A study of adenosine-deaminase genetic polymorphism in rheumatoid arthritis

International Journal of Immunopathology and Pharmacology

Volumn 23, Issue 3, 2010, Pages 791-795

  Sebastiani, G D ^a   Bottini, N ^b   Greco, E ^b   Saccucci, P ^b   Canu, G ^a   Lucarelli, P ^c   Gloria Bottini, F ^b   Fontana, Luigi ^b  

^a SAN CAMILLO FORLANINI HOSPITAL   (Italy)

^b UNIVERSITY OF ROME TOR VERGATA   (Italy)

^c CNR   (Italy)

Author keywords

ADA; Adenosine deaminase; Genetic polymorphism; Rheumatoid arthritis

Indexed keywords

ADENOSINE DEAMINASE; ADENOSINE DEAMINASE1; ADENOSINE DEAMINASE2; ADENOSINE DEAMINASE6; UNCLASSIFIED DRUG;

ADULT; ALLELE; ARTICLE; CODON; CONTROLLED STUDY; DISEASE PREDISPOSITION; FEMALE; GENE LOCUS; GENE MUTATION; GENETIC POLYMORPHISM; GENETIC VARIABILITY; GENOTYPE; HAPLOTYPE; HUMAN; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; RHEUMATOID ARTHRITIS;

EID: 78149269956     PISSN: 03946320     EISSN: None     Source Type: Journal    
DOI: 10.1177/039463201002300313     Document Type: Article

References (12)

1. Sari RA, Taysi S, Yilmaz O, Bakan N. Correlation of serum levels of adenosine deaminase activity and its isoenzymes with disease activity in rheumatoid arthritis. Clin Exp Rheumatol 2003; 21:87-90. (Pubitemid 36267537)
2. Nakamachi Y, Koshiba, M, Nakazawa T, Hatachi S, Saura R, Kurosaka M, Kusaka H Kumagai S. Specific increase in enzymatic activity of adenosine deaminase 1 in rheumatoid synovial fibroblasts. Arthritis Rheumatol 2003; 48:668-74. (Pubitemid 36302002)
3. Ottonello L, Frumento G, Arduino N, Bertolotto M, Mancini M, Sottofattori E, Dallegri F, Cutolo M. Delayed neutrophil apoptosis induced by sinovial fluid in rheumatoid arthritis: role of cytokines, estrogens, and adenosine. Ann NY Acad Sci 2002; 966:226-31. (Pubitemid 34729178)
4. Wessels JA, Kooloos WM, De Jonge R, et al. Relationship between genetic variants in the adenosine pathway and outcome of methotrexate treatment in patients with recent-onset rheumatoid arthritis. Arthritis Rheum 2006; 54:2830-9.
5. Sharma S, Das M, Kumar A, et al. Purine biosynthetic pathway genes and methotrexate response in rheumatoid arthritis patients among north Indians. Pharmacogenet Genomics 2009; 19(10):823-8.
6. Tzall S, Ellenbogen A, Eng F, Hirschhorn R. Identification and characterization of nine RFLPs at the adenosine deaminase (ADA) locus. Am J Hum Genet 1989; 44:864-75. (Pubitemid 19144445)
7. Hirschhorn R, Yang DR, Israni A. An Asp8Asn substitution results in the adenosine deaminase (ADA) genetic polymorphism (ADA 2 allozyme): occurrence on different backgrounds and apparent intragenic crossover. Ann Hum Genet 1994; 58:1-9.
8. Spencer N, Hopkinson D, Harris H. Adenosine deaminase polymorphism in man. Ann Hum Genet 1968; 32:9-14
9. Kunkel LM, Smith KD, Boyer SH, Borgaonkar DS, Wachtel SS, Miller OJ, Breg WR, Jones HW Jr, Rary JM. Analysis of human Y-chromosome - specific reiterated DNA in chromosome variants. Proc Nat Acad Sci USA 1977; 74:1245-9.
10. Whitacre C, Reingold SC, O'Looney A. A gender gap in autoimmunity. Science 1999; 283:1277-78.
11. Franco R, Casado V, Ciruela F, Saura C, Mallo J, Canela EI, Lluis C. Cell surface adenosine deaminase: much more than ectoenzyme. Prog Neurobiol 1997; 52:283-94.
12. Viginton DA, Kaplan DJ, States JC, Akeson AL, Perme CM, Bilyk IJ, Vaughn AJ, Lattier DL, Hutton JJ. Complete sequence and structure of the gene for human adenosine deaminase. Biochem 1986; 25:8234-44.