α-1,6-mannosylation of N-linked oligosaccharide present on cell wall proteins is required for their incorporation into the cell wall in the filamentous fungus Neurospora crassa

Eukaryotic Cell

Volumn 9, Issue 11, 2010, Pages 1766-1775

  Maddi, Abhiram ^a   Free, Stephen J ^a  

^a UNIVERSITY AT BUFFALO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

FUNGAL DNA; FUNGAL PROTEIN; GLYCOSYLPHOSPHATIDYLINOSITOL; MANNOSYLTRANSFERASE; OLIGOSACCHARIDE;

ARTICLE; CARBOHYDRATE ANALYSIS; CELL WALL; CHEMISTRY; CONFORMATION; FUNGAL GENE; GENETIC COMPLEMENTATION; GENETICS; METABOLISM; MUTATION; NEUROSPORA CRASSA; NUCLEOTIDE SEQUENCE;

BASE SEQUENCE; CARBOHYDRATE CONFORMATION; CARBOHYDRATE SEQUENCE; CELL WALL; DNA, FUNGAL; FUNGAL PROTEINS; GENES, FUNGAL; GENETIC COMPLEMENTATION TEST; GLYCOSYLPHOSPHATIDYLINOSITOLS; MANNOSYLTRANSFERASES; MUTATION; NEUROSPORA CRASSA; OLIGOSACCHARIDES;

FUNGI; NEUROSPORA CRASSA;

EID: 78149278764     PISSN: 15359778     EISSN: None     Source Type: Journal    
DOI: 10.1128/EC.00134-10     Document Type: Article

References (38)

