Involvement of sarcoplasmic reticulum in changing intracellular calcium due to NA+/K+-ATPase inhibition in cardiomyocytes

Canadian Journal of Physiology and Pharmacology

Volumn 88, Issue 7, 2010, Pages 702-715

  Saini Chohan, Harjot K ^a   Goyal, Ramesh K ^a,b   Dhalla, Naranjan S ^a  

^a UNIVERSITY OF MANITOBA   (Canada)

^b M S UNIVERSITY OF BARODA   (India)

Author keywords

Ca2+ handling in cardiomyocytes; Ca2+ induced Ca2+ release; Cardiac glycosides; Cardiac Na+ K+ pump; SL Ca2+ channels; SL Na+ Ca2+ exchange; SR Ca2+ transport

Indexed keywords

2 [2 [4 (4 NITROBENZYLOXY)PHENYL]ETHYL]ISOTHIOUREA METHANESULFONATE; ADENOSINE TRIPHOSPHATASE (POTASSIUM SODIUM); CAFFEINE; CALCIUM; CYCLOPIAZONIC ACID; FURA 2; KT 5720; N [2 (4 BROMOCINNAMYLAMINO)ETHYL] 5 ISOQUINOLINESULFONAMIDE; OUABAIN; RYANODINE; VERAPAMIL; ADENOSINE TRIPHOSPHATE; CALCIUM CALMODULIN DEPENDENT PROTEIN KINASE; CYCLIC AMP DEPENDENT PROTEIN KINASE; INOSITOL 1,4,5 TRISPHOSPHATE RECEPTOR; POTASSIUM CHLORIDE;

ANIMAL CELL; ARTICLE; CALCIUM CELL LEVEL; CALCIUM TRANSPORT; CELL ISOLATION; DRUG EFFECT; DRUG MECHANISM; ENZYME INHIBITION; HEART MUSCLE CELL; NONHUMAN; PRIORITY JOURNAL; RAT; SARCOPLASMIC RETICULUM; ANIMAL; CALCIUM SIGNALING; DRUG ANTAGONISM; HEART MITOCHONDRION; IN VITRO STUDY; MALE; METABOLISM; SARCOLEMMA; SPRAGUE DAWLEY RAT;

ADENOSINE TRIPHOSPHATE; ANIMALS; CAFFEINE; CALCIUM; CALCIUM SIGNALING; CALCIUM-CALMODULIN-DEPENDENT PROTEIN KINASES; CYCLIC AMP-DEPENDENT PROTEIN KINASES; INOSITOL 1,4,5-TRISPHOSPHATE RECEPTORS; MALE; MITOCHONDRIA, HEART; MYOCYTES, CARDIAC; OUABAIN; POTASSIUM CHLORIDE; RATS; RATS, SPRAGUE-DAWLEY; RYANODINE; SARCOLEMMA; SARCOPLASMIC RETICULUM; SODIUM-POTASSIUM-EXCHANGING ATPASE;

EID: 78049519105     PISSN: 00084212     EISSN: 12057541     Source Type: Journal    
DOI: 10.1139/Y10-055     Document Type: Article

References (44)

