-
1
-
-
35148881670
-
How effective are disease-modifying drugs in delaying progression in relapsing-onset MS?
-
M.G. Brown, S. Kirby, C. Skedgel, J.D. Fisk, T.J. Murray, and V. Bhan How effective are disease-modifying drugs in delaying progression in relapsing-onset MS? Neurology 69 2007 1498 1507
-
(2007)
Neurology
, vol.69
, pp. 1498-1507
-
-
Brown, M.G.1
Kirby, S.2
Skedgel, C.3
Fisk, J.D.4
Murray, T.J.5
Bhan, V.6
-
2
-
-
33644974688
-
Secondary progressive multiple sclerosis: Current knowledge and future challenges
-
M. Rovaris, C. Confavreux, R. Furlan, L. Kappos, G. Comi, and M. Filippi Secondary progressive multiple sclerosis: current knowledge and future challenges Lancet Neurol 5 2006 343 354
-
(2006)
Lancet Neurol
, vol.5
, pp. 343-354
-
-
Rovaris, M.1
Confavreux, C.2
Furlan, R.3
Kappos, L.4
Comi, G.5
Filippi, M.6
-
3
-
-
34247608145
-
New natural history of interferon-beta-treated relapsing multiple sclerosis
-
M. Trojano, F. Pellegrini, A. Fuiani, D. Paolicelli, V. Zipoli, and G.B. Zimatore New natural history of interferon-beta-treated relapsing multiple sclerosis Ann Neurol 61 2007 300 306
-
(2007)
Ann Neurol
, vol.61
, pp. 300-306
-
-
Trojano, M.1
Pellegrini, F.2
Fuiani, A.3
Paolicelli, D.4
Zipoli, V.5
Zimatore, G.B.6
-
4
-
-
38349186321
-
Intense immunosuppression in patients with rapidly worsening multiple sclerosis: Treatment guidelines for the clinician
-
A. Boster, G. Edan, E. Frohman, A. Javed, O. Stuve, and A. Tselis Intense immunosuppression in patients with rapidly worsening multiple sclerosis: treatment guidelines for the clinician Lancet Neurol 7 2008 173 183
-
(2008)
Lancet Neurol
, vol.7
, pp. 173-183
-
-
Boster, A.1
Edan, G.2
Frohman, E.3
Javed, A.4
Stuve, O.5
Tselis, A.6
-
5
-
-
33745285962
-
Management of worsening multiple sclerosis with mitoxantrone: A review
-
E.J. Fox Management of worsening multiple sclerosis with mitoxantrone: a review Clin Ther 28 2006 461 474
-
(2006)
Clin Ther
, vol.28
, pp. 461-474
-
-
Fox, E.J.1
-
6
-
-
67349250932
-
The efficacy of natalizumab in patients with relapsing multiple sclerosis: Subgroup analyses of AFFIRM and SENTINEL
-
M. Hutchinson, L. Kappos, P.A. Calabresi, C. Confavreux, G. Giovannoni, and S.L. Galetta The efficacy of natalizumab in patients with relapsing multiple sclerosis: subgroup analyses of AFFIRM and SENTINEL J Neurol 256 2009 405 415
-
(2009)
J Neurol
, vol.256
, pp. 405-415
-
-
Hutchinson, M.1
Kappos, L.2
Calabresi, P.A.3
Confavreux, C.4
Giovannoni, G.5
Galetta, S.L.6
-
8
-
-
33644584352
-
A randomized, placebo-controlled trial of natalizumab for relapsing multiple sclerosis
-
C.H. Polman, P.W. O'Connor, E. Havrdova, M. Hutchinson, L. Kappos, and D.H. Miller A randomized, placebo-controlled trial of natalizumab for relapsing multiple sclerosis N Engl J Med 354 2006 899 910
-
(2006)
N Engl J Med
, vol.354
, pp. 899-910
-
-
Polman, C.H.1
O'Connor, P.W.2
Havrdova, E.3
Hutchinson, M.4
Kappos, L.5
Miller, D.H.6
-
9
-
-
33644608613
-
Natalizumab plus interferon beta-1a for relapsing multiple sclerosis
-
R.A. Rudick, W.H. Stuart, P.A. Calabresi, C. Confavreux, S.L. Galetta, and E.W. Radue Natalizumab plus interferon beta-1a for relapsing multiple sclerosis N Engl J Med 354 2006 911 923
-
(2006)
N Engl J Med
, vol.354
