메뉴 건너뛰기




Volumn 22, Issue 11, 2010, Pages 586-592

Oral 5-aminosalicylic acid therapy for mild-to-moderate ulcerative colitis

Author keywords

Gastroenterology; Gastrointestinal; Inflammatory bowel disease; Nurse practitioners; Ulcerative colitis

Indexed keywords

MESALAZINE; NONSTEROID ANTIINFLAMMATORY AGENT;

EID: 78149338647     PISSN: 10412972     EISSN: 17457599     Source Type: Journal    
DOI: 10.1111/j.1745-7599.2010.00558.x     Document Type: Review
Times cited : (2)

References (51)
  • 1
    • 0025329655 scopus 로고
    • Clinical evidence supporting the radical scavenger mechanism of 5-aminosalicylic acid
    • Ahnfelt-Ronne, I., Nielsen, O. H., Christensen, A., Langholz, E., Binder, V., & Riis, P. (1990). Clinical evidence supporting the radical scavenger mechanism of 5-aminosalicylic acid. Gastroenterology, 98(5 Pt 1), 1162-1169.
    • (1990) Gastroenterology , vol.98 , Issue.5 PART 1 , pp. 1162-1169
    • Ahnfelt-Ronne, I.1    Nielsen, O.H.2    Christensen, A.3    Langholz, E.4    Binder, V.5    Riis, P.6
  • 2
    • 78149355792 scopus 로고    scopus 로고
    • Apriso product information. Retrieved March 20, 2009, from
    • Apriso product information. (2009). Retrieved March 20, 2009, from
    • (2009)
  • 4
    • 38849151015 scopus 로고    scopus 로고
    • An innovative role for nurse practitioners in managing chronic disease
    • Boville, D., Saran, M., Salem, J. K., Clough, L., Jones, R. R., Radwany, S. M., et al. (2007). An innovative role for nurse practitioners in managing chronic disease. Nursing Economics, 25(6), 359-364.
    • (2007) Nursing Economics , vol.25 , Issue.6 , pp. 359-364
    • Boville, D.1    Saran, M.2    Salem, J.K.3    Clough, L.4    Jones, R.R.5    Radwany, S.M.6
  • 5
    • 0037215289 scopus 로고    scopus 로고
    • Molecular underpinnings of cancer in ulcerative colitis
    • Brentnall, T. A. (2003). Molecular underpinnings of cancer in ulcerative colitis. Current Opinions in Gastroenterology, 19(1), 64-68.
    • (2003) Current Opinions in Gastroenterology , vol.19 , Issue.1 , pp. 64-68
    • Brentnall, T.A.1
  • 6
    • 4344602852 scopus 로고    scopus 로고
    • Guidelines for the management of inflammatory bowel disease in adults
    • Carter, M. J., Lobo, A. J., & Travis, S. P. (2004). Guidelines for the management of inflammatory bowel disease in adults. Gut, 53(Suppl. V), V1-V16.
    • (2004) Gut , vol.53 , Issue.SUPPL. 5
    • Carter, M.J.1    Lobo, A.J.2    Travis, S.P.3
  • 8
    • 0036885593 scopus 로고    scopus 로고
    • Evaluating emergency nurse practitioner services: A randomized controlled trial
    • Cooper, M. A., Lindsay, G. M., Kinn, S., & Swann, I. J. (2002). Evaluating emergency nurse practitioner services: A randomized controlled trial. Journal of Advanced Nursing, 40(6), 721-730.
    • (2002) Journal of Advanced Nursing , vol.40 , Issue.6 , pp. 721-730
    • Cooper, M.A.1    Lindsay, G.M.2    Kinn, S.3    Swann, I.J.4
  • 9
    • 78149308938 scopus 로고    scopus 로고
    • Crohn's and Colitis Foundation of America (CCFA), What is IBD? possible complications. Retrieved May 15, 2009, from
    • Crohn's and Colitis Foundation of America (CCFA). (2007) What is IBD? possible complications. Retrieved May 15, 2009, from
    • (2007)
  • 11
    • 0034893382 scopus 로고    scopus 로고
    • Mesalazine 4 g daily given as prolonged-release granules twice daily and four times daily is at least as effective as prolonged-release tablets four times daily in patients with ulcerative colitis
    • Farup, P., Hinterleitner, T., Lukas, M., Hebuterne, X., Rachmilewitz, D., Campieri, M., et al. (2001). Mesalazine 4 g daily given as prolonged-release granules twice daily and four times daily is at least as effective as prolonged-release tablets four times daily in patients with ulcerative colitis. Inflammatory Bowel Diseases, 7(3), 237-242.
