메뉴 건너뛰기




Volumn 175, Issue 1, 2011, Pages 68-75

Silencing of a putative inner arm dynein heavy chain results in flagellar immotility in Trypanosoma brucei

Author keywords

Axoneme; Dynein heavy chain; Flagellar motility; Inner arm dynein; Trypanosoma

Indexed keywords

DYNEIN ADENOSINE TRIPHOSPHATASE;

EID: 78049451742     PISSN: 01666851     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.molbiopara.2010.09.005     Document Type: Article
Times cited : (15)

References (50)
  • 2
    • 34249650299 scopus 로고    scopus 로고
    • Stuck in reverse: loss of LC1 in Trypanosoma brucei disrupts outer dynein arms and leads to reverse flagellar beat and backward movement
    • Baron D.M., Kabututu Z.P., Hill K.L. Stuck in reverse: loss of LC1 in Trypanosoma brucei disrupts outer dynein arms and leads to reverse flagellar beat and backward movement. J Cell Sci 2007, 120:1513-1520.
    • (2007) J Cell Sci , vol.120 , pp. 1513-1520
    • Baron, D.M.1    Kabututu, Z.P.2    Hill, K.L.3
  • 3
    • 0032484944 scopus 로고    scopus 로고
    • Paraflagellar rod is vital for trypanosome motility
    • Bastin P., Sherwin T., Gull K. Paraflagellar rod is vital for trypanosome motility. Nature 1998, 391:548.
    • (1998) Nature , vol.391 , pp. 548
    • Bastin, P.1    Sherwin, T.2    Gull, K.3
  • 4
    • 33748759561 scopus 로고    scopus 로고
    • Conserved and specific functions of axoneme components in trypanosome motility
    • Branche C., Kohl L., Toutirais G., Buisson J., Cosson J., Bastin P. Conserved and specific functions of axoneme components in trypanosome motility. J Cell Sci 2006, 119:3443-3455.
    • (2006) J Cell Sci , vol.119 , pp. 3443-3455
    • Branche, C.1    Kohl, L.2    Toutirais, G.3    Buisson, J.4    Cosson, J.5    Bastin, P.6
  • 5
    • 33644858832 scopus 로고    scopus 로고
    • Flagellar motility is required for the viability of the bloodstream trypanosome
    • Broadhead R., Dawe H.R., Farr H., et al. Flagellar motility is required for the viability of the bloodstream trypanosome. Nature 2006, 440:224-227.
    • (2006) Nature , vol.440 , pp. 224-227
    • Broadhead, R.1    Dawe, H.R.2    Farr, H.3
  • 6
    • 0023083510 scopus 로고
    • Bending patterns of Chlamydomonas flagella: IV. Mutants with defects in inner and outer dynein arms indicate differences in dynein arm function
    • Brokaw C.J., Kamiya R. Bending patterns of Chlamydomonas flagella: IV. Mutants with defects in inner and outer dynein arms indicate differences in dynein arm function. Cell Motil Cytoskeleton 1987, 8:68-75.
    • (1987) Cell Motil Cytoskeleton , vol.8 , pp. 68-75
    • Brokaw, C.J.1    Kamiya, R.2
  • 7
    • 0020690524 scopus 로고
    • Bending patterns of chlamydomonas flagella I. Wild-type bending patterns
    • Brokaw C.J., Luck D.J. Bending patterns of chlamydomonas flagella I. Wild-type bending patterns. Cell Motil 1983, 3:131-150.
    • (1983) Cell Motil , vol.3 , pp. 131-150
    • Brokaw, C.J.1    Luck, D.J.2
  • 8
    • 0018601361 scopus 로고
    • Cultivation and in vitro cloning of procyclic culture forms of Trypanosoma brucei in a semi-defined medium
    • Schönenberger
    • Brun R., Schönenberger Cultivation and in vitro cloning of procyclic culture forms of Trypanosoma brucei in a semi-defined medium. Acta Trop 1979, 36:289-292.
    • (1979) Acta Trop , vol.36 , pp. 289-292
    • Brun, R.1
  • 9
    • 58149291884 scopus 로고    scopus 로고
    • Molecular architecture of inner dynein arms in situ in Chlamydomonas reinhardtii flagella
    • Bui K.H., Sakakibara H., Movassagh T., Oiwa K., Ishikawa T. Molecular architecture of inner dynein arms in situ in Chlamydomonas reinhardtii flagella. J Cell Biol 2008, 183:923-932.
