The mechanism of vitexin-4"-O-glucoside protecting ECV-304 cells against tertbutyl hydroperoxide induced injury

Natural Product Research

Volumn 24, Issue 18, 2010, Pages 1695-1703

  Li, Hai Bo ^a   Ying, Xi Xiang ^b   Lu, Jia ^b  

^a LIAONING UNIVERSITY   (China)

^b LIAONING UNIVERSITY OF TRADITIONAL CHINESE MEDICINE   (China)

Author keywords

antioxidation; ECV 304 cell; tertbutyl hydroperoxide; vitexin 4" O glucoside

Indexed keywords

ANTIOXIDANT; GLUCOSIDE; GLUTATHIONE; GLUTATHIONE DISULFIDE; MALONALDEHYDE; SUPEROXIDE DISMUTASE; TERT BUTYL HYDROPEROXIDE; UNCLASSIFIED DRUG; VITEXIN 4'' O GLUCOSIDE;

ANTIOXIDANT ACTIVITY; APOPTOSIS; ARTICLE; CELL DAMAGE; CELL PROTECTION; CELL STRUCTURE; CELL VIABILITY; CYTOTOXICITY; DRUG MECHANISM; ENZYME ACTIVITY; HUMAN; HUMAN CELL; LIPID PEROXIDATION; MITOCHONDRIAL MEMBRANE POTENTIAL;

ANALYSIS OF VARIANCE; CELL LINE; CELL SURVIVAL; CRATAEGUS; DRUGS, CHINESE HERBAL; FLAVONES; GLUCOSIDES; HUMANS; IN SITU NICK-END LABELING; ISOFLAVONES; LIPID PEROXIDATION; MEMBRANE POTENTIAL, MITOCHONDRIAL; MICROSCOPY, PHASE-CONTRAST; MOLECULAR STRUCTURE; PLANT EXTRACTS; PLANT LEAVES; RHODAMINE 123; SUPEROXIDE DISMUTASE; TERT-BUTYLHYDROPEROXIDE; TETRAZOLIUM SALTS; THIAZOLES;

EID: 78149249525     PISSN: 14786419     EISSN: 14786427     Source Type: Journal    
DOI: 10.1080/14786410902853847     Document Type: Article

References (17)

1. Beyer, G., & Melzig, M.F. (2003). Effects of selected flavonoids and caffeic acid derivatives on hypoxanthine-xanthine oxidase-induced toxicity in cultivated human cells. Planta Medica, 69, 1125-1129.
2. Beyer, G., & Melzig, M.F. (2005). Effects of propolis on hypoxanthine-xanthine oxidase-induced toxicity in cultivated human cells and on neutrophil elastase activity. Bioligical and Pharmaceutical Bulletin, 28, 1183-1186.
3. Chauhan, V., & Chauhan, A. (2006). Oxidative stress in Alzheimer's disease. Pathophysiology, 13, 195-208.
4. Cortez-pinto, H., Lin, H.Z., Yang, S.Q., Odwin da costa, S., & Diehl, A.M. (1999). Lipids up-regulate uncoupling protein 2 expression in rat hepatocytes. Gastroenterology, 116, 1184-1198.
5. Daba, M.H., & Abdel-rahman, M.S. (1998). Hepatoprotective activity of thymoquinone in isolated rat hepatocytes. Toxicology Letters, 95, 23-29.
6. Dumont, P., Burton, M., Chen, Q.M., Gonos, E.S., Frippiat, C., Mazarati, J.B., et al. (2000). Induction of replicative senescence biomarkers by sublethal oxidative stresses in normal human fibroblast. Free Radical Biology and Medicine, 28, 361-373.
7. von Harsdorf, R., Li, P.F., & Dietz, R. (1999). Signaling pathways in reactive oxygen species-induced cardiomyocyte apoptosis. Circulation, 99, 2934-2941.
8. Hernandez, S., Lopez-knowles, E., Lloreta, J., Kogevinas, M., Jaramillo, R., Amoros, A., et al. (2005). FGFR3 and Tp53 mutations in T1G3 transitional bladder carcinomas: independent distribution and lack of association with prognosis. Clinical Cancer Research, 11, 5444-5450.
9. Kautiainen, A., Wachtmeister, C.A., & Ehrenberg, L. (1998). Characterization of hemoglobin adducts from a 4, 4'-methylenedianiline metabolite evidently produced by peroxidative oxidation in vivo. Chemical Research in Toxicology, 11, 614-621.
10. Kennedy, C.H., Church, D.F., Winston, G.W., & Pryor, W.A. (1992). Tert-butyl hydroperoxide-induced radical production in rat liver mitochondria. Free Radical Biology and Medicine, 12, 381-387.
11. Kumar, A., Naidu, P.S., Seghal, N., & Padi, S.S. (2007). Neuroprotective effects of resveratrol against intracerebroventricular colchicine-induced cognitive impairment and oxidative stress in rats. Pharmacology, 79, 17-26. (Pubitemid 46034173)
12. Lazze, M.C., Pizzala, R., Savio, M., Stivala, L.A., Prosperi, E., & Bianchi, L. (2003). Anthocyanins protect against DNA damage induced by tert-butyl-hydroperoxide in rat smooth muscle and hepatoma cells. Mutation Research, 535, 103-115.
13. Li, H.B., Yi, X., Gao, J.M., Ying, X.X., Guan, H.Q., & Li, J.C. (2008). The mechanism of hyperoside protection of ECV-304 cells against tert-butyl hydroperoxide-induced injury. Pharmacology, 82, 105-113.
14. Liu, R.H., & Yu, B.Y. (2006). Study on the chemical constituents of the leaves from Crataegus pinnatifida Bge. var. major N. E. Br. Zhong Yao Cai, 29, 1169-1173.
15. Ying, X.X., Li, H.B., Chu, Z.Y., Zhai, Y.J., Leng, A.J., Liu, X., et al. (2008). HPLC determination of malondialdehyde in ECV304 cell culture medium for measuring the antioxidant effect of vitexin-4"-O-glucoside. Archives of Pharmacal Research, 31, 878-885.
16. Zou, C.G., Agar, N.S., & Jone, G.L. (2001). Oxidative insult in sheep red blood cells induced by T-butyl hydroperoxide: the roles of glutathione and glutathione peroxidase. Free Radical Research, 34, 45-56.
17. Zuo, Z., Zhang, L., Zhou, L., Chang, Q., & Chow, M. (2006). Intestinal absorption of hawthorn flavonoids-in vitro, in situ and in vivo correlations. Life Science, 79, 2455-2462.