In vivo target recognition with high-resolution imaging: Significance for drug development

European Journal of Drug Metabolism and Pharmacokinetics

Volumn 35, Issue 1-2, 2010, Pages 15-22

  Stumpf, Walter E ^a  

^a UNIVERSITY OF NORTH CAROLINA   (United States)

Author keywords

ADME; Arndt Schulz rule; Autoradiography; Drug homunculus; Drug localization; Histopharmacology; Hormesis; Imaging; Receptor; Vitamin D

Indexed keywords

CARBON 14; COLECALCIFEROL; TRITIUM; VITAMIN D; VITAMIN D RECEPTOR;

ARTICLE; AUTORADIOGRAPHY; CANCER INHIBITION; CELL DENSITY; CELLULAR DISTRIBUTION; DOSE RESPONSE; DRUG DISTRIBUTION; DRUG MECHANISM; DRUG MEGADOSE; DRUG RESEARCH; DRUG TARGETING; HIGH RESOLUTION MICROSCOPIC AUTORADIOGRAPHY; IN VIVO STUDY; INTERMETHOD COMPARISON; ISOTOPE LABELING; LOW DRUG DOSE; NONHUMAN; PREDICTION; PSORIASIS; RADIOACTIVITY; RADIOASSAY; SENSITIVITY AND SPECIFICITY; TARGET CELL; WHOLE BODY AUTORADIOGRAPHY;

EID: 78149412849     PISSN: 03787966     EISSN: 21070180     Source Type: Journal    
DOI: 10.1007/s13318-010-0003-z     Document Type: Article

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