1. 2+ under various conditions. J. Mol. Cell. Cardiol. 24(7): 765-773. doi:10.1016/0022-2828(92)93390-6. PMID:1383555.
2. 2+ exchanger function. J. Physiol. 575(3): 845-854. doi:10.1113/jphysiol.2006. 111252. PMID:16825310.
3. Bare, D.J., Kettlun, C.S., Liang, M., Bers, D.M., and Mignery, G.A. 2005. Cardiac type 2 inositol 1,4,5-trisphosphate receptor: interaction and modulation by calcium/calmodulin-dependent protein kinase II. J. Biol. Chem. 280(16): 15912-15920. doi:10. 1074/jbc.M414212200. PMID:15710625.
4. 2+ transients in the human heart. J. Appl. Physiol. 83(2): 652-660.PMID:9262464.
5. Crompton, M., Kunzi, M., and Carafoli, E. 1997. The calciuminduced and sodium-induced effluxes of calcium from heart mitochondria. Evidence for a sodium-calcium carrier. Eur. J. Biochem. 79(2): 549-558. doi:10.1111/j.1432-1033.1977.tb11839.x.
6. Dhalla, N.S., and Wang, J. 1999. Role of protein kinase C and protein kinase A in heart functions in health and disease. Exp. Clin. Cardiol. 4: 7-19.
7. 2+-handling in normal and failing hearts. Exp. Clin. Cardiol. 1: 7-20.
8. Dhalla, N.S., Saini-Chohan, H.K., Rodriguez-Leyva, D., Elimban, V., Dent, M.R., and Tappia, P.S. 2009. Subcellular remodelling may induce cardiac dysfunction in congestive heart failure. Car diovasc. Res. 81(3): 429-438. doi:10.1093/cvr/cvn281. PMID:18852252.
9. Dutta, S., Goswami, S., Datta, D.K., Lindower, J.O., and Marks, B.H. 1968. The uptake and binding of six radiolabeled cardiac glycosides by guinea-pig hearts and by isolated sarcoplasmic reticulum. J. Pharmacol. Exp. Ther. 164(1): 10-21.PMID:4235402.
10. Fozzard, H.A., and Sheets, M.F. 1985. Cellular mechanism of action of cardiac glycosides. J. Am. Coll. Cardiol. 5(5 Suppl. A): 10A-15A.PMID:2580874.
11. Fujino, S., and Fujino, M. 1982. Ouabain potentiation and Ca release from sarcoplasmic reticulum in cardiac and skeletal muscle cells. Can. J. Physiol. Pharmacol. 60(4): 542-555.PMID:6286075.
12. Isenberg, G. 1984. Contractility of isolated bovine ventricular myocytes is enhanced by intracellular injection of cardioactive glycosides. Evidence for an intracellular mode of action. Basic Res. Cardiol. 79(Suppl.): 56-71.PMID:6743198.
13. Kennedy, D.J., Vetteth, S., Xie, M., Periyasamy, S.M., Xie, Z., Han, C., et al. 2006. Ouabain decreases sarco(endo)plasmic reticulum calcium ATPase activity in rat hearts by a process involving protein oxidation. Am. J. Physiol. Heart Circ. Physiol. 291(6): H3003-H3011. doi:10.1152/ajpheart.00603.2006. PMID:16861692.
14. Kockskämper, J., Zima, A.V., Roderick, H.L., Pieske, B., Blatter, L.A., and Bootman, M.D. 2008. Emerging roles of inositol 1,4,5-trisphosphate signaling in cardiac myocytes. J. Mol. Cell. Cardiol. 45(2): 128-147. doi:10.1016/j.yjmcc.2008.05.014.PMID:18603259.
15. Langer, G.A., and Serena, S.D. 1970. Effects of strophanthidin upon contraction and ionic exchange in rabbit ventricular myocardium: relation to control of active state. J. Mol. Cell. Cardiol. 1(1): 65-90. doi:10.1016/0022-2828(70)90029-5. PMID:4106468.
16. Leblanc, N., and Hume, J.R. 1990. Sodium current-induced release of calcium from cardiac sarcoplasmic reticulum. Science (Washington, D.C.), 248(4953): 372-376.doi:10.1126/science.2158146. PMID:2158146.
17. Levi, A.J. 1991. The effect of strophanthidin on action potential, calcium current and contraction in isolated guinea-pig ventricular myocytes. J. Physiol. 443: 1-23.PMID:1822522.
18. Lipp, P., and Niggli, E. 1994. Sodium current-induced calcium signals in isolated guineapig ventricular myocytes. J. Physiol. 474(3): 439-446.PMID:8014905.
19. + channels with binding sites of high and low affinity for tetrodotoxin in different excitable and non-excitable cells. Eur. J. Biochem. 124(1): 199-203. doi:10.1111/j.1432-1033.1982.tb05925. x. PMID:6282588.
20. Makazan, Z., Saini, H.K., and Dhalla, N.S. 2007. Role of oxidative stress in alterations of mitochondrial function in ischemicreperfused hearts. Am. J. Physiol. Heart Circ. Physiol. 292(4): H1986-H1994. doi:10.1152/ajpheart.01214.2006. PMID:17172267.
21. McDonough, A.A., Velotta, J.B., Schwinger, R.H., Philipson, K.D., and Farley, R.A. 2002. The cardiac sodium pump: structure and function. Basic Res. Cardiol. 97(7 Suppl. 1): I19-I24. doi:10. 1007/s003950200024. PMID:12479229.