, pp. 911-923
-
-
Rudick, R.A.1
Stuart, W.H.2
Calabresi, P.A.3
Confavreux, C.4
Galetta, S.L.5
Radue, E.W.6
-
11
-
-
0037153729
-
Mitoxantrone in progressive multiple sclerosis: A placebo-controlled, double-blind, randomised, multicentre trial
-
H.P. Hartung, R. Gonsette, N. Konig, H. Kwiecinski, A. Guseo, and S.P. Morrissey Mitoxantrone in progressive multiple sclerosis: a placebo-controlled, double-blind, randomised, multicentre trial Lancet 360 2002 2018 2025
-
(2002)
Lancet
, vol.360
, pp. 2018-2025
-
-
Hartung, H.P.1
Gonsette, R.2
Konig, N.3
Kwiecinski, H.4
Guseo, A.5
Morrissey, S.P.6
-
12
-
-
24644485224
-
Effect of mitoxantrone on MRI in progressive MS: Results of the MIMS trial
-
H. Krapf, S.P. Morrissey, O. Zenker, T. Zwingers, R. Gonsette, and H.P. Hartung Effect of mitoxantrone on MRI in progressive MS: results of the MIMS trial Neurology 65 2005 690 695
-
(2005)
Neurology
, vol.65
, pp. 690-695
-
-
Krapf, H.1
Morrissey, S.P.2
Zenker, O.3
Zwingers, T.4
Gonsette, R.5
Hartung, H.P.6
-
13
-
-
28444470149
-
Therapeutic role of mitoxantrone in multiple sclerosis
-
O. Neuhaus, B.C. Kieseier, and H.P. Hartung Therapeutic role of mitoxantrone in multiple sclerosis Pharmacol Ther 109 2006 198 209
-
(2006)
Pharmacol Ther
, vol.109
, pp. 198-209
-
-
Neuhaus, O.1
Kieseier, B.C.2
Hartung, H.P.3
-
14
-
-
0036200216
-
Results of an international questionnaire on immunosuppressive treatment of multiple sclerosis
-
O.R. Hommes, and H.L. Weiner Results of an international questionnaire on immunosuppressive treatment of multiple sclerosis Mult Scler 8 2002 139 141
-
(2002)
Mult Scler
, vol.8
, pp. 139-141
-
-
Hommes, O.R.1
Weiner, H.L.2
-
15
-
-
3142630125
-
Clinical practice of immunosuppressive treatments in multiple sclerosis: Results of a second international questionnaire
-
O.R. Hommes, and H.L. Weiner Clinical practice of immunosuppressive treatments in multiple sclerosis: results of a second international questionnaire J Neurol Sci 223 2004 65 67
-
(2004)
J Neurol Sci
, vol.223
, pp. 65-67
-
-
Hommes, O.R.1
Weiner, H.L.2
-
16
-
-
0037324814
-
Rapid onset mitoxantrone-induced cardiotoxicity in secondary progressive multiple sclerosis
-
J.R. Avasarala, A.H. Cross, D.B. Clifford, B.A. Singer, B.A. Siegel, and E.E. Abbey Rapid onset mitoxantrone-induced cardiotoxicity in secondary progressive multiple sclerosis Mult Scler 9 2003 59 62
-
(2003)
Mult Scler
, vol.9
, pp. 59-62
-
-
Avasarala, J.R.1
Cross, A.H.2
Clifford, D.B.3
Singer, B.A.4
Siegel, B.A.5
Abbey, E.E.6
-
17
-
-
0037167538
-
Cardiac adverse effects associated with mitoxantrone (Novantrone) therapy in patients with MS
-
R.G. Ghalie, G. Edan, M. Laurent, E. Mauch, S. Eisenman, and H.P. Hartung Cardiac adverse effects associated with mitoxantrone (Novantrone) therapy in patients with MS Neurology 59 2002 909 913
-
(2002)
Neurology
, vol.59
, pp. 909-913
-
-
Ghalie, R.G.1
Edan, G.2
Laurent, M.3
Mauch, E.4
Eisenman, S.5
Hartung, H.P.6
-
18
-
-
26644447135
-
Severe delayed heart failure in three multiple sclerosis patients previously treated with mitoxantrone
-
S. Goffette, V. van Pesch, J.L. Vanoverschelde, E. Morandini, and C.J. Sindic Severe delayed heart failure in three multiple sclerosis patients previously treated with mitoxantrone J Neurol 252 2005 1217 1222
