Thiol-disulfide interchange in the tocinoic acid/glutathione system during freezing and drying

Journal of Pharmaceutical Sciences

Volumn 99, Issue 12, 2010, Pages 4849-4856

  Thing, Mette ^a,b   Zhang, Jun ^c   Laurence, Jennifer ^a   Topp, Elizabeth M ^c  

^a UNIVERSITY OF KANSAS   (United States)

^b UNIVERSITY OF COPENHAGEN   (Denmark)

^c PURDUE UNIVERSITY   (United States)

Author keywords

Freeze drying; Lyophilization; Peptide; Protein aggregation; Solid state; Thiol disulfide interchange

Indexed keywords

AMINO ACID; DISULFIDE; EXCIPIENT; GLUTATHIONE; GLUTATHIONE DISULFIDE; PHOSPHATE BUFFERED SALINE; POLYSORBATE 20; SUCROSE; THIOL; TOCINOIC ACI; UNCLASSIFIED DRUG;

ARTICLE; CONTROLLED STUDY; DEFENSE MECHANISM; DRUG FORMULATION; FREEZE DRYING; OXIDATION REDUCTION POTENTIAL; SPRAY DRYING;

EID: 78049524256     PISSN: 00223549     EISSN: 15206017     Source Type: Journal    
DOI: 10.1002/jps.22206     Document Type: Article

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