A metabolic murder mystery: A case-based experiment for the undergraduate biochemistry laboratory

Journal of Chemical Education

Volumn 87, Issue 10, 2010, Pages 1110-1112

  Childs Disney, Jessica L ^a   Kauffmann, Andrew D ^a   Poplawski, Shane G ^a   Lysiak, Daniel R ^a   Stewart, Robert J ^a   Arcadi, Jane K ^a   Dinan, Frank J ^a  

^a CANISIUS COLLEGE   (United States)

Author keywords

Bioanalytical chemistry; Biochemistry; Biotechnology; Electrophoresis; Enzymes; Hands on learning manipulatives; Inquiry based discovery learning; Laboratory instruction; Metabolism; Molecular biology; Problem solving decision making; Upper division undergraduate

Indexed keywords

EID: 78049471480     PISSN: 00219584     EISSN: None     Source Type: Journal    
DOI: 10.1021/ed100243x     Document Type: Article

References (16)

1. National Center for Case Study Teaching in Science. http://ublib. buffalo.edu/libraries/projects/cases/case.html (accessed Jul 2010).
2. Start With A Story; Herreid, C. F., Ed.; NSTA Press: Arlington, VA, 2007.
3. Dinan, F. J.; Szczepankiewicz, S. H.; Carnahan, M.; Colvin, M. T. J. Chem. Educ. 2007, 84, 617-618.
4. Hoffman, M. Science 1991, 254, 931.
5. Deodato, F.; Boenzi, S.; Santorelli, F. M.; Dionisi-Vici, C. Am. J. Med. Genet., Part C 2006, 142C, 104-112.
6. Mullis, K. B.; Faloona, F. A. Methods Enzymol. 1987, 155, 335-350.
7. PCR Primer: A Laboratory Manual; Dieffenbach, C. D., Dveksler, G. S., Eds.; Cold Spring Harbor Laboratory Press: Cold Spring Harbor, NY, 2003.
8. Acquaviva, C.; Benoist, J. F.; Pereira, S.; Callebaut, I.; Koskas, T.; Porquet, D.; Elion, J. Hum. Mutat. 2005, 25, 167-176.
9. Aaij, C.; Borst, P. Biochim. Biophys. Acta 1972, 269, 192-200.
10. Brody, J. R.; Kern, S. E. Anal. Biochem. 2004, 333, 1-13.
11. Sambrook, J.; Russell, D. Molecular Biology: A Laboratory Manual, 3rd ed.; Cold Spring Harbor Laboratory Press: Cold Spring Harbor, NY, 2001.
12. Current Protocols in Molecular Biology; Ausubel, F. M., Brent, R., Kingston, R. E., Moore, D. A., Seidman, J. G., Smith, J. A., Struhl, K., Eds.; John Wiley and Sons, Inc.: New york, 2007.
13. Weller, D. L. J. Chem. Educ. 1994, 71, 340-341.
14. Taylor, A.; Sajan, S. J. Chem. Educ. 2005, 82, 597-598.
15. Jackson, D. D.; Abbey, C. S.; Nugent, D. J. Chem. Educ. 2006, 83, 774-776.
16. Grody, W. W.; Kronquist, K. E.; Lee, E. U.; Edmond, J.; Rome, L. H. Am. J. Hum. Genet. 1993, 53, 1352-1355.