-
(2005)
J Neurol
, vol.252
, pp. 1217-1222
-
-
Goffette, S.1
Van Pesch, V.2
Vanoverschelde, J.L.3
Morandini, E.4
Sindic, C.J.5
-
19
-
-
2342517243
-
Heart transplantation in a patient with multiple sclerosis and mitoxantrone-induced cardiomyopathy
-
H. Nagele, M.A. Castel, O. Deutsch, F.M. Wagner, and H. Reichenspurner Heart transplantation in a patient with multiple sclerosis and mitoxantrone-induced cardiomyopathy J Heart Lung Transplant 23 2004 641 643
-
(2004)
J Heart Lung Transplant
, vol.23
, pp. 641-643
-
-
Nagele, H.1
Castel, M.A.2
Deutsch, O.3
Wagner, F.M.4
Reichenspurner, H.5
-
20
-
-
33846856684
-
Early mitoxantrone-induced cardiotoxicity in secondary progressive multiple sclerosis
-
F. Paul, J. Dorr, J. Wurfel, H.P. Vogel, and F. Zipp Early mitoxantrone-induced cardiotoxicity in secondary progressive multiple sclerosis J Neurol Neurosurg Psychiatry 78 2007 198 200
-
(2007)
J Neurol Neurosurg Psychiatry
, vol.78
, pp. 198-200
-
-
Paul, F.1
Dorr, J.2
Wurfel, J.3
Vogel, H.P.4
Zipp, F.5
-
21
-
-
77950480232
-
Severe cardiac failure in a patient with multiple sclerosis following low-dose mitoxantrone treatment
-
J. Killestein, M.L. Van der Meer, J.C. Regelink, P.C. Huijgens, and C.H. Polman Severe cardiac failure in a patient with multiple sclerosis following low-dose mitoxantrone treatment Neurology 74 2010 934
-
(2010)
Neurology
, vol.74
, pp. 934
-
-
Killestein, J.1
Van Der Meer, M.L.2
Regelink, J.C.3
Huijgens, P.C.4
Polman, C.H.5
-
22
-
-
70349667038
-
Severe cardiac failure in a patient with multiple sclerosis following low-dose mitoxantrone treatment
-
J. Dörr, A. Bitsch, K.J. Schmailzl, A. Chan, N. Von Ahsen, and M. Hummel Severe cardiac failure in a patient with multiple sclerosis following low-dose mitoxantrone treatment Neurology 73 2009 991 993
-
(2009)
Neurology
, vol.73
, pp. 991-993
-
-
Dörr, J.1
Bitsch, A.2
Schmailzl, K.J.3
Chan, A.4
Von Ahsen, N.5
Hummel, M.6
-
23
-
-
24944493605
-
Assessment of potential cardiotoxic side effects of mitoxantrone in patients with multiple sclerosis
-
V.C. Zingler, M. Nabauer, K. Jahn, A. Gross, R. Hohlfeld, and T. Brandt Assessment of potential cardiotoxic side effects of mitoxantrone in patients with multiple sclerosis Eur Neurol 54 2005 28 33
-
(2005)
Eur Neurol
, vol.54
, pp. 28-33
-
-
Zingler, V.C.1
Nabauer, M.2
Jahn, K.3
Gross, A.4
Hohlfeld, R.5
Brandt, T.6
-
24
-
-
0037323227
-
Severe heart failure in a young multiple sclerosis patient
-
J. Gbadamosi, A. Munchau, C. Weiller, and H. Schafer Severe heart failure in a young multiple sclerosis patient J Neurol 250 2003 241 242
-
(2003)
J Neurol
, vol.250
, pp. 241-242
-
-
Gbadamosi, J.1
Munchau, A.2
Weiller, C.3
Schafer, H.4
-
26
-
-
48949116325
-
Acute myeloid leukemia induced by mitoxantrone treatment for aggressive multiple sclerosis
-
M. Capobianco, S. Malucchi, S. Ulisciani, C. Fava, G.R. Cambrin, and L. Avonto Acute myeloid leukemia induced by mitoxantrone treatment for aggressive multiple sclerosis Neurol Sci 29 2008 185 187
-
(2008)
Neurol Sci
, vol.29
, pp. 185-187
-
-
Capobianco, M.1
Malucchi, S.2
Ulisciani, S.3
Fava, C.4
Cambrin, G.R.5
Avonto, L.6
-
27
-
-
63449128972
-
Therapy-related acute leukaemia with Mitoxantrone: What is the risk and can we minimise it?