1. Ballou, C. E. 1990. Isolation, characterization, and properties of Saccharo-myces cerevisiae mnn mutants with nonconditional protein glycosylation defects. Methods Enzymol. 185:440-479.
2. Barnay-Verdier, S., A. Boisrame, and J.-M. Beckerick. 2004. Identification and characterization of two -1,6-mannosyltransferases, Anl1p and Och1p, in the yeast Yarrowia lipolytica. Microbiology 150:2185-2195.
3. Bates, S., H. B. Hughes, C. A. Munro, W. P. H. Thomas, D. M. MacCallum, G. Bertram, et al. 2006. Outer chain N-glycans are required for cell wall integrity and virulence of Candida albicans. J. Biol. Chem. 281:90-98.
4. Borkovich, K. A., L. A. Alex, O. Yarden, M. Freitag, G. E. Turner, N. D. Read, et al. 2004. Lessons from the genome sequences of Neurospora crassa: tracing the path from genomic blueprint to multicellular organism. Microbiol. Mol. Biol. Rev. 68:1-108.
5. Bouffard, F. A., R. A. Zambias, J. F. Dropinski, J. M. Balkovec, M. L. Hammond, G. K. Abrazzo, et al. 1994. Synthesis and antifungal activity of novel cationic pneumocandin B(o) derivatives. J. Med. Chem. 37:222-225.
6. Bowman, S. M., and S. J. Free. 2006. The structure and synthesis of the fungal cell wall. Bioessays 28:799-808.
7. Bowman, S. M., A. Piwowar, M. Al Dabbous, J. Vierula, and S. J. Free. 2006. Mutational analysis of the glycosylphosphatidylinositol (GPI) anchor pathway demonstrates that GPI-anchored proteins are required for cell wall biogenesis and normal hyphal growth in Neurospora crassa. Eukaryot. Cell 5:587-600.
8. Chaffin, W. L. 2008. Candida albicans cell wall proteins. Microbiol. Mol. Biol. Rev. 72:495-544.
9. Choi, B.-K., P. Bobrowicz, R. C. Davidson, S. R. Hamilton, D. H. Kung, H. Li, et al. 2003. Use of combinatorial genetic libraries to humanize N-linked glycosylation in the yeast Pichia pastoris. Proc. Natl. Acad. Sci. U. S. A. 100:5022-5027.
10. Colot, H. V., G. Park, G. E. Turner, C. Ringelberg, C. M. Crew, L. Litvinkova, et al. 2006. A high-throughput gene knockout procedure for Neurospora reveals functions for multiple transcription factors. Proc. Natl. Acad. Sci. U. S. A. 103:10352-10357.
11. Cullen, P. J., J. Schultz, J. Horecka, B. J. Stevenson, Y. Jigami, and G. F. Sprague. 2000. Defects in protein glycosylation cause SHO1-dependent activation of STE12 signaling pathway in yeast. Genetics 155:1005-1018.
12. Davis, R. H., and F. J. DeSerres. 1970. Genetic and microbiological research techniques for Neurospora crassa. Methods Enzymol. 27:79-143.
13. Dean, N. 1999. Asparagine-linked glycosylation in yeast Golgi. Biochim. Biophys. Acta 1426:309-322.
14. Deshpande, N., M. R. Wilkins, N. Packer, and H. Nevalainen. 2008. Protein glycosylation pathways in filamentous fungi. Glycobiology 18:626-637.
15. Fujii, T., H. Shimoni, and Y. Iimura. 1999. Structure of the glucan-binding sugar chain of Tip1p, a cell wall protein of Saccharomyces cerevisiae. Biochim. Biophys. Acta 1427:133-144.
16. Gemmill, T. R., and R. B. Trimble. 1999. Overview of N-and O-linked oligosaccharide structures found in various yeast species. Biochim. Biophys. Acta 1426:227-237.
17. Kim, M. W., E. J. Kim, J.-Y. Kim, J.-S. Park, D.-B. Oh, Y.-I. Shimma, et al. 2006. Functional characterization of the Hansenula polymorpha HOC1, OCH1, and OCR1 genes as members of the yeast OCH1 mannosyltransferase family involved in protein glycosylation. J. Biol. Chem. 281:6261-6272.
18. Lambou, K., S. Perkhofer, T. Fontaine, and J. P. Latge. 2010. Comparative functional analysis of the OCH1 mannosyltransferase families in Aspergillus fumigatus and Saccharomyces cerevisiae. Yeast 27:625-636.
19. Latge, J.-P. 2007. The cell wall: a carbohydrate armour for the fungal cell. Mol. Microbiol. 66:279-290.
20. Leal, J. A., J. Jimenez-Barbero, B. Gomez-Miranda, A. Prieto, J. Domenech, and M. Bernabe. 1996. Structural investigation of the cell-wall galactomannan from Neurospora crassa and N. sitophila. Carbohydr. Res. 283:215-222.
21. Lee, B. N., and E. A. Elion. 1999. The MAPKKK Ste11 regulates vegetative growth through a kinase cascade of shared signaling components. Proc. Natl. Acad. Sci. U. S. A. 96:12679-12684.
22. Lehle, L., A. Eiden, K. Lehnert, A. Haselbeck, and E. Kopetzki. 1995. Gly-coprotein biosynthesis in Saccharomyces cerevisiae: ngd29, an N-glycosylation mutant allelic to och1 having a defect in the initiation of outer chain formation. FEBS Lett. 370:41-45.
23. Lesage, G., and H. Bussey. 2006. Cell wall assembly in Saccharomyces cerevisiae. Microbiol. Mol. Biol. Rev. 70:317-343.
24. Levin, D. E. 2005. Cell wall integrity signaling in Saccharomyces cerevisiae. Microbiol. Mol. Biol. Rev. 69:262-291.
25. Lu, C.-F., R. C. Montijn, J. L. Brown, F. Klis, J. Kurjan, H. Bussey, and P. N. Lipke. 1995. Glycosylphosphatidylinositol-dependent cross-linking of alpha-agglutinin and beta-1,6-glucan in the Saccharomyces cerevisiae cell wall. J. Cell Biol. 128:333-340.
26. Maddi, A., S. M. Bowman, and S. J. Free. 2009. Trifluoromethansulfonic acid-based proteomic analysis of cell wall and secreted proteins of the asco-mycetous fungi Neurospora crassa and Candida albicans. Fungal Genet. Biol. 46:768-781.
27. Maniatis, T., E. F. Fritsch, and C. Sambrook. 1982. Molecular cloning: a laboratory manual. Cold Spring Harbor Press, Cold Spring Harbor, NY.
28. Margolin, B. S., M. Freitag, and E. U. Selker. 1997. Improved plasmids for gene targeting at the his-3 locus of Neurospora crassa. Fungal Genet. Newsl. 44:34-36.
29. Mouyna, I., T. Fontaine, M. Vai, M. Monod, W. A. Fonzi, M. Diaquin, et al. 2000. Glycosylphosphatidylinositol-anchored glucanosyltransferases play an active role in the biosynthesis of the fungal cell wall. J. Biol. Chem. 275: 14882-14889.
30. Munro, S. 2001. What can yeast tell us about N-linked glycosylation in the Golgi apparatus? FEBS Lett. 498:223-227.
31. Nakajima, T., M. Yoshida, N. Hura, and K. Matsuda. 1984. Structure of the cell wall proteogalactomannan from Neurospora crassa. I. Purification of the proteoheteroglycan and characterization of alkali-labile oligosaccharides. J. Biochem. 96:1005-1011.
32. Nakajima, T., M. Yoshida, M. Nakamura, N. Hura, and K. Matsuda. 1984. Structure of the cell wall proteogalactomannan from Neurospora crassa. II. Structural analysis of the polysaccharide part. J. Biochem. 96:1013-1020.
33. Nakanishi-Shindo, Y., K. Nakayama, A. Tanaka, Y. Toda, and Y. Jigami. 1993. Structure of the N-linked oligosaccharides that show the complete loss of -1,6-polymannose outer chain from och1, och1 mnn1, and mnn1 alg3 mutants of Saccharomyces cerevisiae. J. Biol. Chem. 268:26338-26345.
34. Nakayama, K., T. Nagasu, Y. Shimma, J. Kuromitsu, and Y. Jigami. 1992. OCH1 encodes a novel membrane bound mannosyltransferase: outer chain elongation of asparagines-linked oligosaccharides. EMBO J. 11: 2511-2519.
35. Ohashi, T., Y. Ikeda, N. Tanaka, S. Nakakita, S. Natsuka, Y. Giga-Hama, and K. Takegawa. 2009. The och1 mutant of Schizosaccharomyces pombe produces galactosylated core structures of N-linked oligosaccharides. Biosci. Biotechnol. Biochem. 73:4070-4414.
36. Scrimale, T., L. Didone, K. L. de Mesy Bentley, and D. J. Krysan. 2009. The unfolded protein response is induced by the cell wall integrity mitogen-activated protein kinase signaling cascade and is required for cell wall integrity in Saccharomyces cerevisiae. Mol. Biol. Cell 20:164-175.
37. Uccelletti, D., F. Farina, S. Rufini, P. Magnelli, C. Abeijon, and C. Palleschi. 2006. The Kluyveromyces lactis -1,6-mannosyltransferase KlOch1p is required for cell-wall organization and proper functioning of the secretory pathway. FEMS Yeast Res. 6:449-457.
38. Yoko-o, T., K. Tsukahara, T. Watanabe, N. Hata-Sugi, K. Yoshimatsu, T. Nagasu, and Y. Jigami. 2001. Schizosaccharomyces pombe och1 encodes -1,6-mannosyltransferase that is involved in outer chain elongation of N-linked oligosaccharides. FEBS Lett. 489:75-80.