Characterization of fertility related antisperm antibodies-a step towards causal treatment of immunological infertility and immuno-contraception

Asian Journal of Andrology

Volumn 12, Issue 6, 2010, Pages 793-794

  Haidl, Gerhard ^a  

^a UNIVERSITY OF BONN   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

AUTOANTIGEN; SPERM ANTIBODY; SPERM ANTIGEN;

ANTIGEN ANTIBODY REACTION; BLOOD TESTIS BARRIER; CRYPTORCHISM; DELAYED IMPLANTATION; EMBRYO DEVELOPMENT; FERTILIZATION IN VITRO; HUMAN; IMMUNOCONTRACEPTION; INTRACYTOPLASMIC SPERM INJECTION; MALE INFERTILITY; NONHUMAN; NOTE; SPERMATOZOON MOTILITY; TESTIS INJURY; VARICOCELE;

ANIMALS; AUTOANTIBODIES; AUTOANTIGENS; CONTRACEPTION; CONTRACEPTION, IMMUNOLOGIC; FEMALE; HUMANS; INFERTILITY; MALE; MICE; NUCLEAR PROTEINS; SPERM-OVUM INTERACTIONS; SPERMATOZOA;

EID: 78049500474     PISSN: 1008682X     EISSN: 17457262     Source Type: Journal    
DOI: 10.1038/aja.2010.112     Document Type: Note

References (12)

1. Wang M, Shi JL, Cheng GY, Hu YQ, Xu C. The antibody against a nuclear autoantigenic sperm protein can result in reproductive failure. Asian J Androl 2009;11:183-92.
2. Fijak M, Meinhardt A. The testis in immune privilege. Immunological Reviews 2006;213:66-81.
3. Hedger MP, Hales DB. Immunophysiology of the male reproductive tract. In: Knobil's and Neill's Physiology of Reproduction, Vol. 1, JD Neill, editor. Amsterdam: Elsevier Inc., 2006, pp1195-286.
4. Bohring C, Krause W. The role of antisperm antibodies during fertilization and for immunological infertility: In: Immunology of gametes and embryo implantation. Chem Immunol Allergy, Vol. 88, UR Markert, editor. Basel: Karger, 2005, pp15-26.
5. Koide SS, Wang L, Kamada M. Antisperm antibodies associated with infertility: properties and encoding genes of target antigens. Proc Soc Exp Biol Med 2000;224:123-32.
6. Munuce MJ, Berta CL, Pauluzzi F, Caille AM. Relationship between antisperm antibodies, sperm movement, and semen quality. Urol Int 2000;65:200-3.
7. Bronson R. Antisperm antibodies: A critical evaluation and clinical guidelines. J Reprod Immunol 1999;45:159-83.
8. Bohring C, Skrzypek J, Krause W. Infuence of antisperm antibodies on the acrosome reaction as determined by fow cytometry. Fertil Steril 2001;76:275-80.
9. Naz RK, Zhu X, Kadam AL. Identification of human sperm peptide sequence involved in egg binding for immunocontraception. Biol Reprod 2000;62:318-24.
10. Focarelli R, Giuffrida A, Capparelli S, Scibona M, Menchini Fabris F, et al. Specific localization in the equatorial region of gp20, a 20 kDa sialyl-glycoprotein of the capacitated human spermatozoon acquired during epididymal transit which is necessary to penetrate zona-free hamster eggs. Mol Hum Reprod 1998;4:119-25.
11. Batova IN, Richardson AT, Widgren EE, O'Rand MG. Analysis of the autoimmune epitopes on human teticular NASP using recombinant and synthetic peptides. Clin Exp Immunol 2000;121:201-9.
12. Lee YH, O'Rand MG. Ultra structural localization of a nuclear autoantigenic sperm protein in spermatogenic cells and spermatozoa. Anat Rec 1993;236:442-8.