Renin-angiotensin system blockade safely reduces blood pressure in patients with minor ischemic stroke during the acute phase

Journal of Stroke and Cerebrovascular Diseases

Volumn 19, Issue 6, 2010, Pages 435-440

  Nakamura, Tomomi ^a,b   Tsutsumi, Yukiko ^a   Shimizu, Yuko ^a   Uchiyama, Shinichiro ^a  

^a TOKYO WOMEN'S MEDICAL UNIVERSITY   (Japan)

^b Itabashi Chuo Medical Center   (Japan)

Author keywords

Acute ischemic stroke; antihypertensive treatment; candesartan; neurologic symptoms; perindopril

Indexed keywords

CANDESARTAN HEXETIL; NITRATE; PERINDOPRIL;

AGED; ARTICLE; BLOOD PRESSURE REGULATION; BRAIN ISCHEMIA; CONTROLLED STUDY; COUGHING; DIASTOLIC BLOOD PRESSURE; DIZZINESS; FEMALE; HUMAN; HYPERTENSION; MAJOR CLINICAL STUDY; MALE; NEUROLOGIC DISEASE; PRIORITY JOURNAL; RENIN ANGIOTENSIN ALDOSTERONE SYSTEM; SYSTOLIC BLOOD PRESSURE;

ADMINISTRATION, ORAL; ADMINISTRATION, TOPICAL; AGED; AGED, 80 AND OVER; ANALYSIS OF VARIANCE; ANGIOTENSIN II TYPE 1 RECEPTOR BLOCKERS; ANGIOTENSIN-CONVERTING ENZYME INHIBITORS; ANTIHYPERTENSIVE AGENTS; BENZIMIDAZOLES; BLOOD PRESSURE; BRAIN ISCHEMIA; CHI-SQUARE DISTRIBUTION; DISABILITY EVALUATION; FEMALE; HUMANS; HYPERTENSION; JAPAN; MALE; MIDDLE AGED; NITRATES; PERINDOPRIL; RENIN-ANGIOTENSIN SYSTEM; STROKE; TETRAZOLES; TIME FACTORS; TREATMENT OUTCOME; VASODILATOR AGENTS;

EID: 78049468275     PISSN: 10523057     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jstrokecerebrovasdis.2009.08.006     Document Type: Article

References (25)

1. T.G. Robinson, S.L. Dawson, and U. Ahmed Twenty-four hour systolic blood pressure predicts long-term mortality following acute stroke J Hypertens 19 2001 2127 2134
2. J. Leonardi-Bee, P.M.W. Bath, S.J. Phillips for the IST Collaborative Group Blood pressure and clinical outcomes in the International Stroke Trial Stroke 33 2002 1315 1320
3. J.L. Rodriguez-Garcia, E. Botia, and A. de La Sierra Significance of elevated blood pressure and its management on the short-term outcome of patients with acute ischemic stroke Am J Hypertens 18 2005 379 384
4. H. Adams, R. Adams, and G. Del Zoppo Guidelines for the early management of patients with ischemic stroke: A scientific statement from the Stroke Council of the American Heart Association/American Stroke Association Stroke 36 2005 916 921
5. D.I. Graham, A. McGeorge, and W. Fitch Ischemic brain damage induced by rapid lowering of arterial pressure in hypertension J Hypertens 2 1984 297 304
6. S. Vorstrup, O.B. Paulson, and N.A. Lassen Cerebral blood flow in acute and chronic ischemic stroke using xenon-133 inhalation tomography Acta Neurol Scand 74 1986 439 451
7. S.L. Dawson, M.J. Blake, and R.B. Panerai Dynamic but not static cerebral autoregulation is impaired in acute ischemic stroke Cerebrovasc Dis 10 2000 126 132
8. D.H. Barer, J.M. Cruickshank, and S.B. Ebrahim Low-dose β blockade in acute stroke (BEST Trial): An evaluation Br Med J 296 1988 737 741
9. N. Ahmed, P. Nasman, and N.G. Wahlgren Effect of intravenous nimodipine on blood pressure and outcome after acute stroke Stroke 31 2000 1250 1255
10. P.J. Eames, T.G. Robinson, and R.B. Panerai The systemic haemodynamic and cerebral autoregulatory effects of bendrofluazide in the subacute post-stroke period J Hypertens 22 2004 2017 2024
11. M. Willmot, A. Ghadami, and B. Whysall Transdermal glyceryl trinitrate lowers blood pressure and maintains cerebral blood flow in recent stroke Hypertenstion 47 2006 1209 1215
12. D.J. Eveson, T.G. Robinson, and J.F. Potter Lisinopril for the treatment of hypertension within the first 24 hours of acute ischemic stroke and follow-up Am J Hypertens 20 2007 270 277
13. J.F. Potter, T.G. Robinson, and G.A. Ford Controlling hypertension and hypotension immediately post-stroke (CHHIPS): A randomized, placebo-controlled, double-blind pilot trial Lancet Neurol 8 2009 48 56
14. J. Schrader, S. Luders, and A. Kulschewski The ACCESS Study: Evaluation of acute candesartan cilexetil therapy in stroke survivors Stroke 34 2003 1699 1703
15. K. Minematsu, T. Yamaguchi, and M. Tsuchiya Effect of angiotensin-converting enzyme inhibitor (captopril) on cerebral blood flow in hypertensive patients without a history of stroke Clin Exp Hypertens 9 1987 551 557
16. A.G. Dyker, D.G. Grosset, and K. Lees Perindopril reduces blood pressure but not cerebral blood flow in patients with recent cerebral ischemic stroke Stroke 28 1997 580 583
17. J. Hatazawa, E. Shimosegawa, and Y. Osaki Long-term angiotensin- converting enzyme inhibitor perindopril therapy improves cerebral perfusion reserve in patients with previous minor stroke Stroke 35 2004 2117 2122
18. M.R. Walters, A. Bolster, and A.G. Dyker Effect of perindopril on cerebral and renal perfusion in stroke patients with carotid disease Stroke 32 2001 473 478
19. H.P. Adams, B.H. Bendixen, and L.J. Kappelle the TOAST Investigators. Classification of subtype of acute ischemic stroke: Definitions for use in a multicenter clinical trial Stroke 24 1993 35 41
20. 1) receptor blockade in hypertensive women: Benefits of candesartan cilexetil versus enalapril or hydrochlorothiazide Am J Hypertens 13 2000 504 511
21. K. Nakamura, Y. Saku, and S. Ibayashi Progressive motor deficits in lacunar infarction Neurology 52 1999 29 33
22. Y. Nishimura, T. Ito, and J.M. Saavedra Angiotensin II AT1 blockade normalizes cerebrovascular autoregulation and reduces cerebral ischemia in spontaneously hypertensive rats Stroke 31 2000 2478 2486
23. M. Iwai, H.W. Liu, and R. Chen Possible inhibition of focal cerebral ischemia by angiotensin II type 2 receptor stimulation Circulation 110 2004 843 848
24. S.C. Fagan, A. Kozak, and W.D. Hill Hypertension after experimental cerebral ischemia: Candesartan provides neurovascular protection J Hypertens 24 2006 535 539
25. R. Fogelholm, H. Palomaki, and T. Erila Blood pressure, nimodipine, and outcome of ischemic stroke Acta Neurol Scand 109 2004 200 204