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Bioorganic and Medicinal Chemistry Letters

Volumn 20, Issue 23, 2010, Pages 6978-6982

Biarylimidazoles as inhibitors of microsomal prostaglandin E2 synthase-1

(11) Wu, Tom Y H a Juteau, Hélne a Ducharme, Yves a Friesen, Richard W a Guiral, Sébastien a Dufresne, Lynn a Poirier, Hugo a Salem, Myriam a Riendeau, Denis a Mancini, Joseph a Brideau, Christine a

a MERCK FROSST CENTRE FOR THERAPEUTIC RESEARCH (Canada)

Author keywords

Biarylimidazole; Inflammation; Inhibitor; MPGES 1; PGE2

Indexed keywords

ANALGESIC AGENT; ANTIINFLAMMATORY AGENT; IMIDAZOLE DERIVATIVE; POLYCYCLIC AROMATIC HYDROCARBON DERIVATIVE; PROSTAGLANDIN E SYNTHASE 1; PROSTAGLANDIN E2;

ARTICLE; DRUG POTENCY; DRUG SELECTIVITY; ENZYMATIC ASSAY; ENZYME INHIBITION; HIGH THROUGHPUT SCREENING; HUMAN; HUMAN CELL; STRUCTURE ACTIVITY RELATION;

ANIMALS; ANTI-INFLAMMATORY AGENTS; CELL LINE; DINOPROSTONE; HIGH-THROUGHPUT SCREENING ASSAYS; IMIDAZOLES; INTRAMOLECULAR OXIDOREDUCTASES; MICE; MICROSOMES;

EID: 78149279744 PISSN: 0960894X EISSN: None Source Type: Journal
DOI: 10.1016/j.bmcl.2010.09.129 Document Type: Article

Times cited : (31)

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