    • (2008) J Cell Biol , vol.183 , pp. 923-932
    • Bui, K.H.1    Sakakibara, H.2    Movassagh, T.3    Oiwa, K.4    Ishikawa, T.5
  • 11
    • 57349176187 scopus 로고    scopus 로고
    • Stem-loop silencing reveals that a third mitochondrial DNA polymerase. POLID, is required for kinetoplast DNA replication in trypanosomes
    • Chandler J., Vandoros A.V., Mozeleski B., Klingbeil M.M. Stem-loop silencing reveals that a third mitochondrial DNA polymerase. POLID, is required for kinetoplast DNA replication in trypanosomes. Eukaryot Cell 2008, 7:2141-2146.
    • (2008) Eukaryot Cell , vol.7 , pp. 2141-2146
    • Chandler, J.1    Vandoros, A.V.2    Mozeleski, B.3    Klingbeil, M.M.4
  • 12
    • 0031444202 scopus 로고    scopus 로고
    • An extended microtubule-binding structure within the dynein motor domain
    • Gee M.A., Heuser J.E., Vallee R.B. An extended microtubule-binding structure within the dynein motor domain. Nature 1997, 390:636-639.
    • (1997) Nature , vol.390 , pp. 636-639
    • Gee, M.A.1    Heuser, J.E.2    Vallee, R.B.3
  • 13
    • 0029084610 scopus 로고
    • Dynein family of motor proteins: present status and future questions
    • Gibbons I.R. Dynein family of motor proteins: present status and future questions. Cell Motil Cytoskeleton 1995, 32:136-144.
    • (1995) Cell Motil Cytoskeleton , vol.32 , pp. 136-144
    • Gibbons, I.R.1
  • 14
    • 0042195176 scopus 로고    scopus 로고
    • Host-parasite interactions and trypanosome morphogenesis: a flagellar pocketful of goodies
    • Gull K. Host-parasite interactions and trypanosome morphogenesis: a flagellar pocketful of goodies. Curr Opin Microbiol 2003, 6:365-370.
    • (2003) Curr Opin Microbiol , vol.6 , pp. 365-370
    • Gull, K.1
  • 15
    • 0038058958 scopus 로고    scopus 로고
    • Biology and mechanism of trypanosome cell motility
    • Hill K.L. Biology and mechanism of trypanosome cell motility. Eukaryot Cell 2003, 2:200-208.
    • (2003) Eukaryot Cell , vol.2 , pp. 200-208
    • Hill, K.L.1
  • 16
    • 34247211171 scopus 로고    scopus 로고
    • The architecture of outer dynein arms in situ
    • Ishikawa T., Sakakibara H., Oiwa K. The architecture of outer dynein arms in situ. J Mol Biol 2007, 368:1249-1258.
    • (2007) J Mol Biol , vol.368 , pp. 1249-1258
    • Ishikawa, T.1    Sakakibara, H.2    Oiwa, K.3
  • 17
    • 0026081647 scopus 로고
    • Two types of Chlamydomonas flagellar mutants missing different components of inner-arm dynein
    • Kamiya R., Kurimoto E., Muto E. Two types of Chlamydomonas flagellar mutants missing different components of inner-arm dynein. J Cell Biol 1991, 112:441-447.
    • (1991) J Cell Biol , vol.112 , pp. 441-447
    • Kamiya, R.1    Kurimoto, E.2    Muto, E.3
  • 18
    • 0021890914 scopus 로고
    • A mutant of Chlamydomonas reinhardtii that lacks the flagellar outer dynein arm but can swim
    • Kamiya R., Okamoto M. A mutant of Chlamydomonas reinhardtii that lacks the flagellar outer dynein arm but can swim. J Cell Sci 1985, 74:181-191.
    • (1985) J Cell Sci , vol.74 , pp. 181-191
    • Kamiya, R.1    Okamoto, M.2
  • 19
    • 43849097571 scopus 로고    scopus 로고
    • Clockwise translocation of microtubules by flagellar inner-arm dyneins in vitro
    • Kikushima K., Kamiya R. Clockwise translocation of microtubules by flagellar inner-arm dyneins in vitro. Biophys J 2008, 94:4014-4019.
    • (2008) Biophys J , vol.94 , pp. 4014-4019
    • Kikushima, K.1    Kamiya, R.2
  • 20
    • 0142105416 scopus 로고    scopus 로고
    • Novel roles for the flagellum in cell morphogenesis and cytokinesis of trypanosomes
    • Kohl L., Robinson D., Bastin P. Novel roles for the flagellum in cell morphogenesis and cytokinesis of trypanosomes. EMBO J 2003, 22:5336-5346.
