOMAGNESEMIA; HYPONATREMIA; INFECTION; KIDNEY FAILURE; LEIOMYOSARCOMA; LIVER CELL CARCINOMA; LIVER METASTASIS; LIVER TOXICITY; LOW DRUG DOSE; MALE; MAXIMUM TOLERATED DOSE; MELANOMA; MUCOSA INFLAMMATION; MULTIPLE CYCLE TREATMENT; MYALGIA; NAUSEA AND VOMITING; NEUROENDOCRINE TUMOR; NEUROPATHY; NEUTROPENIA; OVERALL SURVIVAL; PANCREAS CANCER; PHASE 1 CLINICAL TRIAL; PRIORITY JOURNAL; PROGRESSION FREE SURVIVAL; STOMACH CANCER; THROMBOCYTOPENIA; TINNITUS; TUMOR REGRESSION;

ADOLESCENT; ADULT; ANTINEOPLASTIC COMBINED CHEMOTHERAPY PROTOCOLS; BREAST NEOPLASMS; CARCINOMA, HEPATOCELLULAR; CISPLATIN; DISEASE-FREE SURVIVAL; DOXORUBICIN; DRUG ADMINISTRATION SCHEDULE; EYE NEOPLASMS; FEMALE; HEPATIC ARTERY; HUMANS; INFUSIONS, INTRA-ARTERIAL; INFUSIONS, INTRAVENOUS; KAPLAN-MEIER ESTIMATE; LIVER NEOPLASMS; MALE; MAXIMUM TOLERATED DOSE; MELANOMA; MIDDLE AGED; TREATMENT OUTCOME;

EID: 78149415403     PISSN: 03445704     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00280-010-1266-4     Document Type: Article

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