Hepatic chemoembolization combined with systemic infusion of 5- fluorouracil and bolus leucovorin for patients with metastatic colorectal carcinoma: A southwest oncology group pilot trial

Cancer

Volumn 86, Issue 5, 1999, Pages 775-781

  Leichman, Cynthia Gail ^a   Jacobson, Joth R ^b   Modiano, Manuel ^c   Daniels, John R ^d   Zalupski, Mark M ^e   Doroshow, James H ^f   Fletcher, William S ^g   Macdonald, John S ^h  

^a ROSWELL PARK CANCER INSTITUTE   (United States)

^b Fred Hutchinson Cancer Research Center   (United States)

^c Arizona Oncology Associates   (United States)

^d UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

^e WAYNE STATE UNIVERSITY   (United States)

^f CITY OF HOPE NATIONAL MEDICAL CENTER   (United States)

^g OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

^h ST VINCENT S COMPREHENSIVE CANCER CENTER   (United States)

Author keywords

5 fluorouracil; Disseminated colorectal carcinoma; Pilot study; Systemic chemotherapy

Indexed keywords

ALKALINE PHOSPHATASE; AMINOTRANSFERASE; BILIRUBIN; CARCINOEMBRYONIC ANTIGEN; CISPLATIN; DOXORUBICIN; FLUOROURACIL; FOLINIC ACID; MITOMYCIN C;

ABDOMINAL PAIN; ADULT; ADVANCED CANCER; AGED; ARTICLE; ARTIFICIAL EMBOLISM; CHEMOTHERAPY; CLINICAL ARTICLE; CLINICAL TRIAL; COLORECTAL CARCINOMA; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DISEASE COURSE; FEMALE; HUMAN; HYPERBILIRUBINEMIA; INTRAARTERIAL DRUG ADMINISTRATION; LIVER METASTASIS; LIVER TOXICITY; MALE; PATIENT SELECTION; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; SURVIVAL RATE; TREATMENT OUTCOME; TREATMENT PLANNING;

ADULT; AGED; ANTINEOPLASTIC COMBINED CHEMOTHERAPY PROTOCOLS; CHEMOEMBOLIZATION, THERAPEUTIC; CISPLATIN; COLORECTAL NEOPLASMS; COMBINED MODALITY THERAPY; DOXORUBICIN; FEASIBILITY STUDIES; FEMALE; FLUOROURACIL; HEPATIC ARTERY; HUMANS; INFUSIONS, INTRAVENOUS; LEUCOVORIN; LIVER NEOPLASMS; MALE; MIDDLE AGED; MITOMYCIN; PILOT PROJECTS; SURVIVAL ANALYSIS;

EID: 0033197982     PISSN: 0008543X     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1097-0142(19990901)86:5<775::AID-CNCR12>3.0.CO;2-M     Document Type: Article

References (23)