    • (2001) Inflammatory Bowel Diseases , vol.7 , Issue.3 , pp. 237-242
    • Farup, P.1    Hinterleitner, T.2    Lukas, M.3    Hebuterne, X.4    Rachmilewitz, D.5    Campieri, M.6
  • 12
    • 40649118801 scopus 로고    scopus 로고
    • Living with chronic illness: A phenomenological study of the health effects of the patient-provider relationship
    • Fox, S., & Chesla, C. (2008). Living with chronic illness: A phenomenological study of the health effects of the patient-provider relationship. Journal of the American Academy of Nurse Practitioner, 20(3), 109-117.
    • (2008) Journal of the American Academy of Nurse Practitioner , vol.20 , Issue.3 , pp. 109-117
    • Fox, S.1    Chesla, C.2
  • 15
    • 34347323860 scopus 로고    scopus 로고
    • Medication beliefs among patients with inflammatory bowel disease who report low quality of life: A qualitative study
    • Hall, N. J., Rubin, G. P., Hungin, A. P., & Dougall, A. (2007). Medication beliefs among patients with inflammatory bowel disease who report low quality of life: A qualitative study. BMC Gastroenterology, 7, 20.
    • (2007) BMC Gastroenterology , vol.7 , pp. 20
    • Hall, N.J.1    Rubin, G.P.2    Hungin, A.P.3    Dougall, A.4
  • 16
    • 13944271403 scopus 로고    scopus 로고
    • Predictors of quality of life in ulcerative colitis: The importance of symptoms and illness representations
    • Han, S. W., McColl, E., Barton, J. R., James, P., Steen, I. N., & Welfare, M. R. (2005). Predictors of quality of life in ulcerative colitis: The importance of symptoms and illness representations. Inflammatory Bowel Diseases, 11(1), 24-34.
    • (2005) Inflammatory Bowel Diseases , vol.11 , Issue.1 , pp. 24-34
    • Han, S.W.1    McColl, E.2    Barton, J.R.3    James, P.4    Steen, I.N.5    Welfare, M.R.6
  • 17
    • 39149118880 scopus 로고    scopus 로고
    • Delayed-release oral mesalamine 4.8 g/day (800 mg tablets) compared to 2.4 g/day (400 mg tablets) for the treatment of mildly to moderately active ulcerative colitis: The ASCEND I trial
    • Hanauer, S. B., Sandborn, W. J., Dallaire, C., Archambault, A., Yacyshyn, B., Yeh, C., et al. (2007). Delayed-release oral mesalamine 4.8 g/day (800 mg tablets) compared to 2.4 g/day (400 mg tablets) for the treatment of mildly to moderately active ulcerative colitis: The ASCEND I trial. Canadian Journal of Gastroenterology, 21(12), 827-834.
    • (2007) Canadian Journal of Gastroenterology , vol.21 , Issue.12 , pp. 827-834
    • Hanauer, S.B.1    Sandborn, W.J.2    Dallaire, C.3    Archambault, A.4    Yacyshyn, B.5    Yeh, C.6
  • 18
    • 33644653559 scopus 로고    scopus 로고
    • Delayed-release oral mesalamine at 4.8 g/day (800 mg tablet) for the treatment of moderately active ulcerative colitis: The ASCEND II trial
    • Hanauer, S. B., Sandborn, W. J., Kornbluth, A., Katz, S., Safdi, M., Woogen, S., et al. (2005). Delayed-release oral mesalamine at 4.8 g/day (800 mg tablet) for the treatment of moderately active ulcerative colitis: The ASCEND II trial. American Journal of Gastroenterology, 100(11), 2478-2485.
    • (2005) American Journal of Gastroenterology , vol.100 , Issue.11 , pp. 2478-2485
    • Hanauer, S.B.1    Sandborn, W.J.2    Kornbluth, A.3    Katz, S.4    Safdi, M.5    Woogen, S.6
  • 20
    • 4844226455 scopus 로고    scopus 로고
    • Review article: Patients' fears and unmet needs in inflammatory bowel disease
    • Irvine, E. J. (2004). Review article: Patients' fears and unmet needs in inflammatory bowel disease. Alimentary Pharmacology & Therapeutics, 20(Suppl. 4), 54-59.
    • (2004) Alimentary Pharmacology & Therapeutics , vol.20 , Issue.SUPPL. 4 , pp. 54-59
    • Irvine, E.J.1
  • 22
    • 0033047588 scopus 로고    scopus 로고
    • Mesalamine blocks tumor necrosis factor growth inhibition and nuclear factor kappaB activation in mouse colonocytes
