Anxiety-like behavior in weanling and young adult male and female malnourished rats

Physiology and Behavior

Volumn 102, Issue 1, 2011, Pages 13-16

  Rocinholi, Luciene F ^a,b   Landeira Fernandez, J ^a,b  

^a Universidade Católica   (Brazil)

^b ESTÁCIO DE SÁ UNIVERSITY   (Brazil)

Author keywords

Age; Development; Malnutrition; Sex; T maze

Indexed keywords

ANIMAL EXPERIMENT; ANIMAL MODEL; ANXIETY; ARTICLE; BODY WEIGHT; CONTROLLED STUDY; FEMALE; MALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN CALORIE MALNUTRITION; RAT; WEANING;

AGE FACTORS; ANIMALS; ANIMALS, NEWBORN; ANXIETY; BODY WEIGHT; FEMALE; MALE; MAZE LEARNING; PROTEIN-ENERGY MALNUTRITION; RATS; RATS, WISTAR; SEX CHARACTERISTICS;

EID: 78149255356     PISSN: 00319384     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.physbeh.2010.09.017     Document Type: Article

References (41)

1. Almeida S.S., Tonkiss J., Galler J.R. Prenatal protein malnutrition affects avoidance but not escape behavior in the elevated T-maze. Physiol Behav 1996, 60:191-195.
2. Lukoyanov N.V., Andrade J.P. Behavioral effects of protein deprivation and rehabilitation in adult rats: relevance to morphological alterations in the hippocampal formation. Behav Brain Res 2000, 112:85-97.
3. Morgane P., Austin-LaFrance R.J., Bronzino J., Tonkiss J., Diaz-Cintra S., Cintra L., et al. Prenatal malnutrition and development of the brain. Neurosci Biobehav Rev 1993, 17:91-128.
4. Morgane P., Austin-LaFrance R.J., Bronzino J.D., Tonkiss J., Galler J.R. Malnutrition and the developing central nervous system. The vulnerable brain and environmental risks: malnutrition and hazard assessment 1992, vol. 1:3-44. Plenum Press, New York. R.L. Isaacson, K.F. Jensen (Eds.).
5. Almeida S.S., Soares E.G., Bichuette F.G., Graeff F.G., De Oliveira L.M. Effects of early postnatal malnutrition and chlordiazepoxide on experimental aversive situations. Physiol Behav 1992, 51:1195-1199.
6. Rocinholi L.F., Almeida S.S., De Oliveira L.M. Response threshold to aversive stimuli in stimulated early protein-malnourished rats. Braz J Med Biol Res 1997, 30:407-413.
7. Tonkiss J., Shultz P., Galler J.R. An analysis of spatial navigation in prenatally protein malnourished rats. Physiol Behav 1994, 55:217-224.
8. De Oliveira L.M., Almeida S.S. Effects of malnutrition and environment on the acquisition and extinction of avoidance behavior in rats. Physiol Behav 1985, 34:141-145.
9. Almeida S.S., Garcia R.A., Cibien M.M.R., De Araujo M., Moreira G.M.S., De Oliveira L.M. The ontogeny of exploratory behaviors in early-protein-malnourished rats exposed to the elevated plus-maze test. Psychobiology 1994, 22:283-288.
10. Camargo L.M.M., Almeida S.S. Early postnatal protein malnutrition changes the development of social play in rats. Physiol Behav 2005, 85:246-251.
11. Barros K.M., Manhães-de-Castro R., Lopes-de-Souza S., Matos R.J., Deiró T.C., Cabral-Filho J.E., et al. A regional model (Northeastern Brazil) of induced mal-nutrition delays ontogeny of reflexes and locomotor activity in rats. Nutr Neurosci 2006, 9:99-104.
12. Almeida S.S., De Araújo M. Postnatal protein malnutrition affects play behavior and other social interactions in juvenile rats. Physiol Behav 2001, 74:45-51.
13. Riul T.R., Almeida P.S., Carvalho A.F., Almeida S.S., De Oliveira L.M. Effects of different levels of protein and environmental stimulation on the behavior of young rats tested in the elevated plus-maze. Nutr Neurosci 1998, 1:295-303.
14. Almeida S.S., De Oliveira L.M., Graeff F.G. Early life protein malnutrition changes exploration of the elevated plus-maze and reactivity to anxiolytics. Psychopharmacology (Berl) 1991, 103:513-518.
15. Almeida S.S., Garcia R.A., De Oliveira L.M. Effects of early malnutrition and repeated testing upon locomotor and exploratory behaviors in the elevated plus-maze. Physiol Behav 1993, 54:749-752.
16. Almeida S.S., Tonkiss J., Galler J.R. Prenatal protein malnutrition affects exploratory behavior of female rats in the elevated plus-maze test. Physiol Behav 1996, 60:675-680.
17. Brioni J.D., Orsingher O.A. Operant behavior and reactivity to the anticonflict effect of diazepam in perinatally undernourished rats. Physiol Behav 1988, 44:193-198.
18. Laino C.H., Cordoba N.E., Orsingher O.A. Perinatally protein-deprived rats and reactivity to anxiolytic drugs in the plus-maze test: an animal model for screening antipanic agents. Pharmacol Biochem Behav 1993, 46:89-94.