-
R. Ellis, and M. Boggild Therapy-related acute leukaemia with Mitoxantrone: what is the risk and can we minimise it? Mult Scler 15 2009 505 508
-
(2009)
Mult Scler
, vol.15
, pp. 505-508
-
-
Ellis, R.1
Boggild, M.2
-
28
-
-
0036783808
-
A study of therapy-related acute leukaemia after mitoxantrone therapy for multiple sclerosis
-
R.G. Ghalie, E. Mauch, G. Edan, H.P. Hartung, R.E. Gonsette, and S. Eisenmann A study of therapy-related acute leukaemia after mitoxantrone therapy for multiple sclerosis Mult Scler 8 2002 441 445
-
(2002)
Mult Scler
, vol.8
, pp. 441-445
-
-
Ghalie, R.G.1
Mauch, E.2
Edan, G.3
Hartung, H.P.4
Gonsette, R.E.5
Eisenmann, S.6
-
29
-
-
4444233652
-
Acute promyelocytic leukemia in a patient with multiple sclerosis following treatment with mitoxantrone
-
A.V. Novoselac, S. Reddy, and J. Sanmugarajah Acute promyelocytic leukemia in a patient with multiple sclerosis following treatment with mitoxantrone Leukemia 18 2004 1561 1562
-
(2004)
Leukemia
, vol.18
, pp. 1561-1562
-
-
Novoselac, A.V.1
Reddy, S.2
Sanmugarajah, J.3
-
30
-
-
57549089217
-
Mitoxantrone-related acute leukemia in two MS patients
-
A. Pielen, S. Goffette, V. Van Pesch, M. Gille, and C.J. Sindic Mitoxantrone-related acute leukemia in two MS patients Acta Neurol Belg 108 2008 99 102
-
(2008)
Acta Neurol Belg
, vol.108
, pp. 99-102
-
-
Pielen, A.1
Goffette, S.2
Van Pesch, V.3
Gille, M.4
Sindic, C.J.5
-
31
-
-
43149125464
-
Chronic myeloid leukemia associated with mitoxantrone treatment in a patient with MS
-
S.A. Sadiq, M. Rammal, and G. Sara Chronic myeloid leukemia associated with mitoxantrone treatment in a patient with MS Mult Scler 14 2008 272 273
-
(2008)
Mult Scler
, vol.14
, pp. 272-273
-
-
Sadiq, S.A.1
Rammal, M.2
Sara, G.3
-
32
-
-
35748980015
-
Therapy-related acute nonlymphoblastic leukemia following mitoxantrone therapy in a patient with multiple sclerosis
-
A. Sumrall, and B. Dreiling Therapy-related acute nonlymphoblastic leukemia following mitoxantrone therapy in a patient with multiple sclerosis J Miss State Med Assoc 48 2007 206 207
-
(2007)
J Miss State Med Assoc
, vol.48
, pp. 206-207
-
-
Sumrall, A.1
Dreiling, B.2
-
33
-
-
3042535824
-
Acute myeloid leukaemia induced by mitoxantrone in a multiple sclerosis patient
-
R. Tanasescu, M. Debouverie, S. Pittion, R. Anxionnat, and H. Vespignani Acute myeloid leukaemia induced by mitoxantrone in a multiple sclerosis patient J Neurol 251 2004 762 763
-
(2004)
J Neurol
, vol.251
, pp. 762-763
-
-
Tanasescu, R.1
Debouverie, M.2
Pittion, S.3
Anxionnat, R.4
Vespignani, H.5
-
34
-
-
4344569251
-
Mitoxantrone therapy in multiple sclerosis and acute leukaemia: A case report out of 644 treated patients
-
R. Voltz, M. Starck, V. Zingler, M. Strupp, and H.J. Kolb Mitoxantrone therapy in multiple sclerosis and acute leukaemia: a case report out of 644 treated patients Mult Scler 10 2004 472 474