1. Parker SL, Tong T, Bolden S, Wingo PA. Cancer statistics, 1997. CA Cancer J Clin 1977;47:5-27.
2. Cohen AM, Minsky BD, Schilsky RL. Cancer of the colon. In: DeVita VT, Hellman S, Rosenberg SA, editors. Cancer: principles and practice of oncology. 5th edition. Philadelphia: Lippencott-Raven, 1997:1155-66.
3. Poon MA, O'Connell MJ, Moertel CG, Wieand HS, Cullinen SA, Everson LK, et al. Biochemical modulation of fluorouracil: evidence of significant improvement of survival and quality of life in patients with advanced colorectal carcinoma. J Clin Oncol 1989;7:1407-17.
4. Petrelli N, Douglass HO, Herrera L, Russell D, Stablein DM, Bruckner HW, et al. The modulation of fluorouracil with leucovorin in metastatic colorectal cancer: a prospective randomized phase III trial. J Clin Oncol 1989;7: 1419-26.
5. Lokich JJ, Ahlgren JD, Gullo JJ, Philips JA, Fryer JG. A prospective randomized comparison of continuous infusion fluorouracil with a conventional bolus schedule in metastatic colorectal carcinoma: a mid-Atlantic oncology program study. J Clin Oncol 1989;7:425-32.
6. Marsh JC, Bertino JR, Katz KH, Davis CA, Durivage HJ, Rome LS, et al. The influence of drug interval on the effect of methotrexate and fluorouracil in the treatment of advanced colorectal cancer. J Clin Oncol 1991;9:371-80.
7. Leichman CG, Flemming T, Muggia FM, Tangen C, Ardalen B, Doroshow JH, et al. Phase II study of fluorouracil and its modulation in advanced colorectal cancer: a Southwest Oncology Group study. J Clin Oncol 1995;13:1303-11.
8. Kemeny N, Daly J, Reichman B, Geller N, Botet J, Oderman P. Intrahepatic or systemic infusion of fluorodeoxyuridine in patients with liver metastases from colorectal carcinoma: a randomized trial. Ann Intern Med 1987;107:459-65.
9. Chang AE, Schneider PD, Sugarbaker PH, Simpson C, Culnane M, Steinberg SM. A prospective randomized trial of regional versus systemic continuous 5-FU chemotherapy for the treatment of colorectal metastases. Ann Surg 1987;206: 685-93.
10. Hohn DC, Stagg RJ, Friedman MA, Hannigan JF Jr., Rayner A, Ignoffo RJ, et al. A randomized trial of continuous intravenous versus hepatic intra-arterial floxuridine in patients with colorectal cancer metastatic to the liver: the Northern California oncology group trial. J Clin Oncol 1989;7:1646-54.
11. Rougier PL, Laplanche A, Huguier M, Hay JM, Ollivier JM, Escat J, et al. Hepatic arterial infusion of floxuridine in patients with liver metastases from colorectal carcinoma: long term results of a prospective randomized trial. J Clin Oncol 1992;10:1112-8.
12. Breedis C, Young KG. The blood supply of neoplasms of the liver. Am J Pathol 1954; 30:969-85.
13. Healy JE, Sheena KS. Vascular patterns in metastatic liver tumors. Surg Forum 1963;14:121-2.
14. Collins JM. Pharmacologic rationale for regional drug delivery. J Clin Oncol 1984;2:498-504.
15. Daniels JR, Sternlicht M, Daniels AM. Collagen chemoembolization: pharmacokinetics and tissue tolerance of cisplatin in liver and kidney. Cancer Res 1988;48:2446.
16. Konno T, Kai Y, Yamashita R, Nagamitsu A, Kimura M. Targeted chemotherapy for undetectable primary and metastatic liver cancer. Acta Oncol 1994;33;133-7.
17. Lang E, Brown CL. Colorectal metastases to the liver: selective chemoembolization. Radiology 1993;1189:417-22.
18. Sanz-Altamira PM, Spence LD, Huberman MS, Posner MR, Steele G Jr., Perry LJ, et al. Selective chemoembolization in the management of hepatic metastases in refractory colorectal carcinoma. Dis Colon Rectum 1997;40:770-5.
19. Daniels JR, Kerlan R, Dodds L, McLaughlin P, LaBerge J, Harrington D, et al. Peripheral hepatic arterial embolization with cross linked collagen fibrils. Invest Radiol 1987; 22:126.
20. Leichman CG, Leichman L, Spears CP, Rosen P, Jeffers S. Phase II study of prolonged infusion 5-fluorouracil with weekly leucovorin in disseminated colorectal cancer. J Natl Cancer Inst 1993;85:41-4.
21. Rougier P, Van Cutsem E, Bajetta E, Niederle N, Possinger K, Labianca R, et al. Randomised trial of irinotecan versus fluorouracil by continuous infusion after fluorouracil failure in patients with metastatic colorectal cancer. Lancet 1998; 352:1407-12.
22. Andre T, Louvet C, Raymond E, Tournigand C, de Gramont A. Bimonthly high-dose leucovorin, 5-fluorouracil infusion and oxaliplatin (FOLFOX3) for metastatic colorectal cancer resistant to the same leucovorin and 5-fluorouracil regimen. Ann Oncol 1998;11:1251-3.
23. Tellez C, Benson AB III, Lyster MT, Talamonti M, Shaw J, Braun MA, et al: Phase II trial of chemoembolization for the treatment of metastatic colorectal carcinoma to the liver and review of the literature. Cancer 1998;82:1250-9.