    • (2003) EMBO J , vol.22 , pp. 5336-5346
    • Kohl, L.1    Robinson, D.2    Bastin, P.3
  • 21
    • 34547666969 scopus 로고    scopus 로고
    • Mechanical properties of inner-arm dynein-f (dynein I1) studied with in vitro motility assays
    • Kotani N., Sakakibara H., Burgess S.A., Kojima H., Oiwa K. Mechanical properties of inner-arm dynein-f (dynein I1) studied with in vitro motility assays. Biophys J 2007, 93:886-894.
    • (2007) Biophys J , vol.93 , pp. 886-894
    • Kotani, N.1    Sakakibara, H.2    Burgess, S.A.3    Kojima, H.4    Oiwa, K.5
  • 22
    • 0037124117 scopus 로고    scopus 로고
    • Trypanosoma brucei FLA1 is required for flagellum attachment and cytokinesis
    • LaCount D.J., Barrett B., Donelson J.E. Trypanosoma brucei FLA1 is required for flagellum attachment and cytokinesis. J Biol Chem 2002, 277:17580-17588.
    • (2002) J Biol Chem , vol.277 , pp. 17580-17588
    • LaCount, D.J.1    Barrett, B.2    Donelson, J.E.3
  • 23
    • 85012344312 scopus 로고
    • A motile Chlamydomonas flagellar mutant that lacks outer dynein arms
    • Mitchell D., Rosenbaum J. A motile Chlamydomonas flagellar mutant that lacks outer dynein arms. J Cell Biol 1985, 100:1228-1234.
    • (1985) J Cell Biol , vol.100 , pp. 1228-1234
    • Mitchell, D.1    Rosenbaum, J.2
  • 24
    • 70449603441 scopus 로고    scopus 로고
    • Searching for novel cell cycle regulators in Trypanosoma brucei with an RNA interference screen
    • Monnerat S., Clucas C., Brown E., Mottram J.C., Hammarton T.C. Searching for novel cell cycle regulators in Trypanosoma brucei with an RNA interference screen. BMC Res Notes 2009, 2:46.
    • (2009) BMC Res Notes , vol.2 , pp. 46
    • Monnerat, S.1    Clucas, C.2    Brown, E.3    Mottram, J.C.4    Hammarton, T.C.5
  • 25
    • 0030956345 scopus 로고    scopus 로고
    • The Chlamydomonas Dhc1 gene encodes a dynein heavy chain subunit required for assembly of the I1 inner arm complex
    • Myster S.H., Knott J.A., O'Toole E., Porter M.E. The Chlamydomonas Dhc1 gene encodes a dynein heavy chain subunit required for assembly of the I1 inner arm complex. Mol Biol Cell 1997, 8:607-620.
    • (1997) Mol Biol Cell , vol.8 , pp. 607-620
    • Myster, S.H.1    Knott, J.A.2    O'Toole, E.3    Porter, M.E.4
  • 26
    • 0033598021 scopus 로고    scopus 로고
    • Domains in the 1alpha dynein heavy chain required for inner arm assembly and flagellar motility in Chlamydomonas
    • Myster S.H., Knott J.A., Wysocki K.M., O'Toole E., Porter M.E. Domains in the 1alpha dynein heavy chain required for inner arm assembly and flagellar motility in Chlamydomonas. J Cell Biol 1999, 146:801-818.
    • (1999) J Cell Biol , vol.146 , pp. 801-818
    • Myster, S.H.1    Knott, J.A.2    Wysocki, K.M.3    O'Toole, E.4    Porter, M.E.5
  • 28
    • 77954662426 scopus 로고    scopus 로고
    • Approaches for functional analysis of flagellar proteins in African trypanosomes
    • Oberholzer M., Lopez M.A., Ralston K.S., Hill K.L. Approaches for functional analysis of flagellar proteins in African trypanosomes. Methods Cell Biol 2009, 93:21-57.
    • (2009) Methods Cell Biol , vol.93 , pp. 21-57
    • Oberholzer, M.1    Lopez, M.A.2    Ralston, K.S.3    Hill, K.L.4
  • 29
    • 17344392308 scopus 로고    scopus 로고
    • A new mathematical model for relative quantification in real-time RT-PCR
    • Pfaffl M.W. A new mathematical model for relative quantification in real-time RT-PCR. Nucleic Acids Res 2001, 29:e45.
