Synthesis and circular dichroism of optically active 1,3-disubstituted isochromans of dopamine D4 antagonist activity

Tetrahedron Asymmetry

Volumn 21, Issue 19, 2010, Pages 2356-2360

  Kerti, Gábor ^a   Kurtán, Tibor ^a   Kövér, Katalin E ^a   Sólyom, Sándor ^b   Greiner, István ^c   Antus, Sándor ^a,d  

^a UNIVERSITY OF DEBRECEN   (Hungary)

^b TEVA PHARMACEUTICALS   (Israel)

^c GEDEON RICHTER LTD   (Hungary)

^d INSTITUTE OF EXPERIMENTAL MEDICINE   (Hungary)

Author keywords

[No Author keywords available]

Indexed keywords

1 [2 [4 (4 METHOXYPHENYL) 1 PIPERAZINYL]ETHYL] N METHYLISOCHROMAN 6 CARBOXAMIDE; 1 AMINOMETHYL 5,6 DIHYDROXY 3 PHENYLISOCHROMAN; 6,7 DIMETHOXY 3 METHYL 3,4 DIHYDRO 1H ISOCHROMEN 1 YL ACETIC ACID; 6,7 DIMETHOXY 3 METHYL 3,4 DIHYDRO 1H ISOCHROMEN 1 YL ACETYL 4 (4 METHOXYPHENYL)PIPERAZINE; 6,7 DIMETHOXY 3 METHYL 3,4 DIHYDRO 1H ISOCHROMEN 1 YL ETHYL 4 (4 METHOXYPHENYL)PIPERAZINE; DOPAMINE 4 RECEPTOR; ETHYL [ 6,7 DIMETHOXY 3 METHYL 3,4 DIHYDRO 1H ISOCHROMEN 1 YL]ACETATE; ETHYL [6,7 DIMETHOXY 3 METHYL 3,4 DIHYDRO 1H ISOCHROMEN 1 YL]ACETATE; HALOPERIDOL; ISOCHROMAN DERIVATIVE; SONEPIPRAZOLE; SPIPERONE; UNCLASSIFIED DRUG;

ARTICLE; CHO CELL; CHROMATOPHORE; CIRCULAR DICHROISM; CONFORMATIONAL TRANSITION; DOPAMINERGIC ACTIVITY; DRUG SYNTHESIS; HUMAN; LIGAND BINDING; PRIORITY JOURNAL; STRUCTURE ACTIVITY RELATION;

EID: 78149285056     PISSN: 09574166     EISSN: 1362511X     Source Type: Journal    
DOI: 10.1016/j.tetasy.2010.08.006     Document Type: Article

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