Genetic determinants of virulence, antibiogram and altered biotype among the Vibrio cholerae O1 isolates from different cholera outbreaks in India

Infection, Genetics and Evolution

Volumn 10, Issue 6, 2010, Pages 814-818

  Goel, A K ^a,b   Jiang, S C ^b  

^a DEFENCE RESEARCH AND DEVELOPMENT ESTABLISHMENT   (India)

^b University of California at Irvine   (United States)

Author keywords

Antibiotic resistant; Biotype; Cholera; Evolution; Pathogenicity; Toxin; Vibrio cholerae

Indexed keywords

AMPICILLIN; CHLORAMPHENICOL; CHOLERA TOXIN B SUBUNIT; CIPROFLOXACIN; COTRIMOXAZOLE; GENE PRODUCT; GENTAMICIN; KANAMYCIN; NALIDIXIC ACID; NITROFURANTOIN; NORFLOXACIN; POLYMYXIN B; PROTEIN ACE; PROTEIN HLYA; PROTEIN OMPU; PROTEIN OMPW; PROTEIN RFBO1; PROTEIN RTXC; PROTEIN TCP; PROTEIN TOXR; PROTEIN VIZ; PROTEIN ZOT; SPECTINOMYCIN; STREPTOMYCIN; SULFAMETHIZOLE; SULFAMETHOXAZOLE; TETRACYCLINE; TRIMETHOPRIM; UNCLASSIFIED DRUG; UNINDEXED DRUG; VIRULENCE FACTOR; ANTIINFECTIVE AGENT;

ANTIBIOTIC RESISTANCE; ANTIBIOTIC SENSITIVITY; ARTICLE; BACTERIAL STRAIN; BACTERIAL VIRULENCE; BACTERIUM ISOLATE; BIOTYPE; CHOLERA; EPIDEMIC; GENE SEQUENCE; HUMAN; INDIA; INTEGRON; MULTIPLEX POLYMERASE CHAIN REACTION; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; VIBRIO CHOLERAE; AMINO ACID SEQUENCE; ANTIGENIC VARIATION; BACTERIUM IDENTIFICATION; CLASSIFICATION; DRUG EFFECT; GENETICS; ISOLATION AND PURIFICATION; MICROBIOLOGICAL EXAMINATION; MICROBIOLOGY; MOLECULAR GENETICS; SEQUENCE HOMOLOGY; VIRULENCE;

VIBRIO CHOLERAE;

AMINO ACID SEQUENCE; ANTI-BACTERIAL AGENTS; ANTIGENIC VARIATION; BACTERIAL TYPING TECHNIQUES; CHOLERA; DISEASE OUTBREAKS; DRUG RESISTANCE, BACTERIAL; HUMANS; INDIA; MICROBIAL SENSITIVITY TESTS; MOLECULAR SEQUENCE DATA; SEQUENCE HOMOLOGY, AMINO ACID; VIBRIO CHOLERAE O1; VIRULENCE;

EID: 78049523217     PISSN: 15671348     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.meegid.2009.06.022     Document Type: Article

References (38)