    • (2001) Nucleic Acids Res , vol.29
    • Pfaffl, M.W.1
  • 30
    • 0034722338 scopus 로고    scopus 로고
    • The 9+2 axoneme anchors multiple inner arm dyneins and a network of kinases and phosphatases that control motility
    • Porter M.E., Sale W.S. The 9+2 axoneme anchors multiple inner arm dyneins and a network of kinases and phosphatases that control motility. J Cell Biol 2000, 151:F37-F42.
    • (2000) J Cell Biol , vol.151
    • Porter, M.E.1    Sale, W.S.2
  • 31
    • 33749528009 scopus 로고    scopus 로고
    • Trypanin, a component of the flagellar Dynein regulatory complex, is essential in bloodstream form African trypanosomes
    • Ralston K.S., Hill K.L. Trypanin, a component of the flagellar Dynein regulatory complex, is essential in bloodstream form African trypanosomes. PLoS Pathog 2006, 2:e101.
    • (2006) PLoS Pathog , vol.2
    • Ralston, K.S.1    Hill, K.L.2
  • 32
    • 43949146897 scopus 로고    scopus 로고
    • The flagellum of Trypanosoma brucei: new tricks from an old dog
    • Ralston K.S., Hill K.L. The flagellum of Trypanosoma brucei: new tricks from an old dog. Int J Parasitol 2008, 38:869-884.
    • (2008) Int J Parasitol , vol.38 , pp. 869-884
    • Ralston, K.S.1    Hill, K.L.2
  • 34
    • 33646272170 scopus 로고    scopus 로고
    • Flagellar motility contributes to cytokinesis in Trypanosoma brucei and is modulated by an evolutionarily conserved dynein regulatory system
    • Ralston K.S., Lerner A.G., Diener D.R., Hill K.L. Flagellar motility contributes to cytokinesis in Trypanosoma brucei and is modulated by an evolutionarily conserved dynein regulatory system. Eukaryot Cell 2006, 5:696-711.
    • (2006) Eukaryot Cell , vol.5 , pp. 696-711
    • Ralston, K.S.1    Lerner, A.G.2    Diener, D.R.3    Hill, K.L.4
  • 35
    • 0025735679 scopus 로고
    • Microtubules, tubulin, and microtubule-associated proteins of trypanosomes
    • Robinson D., Beattie P., Sherwin T., Gull K. Microtubules, tubulin, and microtubule-associated proteins of trypanosomes. Methods Enzymol 1991, 196:285-299.
    • (1991) Methods Enzymol , vol.196 , pp. 285-299
    • Robinson, D.1    Beattie, P.2    Sherwin, T.3    Gull, K.4
  • 36
    • 73349122646 scopus 로고    scopus 로고
    • Propulsion of African trypanosomes is driven by bihelical waves with alternating chirality separated by kinks
    • Rodríguez J.A., Lopez M.A., Thayer M.C., et al. Propulsion of African trypanosomes is driven by bihelical waves with alternating chirality separated by kinks. Proc Natl Acad Sci USA 2009, 106:19322-19327.
    • (2009) Proc Natl Acad Sci USA , vol.106 , pp. 19322-19327
    • Rodríguez, J.A.1    Lopez, M.A.2    Thayer, M.C.3
  • 37
    • 1642321118 scopus 로고    scopus 로고
    • Design and regulation of the AAA+ microtubule motor dynein
    • Sakato M., King S.M. Design and regulation of the AAA+ microtubule motor dynein. J Struct Biol 2004, 146:58-71.
    • (2004) J Struct Biol , vol.146 , pp. 58-71
    • Sakato, M.1    King, S.M.2
  • 39
    • 0024967876 scopus 로고
    • The cell division cycle of Trypanosoma brucei brucei: timing of event markers and cytoskeletal modulations
    • Sherwin T., Gull K. The cell division cycle of Trypanosoma brucei brucei: timing of event markers and cytoskeletal modulations. Philos Trans R Soc Lond B Biol Sci 1989, 323:573-588.
    • (1989) Philos Trans R Soc Lond B Biol Sci , vol.323 , pp. 573-588
    • Sherwin, T.1    Gull, K.2
  • 40
    • 51449084924 scopus 로고    scopus 로고
    • The history of African trypanosomiasis
    • Steverding D. The history of African trypanosomiasis. Parasit Vectors 2008, 1:3.
    • (2008) Parasit Vectors , vol.1 , pp. 3
    • Steverding, D.1
  • 42
    • 0001158818 scopus 로고
    • Organization of function in trypanosome flagella
    • Walker P.J. Organization of function in trypanosome flagella. Nature 1961, 189:1017-1018.