    • Kaiser, G. C., Yan, F., & Polk, D. B. (1999). Mesalamine blocks tumor necrosis factor growth inhibition and nuclear factor kappaB activation in mouse colonocytes. Gastroenterology, 116(3), 602-609.
    • (1999) Gastroenterology , vol.116 , Issue.3 , pp. 602-609
    • Kaiser, G.C.1    Yan, F.2    Polk, D.B.3
  • 25
    • 33644995445 scopus 로고    scopus 로고
    • Systematic review: Adherence issues in the treatment of ulcerative colitis
    • Kane, S. V. (2006). Systematic review: Adherence issues in the treatment of ulcerative colitis. Alimentary Pharmacology & Therapeutics, 23(5), 577-585.
    • (2006) Alimentary Pharmacology & Therapeutics , vol.23 , Issue.5 , pp. 577-585
    • Kane, S.V.1
  • 26
    • 39549091909 scopus 로고    scopus 로고
    • The challenge of compliance and persistence: Focus on ulcerative colitis
    • Kane, S. V., Brixner, D., Rubin, D. T., & Sewitch, M. J. (2008). The challenge of compliance and persistence: Focus on ulcerative colitis. Journal of Managed Care Pharmacy, 14(1 Suppl. A), s2-s12.
    • (2008) Journal of Managed Care Pharmacy , vol.14 , Issue.1 SUPPL. A
    • Kane, S.V.1    Brixner, D.2    Rubin, D.T.3    Sewitch, M.J.4
  • 28
    • 0037245392 scopus 로고    scopus 로고
    • Medication nonadherence and the outcomes of patients with quiescent ulcerative colitis
    • Kane, S., Huo, D., Aikens, J., & Hanauer, S. (2003). Medication nonadherence and the outcomes of patients with quiescent ulcerative colitis. American Journal of Medicine, 114(1), 39-43.
    • (2003) American Journal of Medicine , vol.114 , Issue.1 , pp. 39-43
    • Kane, S.1    Huo, D.2    Aikens, J.3    Hanauer, S.4
  • 29
    • 3843109109 scopus 로고    scopus 로고
    • Ulcerative colitis practice guidelines in adults (update): American College of Gastroenterology, Practice Parameters Committee
    • Kornbluth, A., & Sachar, D. B. (2004). Ulcerative colitis practice guidelines in adults (update): American College of Gastroenterology, Practice Parameters Committee. American Journal of Gastroenterology, 99(7), 1371-1385.
    • (2004) American Journal of Gastroenterology , vol.99 , Issue.7 , pp. 1371-1385
    • Kornbluth, A.1    Sachar, D.B.2
  • 30
    • 0042060937 scopus 로고    scopus 로고
    • The case for nurse practitioners. Used correctly, they can improve outcomes, lower costs and make up for reduced residents' hours
    • 2.
    • Larkin, H. (2003). The case for nurse practitioners. Used correctly, they can improve outcomes, lower costs and make up for reduced residents' hours. Hospitals and Health Networks, 77(8), 54-58, 2.
    • (2003) Hospitals and Health Networks , vol.77 , Issue.8 , pp. 54-58
    • Larkin, H.1
  • 31
    • 36049014556 scopus 로고    scopus 로고
    • A randomized, placebo-controlled trial of the PPAR-gamma ligand rosiglitazone for active ulcerative colitis
    • Abstract 639a
    • Lewis, J. D., Lichtenstein, G. R., Deren, J. J., Sands, B. E., Hanauer, S. B., Katz, J. A., et al. (2007). A randomized, placebo-controlled trial of the PPAR-gamma ligand rosiglitazone for active ulcerative colitis. Gastroenterology, 13 (24, Suppl. 1), (Abstract 639a).
    • (2007) Gastroenterology , vol.13 , Issue.24 SUPPL. 1
    • Lewis, J.D.1    Lichtenstein, G.R.2    Deren, J.J.3    Sands, B.E.4    Hanauer, S.B.5    Katz, J.A.6
  • 32
    • 33846242590 scopus 로고    scopus 로고
    • Effect of once- or twice-daily MMX mesalamine (SPD476) for the induction of remission of mild to moderately active ulcerative colitis
    • Lichtenstein, G. R., Kamm, M. A., Boddu, P., Gubergrits, N., Lyne, A., Butler, T., et al. (2007). Effect of once- or twice-daily MMX mesalamine (SPD476) for the induction of remission of mild to moderately active ulcerative colitis. Clinical Gastroenterology and Hepatology, 5, 95-102.
    • (2007) Clinical Gastroenterology and Hepatology , vol.5 , pp. 95-102
    • Lichtenstein, G.R.1    Kamm, M.A.2    Boddu, P.3    Gubergrits, N.4    Lyne, A.5    Butler, T.6