-
(2004)
Mult Scler
, vol.10
, pp. 472-474
-
-
Voltz, R.1
Starck, M.2
Zingler, V.3
Strupp, M.4
Kolb, H.J.5
-
35
-
-
70450176057
-
Revision of the risk of secondary leukaemia after mitoxantrone in multiple sclerosis populations is required
-
A.M. Pascual, N. Téllez, I. Boscá, J. Mallada, A. Belenguer, and I. Abellán Revision of the risk of secondary leukaemia after mitoxantrone in multiple sclerosis populations is required Mult Scler 15 2009 1303 1310
-
(2009)
Mult Scler
, vol.15
, pp. 1303-1310
-
-
Pascual, A.M.1
Téllez, N.2
Boscá, I.3
Mallada, J.4
Belenguer, A.5
Abellán, I.6
-
37
-
-
77951828930
-
Evidence report: The efficacy and safety of mitoxantrone (Novantrone) in the treatment of multiple sclerosis: Report of the Therapeutics and Technology Assessment Subcommittee of the American Academy of Neurology
-
J.J. Marriott, J.M. Miyasaki, G. Gronseth, and P.W. O'Connor Evidence report: the efficacy and safety of mitoxantrone (Novantrone) in the treatment of multiple sclerosis: Report of the Therapeutics and Technology Assessment Subcommittee of the American Academy of Neurology Neurology 74 2010 1463 1470
-
(2010)
Neurology
, vol.74
, pp. 1463-1470
-
-
Marriott, J.J.1
Miyasaki, J.M.2
Gronseth, G.3
O'Connor, P.W.4
-
38
-
-
77953206986
-
Cardiotoxicity and other adverse events associated with mitoxantrone treatment for MS
-
E. Kingwell, M. Koch, B. Leung, S. Isserow, J. Geddes, and P. Rieckmann Cardiotoxicity and other adverse events associated with mitoxantrone treatment for MS Neurology 74 2010 1822 1826
-
(2010)
Neurology
, vol.74
, pp. 1822-1826
-
-
Kingwell, E.1
Koch, M.2
Leung, B.3
Isserow, S.4
Geddes, J.5
Rieckmann, P.6
-
39
-
-
59249103269
-
Immunosuppression followed by immunomodulation
-
M. Boggild Immunosuppression followed by immunomodulation J Neurol Sci 277 2009 S50 S54
-
(2009)
J Neurol Sci
, vol.277
-
-
Boggild, M.1
-
40
-
-
17044391471
-
Mitoxantrone as rescue therapy in worsening relapsing-remitting MS patients receiving IFN-beta
-
J. Correale, C. Rush, A. Amengual, and M.T. Goicochea Mitoxantrone as rescue therapy in worsening relapsing-remitting MS patients receiving IFN-beta J Neuroimmunol 162 2005 173 183
-
(2005)
J Neuroimmunol
, vol.162
, pp. 173-183
-
-
Correale, J.1
Rush, C.2
Amengual, A.3
Goicochea, M.T.4
-
41
-
-
59249100416
-
Long-term experience with induction treatment regimens in multiple sclerosis
-
E. Le Page, and G. Edan Long-term experience with induction treatment regimens in multiple sclerosis J Neurol Sci 277 2009 S46 S49
-
(2009)
J Neurol Sci
, vol.277
-
-
Le Page, E.1
Edan, G.2
-
42
-
-
37749016994
-
Mitoxantrone as induction treatment in aggressive relapsing remitting multiple sclerosis: Treatment response factors in a 5-year follow-up observational study of 100 consecutive patients
-
