Epidemiological study of mountain sickness complicated with multiple organ dysfunction syndrome on the Qinghai-Tibetan Plateau: Report of 103 cases

Scientific Research and Essays

Volumn 5, Issue 17, 2010, Pages 2506-2516

  Zhou, Qiquan ^a   Luo, Yongjun ^a   Li, Hong ^a   Li, Suzhi ^b   Zhang, Xizhou ^c   Gao, Wei ^d   Zheng, Bihai ^b   Yang, Dingzhou ^b   Liu, Fuyu ^a   Gao, Yuqi ^a  

^a THIRD MILITARY MEDICAL UNIVERSITY   (China)

^b General Hospital of Tibet Military Command   (China)

^c The 18th Hospital of PLA   (China)

^d LANZHOU GENERAL HOSPITAL   (China)

Author keywords

High altitude cerebral edema; High altitude pulmonary edema; High altitude multiple organ dysfunction syndrome; Multiple organ dysfunction syndrome; Severe acute mountain sickness

Indexed keywords

EID: 78049493994     PISSN: None     EISSN: 19922248     Source Type: Journal    
DOI: None     Document Type: Article

References (29)

1. Bailey DM, Kleger GR, Holzgraefe M, Ballmer PE, Bärtsch P (2004). Pathophysiological significance of peroxidative stress, neuronal damage, and membrane permeability in acute mountain sickness. J. Appl. Physiol., 96: 1459-1463.
2. Basnyat B, Subedi D, Sleggs J (2000). Disoriented and ataxic pilgrims: an epidemiological study of acute mountain sickness and highaltitude cerebral edema at a sacred lake at 4300 m in the Nepal Himalayas. Wilderness Environ. Med., 11: 89-93.
3. Cui JH, Zhang XZ, Guo YC, He FW, Xie YZ (2000). Changes in Ddimer and fibronectin in plasma in patients with HAPE. Chin. J. Crit. Care Med., 20: 596.
4. Cui JH, Zhang XZ, Xie YZ, Zhou XM, Ha ZD (2001). The changes of coagulation and fibrinolysis function on hypoxia adaptation mechanism. Chin. J. Appl., Physiol. 17: 363-365.
5. Cui JH, Zhang XZ, Ma Y, Zhu YA, Ha ZD, Zhang SP (2001). Changes in blood coagulation and fibrinolysis system in patients with HAPE. Chin. J. Crit. Care Med., 21: 479-480.
6. Diebel LN, Liberati DM, Taub JS (2005). Intestinal epithelial cells modulate PMN activation and apoptosis following bacterial and hypoxic challenges. J. Trauma, 58:1126-1133.
7. Droma Y, Hayano T, Takabayashi Y (1996).Endothelin-1 and interleukin-8 in high altitude pulmonary oedema. Eu. Respiration J., 9: 1947-1949.
8. Gao W, Zhang SF, Zhang DH (2004). Diagnostic criteria of MODS complicated from acute mountain sickness. Med. J. NDFNC., 25: 7-9.
9. Grissom CK, Richer LD, Elstad MR (2005). The effects of a 5-lipoxygenase inhibitor on acute mountain sickness and urinary leukotriene e4 after ascent to high altitude. Chest. 127: 565-570.
10. Hartmann G, Tschöp M, Fischer R (2000). High altitude increases circulating interleukin-6, interleukin-1 receptor antagonist and Creactive protein. Cytokine, 12: 246-252.
11. Hirano T, Hirasawa H, Oda S (2004). Modulation of polymorphonuclear leukocyte apoptosis in the critically ill by removal of cytokines with continuous hemodiafiltration. Blood Purif., 22(2):188-97.
12. Hultgren Radiography Chest X-Ray Score. http://www.docstoc.com/docs/23448840/HAPE-Symptom-Score. HAPE Severity Score.
13. Khan DA, Hashim R, Mirza TM, Rahman MM (2003). Differentiation of pulmonary embolism from high altitude pulmonary edema. J Coll Physicians Surg. Pak., 13: 267-270.
14. Miki K, Unno N, Nagata T (2004). Butyrate suppresses hypoxiainducible factor-1 activity in intestinal epithelial cells under hypoxic conditions. Shock, 22: 446-52.
15. Luo JA, Xu GL (1963). Initial therapeutic effect of blocking high altitude pulmonary edema via the neck. Chin. J. Int. Med., 1: 60-63.
16. Qian LZ (1963). Clinical analyses of 58 cases of high altitude pulmonary edema. Chin. J. Int. Med., 1: 902-904.
17. Ren YS, Cui F, Fu ZM, Lei YQ, Jiang P, Ouzhu LB (2004). Detection and analysis of blood coagulation and fibrinolysis system in patients with HAPE. Chin. J. Pract. Intern. Med., 24: 303-304.
18. Shao YM, Zhang LQ, Deng LH, Yao HG (2005). Clinical study on effects of ulinastatin on patients with systemic inflammatory response syndrome. Chin. Crit Care Med., 17: 228-30.
19. Wu TY, Ding SQ, Liu JL (2007). Who should not go high: chronic disease and work at altitude during construction of the Qinghai-Tibet railroad. High Alt. Med. Biol., 8: 88-107.
20. Yang DZ, Zhou QQ, Li SZ (2009). gastrointestinal dysfunction in acute severe mountain sickness and its relation with multiple organ dysfunction syndrome. Chin. J Crit. Care Med., 21: 95-98.
21. Ren YS, Fu ZG, Shen WM (2010).Incidence of High Altitude Illnesses among Unacclimatized Persons Who Acutely Ascended to Tibet. High Alt. Med. Biol., 11: 39-42.
22. Zhang DM, Zhou QQ, Yang JY (2001). A Clinical Analysis of 306 Cases Acute High Altitude Pulmonary Edema Treated on the Spot in High Altitude Regions. West China Med. J., 16: 208-209.
23. Zhang GY, Deng XM (2005). The role of neutrophilic granulocyte/neutrophilic leukocyte in the nosogenesis/pathogenesis/pathogenesy of acute respiratory distress syndrome (ADRS). Chin. J. Crit. Care Med., 25: 830-833.
24. Zhang SF, Lin SX, Gao W (2001). Report of the consensus conference on diagnostic criteria of ALI/ARDS at high altitudes in Western China. Intensive Care Med., 27: 1539-1546.
25. Zhang SF, Zhang DH, Liu HP (2005). Criteria suitable for diagnosis of acute respiratory distress syndrome/multiple organ dysfunction syndrome at moderately high altitude area. Chin. Crit. Care Med., 17: 217-222.
26. Zhang SF, Zhang DH, Zhang C (2007). Reevaluation of diagnostic criteria of ARDS/MODS at high altitude. Int. Rev. Armed Forces Med. Services, 80: 31-37.
27. Zhou QQ, Liu FY, Zheng BH (2007). The clinical significance of leucocytosis and increase in interleukin content in acute mountain sickness complicated with multiple organ dysfunction syndrome. Chin. Crit. Care Med., 19: 588-592.
28. Zhou QQ, Yang JY, Gao YQ (2006). Analyses of the results of on-thespot treatment for 72 cases of high altitude cerebral adema at high altitudes. Chin. Crit. Care Med., 18: 311-314.
29. Ziaee V, Yunesian M, Ahmadinejad Z (2003). Acute mountain sickness in Iranian trekkers around Mount Damavand (5671 m) in Iran. Wilderness Environ. Med., 14: 214-219.