  • 33
    • 4644267065 scopus 로고    scopus 로고
    • Controversies with aminosalicylates in inflammatory bowel disease
    • Lim, W. C., & Hanauer, S. B. (2004). Controversies with aminosalicylates in inflammatory bowel disease. Reviews in Gastroenterological Disorders, 4(3), 104-117.
    • (2004) Reviews in Gastroenterological Disorders , vol.4 , Issue.3 , pp. 104-117
    • Lim, W.C.1    Hanauer, S.B.2
  • 34
    • 0043175283 scopus 로고    scopus 로고
    • Physician - nurse practitioner teams in chronic disease management: The impact on costs, clinical effectiveness, and patients' perception of care
    • Litaker, D., Mion, L., Planavsky, L., Kippes, C., Mehta, N., & Frolkis, J. (2003). Physician - nurse practitioner teams in chronic disease management: The impact on costs, clinical effectiveness, and patients' perception of care. Journal of Interprofessional Care, 17(3), 223-237.
    • (2003) Journal of Interprofessional Care , vol.17 , Issue.3 , pp. 223-237
    • Litaker, D.1    Mion, L.2    Planavsky, L.3    Kippes, C.4    Mehta, N.5    Frolkis, J.6
  • 35
    • 33751574430 scopus 로고    scopus 로고
    • A practical perspective on ulcerative colitis: Patients' needs from aminosalicylate therapies
    • Loftus, E. V., Jr. (2006). A practical perspective on ulcerative colitis: Patients' needs from aminosalicylate therapies. Inflammatory Bowel Diseases, 12(12), 1107-1113.
    • (2006) Inflammatory Bowel Diseases , vol.12 , Issue.12 , pp. 1107-1113
    • Loftus Jr, E.V.1
  • 36
    • 34250878778 scopus 로고    scopus 로고
    • Prognostic significance of endoscopy remission in patients with active ulcerative colitis treated with oral and topical mesalazine: Preliminary results of a prospective, multicenter study
    • Abstract S1302
    • Meucci, G., Fasoli, R., Saibeni, S., Valpiani, D., Gullotta, R., Colombo, E., et al. (2006). Prognostic significance of endoscopy remission in patients with active ulcerative colitis treated with oral and topical mesalazine: Preliminary results of a prospective, multicenter study. Gastroenterology, 130 A-197 (Abstract S1302).
    • (2006) Gastroenterology , vol.130
    • Meucci, G.1    Fasoli, R.2    Saibeni, S.3    Valpiani, D.4    Gullotta, R.5    Colombo, E.6
  • 38
    • 78149312071 scopus 로고    scopus 로고
    • National Digestive Diseases Information Clearinghouse. Ulcerative colitis. Retrieved May 15, 2009, from
    • National Digestive Diseases Information Clearinghouse. (2007). Ulcerative colitis. Retrieved May 15, 2009, from
    • (2007)
  • 40
    • 0019037191 scopus 로고
    • Evaluating nurse practitioner performance
    • passim.
    • Prescott, P. A., & Driscoll, L. (1980). Evaluating nurse practitioner performance. Nurse Practitioner, 5(4), 28-2, passim.
    • (1980) Nurse Practitioner , vol.5 , Issue.4 , pp. 28-32
    • Prescott, P.A.1    Driscoll, L.2
  • 41
    • 20944445862 scopus 로고    scopus 로고
    • Intestinal antiinflammatory effect of 5-aminosalicylic acid is dependent on peroxisome proliferator-activated receptor-gamma
    • Rousseaux, C., Lefebvre, B., Dubuquoy, L., Lefebvre, P., Romano, O., Auwerx, J., et al. (2005). Intestinal antiinflammatory effect of 5-aminosalicylic acid is dependent on peroxisome proliferator-activated receptor-gamma. Journal of Experimental Medicine, 201(8), 1205-1215.
    • (2005) Journal of Experimental Medicine , vol.201 , Issue.8 , pp. 1205-1215
    • Rousseaux, C.1    Lefebvre, B.2    Dubuquoy, L.3    Lefebvre, P.4    Romano, O.5    Auwerx, J.6
  • 42
    • 34250883817 scopus 로고    scopus 로고
    • ®) mesalazine for the induction of remission in patients with mild-to-moderate ulcerative colitis: A combined analysis of two randomized, double-blind, placebo-controlled trials