22. Miyakawa-Naito, A., Uhlén, P., Lal, M., Aizman, O., Mikoshiba, K., Brismar, H., et al. 2003. Cell signaling microdomain with Na/K-ATPase and inositol 1,4,5-trisphosphate receptor generates calcium oscillations. J. Biol. Chem. 278(50): 50355-50361.doi:10.1074/jbc.M305378200. PMID:12947118.
23. Moschella, M.C., and Marks, A.R. 1993. Inositol 1,4,5-trisphosphate receptor expression in cardiac myocytes. J. Cell Biol. 120(5): 1137-1146. doi:10.1083/jcb.120.5.1137. PMID:8382205.
24. 2+/calmodulin-dependent protein kinase is altered in heart failure. Circ.Res. 86(5): 596-605.PMID:10720422.
25. Nishio, M., Ruch, S.W., and Wasserstrom, J.A. 2002. Positive inotropic effects of ouabain in isolated cat ventricular myocytes in sodium-free conditions. Am. J. Physiol. Heart Circ. Physiol. 283(5): H2045-H2053.PMID:12384484.
26. Nishio, M., Ruch, S.W., Kelly, J.E., Aistrup, G.L., Sheehan, K., and Wasserstrom, J.A. 2004. Ouabain increases sarcoplasmic reticulum calcium release in cardiac myocytes. J. Pharmacol. Exp. Ther. 308(3): 1181-1190. doi:10.1124/jpet.103.060004. PMID: 14634043.
27. +-induced increase in intracellular calcium in KCl-depolarized rat cardiomyocytes, Cell.Biochem. 263(1-2):151-162. doi:10.1023/B:MCBI.0000041857.86178.f6. PMID:15524176.
28. 2+ exchanger is essential for the action of cardiac glycosides. Circ. Res. 90(3): 305-308. doi:10.1161/hh0302.104562. PMID:11861419.
29. Sagawa, T., Sagawa, K., Kelly, J.E., Tsushima, R.G., and Wasserstrom, J.A. 2002. Activation of cardiac ryanodine receptors by cardiac glycosides. Am. J. Physiol. Heart Circ. Physiol. 282(3): H1118-H1126.PMID:11834511.
30. Saini, H.K., and Dhalla, N.S. 2005. Defective calcium handling in cardiomyocytes isolated from hearts subjected to ischemia-reperfusion. Am.J.Physiol. Heart Circ.Physiol. 288(5):H2260-H2270. doi:10.1152/ajpheart.01153.2004. PMID:15653754.
31. + exchanger. Am. J. Physiol. Heart Circ. Physiol. 291(6): H2790-H2800. doi:10.1152/ajpheart.00535.2006. PMID: 16861694.
32. +-ATPase. Am. J. Physiol. Heart Circ. Physiol. 293(1): H169-H181. doi:10.1152/ajpheart. 00007.2007. PMID:17322410.
33. Saini, H.K., Elimban, V., and Dhalla, N.S. 2005. Attenuation of extracellular ATP response in cardiomyocytes isolated from hearts subjected to ischemia-reperfusion. Am. J. Physiol. Heart Circ. Physiol. 289(2): H614-H623. doi:10.1152/ajpheart.00101.2005. PMID:15821038.
34. 2+ exchanger in catecholamine-induced increase in intracellular calcium in cardiomyocytes. Am. J. Physiol. Heart Circ. Physiol. 290(1): H373-H380. doi:10.1152/ajpheart.00613.2005. PMID:16155102.
35. + exchange inhibitor methyl-N-isobutyl amiloride (MIA) on the heart: lack of beneficial effects in ischemia-reperfusion injury. Can. J. Physiol. Pharmacol. 85(1): 67-78. doi:10.1139/Y06-099. PMID:17487246.
36. + channels: slip-mode conductance. Science (Washington, D.C.), 279(5353): 1027-1033.
37. 2+ to ouabain in carotid body glomus cells of adult rabbits. Brain Res.828(1-2): 193-196. doi:10.1016/S0006-8993(99)01359-1. PMID:10320743.
38. 2+ overload in rat ventricular myocytes. Circulation,101(12): 1441-1446.PMID:10736290.
39. Schoner, W., and Scheiner-Bobis, G. 2007. Endogenous and exogenous cardiac glycosides: their roles in hypertension, salt metabolism, and cell growth. Am. J. Physiol. Cell Physiol. 293(2): C509-C536. doi:10.1152/ajpcell.00098.2007. PMID:17494630.
40. 2+ transport and gene expression in congestive heart failure are modified by imidapril treatment. Am. J. Physiol. Heart Circ. Physiol. 288(4):H1674-H1682. doi:10.1152/ajpheart.00945.2004. PMID:15576437.
41. 2+ transients in an isolated myocyte: effects of strophanthidin. Biochem.Biophys.Res.Commun. 203(2): 1050-1056. doi:10.1006/bbrc.1994.2288. PMID:8093022.
42. 2+]i in rat cardiac myocytes. Am. J. Physiol. Heart Circ. Physiol. 281(5): H1899-H1907PMID:11668049.
43. Wasserstrom, J.A., and Aistrup, G.L. 2005. Digitalis: new actions for an old drug. Am. J. Physiol. Heart Circ. Physiol. 289(5): H1781-H1793. doi:10.1152/ajpheart.00707.2004. PMID:16219807.
44. +-ATPase as a signal transducer. Eur. J. Biochem. 269(10): 2434-2439.doi:10.1046/j.1432-1033.2002.02910.x.PMID:12027880.