1. Beaber J.W., Waldor M.K. Identification of operators and promoters that control SXT conjugative transfer. J. Bacteriol. 2004, 186:5945-5949.
2. Beaber J.W., Hochhut B., Waldor M.K. Genomic and functional analyses of SXT, an integrating antibiotic resistance gene transfer element derived from Vibrio cholerae. J. Bacteriol. 2002, 184:4259-4269.
3. Beaber J.W., Hochhut B., Waldor M.K. SOS response promotes horizontal dissemination of antibiotic resistance genes. Nature 2004, 427:72-74.
4. Chow K.H., Ng T.K., Yuen K.Y., Yam W.C. Detection of RTX toxin gene in Vibrio cholerae by PCR. J. Clin. Microbiol. 2001, 39:2594-2597.
5. CLSI, 2007. Performance standards for antimicrobial susceptibility testing; Seventeenth Informational Supplement: CLSI document M100-S17 (ISBN 1-56238-625-5). Clinical and Laboratory Standard Institute, 940 West Valley Road, Suite 1400, Wayne Pennsylvania 19087-1898, USA.
6. Coote J.G. Structural and functional relationships among the RTX toxin determinants of gram-negative bacteria. FEMS Microbiol. Rev. 1992, 8:137-161.
7. Faruque A.S., Alam K., Malek M.A., Khan M.G., Ahmed S., Saha D., Khan W.A., Nair G.B., Salam M.A., Luby S.P., Sack D.A. Emergence of multidrug-resistant strain of Vibrio cholerae O1 in Bangladesh and reversal of their susceptibility to tetracycline after two years. J. Health Popul. Nutr. 2007, 25:241-243.
8. Faruque S.M., Albert M.J., Mekalanos J.J. Epidemiology, genetics, and ecology of toxigenic Vibrio cholerae. Microbiol. Mol. Biol. Rev. 1998, 62:1301-1314.
9. Faruque S.M., Sack D.A., Sack R.B., Colwell R.R., Takeda Y., Nair G.B. Emergence and evolution of Vibrio cholerae O139. Proc. Natl. Acad. Sci. U.S.A. 2003, 100:1304-1309.
10. Finkelstein, R.A., 2006. Vibrio cholerae O1 and O139, and other pathogenic vibrios. [online]. http://gsbs.utmb.edu/microbook/ch024.htm.
11. Garg P., Sinha S., Chakraborty R., Bhattacharya S.K., Nair G.B., Ramamurthy T., Takeda Y. Emergence of fluoroquinolone-resistant strains of Vibrio cholerae O1 biotype El Tor among hospitalized patients with cholera in Calcutta, India. Antimicrob. Agents Chemother. 2001, 45:1605-1606.
12. Garg P., Chakraborty S., Basu I., Datta S., Rajendran K., Bhattacharya T., Yamasaki S., Bhattacharya S.K., Takeda Y., Nair G.B., Ramamurthy T. Expanding multiple antibiotic resistance among clinical strains of Vibrio cholerae isolated from 1992-7 in Calcutta, India. Epidemiol. Infect. 2000, 124:393-399.
13. Ghosh J., Senoh M., Hamabata T., Mukhapadhayay A.K., Ramamurthy T., Chatterjee S., Asakura M., Yamasaki S., Nair G.B., Takeda Y. New variants of Vibrio cholerae O1 El Tor produce higher levels of cholera toxin as compared to prototype El Tor strains. 13th International Conference on Emerging Infectious Diseases in the Pacific Rim conducted by US-Japan Cooperative Medical Science Program from April 6-9 2009, 54.
14. Goel A.K., Jain M., Kumar P., Bhadauria S., Kmboj D.V., Singh L. A new variant of Vibrio cholerae O1 El Tor causing cholera in India. J. Infect. 2008, 57:280-281.
15. Hall R.M., Collis C.M. Mobile gene cassettes and integrons: capture and spread of genes by site-specific recombination. Mol. Microbiol. 1995, 15:593-600.
16. Hochhut B., Lotfi Y., Mazel D., Faruque S.M., Woodgate R., Waldor M.K. Molecular analysis of antibiotic resistance gene clusters in Vibrio cholerae O139 and O1 SXT constins. Antimicrob. Agents Chemother. 2001, 45:2991-3000.
17. Huq A., Parveen S., Qadri F., Sack D.A., Colwell R.R. Comparison of Vibrio cholerae serotype O1 strains isolated from patients and the aquatic environment. J. Trop. Med. Hyg. 1993, 96:86-92.
18. Iwanaga M., Toma C., Miyazato T., Insisiengmay S., Nakasone N., Ehara M. Antibiotic resistance conferred by a class I integron and SXT constin in Vibrio cholerae O1 strains isolated in Laos. Antimicrob. Agents Chemother. 2004, 48:2364-2369.
19. Jesudason M.V. Change in serotype and appearance of tetracycline resistance in V. cholerae O1 in Vellore, South India. Indian J. Med. Microbiol. 2006, 24:152-153.