    • (1961) Nature , vol.189 , pp. 1017-1018
    • Walker, P.J.1
  • 43
    • 0034704084 scopus 로고    scopus 로고
    • Inhibition of Trypanosoma brucei gene expression by RNA interference using an integratable vector with opposing T7 promoters
    • Wang Z., Morris J.C., Drew M.E., Englund P.T. Inhibition of Trypanosoma brucei gene expression by RNA interference using an integratable vector with opposing T7 promoters. J Biol Chem 2000, 275:40174-40179.
    • (2000) J Biol Chem , vol.275 , pp. 40174-40179
    • Wang, Z.1    Morris, J.C.2    Drew, M.E.3    Englund, P.T.4
  • 44
    • 35948979262 scopus 로고    scopus 로고
    • Dyneins across eukaryotes: a comparative genomic analysis
    • Wickstead B., Gull K. Dyneins across eukaryotes: a comparative genomic analysis. Traffic 2007, 8:1708-1721.
    • (2007) Traffic , vol.8 , pp. 1708-1721
    • Wickstead, B.1    Gull, K.2
  • 45
    • 41449086954 scopus 로고    scopus 로고
    • Twenty-five dyneins in Tetrahymena: a re-examination of the multidynein hypothesis
    • Wilkes D.E., Watson H.E., Mitchell D.R., Asai D.J. Twenty-five dyneins in Tetrahymena: a re-examination of the multidynein hypothesis. Cell Motil Cytoskeleton 2008, 65:342-351.
    • (2008) Cell Motil Cytoskeleton , vol.65 , pp. 342-351
    • Wilkes, D.E.1    Watson, H.E.2    Mitchell, D.R.3    Asai, D.J.4
  • 46
    • 34547104215 scopus 로고    scopus 로고
    • Keeping an eye on I1:I1 dynein as a model for flagellar dynein assembly and regulation
    • Wirschell M., Hendrickson T., Sale W.S. Keeping an eye on I1:I1 dynein as a model for flagellar dynein assembly and regulation. Cell Motil Cytoskeleton 2007, 64:569-579.
    • (2007) Cell Motil Cytoskeleton , vol.64 , pp. 569-579
    • Wirschell, M.1    Hendrickson, T.2    Sale, W.S.3
  • 47
    • 0033525524 scopus 로고    scopus 로고
    • A tightly regulated inducible expression system for conditional gene knock-outs and dominant-negative genetics in Trypanosoma brucei
    • Wirtz E., Leal S., Ochatt C., Cross G.A. A tightly regulated inducible expression system for conditional gene knock-outs and dominant-negative genetics in Trypanosoma brucei. Mol Biochem Parasitol 1999, 99:89-101.
    • (1999) Mol Biochem Parasitol , vol.99 , pp. 89-101
    • Wirtz, E.1    Leal, S.2    Ochatt, C.3    Cross, G.A.4
  • 48
    • 29244468544 scopus 로고    scopus 로고
    • An axonemal dynein particularly important for flagellar movement at high viscosity. Implications from a new Chlamydomonas mutant deficient in the dynein heavy chain gene DHC9
    • Yagi T., Minoura I., Fujiwara A., et al. An axonemal dynein particularly important for flagellar movement at high viscosity. Implications from a new Chlamydomonas mutant deficient in the dynein heavy chain gene DHC9. J Biol Chem 2005, 280:41412-41420.
    • (2005) J Biol Chem , vol.280 , pp. 41412-41420
    • Yagi, T.1    Minoura, I.2    Fujiwara, A.3
  • 49
    • 67649668399 scopus 로고    scopus 로고
    • Identification of dyneins that localize exclusively to the proximal portion of Chlamydomonas flagella
    • Yagi T., Uematsu K., Liu Z., Kamiya R. Identification of dyneins that localize exclusively to the proximal portion of Chlamydomonas flagella. J Cell Sci 2009, 122:1306-1314.
    • (2009) J Cell Sci , vol.122 , pp. 1306-1314
    • Yagi, T.1    Uematsu, K.2    Liu, Z.3    Kamiya, R.4
  • 50
    • 40649120193 scopus 로고    scopus 로고
    • Kamiya R. Novel 44-kilodalton subunit of axonemal Dynein conserved from chlamydomonas to mammals
    • Yamamoto R., Yanagisawa H., Yagi T., Kamiya R. Kamiya R. Novel 44-kilodalton subunit of axonemal Dynein conserved from chlamydomonas to mammals. Eukaryot Cell 2008, 7:154-161.
    • (2008) Eukaryot Cell , vol.7 , pp. 154-161
    • Yamamoto, R.1    Yanagisawa, H.2    Yagi, T.3    Kamiya, R.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.