E. Le Page, E. Leray, G. Taurin, M. Coustans, J. Chaperon, and S.P. Morrissey Mitoxantrone as induction treatment in aggressive relapsing remitting multiple sclerosis: treatment response factors in a 5-year follow-up observational study of 100 consecutive patients J Neurol Neurosurg Psychiatry 79 2008 52 56
-
(2008)
J Neurol Neurosurg Psychiatry
, vol.79
, pp. 52-56
-
-
Le Page, E.1
Leray, E.2
Taurin, G.3
Coustans, M.4
Chaperon, J.5
Morrissey, S.P.6
-
43
-
-
33749432012
-
Sequential maintenance treatment with glatiramer acetate after mitoxantrone is safe and can limit exposure to immunosuppression in very active, relapsing remitting multiple sclerosis
-
J. Ramtahal, A. Jacob, K. Das, and M. Boggild Sequential maintenance treatment with glatiramer acetate after mitoxantrone is safe and can limit exposure to immunosuppression in very active, relapsing remitting multiple sclerosis J Neurol 253 2006 1160 1164
-
(2006)
J Neurol
, vol.253
, pp. 1160-1164
-
-
Ramtahal, J.1
Jacob, A.2
Das, K.3
Boggild, M.4
-
44
-
-
46849091551
-
Glatiramer acetate after induction therapy with mitoxantrone in relapsing multiple sclerosis
-
T. Vollmer, H. Panitch, A. Bar-Or, J. Dunn, M.S. Freedman, and S.K. Gazda Glatiramer acetate after induction therapy with mitoxantrone in relapsing multiple sclerosis Mult Scler 14 2008 663 670
-
(2008)
Mult Scler
, vol.14
, pp. 663-670
-
-
Vollmer, T.1
Panitch, H.2
Bar-Or, A.3
Dunn, J.4
Freedman, M.S.5
Gazda, S.K.6
-
45
-
-
53649090647
-
Induction and add-on therapy with mitoxantrone and interferon beta in multiple sclerosis
-
M. Zaffaroni, A. Rizzo, S.M. Baldini, A. Ghezzi, and G. Comi Induction and add-on therapy with mitoxantrone and interferon beta in multiple sclerosis Neurol Sci 29 2008 S230 S232
-
(2008)
Neurol Sci
, vol.29
-
-
Zaffaroni, M.1
Rizzo, A.2
Baldini, S.M.3
Ghezzi, A.4
Comi, G.5
-
46
-
-
4344594349
-
Predictive parameters of mitoxantrone effectiveness in the treatment of multiple sclerosis
-
M. Debouverie, N. Vandenberghe, S.P. Morrissey, R. Anxionnat, S. Pittion-Vouyovitch, and H. Vespignani Predictive parameters of mitoxantrone effectiveness in the treatment of multiple sclerosis Mult Scler 10 2004 407 412
-
(2004)
Mult Scler
, vol.10
, pp. 407-412
-
-
Debouverie, M.1
Vandenberghe, N.2
Morrissey, S.P.3
Anxionnat, R.4
Pittion-Vouyovitch, S.5
Vespignani, H.6
-
47
-
-
0031040238
-
Therapeutic effect of mitoxantrone combined with methylprednisolone in multiple sclerosis: A randomised multicentre study of active disease using MRI and clinical criteria
-
G. Edan, D. Miller, M. Clanet, C. Confavreux, O. Lyon-Caen, and C. Lubetzki Therapeutic effect of mitoxantrone combined with methylprednisolone in multiple sclerosis: a randomised multicentre study of active disease using MRI and clinical criteria J Neurol Neurosurg Psychiatry 62 1997 112 118
-
(1997)
J Neurol Neurosurg Psychiatry
, vol.62
, pp. 112-118
-
-
Edan, G.1
Miller, D.2
Clanet, M.3
Confavreux, C.4
Lyon-Caen, O.5
Lubetzki, C.6
|