20. Kaper J.B., Morris J.G., Levine M.M. Cholera. Clin. Microbiol. Rev. 1995, 8:48-86.
21. Krishna B.V., Patil A.B., Chandrasekhar M.R. Fluoroquinolone-resistant Vibrio cholerae isolated during a cholera outbreak in India. Trans. R. Soc. Trop. Med. Hyg. 2006, 100:224-226.
22. Kumar P., Jain M., Goel A.K., Bhadauria S., Sharma S.K., Kamboj D.V., Singh L., Ramamurthy T., Nair G.B. A large cholera outbreak due to a new cholera toxin variant of the Vibrio cholerae O1 El Tor biotype in Orissa, Eastern India. J. Med. Microbiol. 2009, 58:234-238.
23. Lee K. The global dimensions of cholera. Global Change Hum. Health 2001, 2:6-17.
24. Morita M., Ohnishi M., Arakawa E., Bhuiyan N.A., Nusrin S., Alam M., Siddique A.K., Qadri F., Izumiya H., Nair G.B., Watanabe H. Development and validation of a mismatch amplification mutation PCR assay to monitor the dissemination of an emerging variant of Vibrio cholerae O1 biotype El Tor. Microbiol. Immunol. 2008, 52:314-317.
25. Mukhopadhyay A.K., Basu I., Bhattacharya S.K., Bhattacharya M.K., Nair G.B. Emergence of fluoroquinolone resistance in strains of Vibrio cholerae isolated from hospitalized patients with acute diarrhea in Calcutta, India. Antimicrob. Agents Chemother. 1998, 42:206-207.
26. Nair G.B., Faruque S.M., Bhuiyan N.A., Kamruzzaman M., Siddique A.K., Sack D.A. New variants of Vibrio cholerae O1 biotype El Tor with attributes of the classical biotype from hospitalized patients with acute diarrhea in Bangladesh. J. Clin. Microbiol. 2002, 40:3296-3299.
27. Nair G.B., Qadri F., Holmgren J., Svennerholm A.M., Safa A., Bhuiyan N.A., Ahmad Q.S., Faruque S.M., Faruque A.S., Takeda Y., Sack D.A. Cholera due to altered El Tor strains of Vibrio cholerae O1 in Bangladesh. J. Clin. Microbiol. 2006, 44:4211-4213.
28. Nandi B., Nandy R.K., Mukhopadhyay S., Nair G.B., Shimada T., Ghose A.C. Rapid method for species-specific identification of Vibrio cholerae using primers targeted to the gene of outer membrane protein OmpW. J. Clin. Microbiol. 2000, 38:4145-4151.
29. Nguyen B.M., Lee J.H., Cuong N.T., Choi S.Y., Hien N.T., Anh D.D., Lee H.R., Ansaruzzaman M., Endtz H.P., Chun J., Lopez A.L., Czerkinsky C., Clemens J.D., Kim D.W. Cholera outbreaks caused by an altered Vibrio cholerae O1 El Tor biotype strain producing classical cholera toxin B in Vietnam in 2007 to 2008. J. Clin. Microbiol. 2009, 47:1568-1571.
30. Olsvik O., Wahlberg J., Petterson B., Uhlen M., Popovic T., Wachsmuth I.K., Fields P.I. Use of automated sequencing of polymerase chain reaction-generated amplicons to identify three types of cholera toxin subunit B in Vibrio cholerae O1 strains. J. Clin. Microbiol. 1993, 31:22-25.
31. Popovic T., Fields P.I., Olsvik O. Detection of cholera toxin genes. Vibrio cholerae and Cholera: Molecular to Global Perspectives 1994, 41-52. American Society for Microbiology, Washington. I.K. Wachsmuth, P.A. Blake, O. Olsvik (Eds.).
32. Recchia G.D., Hall R.M. Plasmid evolution by acquisition of mobile gene cassettes: plasmid pIE723 contains the aadB gene cassette precisely inserted at a secondary site in the incQ plasmid RSF1010. Mol. Microbiol. 1995, 15:179-187.
33. Sabeena F., Thirivikramji G., Radhakutty G., Indu P., Singh D.V. In vitro susceptibility of Vibrio cholerae O1 biotype El Tor strains associated with an outbreak of cholera in Kerala, Southern India. J. Antimicrob. Chemother. 2001, 47:361-362.
34. Sack D.A., Sack R.B., Nair G.B., Siddique A.K. Cholera. Lancet 2004, 363:223-233.
35. Shaw K.J., Rather P.N., Hare R.S., Miller G.H. Molecular genetics of aminoglycoside resistance genes and familial relationships of the aminoglycoside-modifying enzymes. Microbiol. Rev. 1993, 57:138-163.
36. Tamrakar A.K., Goel A.K., Kamboj D.V., Singh L. Surveillance methodology for Vibrio cholerae in environmental samples. Int. J. Environ. Health Res. 2006, 16:305-312.
37. Waldor M.K., Mekalanos J.J. Lysogenic conversion by a filamentous phage encoding cholera toxin. Science 1996, 272:1910-1914.
38. WHO Cholera, 2007. Wkly. Epidemiol. Rec. 2008, 83:269-283.