    • ®) mesalazine for the induction of remission in patients with mild-to-moderate ulcerative colitis: A combined analysis of two randomized, double-blind, placebo-controlled trials. Alimentary Pharmacology & Therapeutics, 26(2), 205-215.
    • (2007) Alimentary Pharmacology & Therapeutics , vol.26 , Issue.2 , pp. 205-215
    • Sandborn, W.J.1    Kamm, M.A.2    Lichtenstein, G.R.3    Lyne, A.4    Butler, T.5    Joseph, R.E.6
  • 43
    • 54049153890 scopus 로고    scopus 로고
    • Efficacy and safety of delayed-release oral mesalamine at 4.8 g/D (800 mg tablet) in the treatment of moderately active ulcerative colitis: Results of the Ascend III study
    • Abstract 702
    • Sandborn, W. J., Regula, J., Faegan, B., Belousova, E. A., Jojic, N. V., Lucas, M., et al. (2008). Efficacy and safety of delayed-release oral mesalamine at 4.8 g/D (800 mg tablet) in the treatment of moderately active ulcerative colitis: Results of the Ascend III study. Gastroenterology, 134(4 Suppl. 1), A-99 (Abstract 702).
    • (2008) Gastroenterology , vol.134 , Issue.4 SUPPL. 1
    • Sandborn, W.J.1    Regula, J.2    Faegan, B.3    Belousova, E.A.4    Jojic, N.V.5    Lucas, M.6
  • 46
    • 84982333870 scopus 로고
    • Salazopyrin, a new sulfanilamide preparation. A. Therapeutic results in rheumatic polyarthritis. B. Therapeutic results in ulcerative colitis. C. Toxic manifestations in treatment with sulphanilamide preparations
    • Svartz, N. (1942). Salazopyrin, a new sulfanilamide preparation. A. Therapeutic results in rheumatic polyarthritis. B. Therapeutic results in ulcerative colitis. C. Toxic manifestations in treatment with sulphanilamide preparations. Acta Medica Scandinavica (110), 577-598.
    • (1942) Acta Medica Scandinavica , vol.110 , pp. 577-598
    • Svartz, N.1
  • 47
    • 38449090138 scopus 로고    scopus 로고
    • Release of 5-aminosalicylate from the MMX™ mesalamine tablet during transit through a simulated gastrointestinal tract system
    • Tenjarla, S., Romasanta, V., Zeijdner, E., Villa, R., & Moro, L. (2007). Release of 5-aminosalicylate from the MMX™ mesalamine tablet during transit through a simulated gastrointestinal tract system. Advances in Therapy, 24(4), 826-840.
    • (2007) Advances in Therapy , vol.24 , Issue.4 , pp. 826-840
    • Tenjarla, S.1    Romasanta, V.2    Zeijdner, E.3    Villa, R.4    Moro, L.5
  • 48
    • 34250652077 scopus 로고    scopus 로고
    • Take your medicine": Nonadherence issues in patients with ulcerative colitis
    • Turnbough, L., & Wilson, L. (2007). "Take your medicine": Nonadherence issues in patients with ulcerative colitis. Gastroenterology Nursing, 30(3), 212-217.
    • (2007) Gastroenterology Nursing , vol.30 , Issue.3 , pp. 212-217
    • Turnbough, L.1    Wilson, L.2
  • 49
    • 15444372803 scopus 로고    scopus 로고
    • Preventing neoplastic progression in ulcerative colitis
    • Ullman, T. A. (2005). Preventing neoplastic progression in ulcerative colitis. Journal of Clinical Gastroenterology., 39(4 Suppl. 2), S66-S69.
    • (2005) Journal of Clinical Gastroenterology. , vol.39 , Issue.4 SUPPL. 2
    • Ullman, T.A.1
  • 50
    • 20344373190 scopus 로고    scopus 로고
    • Effects of formal education for patients with inflammatory bowel disease: A randomized controlled trial
    • Waters, B. M., Jensen, L., & Fedorak, R. N. (2005). Effects of formal education for patients with inflammatory bowel disease: A randomized controlled trial. Canadian Journal of Gastroenterology, 19(4), 235-244.
    • (2005) Canadian Journal of Gastroenterology , vol.19 , Issue.4 , pp. 235-244
    • Waters, B.M.1    Jensen, L.2    Fedorak, R.N.3
  • 51
    • 78149336194 scopus 로고    scopus 로고
    • World Health Organization. Adherence to long-term therapies. Evidence for action. Retrieved May 2009 from
    • World Health Organization (2003). Adherence to long-term therapies. Evidence for action. Retrieved May 2009 from
    • (2003)


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.