19. Guide for the care and use of laboratory animals 1996, National Research Council, Washington DC. 7th edition.
20. Hernandes A.S., Françolin-Silva A.L., Valadares C.T., Fukuda M.T.H., Almeida S.S. Effects of different malnutrition techniques on the behavior of rats tested in the elevated T-maze. Behav Brain Res 2005, 162:240-245.
21. Lago E.S., Teodósio N.R., Araújo C.R., Azevedo M.C., Pessoa D.C., Campos F.A., et al. Rat models of protein and protein-energy malnutrition. Int J Vitam Nutr Res 1993, 63:52-56.
22. Lima J.G., De Oliveira L.M., Lachat J.J., Dal-Bo C.M.R., Almeida S.S. Comparison of the effects of lab chow and casein diets based on body and brain development of rats. Braz J Med Biol Res 1993, 26:1069-1076.
23. Schulz D., Huston J.P., Buddenberg T., Topic B. "Despair" induced by extinction trials in the water maze: relationship with measures of anxiety in aged and adult rats. Neurobiol Learn Mem 2007, 87:309-323.
24. Genn R.F., Tucci S.A., Thomas A., Edwards J.E., File S.E. Age-associated sex differences in response to food deprivation in two animal tests of anxiety. Neurosci Biobehav Rev 2003, 27:155-161.
25. Sanson L.T., Corobrez A.P. Long-lasting inhibitory avoidance acquisition in rats submitted to the elevated T-maze model of anxiety. Behav Brain Res 1999, 101:59-64.
26. Imhof J.T., Coelho Z.M.I., Schmitt M.L., Morato G.S., Carobrez A.P. Influence of gender and age on performance of rats in the elevated plus maze apparatus. Behav Brain Res 1993, 56:177-180.
27. Viana M.B., Tomaz C., Graeff F.G. The elevated T-maze: a new animal model of anxiety and memory. Pharmacol Biochem Behav 1994, 49:549-554.
28. Jarrard L.E. On the role of the hippocampus in learning and memory in the rat. Behav Neural Biol 1993, 60:9-26.
29. Goodrich-Hunsaker N.J., Livingstone S.A., Skelton R.W., Hopkins R.O. Spatial deficits in a virtual water maze in amnesic participants with hippocampal damage. Hippocampus 2010, 20:481-491.
30. Coupé B., Dutriez-Casteloot I., Breton C., Lefèvre F., Mairesse J., Dickes-Coopman A., et al. Perinatal undernutrition modifies cell proliferation and brain-derived neurotrophic factor levels during critical time-windows for hypothalamic and hippocampal development in the male rat. J Neuroendocrinol 2009, 21:40-48.
31. Levitsky D.A., Strupp B.J. Malnutrition and the brain: changing concepts, changing concerns. J Nutr 1995, 125:2212S-2220S.
32. Foy M.R., Baudry M., Akopian G.K., Thompson R.F. Regulation of hippocampal synaptic plasticity by estrogen and progesterone. Vitam Horm 2010, 82:219-239.
33. Smith C.C., Vedder L.C., McMahon L.L. Estradiol and the relationship between dendritic spines, NR2B containing NMDA receptors, and the magnitude of long-term potentiation at hippocampal CA3-CA1 synapses. Psychoneuroendocrinology 2009, 34:S130-S142.
34. Barha C.K., Dalton G.L., Galea L.A. Low doses of 17alpha-estradiol and 17beta-estradiol facilitate, whereas higher doses of estrone and 17alpha- and 17beta-estradiol impair, contextual fear conditioning in adult female rats. Neuropsychopharmacology 2010, 35:547-559.
35. Holmes M.M., Wide J.K., Galea L.A. Low levels of estradiol facilitate, whereas high levels of estradiol impair, working memory performance on the radial arm maze. Behav Neurosci 2002, 116:928-934.
36. McElroy M.W., Korol D.L. Intrahippocampal muscimol shifts learning strategy in gonadally intact young adult female rats. Learn Mem 2005, 12:150-158.
37. Lesage J., Blondeau B., Grino M., Breant B., Dupouy J.P. Maternal undernutrition during late gestationinducesfetal overexposure to glucocorticoids and intrauterine growth retardation, and disturbs the hypothalamo-pituitary adrenal axis in the newborn rat. Endocrinology 2001, 142:1672-1702.
38. Vieau D., Sebaai N., Léonhardt M., Dutriez-Casteloot I., Molendi-Coste O., Loborie C., et al. HPA axisprograming by maternal undernutrition in the rat offspring. Psychoneuroendocrinology 2007, 32:S16-S20.
39. Massaro T.F., Levitsky D.A., Barnes R.H. Protein malnutrition in the rat: its effects on maternal behavior and pup development. Dev Psychobiol 1974, 7:551-561.
40. Levitsky D.A., Massaro T.F., Barnes R.H. Maternal malnutrition and the nonatal environment. Fed Proc 1975, 34:1538-1586.
41. Riul T.R., Carvalho A.F., Almeida P.S., De Oliveira L.M., Almeida S.S. Ethological analysis of mother-pup interactions and other behavioral reactions in rats: effects of malnutrition and tactile stimulation of the pups. Braz J Med Biol Res 1999, 32:975-983.