Drug-induced liver injury: Is it time for genetics to change our clinical practice?

Journal of Hepatology

Volumn 53, Issue 6, 2010, Pages 993-994

  Invernizzi, Pietro ^a  

^a HUMANITAS CLINICAL AND RESEARCH CENTER   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

AMOXICILLIN PLUS CLAVULANIC ACID; FLUCLOXACILLIN; HLA DQB1 ANTIGEN; HLA DR ANTIGEN;

ALLELE; CLINICAL PRACTICE; DIARRHEA; EDITORIAL; GENE IDENTIFICATION; GENETIC ASSOCIATION; GENETIC RISK; GENETICS; HUMAN; PREDICTION; PRIORITY JOURNAL; PSEUDOMEMBRANOUS COLITIS; RISK FACTOR; SINGLE NUCLEOTIDE POLYMORPHISM; THRUSH; TOXIC HEPATITIS; VOMITING;

AMOXICILLIN-POTASSIUM CLAVULANATE COMBINATION; ANTI-BACTERIAL AGENTS; DRUG-INDUCED LIVER INJURY; GENETIC PREDISPOSITION TO DISEASE; HLA ANTIGENS; HUMANS;

EID: 78049465935     PISSN: 01688278     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jhep.2010.08.002     Document Type: Editorial

References (19)

1. J.W. van den Broek, B.L. Buennemeyer, and B.H. Stricker Cholestatic hepatitis caused by a combination of amoxicillin and clavulanic acid (Augmentin) Ned Tijdschr Geneeskd 132 1988 1495 1497
2. R.J. Andrade, M.I. Lucena, M.C. Fernandez, G. Pelaez, K. Pachkoria, and E. Garcia-Ruiz Drug-induced liver injury: an analysis of 461 incidences submitted to the Spanish registry over a 10-year period Gastroenterology 129 2005 512 521
3. N. Chalasani, R.J. Fontana, H.L. Bonkovsky, P.B. Watkins, T. Davern, and J. Serrano Causes, clinical features, and outcomes from a prospective study of drug-induced liver injury in the United States Gastroenterology 135 2008 1924 1934 (1934 e1921-1924)
4. N. Kaplowitz Idiosyncratic drug hepatotoxicity Nat Rev Drug Discov 4 2005 489 499
5. S. Verma, and N. Kaplowitz Diagnosis, management and prevention of drug-induced liver injury Gut 58 2009 1555 1564
6. Y. Meier, M. Cavallaro, M. Roos, C. Pauli-Magnus, G. Folkers, and P.J. Meier Incidence of drug-induced liver injury in medical inpatients Eur J Clin Pharmacol 61 2005 135 143
7. C. Sgro, F. Clinard, K. Ouazir, H. Chanay, C. Allard, and C. Guilleminet Incidence of drug-induced hepatic injuries: a French population-based study Hepatology 36 2002 451 455
8. M.M. Ong, C. Latchoumycandane, and U.A. Boelsterli Troglitazone-induced hepatic necrosis in an animal model of silent genetic mitochondrial abnormalities Toxicol Sci 97 2007 205 213
9. A.K. Daly, and C.P. Day Genetic association studies in drug-induced liver injury Semin Liver Dis 29 2009 400 411
10. P. Invernizzi Future directions in genetic for autoimmune diseases J Autoimmun 33 2009 1 2
11. P. Invernizzi, and M.E. Gershwin The genetics of human autoimmune disease J Autoimmun 33 2009 290 299
12. M.L. Hautekeete, Y. Horsmans, C. Van Waeyenberge, C. Demanet, J. Henrion, and L. Verbist HLA association of amoxicillin-clavulanate-induced hepatitis Gastroenterology 117 1999 1181 1186
13. J. O'Donohue, K.A. Oien, P. Donaldson, J. Underhill, M. Clare, and R.N. MacSween Co-amoxiclav jaundice: clinical and histological features and HLA class II association Gut 47 2000 717 720
14. P.T. Donaldson, A.K. Daly, J. Henderson, J. Graham, M. Pirmohamed, and W. Bernal Human leucocyte antigen class II genotype in susceptibility and resistance to co-amoxiclav-induced liver injury J Hepatol 53 2010 1049 1053
15. R.J. Andrade, M.I. Lucena, A. Alonso, M. Garcia-Cortes, E. Garcia-Ruiz, and R. Benitez HLA class II genotype influences the type of liver injury in drug-induced idiosyncratic liver disease Hepatology 39 2004 1603 1612
16. A.K. Daly, P.T. Donaldson, P. Bhatnagar, Y. Shen, I. Pe'er, and A. Floratos HLA-B5701 genotype is a major determinant of drug-induced liver injury due to flucloxacillin Nat Genet 41 2009 816 819
17. J. Klein, and A. Sato The HLA system. First of two parts N Engl J Med 343 2000 702 709
18. J. Klein, and A. Sato The HLA system. Second of two parts N Engl J Med 343 2000 782 786
19. S. Russmann, A. Jetter, and G.A. Kullak-Ublick Pharmacogenetics of drug-induced liver injury Hepatology 52 2010 748 761